Noise contributions in an inducible genetic switch: A whole-cell simulation study

PLoS Computational Biology

Volumn 7, Issue 3, 2011, Pages

  Roberts, Elijah ^a,b   Magis, Andrew ^a   Ortiz, Julio O ^c   Baumeister, Wolfgang ^c   Luthey Schulten, Zaida ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b University of Illinois at Urbana Champaign   (United States)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; MAXIMUM LIKELIHOOD ESTIMATION; MOLECULAR BIOLOGY; PROTEINS; STOCHASTIC MODELS; STOCHASTIC SYSTEMS;

CELL SIMULATION; FAST GROWTHS; GENETIC SWITCHES; GROWTH CELLS; GROWTH CONDITIONS; IN-VIVO; NOISE CONTRIBUTIONS; SIMULATION STUDIES; SLOW GROWTH; WHOLE CELL;

RATE CONSTANTS;

MESSENGER RNA;

ARTICLE; BACTERIAL CELL; BINDING AFFINITY; CELL GROWTH; CELL HETEROGENEITY; CELL KINETICS; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOARCHITECTURE; ELECTRON TOMOGRAPHY; ESCHERICHIA COLI; FEEDBACK SYSTEM; FLUORESCENCE ANALYSIS; GENE EXPRESSION REGULATION; GENE LOCATION; GENE SWITCHING; GENETIC ANALYSIS; GENETIC MODEL; IN VITRO STUDY; LACTOSE OPERON; NOISE; NONHUMAN; PHENOTYPE; PREDICTION; PROTEOMICS; SIGNAL NOISE RATIO; SIMULATION; STOCHASTIC MODEL; WHOLE CELL; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; REGULATORY SEQUENCE;

ESCHERICHIA COLI;

COMPUTER SIMULATION; ESCHERICHIA COLI; LAC OPERON; MODELS, GENETIC; PHENOTYPE; REGULATORY ELEMENTS, TRANSCRIPTIONAL;

EID: 79953666361     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002010     Document Type: Article

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