Acute toxicity of organophosphorus compounds in Guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition

Journal of Pharmacology and Experimental Therapeutics

Volumn 328, Issue 2, 2009, Pages 516-524

  Fawcett, William P ^a   Aracava, Yasco ^a   Adler, Michael ^b   Pereira, Edna F R ^a   Albuquerque, Edson X ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; ORGANOPHOSPHORUS COMPOUND; SARIN; SOMAN;

ACUTE TOXICITY; AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG MECHANISM; ENZYME INACTIVATION; FEMALE; GUINEA PIG; LD 50; MALE; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE;

ACETYLCHOLINESTERASE; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CHOLINESTERASE INHIBITORS; FEMALE; GUINEA PIGS; MALE; ORGANOPHOSPHORUS COMPOUNDS; SARIN; SEX CHARACTERISTICS; SOMAN;

EID: 59649124122     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.146639     Document Type: Article

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