메뉴 건너뛰기




Volumn 290, Issue 2-3, 2011, Pages 195-202

Gene expression and phosphoprotein profile of certain key neuronal signaling proteins following soman intoxication

Author keywords

Atropine sulphate and diazepam; HI 6; Nerve agents; Phosphorylation; Soman

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ACETYLCHOLINESTERASE; ATROPINE; BRAIN PROTEIN; CASPASE 3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIAZEPAM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; PROTEIN BAX; PROTEIN C FOS; PROTEIN C JUN; SOMAN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; CHEMICAL WARFARE AGENT; CHOLINESTERASE INHIBITOR; OXIME; PYRIDINIUM DERIVATIVE;

EID: 84858618787     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.09.005     Document Type: Article
Times cited : (17)

References (44)
  • 2
    • 67651173003 scopus 로고    scopus 로고
    • Differential mRNA expression of acetylcholinesterase in the central nervous system of rats with acute and chronic exposure of sarin & physostigmine
    • Bansal Iti., Waghmare C., Anand K.A, Gupta T.K., Bhattacharya B.K. Differential mRNA expression of acetylcholinesterase in the central nervous system of rats with acute and chronic exposure of sarin & physostigmine. J. Appl. Toxicol. 2009, 29:386-394.
    • (2009) J. Appl. Toxicol. , vol.29 , pp. 386-394
    • Bansal, I.1    Waghmare, C.2    Anand, K.A.3    Gupta, T.K.4    Bhattacharya, B.K.5
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 1542476889 scopus 로고    scopus 로고
    • Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP Kinases
    • Caughlan A., Newhouse K., Namgung U.K., Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP Kinases. Toxicol. Sci. 2004, 78:125-134.
    • (2004) Toxicol. Sci. , vol.78 , pp. 125-134
    • Caughlan, A.1    Newhouse, K.2    Namgung, U.K.3    Xia, Z.4
  • 7
    • 70349262211 scopus 로고    scopus 로고
    • Molecular and transcriptional responses to sarin exposure
    • Academic Press, San Francisco, R.C. Gupta (Ed.)
    • Damodaran T.V. Molecular and transcriptional responses to sarin exposure. Handbook of Toxicology of Chemical Warfare Agents 2009, 665-682. Academic Press, San Francisco. R.C. Gupta (Ed.).
    • (2009) Handbook of Toxicology of Chemical Warfare Agents , pp. 665-682
    • Damodaran, T.V.1
  • 8
    • 0036203815 scopus 로고    scopus 로고
    • Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound
    • Damodaran T.V., Abdel-Rahman A.A., Suliman H.B., Abou-Donia M.B. Early differential elevation and persistence of phosphorylated cAMP-response element binding protein (p-CREB) in the central nervous system of hens treated with diisopropyl phosphorofluoridate, an OPIDN-causing compound. Neurochem. Res. 2002, 27:183-193.
    • (2002) Neurochem. Res. , vol.27 , pp. 183-193
    • Damodaran, T.V.1    Abdel-Rahman, A.A.2    Suliman, H.B.3    Abou-Donia, M.B.4
  • 9
    • 0034527096 scopus 로고    scopus 로고
    • Early differential induction of c-jun in the central nervous system of hens treated with diisopropylphosphoro-fluoridate (DFP)
    • Damodaran T.V., Rahman A., Abou-Donia M.B. Early differential induction of c-jun in the central nervous system of hens treated with diisopropylphosphoro-fluoridate (DFP). Neurochem. Res. 2000, 25:1579-1586.
    • (2000) Neurochem. Res. , vol.25 , pp. 1579-1586
    • Damodaran, T.V.1    Rahman, A.2    Abou-Donia, M.B.3
  • 11
    • 0028866102 scopus 로고
    • The role of inducible transcription factors in apoptotic nerve cell death
    • Dragunow M., Preston K. The role of inducible transcription factors in apoptotic nerve cell death. Brain Res. Brain Res. Rev. 1995, 21:1-28.
    • (1995) Brain Res. Brain Res. Rev. , vol.21 , pp. 1-28
    • Dragunow, M.1    Preston, K.2
  • 12
    • 0034760772 scopus 로고    scopus 로고
    • Evidence for non acetylcholinesterase targets of organo-phosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality
    • Duysen E., Li G., Xie B.W., Schopfer L.M., Anderson R.S., Broomfield C.A., Lockridge O. Evidence for non acetylcholinesterase targets of organo-phosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality. J. Pharmacol. Exp. Ther. 2001, 299:528-535.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 528-535
    • Duysen, E.1    Li, G.2    Xie, B.W.3    Schopfer, L.M.4    Anderson, R.S.5    Broomfield, C.A.6    Lockridge, O.7
  • 14
    • 0034983562 scopus 로고    scopus 로고
    • Enhanced activity and level of protein kinase A in the spinal cord supernant of diisopropylphosphrofluoridate (DFP) treated hens distribution of protein kinases and phosphatases in spinal cord subcellular fractions
    • Gupta R.P., Abou-Donia M.B. Enhanced activity and level of protein kinase A in the spinal cord supernant of diisopropylphosphrofluoridate (DFP) treated hens distribution of protein kinases and phosphatases in spinal cord subcellular fractions. Mol. Cell. Biochem. 2001, 220:15-23.
    • (2001) Mol. Cell. Biochem. , vol.220 , pp. 15-23
    • Gupta, R.P.1    Abou-Donia, M.B.2
  • 15
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Rev. 1998, 28:370-490.
    • (1998) Brain Res. Rev. , vol.28 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 17
    • 0035051868 scopus 로고    scopus 로고
    • Toxic effects of sarin in rats at three months following single and repeated low-level inhalation exposure
    • Kassa J., Pecka M., Tichy M., Bajgar J., Koupilova M., Herink J., Krocova Z. Toxic effects of sarin in rats at three months following single and repeated low-level inhalation exposure. Pharmacol. Toxicol. 2001, 88:209-219.
    • (2001) Pharmacol. Toxicol. , vol.88 , pp. 209-219
    • Kassa, J.1    Pecka, M.2    Tichy, M.3    Bajgar, J.4    Koupilova, M.5    Herink, J.6    Krocova, Z.7
  • 18
    • 0033063505 scopus 로고    scopus 로고
    • Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission
    • Kaufer D., Friedman A., Seidman S., Soreq H. Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission. Chem. Biol. Interact. 1999, 119-120:349-360.
    • (1999) Chem. Biol. Interact. , pp. 349-360
    • Kaufer, D.1    Friedman, A.2    Seidman, S.3    Soreq, H.4
  • 19
    • 0032191915 scopus 로고    scopus 로고
    • C-Fos as a transcription factor: a stressful (re)view from a functional map
    • Kovacs K.J. c-Fos as a transcription factor: a stressful (re)view from a functional map. Neurochem. Int. 1998, 33:287-297.
    • (1998) Neurochem. Int. , vol.33 , pp. 287-297
    • Kovacs, K.J.1
  • 20
    • 0030726679 scopus 로고    scopus 로고
    • Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology
    • McDonough J.H., Shih T.M. Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology. Neurosci. Biobehav. Rev. 1997, 21:559-579.
    • (1997) Neurosci. Biobehav. Rev. , vol.21 , pp. 559-579
    • McDonough, J.H.1    Shih, T.M.2
  • 21
    • 33645988822 scopus 로고    scopus 로고
    • Virtues and woes of AChE alternative splicing in stress related neuropathologies
    • Meshorer E., Soreq H. Virtues and woes of AChE alternative splicing in stress related neuropathologies. Trends Neurosci. 2006, 29:216-224.
    • (2006) Trends Neurosci. , vol.29 , pp. 216-224
    • Meshorer, E.1    Soreq, H.2
  • 24
    • 0001472256 scopus 로고
    • Review of nerve agent inhibitors and reactivators of acetylcholinesterase
    • Plenum Press, New York, USA, D.M. Quinn, A.S. Balaubramanian, B.P. Doctor, P. Taylor (Eds.)
    • Moore D.H., Clifford C.B., Crawford I.T., Baggett J.M. Review of nerve agent inhibitors and reactivators of acetylcholinesterase. Enzymes of the Cholinesterase Family 1995, 297-303. Plenum Press, New York, USA. D.M. Quinn, A.S. Balaubramanian, B.P. Doctor, P. Taylor (Eds.).
    • (1995) Enzymes of the Cholinesterase Family , pp. 297-303
    • Moore, D.H.1    Clifford, C.B.2    Crawford, I.T.3    Baggett, J.M.4
  • 25
    • 0034763702 scopus 로고    scopus 로고
    • Nicotine induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells
    • Nakayama H., Numakawa T., Ikeuchi T., Hatanaka H. Nicotine induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells. J. Neurochem. 2001, 79:489-498.
    • (2001) J. Neurochem. , vol.79 , pp. 489-498
    • Nakayama, H.1    Numakawa, T.2    Ikeuchi, T.3    Hatanaka, H.4
  • 26
    • 0031172065 scopus 로고    scopus 로고
    • NF-κB: a crucial transcription factor for glial and neuronal cell function
    • O'Neill, Kaltschmidt NF-κB: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci. 1997, 20:252-258.
    • (1997) Trends Neurosci. , vol.20 , pp. 252-258
    • O'Neill1    Kaltschmidt2
  • 28
    • 84858622179 scopus 로고    scopus 로고
    • Activation of mitogen activated protein kinase (MAPK) pathways after soman poisoning in rat cerebellar granule neurons
    • Pejchal J., österreicher J., Kassa J., Tichy A., Mokry J. Activation of mitogen activated protein kinase (MAPK) pathways after soman poisoning in rat cerebellar granule neurons. J. Appl. Toxicol. 2007, 43-48.
    • (2007) J. Appl. Toxicol. , pp. 43-48
    • Pejchal, J.1    österreicher, J.2    Kassa, J.3    Tichy, A.4    Mokry, J.5
  • 29
    • 0028843037 scopus 로고
    • Possible involvement of a neurotrophic factor during the early stages of organophosphate-induced delayed neurotoxicity
    • Pope C., DiLorenzo K., Ehrich M. Possible involvement of a neurotrophic factor during the early stages of organophosphate-induced delayed neurotoxicity. Toxicol. Lett. 1995, 75:111-117.
    • (1995) Toxicol. Lett. , vol.75 , pp. 111-117
    • Pope, C.1    DiLorenzo, K.2    Ehrich, M.3
  • 30
    • 79957457383 scopus 로고    scopus 로고
    • Regional alterations of JNK3 and CaMKII alpha subunit expression in the rat brain after soman poisoning
    • RamaRao G., Waghmare C., Srivastava N., Bhattacharya B.K. Regional alterations of JNK3 and CaMKII alpha subunit expression in the rat brain after soman poisoning. Hum. Exp. Toxicol. 2011, 30(6):448-459.
    • (2011) Hum. Exp. Toxicol. , vol.30 , Issue.6 , pp. 448-459
    • RamaRao, G.1    Waghmare, C.2    Srivastava, N.3    Bhattacharya, B.K.4
  • 31
    • 79958205958 scopus 로고    scopus 로고
    • Soman-induced alterations of protein kinase C isozymes expression in five discrete areas of the rat brain
    • RamaRao G., Waghmare C., Gupta K.A., Bhattacharya K.B.K. Soman-induced alterations of protein kinase C isozymes expression in five discrete areas of the rat brain. Drug Chem. Toxicol. 2011, 34(3):221-232.
    • (2011) Drug Chem. Toxicol. , vol.34 , Issue.3 , pp. 221-232
    • RamaRao, G.1    Waghmare, C.2    Gupta, K.A.3    Bhattacharya, K.B.K.4
  • 32
    • 79955965612 scopus 로고    scopus 로고
    • Changes of protein oxidation, calpain and cytoskeletal proteins (alpha tubulin and pNF-H) levels in rat brain after nerve agent exposure
    • RamaRao G., Acharya J., Bhattacharya B.K. Changes of protein oxidation, calpain and cytoskeletal proteins (alpha tubulin and pNF-H) levels in rat brain after nerve agent exposure. Toxicol. Lett. 2011, 203:227-236.
    • (2011) Toxicol. Lett. , vol.203 , pp. 227-236
    • RamaRao, G.1    Acharya, J.2    Bhattacharya, B.K.3
  • 35
    • 0032852479 scopus 로고    scopus 로고
    • CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • Shaywitz A.J., Greenberg M.E. CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu. Rev. Biochem. 1999, 68:821-861.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 36
    • 0025270328 scopus 로고
    • Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB
    • Sheng M., McFadden G., Greenberg M.E. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 1990, 4:571-582.
    • (1990) Neuron , vol.4 , pp. 571-582
    • Sheng, M.1    McFadden, G.2    Greenberg, M.E.3
  • 37
    • 0037446246 scopus 로고    scopus 로고
    • Control of nerve agent-induced seizures is critical for neuroprotection and survival
    • Shih T.M., Duniho S.M., McDonough J.H. Control of nerve agent-induced seizures is critical for neuroprotection and survival. Toxicol. Appl. Pharmacol. 2003, 188:69-80.
    • (2003) Toxicol. Appl. Pharmacol. , vol.188 , pp. 69-80
    • Shih, T.M.1    Duniho, S.M.2    McDonough, J.H.3
  • 38
    • 0000249736 scopus 로고    scopus 로고
    • Anticholinesterase agents
    • McGraw-Hill Companies, New York, J.G. Hardman, L.E. Limbird, A.G. Gilman (Eds.)
    • Taylor P. Anticholinesterase agents. Goodman and Gilman's The Pharmacological Basis of Therapeutics 2001, 110-129. McGraw-Hill Companies, New York. 10th ed. J.G. Hardman, L.E. Limbird, A.G. Gilman (Eds.).
    • (2001) Goodman and Gilman's The Pharmacological Basis of Therapeutics , pp. 110-129
    • Taylor, P.1
  • 39
    • 61649117446 scopus 로고    scopus 로고
    • Light cycler 480 Real time PCR system: innovative solutions for relative quantification
    • Tellmann G., Olivier G. Light cycler 480 Real time PCR system: innovative solutions for relative quantification. Biochemica 2006, 16-18.
    • (2006) Biochemica , pp. 16-18
    • Tellmann, G.1    Olivier, G.2
  • 40
    • 34147222879 scopus 로고    scopus 로고
    • VX-induced cell death involves activation of caspase-3 in cultured rat cortical neurons
    • Tenn C.C., Wang Y. VX-induced cell death involves activation of caspase-3 in cultured rat cortical neurons. Neurosci. Lett. 2007, 47(2):155-159.
    • (2007) Neurosci. Lett. , vol.47 , Issue.2 , pp. 155-159
    • Tenn, C.C.1    Wang, Y.2
  • 41
    • 0029789994 scopus 로고    scopus 로고
    • Molecular biology of muscarinic acetylcholine receptors
    • Wess J. Molecular biology of muscarinic acetylcholine receptors. Crit. Rev. Neurobiol. 1996, 10:69-99.
    • (1996) Crit. Rev. Neurobiol. , vol.10 , pp. 69-99
    • Wess, J.1
  • 43
    • 0032525143 scopus 로고    scopus 로고
    • Nerve gas-induced seizures: role of acetylcholine in the rapid inducetion of Fos and glial fibrillic acid protein in piriform cortex
    • Zimmer L., Ennis A., Wiley M.R., Shipley G. Nerve gas-induced seizures: role of acetylcholine in the rapid inducetion of Fos and glial fibrillic acid protein in piriform cortex. J. Neurosci. 1998, 18(10):3897-3908.
    • (1998) J. Neurosci. , vol.18 , Issue.10 , pp. 3897-3908
    • Zimmer, L.1    Ennis, A.2    Wiley, M.R.3    Shipley, G.4
  • 44
    • 0006526735 scopus 로고    scopus 로고
    • Nitrone spin trapping compound N-tert-butyl-alpha-phenylnitrone-prevents seizures induced by anticholinestrase
    • Zivin M., Milatovic D., Dettbarn W.D. Nitrone spin trapping compound N-tert-butyl-alpha-phenylnitrone-prevents seizures induced by anticholinestrase. Brain Res. 1999, 11:6158-6162.
    • (1999) Brain Res. , vol.11 , pp. 6158-6162
    • Zivin, M.1    Milatovic, D.2    Dettbarn, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.