Control of nerve agent-induced seizures is critical for neuroprotection and survival

Toxicology and Applied Pharmacology

Volumn 188, Issue 2, 2003, Pages 69-80

  Shih, Tsung Ming ^a   Duniho, Steven M ^a   McDonough, John H ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

Anticholinergic drugs; Anticonvulsant; Diazepam; Lethality; Midazolam; Nerve agents; Neuropathology; Organophosphorus compounds; Seizures; Survival

Indexed keywords

ANTICONVULSIVE AGENT; ATROPINE; BENZODIAZEPINE DERIVATIVE; BIPERIDEN; CHOLINERGIC RECEPTOR BLOCKING AGENT; CYCLOSARIN; DIAZEPAM; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; MIDAZOLAM; NERVE GAS; PRALIDOXIME; PYRIDOSTIGMINE; SARIN; SOMAN; TABUN; TRIHEXYPHENIDYL; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANTICONVULSANT THERAPY; ARTICLE; BRAIN TISSUE; CALCULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; ELECTRODE; ELECTROENCEPHALOGRAM; GUINEA PIG; HISTOPATHOLOGY; LATENT PERIOD; LD 50; LETHALITY; MALE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; SEIZURE; SURVIVAL;

ANIMALIA; CAVIA;

EID: 0037446246     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(03)00019-X     Document Type: Article

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