-
1
-
-
0036781052
-
NF-kappaB regulation in the immune system
-
Li Q, Verma IM. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002;2:725-734
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
3
-
-
33745298519
-
Nuclear factor-κB in cancer development and progression
-
DOI 10.1038/nature04870, PII NATURE04870
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006;441:431-436 (Pubitemid 44050137)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
4
-
-
34247137849
-
Impact of post-translational modifications of proteins on the inflammatory process
-
DOI 10.1042/BST0350281
-
Ito K. Impact of post-translational modifications of proteins on the inflammatory process. Biochem Soc Trans 2007;35:281-283 (Pubitemid 46596490)
-
(2007)
Biochemical Society Transactions
, vol.35
, Issue.2
, pp. 281-283
-
-
Ito, K.1
-
6
-
-
0033038491
-
Activation of phosphatidylinositol 3-kinase in response to interleukin- 1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit
-
Sizemore N, Leung S, Stark GR. Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit. Mol Cell Biol 1999;19:4798-4805 (Pubitemid 29289518)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.7
, pp. 4798-4805
-
-
Sizemore, N.1
Leung, S.2
Stark, G.R.3
-
7
-
-
0033517190
-
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
-
DOI 10.1038/43474
-
Romashkova JA, Makarov SS. NF-kappaB is a target of AKT in antiapoptotic PDGF signalling. Nature 1999;401:86-90. (Pubitemid 29418448)
-
(1999)
Nature
, vol.401
, Issue.6748
, pp. 86-90
-
-
Romashkova, J.A.1
Makarov, S.S.2
-
8
-
-
0345826140
-
Cell Type-specific Expression of the IκB Kinases Determines the Significance of Phosphatidylinositol 3-Kinase/Akt Signaling to NF-κB Activation
-
DOI 10.1074/jbc.M306976200
-
Gustin JA, Ozes ON, Akca H, Pincheira R, Mayo LD, Li Q, Guzman JR, Korgaonkar CK, Donner DB. Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation. J Biol Chem 2004;279:1615-1620 (Pubitemid 38084426)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.3
, pp. 1615-1620
-
-
Gustin, J.A.1
Ozes, O.N.2
Akca, H.3
Pincheira, R.4
Mayo, L.D.5
Li, Q.6
Guzman, J.R.7
Korgaonkar, C.K.8
Donner, D.B.9
-
9
-
-
0033517189
-
NF-κB activation by tumour necrosis factor requires tie Akt serine- Threonine kinase
-
DOI 10.1038/43466
-
Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999;401:82-85 (Pubitemid 29418447)
-
(1999)
Nature
, vol.401
, Issue.6748
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
10
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
DOI 10.1126/science.278.5339.860
-
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li Jw, Young DB, Barbosa M, Mann M, Manning A, Rao A. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-B Activation. Science 1997;278:860-866 (Pubitemid 27467923)
-
(1997)
Science
, vol.278
, Issue.5339
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.W.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
12
-
-
0242664121
-
IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy
-
DOI 10.1128/MCB.23.22.8070-8083.2003
-
Tergaonkar V, Bottero V, Ikawa M, Li Q, Verma IM. IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy. Mol Cell Biol 2003;23:8070-8083 (Pubitemid 37377499)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.22
, pp. 8070-8083
-
-
Tergaonkar, V.1
Bottero, V.2
Ikawa, M.3
Li, Q.4
Verma, I.M.5
-
13
-
-
0032443803
-
The Akt kinase: Molecular determinants of oncogenicity
-
DOI 10.1073/pnas.95.25.14950
-
Aoki M, Batista ,O, Bellacosa ,A, Tsichlis ,P, Vogt ,PK. The Akt kinase: Molecular determinants of oncogenicity. Proc Natl Acad Sci USA 1998;95:14950-14955 (Pubitemid 29003737)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.25
, pp. 14950-14955
-
-
Aoki, M.1
Batista, O.2
Bellacosa, A.3
Tsichlis, P.4
Vogt, P.K.5
-
14
-
-
0002401715
-
Focus assay of Rous sarcoma virus
-
Habel K, Salzman NP. First ed. New York: Academic Press
-
Vogt PK. Focus assay of Rous sarcoma virus In: Habel K, Salzman NP. Fundamental Techniques in Virology, First ed. New York: Academic Press, 1969:198-211.
-
(1969)
Fundamental Techniques in Virology
, pp. 198-211
-
-
Vogt, P.K.1
-
16
-
-
0142091357
-
Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway
-
DOI 10.1073/pnas.2135336100
-
Bader AG, Felts KA, Jiang N, Chang HW, Vogt PK. Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway. Proc Natl Acad Sci USA 2003;100:12384-12389 (Pubitemid 37271569)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.21
, pp. 12384-12389
-
-
Bader, A.G.1
Felts, K.A.2
Jiang, N.3
Chang, H.W.4
Vogt, P.K.5
-
17
-
-
0023336261
-
Avian sarcoma virus 17 carries the jun oncogene
-
Maki Y, Bos TJ, Davis C, Starbuck M, Vogt PK. Avian sarcoma virus 17 carries the jun oncogene. Proc Natl Acad Sci USA 1987;84:2848-2852
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 2848-2852
-
-
Maki, Y.1
Bos, T.J.2
Davis, C.3
Starbuck, M.4
Vogt, P.K.5
-
18
-
-
0014572514
-
Characteristics of two new avian tumor virus subgroups
-
Duff RG, Vogt PK. Characteristics of two new avian tumor virus subgroups. Virology 1969;39:18-30.
-
(1969)
Virology
, vol.39
, pp. 18-30
-
-
Duff, R.G.1
Vogt, P.K.2
-
19
-
-
0034092571
-
The catalytic subunit of phosphoinositide 3-kinase: Requirements for oncogenicity
-
DOI 10.1074/jbc.275.9.6267
-
Aoki M, Schetter C, Himly M, Batista O, Chang HW, Vogt PK. The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity. J Biol Chem 2000;275:6267-6275 (Pubitemid 30129917)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.9
, pp. 6267-6275
-
-
Aoki, M.1
Schetter, C.2
Himly, M.3
Batista, O.4
Chang, H.W.5
Vogt, P.K.6
-
20
-
-
0025059554
-
Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences
-
Bos TJ, Monteclaro FS, Mitsunobu F, Ball AR, Chang CH, Nishimura T, Vogt PK. Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences. Genes & Development 1990;4:1677-1687 (Pubitemid 20352068)
-
(1990)
Genes and Development
, vol.4
, Issue.10
, pp. 1677-1687
-
-
Bos, T.J.1
Monteclaro, F.S.2
Mitsunobu, F.3
Ball Jr., A.R.4
Chang, C.H.W.5
Nishimura, T.6
Vogt, P.K.7
-
21
-
-
0000440912
-
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase
-
DOI 10.1126/science.276.5320.1848
-
Chang HW, Aoki M, Fruman D, Auger KR, Bellacosa A, Tsichlis PN, Cantley LC, Roberts TM, Vogt PK. Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase. Science 1997;276:1848-1850 (Pubitemid 27443659)
-
(1997)
Science
, vol.276
, Issue.5320
, pp. 1848-1850
-
-
Chang, H.W.1
Aoki, M.2
Fruman, D.3
Auger, K.R.4
Bellacosa, A.5
Tsichlis, P.N.6
Cantley, L.C.7
Roberts, T.M.8
Vogt, P.K.9
-
22
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB
-
Madrid LV, Wang CY, Guttridge DC, Schottelius AJ, Baldwin AS, Jr., Mayo MW. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol Cell Biol 2000;20:1626-1638
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1626-1638
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin Jr., A.S.5
Mayo, M.W.6
-
23
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
DOI 10.1016/S1535-6108(03)00303-9
-
Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, Clardy J, Sellers WR, Silver PA. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell 2003;4:463-476 (Pubitemid 38050043)
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
Wojciechowski, C.L.4
Zhao, J.J.5
Roberts, T.M.6
Clardy, J.7
Sellers, W.R.8
Silver, P.A.9
-
24
-
-
3042743988
-
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
-
DOI 10.1158/0008-5472.CAN-04-0343
-
Yang L, Dan HC, Sun M, Liu Q, Sun XM, Feldman RI, Hamilton AD, Polokoff M, Nicosia SV, Herlyn M, Sebti SM, Cheng JQ. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 2004;64:4394-4399 (Pubitemid 38856907)
-
(2004)
Cancer Research
, vol.64
, Issue.13
, pp. 4394-4399
-
-
Yang, L.1
Dan, H.C.2
Sun, M.3
Liu, Q.4
Sun, X.-M.5
Feldman, R.I.6
Hamilton, A.D.7
Polokoff, M.8
Nicosia, S.V.9
Herlyn, M.10
Sebti, S.M.11
Cheng, J.Q.12
-
25
-
-
27544515272
-
Somatic mutation and gain of copy number of PIK3CA in human breast cancer
-
Wu G, Xing M, Mambo E, Huang X, Liu J, Guo Z, Chatterjee A, Goldenberg D, Gollin S, Sukumar S, Trink B, Sidransky D. Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Research 2005;7:R609-R16.
-
(2005)
Breast Cancer Research
, vol.7
-
-
Wu, G.1
Xing, M.2
Mambo, E.3
Huang, X.4
Liu, J.5
Guo, Z.6
Chatterjee, A.7
Goldenberg, D.8
Gollin, S.9
Sukumar, S.10
Trink, B.11
Sidransky, D.12
-
26
-
-
0029664659
-
Inactivation of IκBβ by the tax protein of human T-cell leukemia virus type 1: A potential mechanism for constitutive induction of NF-κB
-
McKinsey TA, Brockman JA, Scherer DC, Al-Murrani SW, Green PL, Ballard DW. Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB. Mol Cell Biol 1996;16:2083-2090 (Pubitemid 26123728)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.5
, pp. 2083-2090
-
-
McKinsey, T.A.1
Brockman, J.A.2
Scherer, D.C.3
Al-Murrani, S.W.4
Green, P.L.5
Ballard, D.W.6
-
27
-
-
0036546501
-
NF-κB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301-310 (Pubitemid 37328783)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.4
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.-W.4
-
28
-
-
10644248286
-
Post-translational modification of RelA(p65) NF-kappaB
-
Campbell KJ, Perkins ND. Post-translational modification of RelA(p65) NF-kappaB. Biochem Soc Trans 2004;32:1087-1089
-
(2004)
Biochem Soc Trans
, Issue.32
, pp. 1087-1089
-
-
Campbell, K.J.1
Perkins, N.D.2
-
29
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
DOI 10.1016/S0092-8674(02)00703-1
-
Ghosh S, Karin M. Missing pieces in the NF-kappaB puzzle. Cell 2002;109 Suppl:S81-96. (Pubitemid 34457854)
-
(2002)
Cell
, vol.109
, Issue.2 SUPPL. 1
-
-
Ghosh, S.1
Karin, M.2
-
30
-
-
0242664264
-
Phosphorylation of Serine 337 of NF-κB p50 is Critical for DNA Binding
-
DOI 10.1074/jbc.M307971200
-
Hou S, Guan H, Ricciardi RP. Phosphorylation of serine 337 of NF-kappaB p50 is critical for DNA binding. J Biol Chem 2003;278:45994-45998 (Pubitemid 37432747)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45994-45998
-
-
Hou, S.1
Guan, H.2
Ricciardi, R.P.3
-
31
-
-
15444363021
-
337 by the protein kinase a catalytic subunit
-
DOI 10.1074/jbc.M412180200
-
Guan H, Hou S, Ricciardi RP. DNA binding of repressor nuclear factor-kappaB p50/p50 depends on phosphorylation of Ser337 by the protein kinase A catalytic subunit. J Biol Chem 2005;280:9957-9962 (Pubitemid 40395844)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 9957-9962
-
-
Guan, H.1
Hou, S.2
Ricciardi, R.P.3
-
32
-
-
0032039076
-
Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong H, Voll RE, Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1998;1:661-671 (Pubitemid 128379244)
-
(1998)
Molecular Cell
, vol.1
, Issue.5
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
33
-
-
0034693133
-
529 is controlled by casein kinase II
-
Wang D, Westerheide SD, Hanson JL, Baldwin AS, Jr. Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II. J Biol Chem 2000;275:32592-32597 (Pubitemid 30797026)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.42
, pp. 32592-32597
-
-
Wang, D.1
Westerheide, S.D.2
Hanson, J.L.3
Baldwin Jr., A.S.4
-
34
-
-
0032589462
-
IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain
-
Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W. IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem 1999;274:30353-30356 (Pubitemid 129576764)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.43
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
35
-
-
0037192829
-
PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit
-
Mayo MW, Madrid LV, Westerheide SD, Jones DR, Yuan XJ, Baldwin AS, Jr., Whang YE. PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit. J Biol Chem 2002;277:11116-11125
-
(2002)
J Biol Chem
, vol.277
, pp. 11116-11125
-
-
Mayo, M.W.1
Madrid, L.V.2
Westerheide, S.D.3
Jones, D.R.4
Yuan, X.J.5
Baldwin Jr., A.S.6
Whang, Y.E.7
-
36
-
-
11144357466
-
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
DOI 10.1016/S0092-8674(04)00302-2, PII S0092867404003022
-
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R, Hung MC. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004;117:225-237 (Pubitemid 38496242)
-
(2004)
Cell
, vol.117
, Issue.2
, pp. 225-237
-
-
Hu, M.C.-T.1
Lee, D.-F.2
Xia, W.3
Golfman, L.S.4
Ou-Yang, F.5
Yang, J.-Y.6
Zou, Y.7
Bao, S.8
Hanada, N.9
Saso, H.10
Kobayashi, R.11
Hung, M.-C.12
-
37
-
-
11244285329
-
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
-
DOI 10.1074/jbc.M409825200
-
Buss H, Dorrie A, Schmitz ML, Hoffmann E, Resch K, Kracht M. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. J Biol Chem 2004;279:55633-55643 (Pubitemid 40068850)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.53
, pp. 55633-55643
-
-
Buss, H.1
Dorrie, A.2
Schmitz, M.L.3
Hoffmann, E.4
Resch, K.5
Kracht, M.6
-
38
-
-
17844386319
-
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
-
DOI 10.1038/nature03491
-
Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 2005;434:1138-1143 (Pubitemid 40663493)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
39
-
-
11244285329
-
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
-
DOI 10.1074/jbc.M409825200
-
Buss H, Dorrie A, Schmitz ML, Hoffmann E, Resch K, Kracht M. Constitutive and Interleukin-1-inducible Phosphorylation of p65 NF-κB at Serine 536 Is Mediated by Multiple Protein Kinases Including IκB Kinase (IKK)-α, IKKβ, IKKε, TRAF Family Member-associated (TANK)-binding Kinase 1 (TBK1), and an Unknown Kinase and Couples p65 to TATA-binding Protein-associated Factor II31-mediated Interleukin-8 Transcription. J Biol Chem 2004;279:55633-55643 (Pubitemid 40068850)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.53
, pp. 55633-55643
-
-
Buss, H.1
Dorrie, A.2
Schmitz, M.L.3
Hoffmann, E.4
Resch, K.5
Kracht, M.6
-
40
-
-
0028116117
-
Structural and functional analysis of the NF-κB p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an α-helical conformation
-
Schmitz M, dos Santos Silva M, Altmann H, Czisch M, Holak T, Baeuerle P. Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation. J Biol Chem 1994;269:25613-25620 (Pubitemid 24336255)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.41
, pp. 25613-25620
-
-
Schmitz, M.L.1
Dos Santos Silva, M.A.2
Altmann, H.3
Czisch, M.4
Holak, T.A.5
Baeuerle, P.A.6
-
41
-
-
0037039665
-
Distinct roles of the IκB kinase α and β subunits in liberating nuclear factor κB (NF-κB) from IκB and in phosphorylating the p65 subunit of NF-κB
-
DOI 10.1074/jbc.M110572200
-
Sizemore N, Lerner N, Dombrowski N, Sakurai H, Stark GR. Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. J Biol Chem 2002;277:3863-3869 (Pubitemid 34968637)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.6
, pp. 3863-3869
-
-
Sizemore, N.1
Lerner, N.2
Dombrowski, N.3
Sakurai, H.4
Stark, G.R.5
-
42
-
-
0037851769
-
IKKβ plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
-
Yang F, Tang E, Guan K, Wang CY. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J Immunol 2003;170:5630-5635 (Pubitemid 36617854)
-
(2003)
Journal of Immunology
, vol.170
, Issue.11
, pp. 5630-5635
-
-
Yang, F.1
Tang, E.2
Guan, K.3
Wang, C.-Y.4
-
43
-
-
0034720896
-
Kinase regulation in inflammatory response
-
Delhase M, Li N, Karin M. Kinase regulation in inflammatory response. Nature 2000;406:367-368
-
(2000)
Nature
, vol.406
, pp. 367-368
-
-
Delhase, M.1
Li, N.2
Karin, M.3
-
44
-
-
4544341116
-
Genetic deletion of glycogen synthase kinase-3β abrogates activation of IκBα kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor
-
DOI 10.1074/jbc.M403449200
-
Takada Y, Fang X, Jamaluddin MS, Boyd DD, Aggarwal BB. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J Biol Chem 2004;279:39541-39554 (Pubitemid 39258221)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.38
, pp. 39541-39554
-
-
Takada, Y.1
Fang, X.2
Jamaluddin, Md.S.3
Boyd, D.D.4
Aggarwal, B.B.5
-
45
-
-
33748127085
-
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-κB activation and cell survival
-
DOI 10.1016/j.ccr.2006.08.007, PII S1535610806002480
-
Ghosh S, Tergaonkar V, Rothlin CV, Correa RG, Bottero V, Bist P, Verma IM, Hunter T. Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. Cancer Cell 2006;10:215-226 (Pubitemid 44311065)
-
(2006)
Cancer Cell
, vol.10
, Issue.3
, pp. 215-226
-
-
Ghosh, S.1
Tergaonkar, V.2
Rothlin, C.V.3
Correa, R.G.4
Bottero, V.5
Bist, P.6
Verma, I.M.7
Hunter, T.8
-
46
-
-
47249125723
-
Differential involvement of IkappaB kinases alpha and beta in cytokine- And insulin-induced mammalian target of rapamycin activation determined by Akt
-
Dan HC, Baldwin AS. Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt. J Immunol 2008;180:7582-7589
-
(2008)
J Immunol
, vol.180
, pp. 7582-7589
-
-
Dan, H.C.1
Baldwin, A.S.2
-
47
-
-
44849117768
-
Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK
-
Dan HC, Cooper MJ, Cogswell PC, Duncan JA, Ting JP, Baldwin AS. Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK. Genes Dev 2008;22:1490-1500
-
(2008)
Genes Dev
, vol.22
, pp. 1490-1500
-
-
Dan, H.C.1
Cooper, M.J.2
Cogswell, P.C.3
Duncan, J.A.4
Ting, J.P.5
Baldwin, A.S.6
-
48
-
-
0035137882
-
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
-
Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB. J Clin Invest 2001;107:241-246
-
(2001)
J Clin Invest
, vol.107
, pp. 241-246
-
-
Baldwin, A.S.1
-
49
-
-
4344612243
-
NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
-
DOI 10.1172/JCI200421358
-
Huber MA, Azoitei N, Baumann B, Grunert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 2004;114:569-581 (Pubitemid 39572107)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.4
, pp. 569-581
-
-
Huber, M.A.1
Azoitei, N.2
Baumann, B.3
Grunert, S.4
Sommer, A.5
Pehamberger, H.6
Kraut, N.7
Beug, H.8
Wirth, T.9
-
50
-
-
0021208005
-
Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel
-
Wilhelmsen KC, Eggleton K, Temin HM. Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel. J Virol 1984;52:172-182 (Pubitemid 14000485)
-
(1984)
Journal of Virology
, vol.52
, Issue.1
, pp. 172-182
-
-
Wilhelmsen, K.C.1
Eggleton, K.2
Temin, H.M.3
-
51
-
-
0033596128
-
Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel
-
Gilmore TD. Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel. Oncogene 1999;18:6925-6937
-
(1999)
Oncogene
, vol.18
, pp. 6925-6937
-
-
Gilmore, T.D.1
-
52
-
-
4644324186
-
NF-κB functions as a tumour promoter in inflammation-associated cancer
-
DOI 10.1038/nature02924
-
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E, Ben-Neriah Y. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004;431:461-466 (Pubitemid 39329586)
-
(2004)
Nature
, vol.431
, Issue.7007
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Uriell-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
53
-
-
4544224979
-
Inhibition of NF-κB in cancer cells converts inflammation- Induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression
-
DOI 10.1016/j.ccr.2004.08.012, PII S153561080400217X
-
Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell 2004;6:297-305. (Pubitemid 39222042)
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 297-305
-
-
Luo, J.-L.1
Maeda, S.2
Hsu, L.-C.3
Yagita, H.4
Karin, M.5
-
54
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004;118:285-296 (Pubitemid 39061110)
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.-W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
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