Facile synthetic method for diverse polyfunctionalized imidazoles by means of pd-catalyzed C-H bond arylation of N -methyl-4,5-dibromoimidazole

Journal of Organic Chemistry

Volumn 79, Issue 15, 2014, Pages 7185-7192

  Yamauchi, Takayuki ^a   Shibahara, Fumitoshi ^a   Murai, Toshiaki ^a,b  

^a GIFU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; BROMINE COMPOUNDS; CATALYSIS;

ARYL HALIDES; ARYL IODIDES; ARYLATION REACTIONS; ARYLATIONS; C-H BOND; SELECTIVE REACTIONS; SYNTHETIC METHODS;

PALLADIUM COMPOUNDS;

1 METHYL 2 (4 METHYLPHENYL) 4 (4 TOLYLETHYNYL)IMIDAZOLE; 1 METHYL 2 (4 METHYLPHENYL) 4 PHENYLIMIDAZOLE; 1 METHYL 4 (4 METHYLPHENYL) 2 (1 NAPHTHYL) 5-[(2 THIAZOLYL)AMINOCARBONYL]IMIDAZOLE; 2 (2 BENZOTHIENYL) 4,5 DIBROMO 1 METHYLIMIDAZOLE; 2 (3,5 BIS(TRIFLUOROMETHYL)PHENYL) 4,5 DIBROMO 1 METHYLIMIDAZOLE; 2 (4 ETHOXYCARBONYLPHENYL) 5 FORMYL 4 (4 METHYLPHENYLETHYNYL) 1 METHYLIMIDAZOLE; 4 BENZAMIDO 1 METHYL 2 (4 METHYLPHENYL)IMIDAZOLE; 4 BROMO 1 METHYL 2 (4 METHYLPHENYL)IMIDAZOLE; 4 BROMO 2 (4 ETHOXYCARBONYLPHENYL) 5 FORMYL 1 METHYLIMIDAZOLE; 4 BROMO 5 ETHOXYCARBONYL 1 METHYL 2 (1 NAPHTHYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (1 NAPHTHYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (2 METHYLPHENYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (3 PYRIDYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (4 METHOXYPHENYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (4 METHYLPHENYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 (4 NITROPHENYL)IMIDAZOLE; 4,5 DIBROMO 1 METHYL 2 PHENYLIMDAZOLE; 4,5 DIBROMO 1 METHYL 2 [4 (TRIFLUOROMETHYL)PHENYL]IMIDAZOLE; 4,5 DIBROMO 2 (4 CYANOPHENYL) 1 METHYLIMIDAZOLE; 4,5 DIBROMO 2 (4 ETHOXYCARBONYLPHENYL) 1 METHYLIMIDAZOLE; 5 ETHOXYCARBONYL 1 METHYL 4 (4 METHYLPHENYL) 2 (1 NAPHTHYL)IMIDAZOLE; HALIDE; IMIDAZOLE DERIVATIVE; IODIDE; N METHYL 4,5 DIBROMOIMIDAZOLE; PALLADIUM COMPLEX; UNCLASSIFIED DRUG; COORDINATION COMPOUND; HALOGENATED HYDROCARBON; N-METHYL-4,5-DIBROMOIMIDAZOLE; PALLADIUM;

ARTICLE; ARYLATION; CATALYST; COVALENT BOND; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TRANSFORMATION; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HYDROGEN BOND;

CATALYSIS; COORDINATION COMPLEXES; HYDROCARBONS, HALOGENATED; HYDROGEN BONDING; IMIDAZOLES; MOLECULAR STRUCTURE; PALLADIUM;

EID: 84905396863     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo5013493     Document Type: Article

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