메뉴 건너뛰기




Volumn 20, Issue 8, 2014, Pages 1-11

Sodium binding to hH3R and hH4R — a molecular modeling study

Author keywords

Allosteric binding site; GPCR; hH3R; hH4R; Sodium sensitivity; Subtype differences

Indexed keywords

ADENOSINE A2A RECEPTOR; AMINO ACID; ASPARTIC ACID; G PROTEIN COUPLED RECEPTOR; GLUTAMINE; GLYCINE; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; OXYGEN; SERINE; SODIUM; SODIUM ION; CYSTEINE; HISTAMINE RECEPTOR; HRH4 PROTEIN, HUMAN; ION; MUTANT PROTEIN; SODIUM CHANNEL; SOLVENT;

EID: 84905326897     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-014-2394-2     Document Type: Article
Times cited : (14)

References (41)
  • 2
    • 0037082324 scopus 로고    scopus 로고
    • Target validation of G-protein coupled receptors
    • COI: 1:CAS:528:DC%2BD38XhtFyrs7w%3D
    • Wise A, Gearing K, Rees S (2002) Target validation of G-protein coupled receptors. Drug Discov Today 7:235–246
    • (2002) Drug Discov Today , vol.7 , pp. 235-246
    • Wise, A.1    Gearing, K.2    Rees, S.3
  • 3
    • 33748671369 scopus 로고    scopus 로고
    • The 7TM G-protein-coupled receptor target family
    • COI: 1:CAS:528:DC%2BD2sXjsVCmtbw%3D
    • Jacoby E, Bouhelal R, Gerspacher M, Seuwen K (2006) The 7TM G-protein-coupled receptor target family. Chem Med Chem 1:760–782
    • (2006) Chem Med Chem , vol.1 , pp. 760-782
    • Jacoby, E.1    Bouhelal, R.2    Gerspacher, M.3    Seuwen, K.4
  • 5
    • 37749048627 scopus 로고    scopus 로고
    • 4 receptors in allergic inflammation: the search for new antihistamines
    • COI: 1:CAS:528:DC%2BD1cXht1ygsQ%3D%3D
    • 4 receptors in allergic inflammation: the search for new antihistamines. Nat Rev Drug Discov 7:41–53
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 41-53
    • Thurmond, R.L.1    Gelfand, E.W.2    Dunford, P.P.J.3
  • 7
    • 79954420065 scopus 로고    scopus 로고
    • En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family
    • COI: 1:CAS:528:DC%2BC3MXksFGru7w%3D
    • Leurs R, Vischer HF, Wijtmans M, de Esch IJ (2011) En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family. Trends Pharmacol Sci 32:250–257
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 250-257
    • Leurs, R.1    Vischer, H.F.2    Wijtmans, M.3    de Esch, I.J.4
  • 8
    • 84871788150 scopus 로고    scopus 로고
    • Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs
    • COI: 1:CAS:528:DC%2BC38XhvVWjtbvF
    • Strasser A, Wittmann HJ, Buschauer A, Schneider EH, Seifert R (2013) Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs. Trends Pharmacol Sci 34:13–32
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 13-32
    • Strasser, A.1    Wittmann, H.J.2    Buschauer, A.3    Schneider, E.H.4    Seifert, R.5
  • 10
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • COI: 1:CAS:528:DyaK3sXlslCltr0%3D
    • Lefkowitz RJ, Cotecchia S, Samama P, Costa T (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol Sci 14:303–307
    • (1993) Trends Pharmacol Sci , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 11
    • 0028950255 scopus 로고
    • The two-state model of receptor activation
    • COI: 1:CAS:528:DyaK2MXltlSkurY%3D
    • Leff P (1995) The two-state model of receptor activation. Trends Pharmacol Sci 16:89–97
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 89-97
    • Leff, P.1
  • 12
    • 0026767427 scopus 로고
    • Reverse intrinsic activity of antagonists on G protein-coupled receptors
    • Schütz W, Freissmuth M (1992) Reverse intrinsic activity of antagonists on G protein-coupled receptors. Trends Pharmacol Sci 13:376–380
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 376-380
    • Schütz, W.1    Freissmuth, M.2
  • 13
    • 0036033424 scopus 로고    scopus 로고
    • Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild type receptors
    • COI: 1:CAS:528:DC%2BD38XnvVOqtrY%3D
    • Seifert R, Wenzel-Seifert K (2002) Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild type receptors. Naunyn Schmiedeberg's Arch Pharmacol 366:381–416
    • (2002) Naunyn Schmiedeberg's Arch Pharmacol , vol.366 , pp. 381-416
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 14
    • 0042196012 scopus 로고    scopus 로고
    • The human formyl peptide receptor as model system for constitutively active G-protein-coupled receptors
    • COI: 1:CAS:528:DC%2BD3sXms12hs7Y%3D
    • Seifert R, Wenzel-Seifert K (2003) The human formyl peptide receptor as model system for constitutively active G-protein-coupled receptors. Life Sci 73:2263–2280
    • (2003) Life Sci , vol.73 , pp. 2263-2280
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 15
    • 0034796628 scopus 로고    scopus 로고
    • + as universal stabilizer of the inactive (R) state
    • COI: 1:CAS:528:DC%2BD3MXnsVeksb8%3D
    • + as universal stabilizer of the inactive (R) state. Receptor Channels 7:357–369
    • (2001) Receptor Channels , vol.7 , pp. 357-369
    • Seifert, R.1    Wenzel-Seifert, K.2
  • 16
    • 0032978620 scopus 로고    scopus 로고
    • Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors
    • COI: 1:CAS:528:DyaK1MXhvFOhs7c%3D
    • Martin S, Botto JM, Vincent JP, Mazella J (1999) Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors. Mol Pharmacol 55:210–215
    • (1999) Mol Pharmacol , vol.55 , pp. 210-215
    • Martin, S.1    Botto, J.M.2    Vincent, J.P.3    Mazella, J.4
  • 17
    • 59149087657 scopus 로고    scopus 로고
    • 2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding
    • COI: 1:CAS:528:DC%2BD1MXisFymtw%3D%3D
    • 2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding. J Pharmacol Exp Ther 328:40–54
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 40-54
    • Ericksen, S.S.1    Cummings, D.F.2    Weinstein, H.3    Schetz, J.A.4
  • 18
    • 19944402189 scopus 로고    scopus 로고
    • Allosteric modulation of dopamine receptors
    • COI: 1:CAS:528:DC%2BD2MXkvFGjtLY%3D
    • Schetz JA (2005) Allosteric modulation of dopamine receptors. Mini Rev Med Chem 5:555–561
    • (2005) Mini Rev Med Chem , vol.5 , pp. 555-561
    • Schetz, J.A.1
  • 19
    • 0025852998 scopus 로고
    • 2 receptors by sodium and pH
    • COI: 1:CAS:528:DyaK3MXit1WqsbY%3D
    • 2 receptors by sodium and pH. Mol Pharmacol 39:570–578
    • (1991) Mol Pharmacol , vol.39 , pp. 570-578
    • Neve, K.1
  • 20
    • 77349123734 scopus 로고    scopus 로고
    • 3 receptor function by monovalent ions
    • COI: 1:CAS:528:DC%2BC3cXivFGht7c%3D
    • 3 receptor function by monovalent ions. Neuroscience Lett 472:114–118
    • (2010) Neuroscience Lett , vol.472 , pp. 114-118
    • Schnell, D.1    Seifert, R.2
  • 23
    • 0035144450 scopus 로고    scopus 로고
    • 4 dopamine receptor is coupled to three distinct sites of allosteric modulation
    • COI: 1:CAS:528:DC%2BD3MXoslartg%3D%3D
    • 4 dopamine receptor is coupled to three distinct sites of allosteric modulation. J Pharmacol Exp Ther 296:359–363
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 359-363
    • Schetz, J.A.1    Sibley, D.R.2
  • 24
    • 0027986462 scopus 로고
    • Mutation of an aspartate residue highly conserved among G-protein-coupled receptors results in nonreciprocal disruption of α2-adrenergic receptor-G-protein interactions
    • COI: 1:CAS:528:DyaK2cXmslansb8%3D
    • Ceresa BP, Limbird LE (1994) Mutation of an aspartate residue highly conserved among G-protein-coupled receptors results in nonreciprocal disruption of α2-adrenergic receptor-G-protein interactions. J Biol Chem 269:29557–29564
    • (1994) J Biol Chem , vol.269 , pp. 29557-29564
    • Ceresa, B.P.1    Limbird, L.E.2
  • 26
    • 78049415021 scopus 로고    scopus 로고
    • Induced effects of sodium ions on dopaminergic G-protein coupled receptors
    • Selent J, Sanz F, Pastor M, De Fabritiis G (2010) Induced effects of sodium ions on dopaminergic G-protein coupled receptors. Plos Comput Chem 6:e10000884
    • (2010) Plos Comput Chem , vol.6 , pp. e10000884
    • Selent, J.1    Sanz, F.2    Pastor, M.3    De Fabritiis, G.4
  • 27
    • 84884237285 scopus 로고    scopus 로고
    • The role of water and sodium ions in the activation of the μ-opioid receptor
    • COI: 1:CAS:528:DC%2BC3sXht1Sku7fK
    • Yuan S, Vogel H, Filipek S (2013) The role of water and sodium ions in the activation of the μ-opioid receptor. Angew Chem Int Ed 52:10112–10115
    • (2013) Angew Chem Int Ed , vol.52 , pp. 10112-10115
    • Yuan, S.1    Vogel, H.2    Filipek, S.3
  • 29
  • 30
    • 66649096395 scopus 로고    scopus 로고
    • Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors
    • COI: 1:CAS:528:DC%2BD1MXnt1SqsrY%3D
    • Angel TE, Chance MR, Palczewski K (2009) Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors. PNAS 106:8555–8560
    • (2009) PNAS , vol.106 , pp. 8555-8560
    • Angel, T.E.1    Chance, M.R.2    Palczewski, K.3
  • 33
    • 0029878720 scopus 로고    scopus 로고
    • VMD – visual molecular dynamics
    • COI: 1:CAS:528:DyaK28Xis12nsrg%3D
    • Humphrey W, Dalke A, Schulten K (1996) VMD – visual molecular dynamics. J Mol Graphics 14:33–38
    • (1996) J Mol Graphics , vol.14 , pp. 33-38
    • Humphrey, W.1    Dalke, A.2    Schulten, K.3
  • 34
    • 4444282928 scopus 로고    scopus 로고
    • A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6
    • COI: 1:CAS:528:DC%2BD2cXmvVOhtr4%3D
    • Oostenbrink C, Villa A, Mark AE, van Gunsteren WF (2004) A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6. J Comput Chem 25:1656–1676
    • (2004) J Comput Chem , vol.25 , pp. 1656-1676
    • Oostenbrink, C.1    Villa, A.2    Mark, A.E.3    van Gunsteren, W.F.4
  • 35
    • 0000871204 scopus 로고
    • Multiconfiguration thermodynamic integration
    • COI: 1:CAS:528:DyaK3MXkvF2msb4%3D
    • Straatsma TP, Mc Cammon JA (1991) Multiconfiguration thermodynamic integration. J Chem Phys 95:1175–1188
    • (1991) J Chem Phys , vol.95 , pp. 1175-1188
    • Straatsma, T.P.1    Mc Cammon, J.A.2
  • 36
    • 0037089015 scopus 로고    scopus 로고
    • Calculation of the free energy of solvation for natural analogs of amino acid side chains
    • COI: 1:CAS:528:DC%2BD38XivVaqtLo%3D
    • Villa A, Mark AE (2002) Calculation of the free energy of solvation for natural analogs of amino acid side chains. J Comput Chem 23:548–553
    • (2002) J Comput Chem , vol.23 , pp. 548-553
    • Villa, A.1    Mark, A.E.2
  • 38
    • 84956762558 scopus 로고    scopus 로고
    • 3 receptor. In silico pharmacology, accepted
    • 3 receptor. In silico pharmacology, accepted


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.