iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

PLoS Computational Biology

Volumn 10, Issue 7, 2014, Pages

  Janky, Rekin's ^a   Verfaillie, Annelien ^a   Imrichová, Hana ^a   van de Sande, Bram ^a   Standaert, Laura ^b   Christiaens, Valerie ^a   Hulselmans, Gert ^a   Herten, Koen ^a   Naval Sanchez, Marina ^a   Potier, Delphine ^a   Svetlichnyy, Dmitry ^a   Kalender Atak, Zeynep ^a   Fiers, Mark ^b   Marine, Jean Christophe ^b   Aerts, Stein ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; PROTEINS; TRANSCRIPTION;

BIOLOGICAL MAPPING; BIOLOGICAL PROCESS; DOWN-STREAM; EXPRESSED GENES; GENE LISTS; GENE NETWORKS; GENE REGULATORY NETWORKS; GENE SETS; MASTER REGULATORS; SYSTEMS BIOLOGY;

RNA;

MICRORNA; NUCLEAR FACTOR Y; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F;

ACCURACY; ANALYTIC METHOD; ARTICLE; BREAST CANCER; CANCER CELL; COMPUTER INTERFACE; COMPUTER PROGRAM; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE TARGETING; GENETIC DATABASE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTERNET; MATHEMATICAL COMPUTING; NOISE; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; UPREGULATION; VALIDATION PROCESS; BIOLOGICAL MODEL; BIOLOGY; BREAST TUMOR; CHROMATIN IMMUNOPRECIPITATION; GENETICS; PROCEDURES; SEQUENCE ANALYSIS; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENES, P53; HUMANS; MODELS, GENETIC; SEQUENCE ANALYSIS, RNA; TRANSCRIPTION FACTORS;

EID: 84905457386     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003731     Document Type: Article

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