N-Cyclohexanecarbonylpentadecylamine: A selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase

Biochemical Journal

Volumn 379, Issue 1, 2004, Pages 99-106

  Tsuboi, Kazuhito ^a   Hilligsmann, Christine ^b   Vandevoorde, Séverine ^b   Lambert, Didier M ^b   Ueda, Natsuo ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Acid amidase; Anandamide; Endocannabinoid; Macrophage; N acylethanolamine; N palmitoylethanolamine

Indexed keywords

ACIDS; ALKALINITY; AMINES; CATALYSIS; CELLS; ENZYME KINETICS; FATTY ACIDS; HYDROLYSIS; PH EFFECTS; PHYSIOLOGY; TISSUE;

ALVEAOLAR MACROPHAGE; BASOPHILIC; BIOACTIVE; ETHANOLAMINE; FATTY ACID AMIDE HYDROLASE; LEUKAEMIA CELLS;

BIOCHEMISTRY;

AMIDASE; AMINE; ENZYME INHIBITOR; FATTY ACID AMIDASE; N CYCLOHEXANECARBONYLPENTADECYLAMINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ENZYME ASSAY; HYDROLYSIS; IC 50; LEUKEMIA CELL; LUNG; LUNG ALVEOLUS MACROPHAGE; MAST CELL LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

AMIDES; AMIDOHYDROLASES; ANIMALS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; LEUKEMIA, BASOPHILIC, ACUTE; LIVER; LUNG; MACROPHAGES, ALVEOLAR; NEOPLASM PROTEINS; ORGAN SPECIFICITY; PALMITIC ACIDS; RATS; RATS, WISTAR; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 1842833388     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031695     Document Type: Article

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