Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds

Journal of Pharmacology and Experimental Therapeutics

Volumn 350, Issue 2, 2014, Pages 313-321

  Pereira, Edna F R ^a   Aracava, Yasco ^a   DeTolla Jr , Louis J ^a   Beecham, E Jeffrey ^b   Basinger Jr , G William ^b   Wakayama, Edgar J ^c   Albuquerque, Edson X ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Program of Comparative Medicine Department of Pathology Medicine and Epidemiology and Public Health University of Maryland School of Medicine ^*  (United States)

^c U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLESTERASE; NERVE GAS; ORGANOPHOSPHATE PESTICIDE; ORGANOPHOSPHORUS COMPOUND; SARIN; SOMAN;

ANIMAL MODEL; ANXIETY; CLINICAL FEATURE; COGNITIVE DEFECT; CONSCIOUSNESS DISORDER; CONVULSION; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; EVENT RELATED POTENTIAL; EVOKED VISUAL RESPONSE; INTOXICATION; LD 50; MOLECULAR MECHANICS; NEUROTOXICITY; NONHUMAN; ORGANOPHOSPHORUS INTOXICATION; PRIORITY JOURNAL; PROTEIN BINDING; RESPIRATORY DISTRESS; REVIEW;

ANIMALS; ANXIETY; ELECTROENCEPHALOGRAPHY; GUINEA PIGS; HUMANS; LETHAL DOSE 50; MAZE LEARNING; MODELS, ANIMAL; ORGANOPHOSPHATE POISONING; ORGANOPHOSPHORUS COMPOUNDS;

EID: 84905049627     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.214932     Document Type: Review

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