An integrative, multi-scale, genome-wide model reveals the phenotypic landscape of Escherichia coli

Molecular Systems Biology

Volumn 10, Issue 7, 2014, Pages

  Carrera, Javier ^a,d   Estrela, Raissa ^b   Luo, Jing ^a   Rai, Navneet ^a   Tsoukalas, Athanasios ^a,c   Tagkopoulos, Ilias ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Davis   (United States)

^d Stanford University   (United States)

Author keywords

genome engineering; genome scale model; model driven experimentation; predictive modeling and integration; systems and synthetic biology

Indexed keywords

CARBON; COBALAMIN; COBALT; CYSTEINE; FERROUS ION; HOMOSERINE; MANGANESE; METAL; METHIONINE; NITROGEN; OXYGEN; PHOSPHATE; RHAMNOSE; SHORT CHAIN FATTY ACID; THREONINE;

ARTICLE; BACTERIUM CULTURE; BIOSYNTHESIS; CARBON SOURCE; CATABOLISM; COST BENEFIT ANALYSIS; ENVIRONMENTAL CHANGE; ESCHERICHIA COLI; GENE EXPRESSION; GENE INACTIVATION; GENETIC MODEL; GENETIC VARIABILITY; GROWTH RATE; ION TRANSPORT; METABOLISM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ADAPTATION; ALGORITHM; BACTERIAL GENOME; BIOLOGICAL MODEL; GENE REGULATORY NETWORK; GENETICS; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROCEDURES; SYSTEMS BIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ALGORITHMS; ESCHERICHIA COLI; GENE REGULATORY NETWORKS; GENOME, BACTERIAL; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; PHENOTYPE; STRESS, PHYSIOLOGICAL; SYSTEMS BIOLOGY;

EID: 84905400331     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20145108     Document Type: Article

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