Advances in the discovery of N-acylethanolamine acid amidase inhibitors

Pharmacological Research

Volumn 86, Issue , 2014, Pages 11-17

  Bandiera, Tiziano ^a   Ponzano, Stefano ^a   Piomelli, Daniele ^a,b  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fatty acid ethanolamides; Inflammation; N Acylethanolamine acid amidase; NAAA inhibitors; Pain; Palmitoylethanolamide

Indexed keywords

1 HEXADECANOYLPYRROLIDINE; 2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; ALIPHATIC AMINE; AM 9023; ARN 077; BETA LACTONE 2 OXO 3 OXETANYL CARBAMIC ACID BENZYL ESTER; BETA LACTONE DERIVATIVE; CARBAMIC ACID DERIVATIVE; CYCLOBUTANOL; CYCLOPENTYL HEXADECANOATE; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; HOMOMYRISTYLAMINE; LACTONE DERIVATIVE; N ACYLETHANOLAMINE ACID AMIDASE; N ACYLETHANOLAMINE ACID AMIDASE INHIBITOR; N PENTADECYLBENZAMIDE; N PENTADECYLCYCLOHEXANCARBOXAMIDE; PALMIDROL; PALMITIC ACID DERIVATIVE; UNCLASSIFIED DRUG; AMIDASE; ANALGESIC AGENT; ENZYME INHIBITOR; NAAA PROTEIN, HUMAN;

ALLODYNIA; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; CELL STRAIN; DRUG POTENCY; DRUG RESEARCH; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HYPERALGESIA; INFLAMMATION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DEVELOPMENT; METABOLISM; PAIN;

AMIDOHYDROLASES; ANALGESICS; ANIMALS; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; HYPERALGESIA; INFLAMMATION; PAIN;

EID: 84905283599     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.04.011     Document Type: Review

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