-
1
-
-
84888110966
-
Assembly factors for the membrane arm of human complex I
-
Andrews B., Carroll J., Ding S., Fearnley I.M., Walker J.E. Assembly factors for the membrane arm of human complex I. Proc. Natl. Acad. Sci. USA 2013, 110:18934-18939.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18934-18939
-
-
Andrews, B.1
Carroll, J.2
Ding, S.3
Fearnley, I.M.4
Walker, J.E.5
-
2
-
-
0242361314
-
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
-
Balbín M., Fueyo A., Tester A.M., Pendás A.M., Pitiot A.S., Astudillo A., Overall C.M., Shapiro S.D., López-Otín C. Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Nat. Genet. 2003, 35:252-257.
-
(2003)
Nat. Genet.
, vol.35
, pp. 252-257
-
-
Balbín, M.1
Fueyo, A.2
Tester, A.M.3
Pendás, A.M.4
Pitiot, A.S.5
Astudillo, A.6
Overall, C.M.7
Shapiro, S.D.8
López-Otín, C.9
-
3
-
-
84859585597
-
The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives
-
Bernstein S.H., Venkatesh S., Li M., Lee J., Lu B., Hilchey S.P., Morse K.M., Metcalfe H.M., Skalska J., Andreeff M., et al. The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives. Blood 2012, 119:3321-3329.
-
(2012)
Blood
, vol.119
, pp. 3321-3329
-
-
Bernstein, S.H.1
Venkatesh, S.2
Li, M.3
Lee, J.4
Lu, B.5
Hilchey, S.P.6
Morse, K.M.7
Metcalfe, H.M.8
Skalska, J.9
Andreeff, M.10
-
4
-
-
80155126156
-
PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis
-
Bhalla K., Hwang B.J., Dewi R.E., Ou L., Twaddel W., Fang H.-B., Vafai S.B., Vazquez F., Puigserver P., Boros L., Girnun G.D. PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Res. 2011, 71:6888-6898.
-
(2011)
Cancer Res.
, vol.71
, pp. 6888-6898
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
Ou, L.4
Twaddel, W.5
Fang, H.-B.6
Vafai, S.B.7
Vazquez, F.8
Puigserver, P.9
Boros, L.10
Girnun, G.D.11
-
5
-
-
73949140415
-
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
-
Bogunovic D., O'Neill D.W., Belitskaya-Levy I., Vacic V., Yu Y.-L., Adams S., Darvishian F., Berman R., Shapiro R., Pavlick A.C., et al. Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival. Proc. Natl. Acad. Sci. USA 2009, 106:20429-20434.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20429-20434
-
-
Bogunovic, D.1
O'Neill, D.W.2
Belitskaya-Levy, I.3
Vacic, V.4
Yu, Y.-L.5
Adams, S.6
Darvishian, F.7
Berman, R.8
Shapiro, R.9
Pavlick, A.C.10
-
6
-
-
0036713692
-
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
-
Bota D.A., Davies K.J. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat. Cell Biol. 2002, 4:674-680.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 674-680
-
-
Bota, D.A.1
Davies, K.J.2
-
7
-
-
15744384860
-
Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
-
Bota D.A., Ngo J.K., Davies K.J. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic. Biol. Med. 2005, 38:665-677.
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 665-677
-
-
Bota, D.A.1
Ngo, J.K.2
Davies, K.J.3
-
8
-
-
84857725402
-
Exploiting the mutanome for tumor vaccination
-
Castle J.C., Kreiter S., Diekmann J., Löwer M., van de Roemer N., de Graaf J., Selmi A., Diken M., Boegel S., Paret C., et al. Exploiting the mutanome for tumor vaccination. Cancer Res. 2012, 72:1081-1091.
-
(2012)
Cancer Res.
, vol.72
, pp. 1081-1091
-
-
Castle, J.C.1
Kreiter, S.2
Diekmann, J.3
Löwer, M.4
van de Roemer, N.5
de Graaf, J.6
Selmi, A.7
Diken, M.8
Boegel, S.9
Paret, C.10
-
9
-
-
84866037559
-
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s
-
Chae Y.C., Caino M.C., Lisanti S., Ghosh J.C., Dohi T., Danial N.N., Villanueva J., Ferrero S., Vaira V., Santambrogio L., et al. Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s. Cancer Cell 2012, 22:331-344.
-
(2012)
Cancer Cell
, vol.22
, pp. 331-344
-
-
Chae, Y.C.1
Caino, M.C.2
Lisanti, S.3
Ghosh, J.C.4
Dohi, T.5
Danial, N.N.6
Villanueva, J.7
Ferrero, S.8
Vaira, V.9
Santambrogio, L.10
-
10
-
-
84879678155
-
Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species
-
Cheng C.-W., Kuo C.-Y., Fan C.-C., Fang W.-C., Jiang S.S., Lo Y.-K., Wang T.-Y., Kao M.-C., Lee A.Y.-L. Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species. Cell Death Dis. 2013, 4:e681.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Cheng, C.-W.1
Kuo, C.-Y.2
Fan, C.-C.3
Fang, W.-C.4
Jiang, S.S.5
Lo, Y.-K.6
Wang, T.-Y.7
Kao, M.-C.8
Lee, A.Y.-L.9
-
11
-
-
33745685054
-
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
-
Cipolat S., Rudka T., Hartmann D., Costa V., Serneels L., Craessaerts K., Metzger K., Frezza C., Annaert W., D'Adamio L., et al. Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell 2006, 126:163-175.
-
(2006)
Cell
, vol.126
, pp. 163-175
-
-
Cipolat, S.1
Rudka, T.2
Hartmann, D.3
Costa, V.4
Serneels, L.5
Craessaerts, K.6
Metzger, K.7
Frezza, C.8
Annaert, W.9
D'Adamio, L.10
-
12
-
-
84884909413
-
Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency
-
Cogliati S., Frezza C., Soriano M.E., Varanita T., Quintana-Cabrera R., Corrado M., Cipolat S., Costa V., Casarin A., Gomes L.C., et al. Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency. Cell 2013, 155:160-171.
-
(2013)
Cell
, vol.155
, pp. 160-171
-
-
Cogliati, S.1
Frezza, C.2
Soriano, M.E.3
Varanita, T.4
Quintana-Cabrera, R.5
Corrado, M.6
Cipolat, S.7
Costa, V.8
Casarin, A.9
Gomes, L.C.10
-
13
-
-
23244447893
-
Tumour biology: senescence in premalignant tumours
-
Collado M., Gil J., Efeyan A., Guerra C., Schuhmacher A.J., Barradas M., Benguría A., Zaballos A., Flores J.M., Barbacid M., et al. Tumour biology: senescence in premalignant tumours. Nature 2005, 436:642.
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguría, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
-
14
-
-
84871311268
-
Subunit-specific incorporation efficiency and kinetics in mitochondrial complex I homeostasis
-
Dieteren C.E.J., Koopman W.J.H., Swarts H.G., Peters J.G.P., Maczuga P., van Gemst J.J., Masereeuw R., Smeitink J.A.M., Nijtmans L.G.J., Willems P.H.G.M. Subunit-specific incorporation efficiency and kinetics in mitochondrial complex I homeostasis. J.Biol. Chem. 2012, 287:41851-41860.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 41851-41860
-
-
Dieteren, C.E.J.1
Koopman, W.J.H.2
Swarts, H.G.3
Peters, J.G.P.4
Maczuga, P.5
van Gemst, J.J.6
Masereeuw, R.7
Smeitink, J.A.M.8
Nijtmans, L.G.J.9
Willems, P.H.G.M.10
-
15
-
-
84861380457
-
Deubiquitinases in cancer: new functions and therapeutic options
-
Fraile J.M., Quesada V., Rodríguez D., Freije J.M.P., López-Otín C. Deubiquitinases in cancer: new functions and therapeutic options. Oncogene 2012, 31:2373-2388.
-
(2012)
Oncogene
, vol.31
, pp. 2373-2388
-
-
Fraile, J.M.1
Quesada, V.2
Rodríguez, D.3
Freije, J.M.P.4
López-Otín, C.5
-
16
-
-
84890187212
-
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas
-
Fraile J.M., Ordóñez G.R., Quirós P.M., Astudillo A., Galván J.A., Colomer D., López-Otín C., Freije J.M.P., Puente X.S. Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas. Oncotarget 2013, 4:1931-1932.
-
(2013)
Oncotarget
, vol.4
, pp. 1931-1932
-
-
Fraile, J.M.1
Ordóñez, G.R.2
Quirós, P.M.3
Astudillo, A.4
Galván, J.A.5
Colomer, D.6
López-Otín, C.7
Freije, J.M.P.8
Puente, X.S.9
-
18
-
-
84892600839
-
Mitochondrial form and function
-
Friedman J.R., Nunnari J. Mitochondrial form and function. Nature 2014, 505:335-343.
-
(2014)
Nature
, vol.505
, pp. 335-343
-
-
Friedman, J.R.1
Nunnari, J.2
-
19
-
-
33947724515
-
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
-
Fukuda R., Zhang H., Kim J.W., Shimoda L., Dang C.V., Semenza G.L. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 2007, 129:111-122.
-
(2007)
Cell
, vol.129
, pp. 111-122
-
-
Fukuda, R.1
Zhang, H.2
Kim, J.W.3
Shimoda, L.4
Dang, C.V.5
Semenza, G.L.6
-
20
-
-
34548446023
-
Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors
-
Granot Z., Kobiler O., Melamed-Book N., Eimerl S., Bahat A., Lu B., Braun S., Maurizi M.R., Suzuki C.K., Oppenheim A.B., Orly J. Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors. Mol. Endocrinol. 2007, 21:2164-2177.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2164-2177
-
-
Granot, Z.1
Kobiler, O.2
Melamed-Book, N.3
Eimerl, S.4
Bahat, A.5
Lu, B.6
Braun, S.7
Maurizi, M.R.8
Suzuki, C.K.9
Oppenheim, A.B.10
Orly, J.11
-
21
-
-
42349115927
-
Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion
-
Gutiérrez-Fernández A., Fueyo A., Folgueras A.R., Garabaya C., Pennington C.J., Pilgrim S., Edwards D.R., Holliday D.L., Jones J.L., Span P.N., et al. Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion. Cancer Res. 2008, 68:2755-2763.
-
(2008)
Cancer Res.
, vol.68
, pp. 2755-2763
-
-
Gutiérrez-Fernández, A.1
Fueyo, A.2
Folgueras, A.R.3
Garabaya, C.4
Pennington, C.J.5
Pilgrim, S.6
Edwards, D.R.7
Holliday, D.L.8
Jones, J.L.9
Span, P.N.10
-
22
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
23
-
-
26444432919
-
Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis
-
Hance N., Ekstrand M.I., Trifunovic A. Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Hum. Mol. Genet. 2005, 14:1775-1783.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1775-1783
-
-
Hance, N.1
Ekstrand, M.I.2
Trifunovic, A.3
-
24
-
-
84876436850
-
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF
-
Haq R., Shoag J., Andreu-Perez P., Yokoyama S., Edelman H., Rowe G.C., Frederick D.T., Hurley A.D., Nellore A., Kung A.L., et al. Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF. Cancer Cell 2013, 23:302-315.
-
(2013)
Cancer Cell
, vol.23
, pp. 302-315
-
-
Haq, R.1
Shoag, J.2
Andreu-Perez, P.3
Yokoyama, S.4
Edelman, H.5
Rowe, G.C.6
Frederick, D.T.7
Hurley, A.D.8
Nellore, A.9
Kung, A.L.10
-
25
-
-
84863553135
-
Identification and functional expression of the mitochondrial pyruvate carrier
-
Herzig S., Raemy E., Montessuit S., Veuthey J.-L., Zamboni N., Westermann B., Kunji E.R.S., Martinou J.-C. Identification and functional expression of the mitochondrial pyruvate carrier. Science 2012, 337:93-96.
-
(2012)
Science
, vol.337
, pp. 93-96
-
-
Herzig, S.1
Raemy, E.2
Montessuit, S.3
Veuthey, J.-L.4
Zamboni, N.5
Westermann, B.6
Kunji, E.R.S.7
Martinou, J.-C.8
-
26
-
-
18444390287
-
Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease
-
Hori O., Ichinoda F., Tamatani T., Yamaguchi A., Sato N., Ozawa K., Kitao Y., Miyazaki M., Harding H.P., Ron D., et al. Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. J.Cell Biol. 2002, 157:1151-1160.
-
(2002)
J.Cell Biol.
, vol.157
, pp. 1151-1160
-
-
Hori, O.1
Ichinoda, F.2
Tamatani, T.3
Yamaguchi, A.4
Sato, N.5
Ozawa, K.6
Kitao, Y.7
Miyazaki, M.8
Harding, H.P.9
Ron, D.10
-
27
-
-
20044370800
-
Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer
-
Hu J., Bianchi F., Ferguson M., Cesario A., Margaritora S., Granone P., Goldstraw P., Tetlow M., Ratcliffe C., Nicholson A.G., et al. Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer. Oncogene 2005, 24:1212-1219.
-
(2005)
Oncogene
, vol.24
, pp. 1212-1219
-
-
Hu, J.1
Bianchi, F.2
Ferguson, M.3
Cesario, A.4
Margaritora, S.5
Granone, P.6
Goldstraw, P.7
Tetlow, M.8
Ratcliffe, C.9
Nicholson, A.G.10
-
28
-
-
84856595714
-
K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis
-
Hu Y., Lu W., Chen G., Wang P., Chen Z., Zhou Y., Ogasawara M., Trachootham D., Feng L., Pelicano H., et al. K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res. 2012, 22:399-412.
-
(2012)
Cell Res.
, vol.22
, pp. 399-412
-
-
Hu, Y.1
Lu, W.2
Chen, G.3
Wang, P.4
Chen, Z.5
Zhou, Y.6
Ogasawara, M.7
Trachootham, D.8
Feng, L.9
Pelicano, H.10
-
29
-
-
4544276735
-
GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I
-
Huang G., Lu H., Hao A., Ng D.C.H., Ponniah S., Guo K., Lufei C., Zeng Q., Cao X. GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I. Mol. Cell. Biol. 2004, 24:8447-8456.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8447-8456
-
-
Huang, G.1
Lu, H.2
Hao, A.3
Ng, D.C.H.4
Ponniah, S.5
Guo, K.6
Lufei, C.7
Zeng, Q.8
Cao, X.9
-
30
-
-
84873428601
-
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
-
Humble M.M., Young M.J., Foley J.F., Pandiri A.R., Travlos G.S., Copeland W.C. Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance. Hum. Mol. Genet. 2013, 22:1017-1025.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 1017-1025
-
-
Humble, M.M.1
Young, M.J.2
Foley, J.F.3
Pandiri, A.R.4
Travlos, G.S.5
Copeland, W.C.6
-
31
-
-
73349088103
-
Metastasis-associated gene expression changes predict poor outcomes in patients with Dukes stage B and C colorectal cancer
-
Jorissen R.N., Gibbs P., Christie M., Prakash S., Lipton L., Desai J., Kerr D., Aaltonen L.A., Arango D., Kruhøffer M., et al. Metastasis-associated gene expression changes predict poor outcomes in patients with Dukes stage B and C colorectal cancer. Clin. Cancer Res. 2009, 15:7642-7651.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 7642-7651
-
-
Jorissen, R.N.1
Gibbs, P.2
Christie, M.3
Prakash, S.4
Lipton, L.5
Desai, J.6
Kerr, D.7
Aaltonen, L.A.8
Arango, D.9
Kruhøffer, M.10
-
32
-
-
84861561418
-
Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease
-
Kita K., Suzuki T., Ochi T. Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease. J.Biol. Chem. 2012, 287:18163-18172.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 18163-18172
-
-
Kita, K.1
Suzuki, T.2
Ochi, T.3
-
33
-
-
84879617853
-
Supercomplex assembly determines electron flux in the mitochondrial electron transport chain
-
Lapuente-Brun E., Moreno-Loshuertos R., Acín-Pérez R., Latorre-Pellicer A., Colás C., Balsa E., Perales-Clemente E., Quirós P.M., Calvo E., Rodríguez-Hernández M.A., et al. Supercomplex assembly determines electron flux in the mitochondrial electron transport chain. Science 2013, 340:1567-1570.
-
(2013)
Science
, vol.340
, pp. 1567-1570
-
-
Lapuente-Brun, E.1
Moreno-Loshuertos, R.2
Acín-Pérez, R.3
Latorre-Pellicer, A.4
Colás, C.5
Balsa, E.6
Perales-Clemente, E.7
Quirós, P.M.8
Calvo, E.9
Rodríguez-Hernández, M.A.10
-
34
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
Larsson N.G., Wang J., Wilhelmsson H., Oldfors A., Rustin P., Lewandoski M., Barsh G.S., Clayton D.A. Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 1998, 18:231-236.
-
(1998)
Nat. Genet.
, vol.18
, pp. 231-236
-
-
Larsson, N.G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
35
-
-
34250164233
-
Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I
-
Lazarou M., McKenzie M., Ohtake A., Thorburn D.R., Ryan M.T. Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I. Mol. Cell. Biol. 2007, 27:4228-4237.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4228-4237
-
-
Lazarou, M.1
McKenzie, M.2
Ohtake, A.3
Thorburn, D.R.4
Ryan, M.T.5
-
36
-
-
1842690145
-
DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate
-
Liu T., Lu B., Lee I., Ondrovicová G., Kutejová E., Suzuki C.K. DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate. J.Biol. Chem. 2004, 279:13902-13910.
-
(2004)
J.Biol. Chem.
, vol.279
, pp. 13902-13910
-
-
Liu, T.1
Lu, B.2
Lee, I.3
Ondrovicová, G.4
Kutejová, E.5
Suzuki, C.K.6
-
37
-
-
84878864199
-
The hallmarks of aging
-
López-Otín C., Blasco M.A., Partridge L., Serrano M., Kroemer G. The hallmarks of aging. Cell 2013, 153:1194-1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
38
-
-
0037434941
-
The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals
-
Lu B., Liu T., Crosby J.A., Thomas-Wohlever J., Lee I., Suzuki C.K. The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals. Gene 2003, 306:45-55.
-
(2003)
Gene
, vol.306
, pp. 45-55
-
-
Lu, B.1
Liu, T.2
Crosby, J.A.3
Thomas-Wohlever, J.4
Lee, I.5
Suzuki, C.K.6
-
39
-
-
84872271398
-
Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease
-
Lu B., Lee J., Nie X., Li M., Morozov Y.I., Venkatesh S., Bogenhagen D.F., Temiakov D., Suzuki C.K. Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease. Mol. Cell 2013, 49:121-132.
-
(2013)
Mol. Cell
, vol.49
, pp. 121-132
-
-
Lu, B.1
Lee, J.2
Nie, X.3
Li, M.4
Morozov, Y.I.5
Venkatesh, S.6
Bogenhagen, D.F.7
Temiakov, D.8
Suzuki, C.K.9
-
40
-
-
78649842154
-
Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM)
-
Matsushima Y., Goto Y., Kaguni L.S. Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM). Proc. Natl. Acad. Sci. USA 2010, 107:18410-18415.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18410-18415
-
-
Matsushima, Y.1
Goto, Y.2
Kaguni, L.S.3
-
41
-
-
84873459097
-
Understanding metabolic regulation and its influence on cell physiology
-
Metallo C.M., Vander Heiden M.G. Understanding metabolic regulation and its influence on cell physiology. Mol. Cell 2013, 49:388-398.
-
(2013)
Mol. Cell
, vol.49
, pp. 388-398
-
-
Metallo, C.M.1
Vander Heiden, M.G.2
-
42
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C., Vredeveld L.C.W., Soengas M.S., Denoyelle C., Kuilman T., van der Horst C.M.A.M., Majoor D.M., Shay J.W., Mooi W.J., Peeper D.S. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005, 436:720-724.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.W.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
van der Horst, C.M.A.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
43
-
-
0012315579
-
-
Cold Spring Harbor Laboratory Press, Woodbury, NY
-
Nagy A., Gertsenstein M., Vintersten K., Behringer R. Manipulating the Mouse Embryo: a Laboratory Manual 2003, Cold Spring Harbor Laboratory Press, Woodbury, NY.
-
(2003)
Manipulating the Mouse Embryo: a Laboratory Manual
-
-
Nagy, A.1
Gertsenstein, M.2
Vintersten, K.3
Behringer, R.4
-
44
-
-
34548162712
-
An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
-
Neufert C., Becker C., Neurath M.F. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat. Protoc. 2007, 2:1998-2004.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 1998-2004
-
-
Neufert, C.1
Becker, C.2
Neurath, M.F.3
-
45
-
-
77953432125
-
Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly
-
Perales-Clemente E., Fernández-Vizarra E., Acín-Pérez R., Movilla N., Bayona-Bafaluy M.P., Moreno-Loshuertos R., Pérez-Martos A., Fernández-Silva P., Enríquez J.A. Five entry points of the mitochondrially encoded subunits in mammalian complex I assembly. Mol. Cell. Biol. 2010, 30:3038-3047.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3038-3047
-
-
Perales-Clemente, E.1
Fernández-Vizarra, E.2
Acín-Pérez, R.3
Movilla, N.4
Bayona-Bafaluy, M.P.5
Moreno-Loshuertos, R.6
Pérez-Martos, A.7
Fernández-Silva, P.8
Enríquez, J.A.9
-
46
-
-
84860505850
-
Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice
-
Quirós P.M., Ramsay A.J., Sala D., Fernández-Vizarra E., Rodríguez F., Peinado J.R., Fernández-García M.S., Vega J.A., Enríquez J.A., Zorzano A., López-Otín C. Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice. EMBO J. 2012, 31:2117-2133.
-
(2012)
EMBO J.
, vol.31
, pp. 2117-2133
-
-
Quirós, P.M.1
Ramsay, A.J.2
Sala, D.3
Fernández-Vizarra, E.4
Rodríguez, F.5
Peinado, J.R.6
Fernández-García, M.S.7
Vega, J.A.8
Enríquez, J.A.9
Zorzano, A.10
López-Otín, C.11
-
47
-
-
84877894013
-
Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients
-
Rodríguez D., Ramsay A.J., Quesada V., Garabaya C., Campo E., Freije J.M.P., López-Otín C. Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients. Hum. Mol. Genet. 2013, 22:2273-2282.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2273-2282
-
-
Rodríguez, D.1
Ramsay, A.J.2
Quesada, V.3
Garabaya, C.4
Campo, E.5
Freije, J.M.P.6
López-Otín, C.7
-
48
-
-
84858791998
-
Mitochondrial quality control: a matter of life and death for neurons
-
Rugarli E.I., Langer T. Mitochondrial quality control: a matter of life and death for neurons. EMBO J. 2012, 31:1336-1349.
-
(2012)
EMBO J.
, vol.31
, pp. 1336-1349
-
-
Rugarli, E.I.1
Langer, T.2
-
49
-
-
37849013557
-
Transcriptome profile of human colorectal adenomas
-
Sabates-Bellver J., Van der Flier L.G., de Palo M., Cattaneo E., Maake C., Rehrauer H., Laczko E., Kurowski M.A., Bujnicki J.M., Menigatti M., et al. Transcriptome profile of human colorectal adenomas. Mol. Cancer Res. 2007, 5:1263-1275.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 1263-1275
-
-
Sabates-Bellver, J.1
Van der Flier, L.G.2
de Palo, M.3
Cattaneo, E.4
Maake, C.5
Rehrauer, H.6
Laczko, E.7
Kurowski, M.A.8
Bujnicki, J.M.9
Menigatti, M.10
-
50
-
-
84874635096
-
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression
-
Santidrian A.F., Matsuno-Yagi A., Ritland M., Seo B.B., LeBoeuf S.E., Gay L.J., Yagi T., Felding-Habermann B. Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression. J.Clin. Invest. 2013, 123:1068-1081.
-
(2013)
J.Clin. Invest.
, vol.123
, pp. 1068-1081
-
-
Santidrian, A.F.1
Matsuno-Yagi, A.2
Ritland, M.3
Seo, B.B.4
LeBoeuf, S.E.5
Gay, L.J.6
Yagi, T.7
Felding-Habermann, B.8
-
51
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
52
-
-
27144537768
-
Novel genes associated with malignant melanoma but not benign melanocytic lesions
-
Talantov D., Mazumder A., Yu J.X., Briggs T., Jiang Y., Backus J., Atkins D., Wang Y. Novel genes associated with malignant melanoma but not benign melanocytic lesions. Clin. Cancer Res. 2005, 11:7234-7242.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 7234-7242
-
-
Talantov, D.1
Mazumder, A.2
Yu, J.X.3
Briggs, T.4
Jiang, Y.5
Backus, J.6
Atkins, D.7
Wang, Y.8
-
53
-
-
70350064588
-
Protein quality control in mitochondria
-
Tatsuta T. Protein quality control in mitochondria. J.Biochem. 2009, 146:455-461.
-
(2009)
J.Biochem.
, vol.146
, pp. 455-461
-
-
Tatsuta, T.1
-
54
-
-
79960659551
-
Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells
-
Tian Q., Li T., Hou W., Zheng J., Schrum L.W., Bonkovsky H.L. Lon peptidase 1 (LONP1)-dependent breakdown of mitochondrial 5-aminolevulinic acid synthase protein by heme in human liver cells. J.Biol. Chem. 2011, 286:26424-26430.
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 26424-26430
-
-
Tian, Q.1
Li, T.2
Hou, W.3
Zheng, J.4
Schrum, L.W.5
Bonkovsky, H.L.6
-
55
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
56
-
-
84876448550
-
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress
-
Vazquez F., Lim J.-H., Chim H., Bhalla K., Girnun G., Pierce K., Clish C.B., Granter S.R., Widlund H.R., Spiegelman B.M., Puigserver P. PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell 2013, 23:287-301.
-
(2013)
Cancer Cell
, vol.23
, pp. 287-301
-
-
Vazquez, F.1
Lim, J.-H.2
Chim, H.3
Bhalla, K.4
Girnun, G.5
Pierce, K.6
Clish, C.B.7
Granter, S.R.8
Widlund, H.R.9
Spiegelman, B.M.10
Puigserver, P.11
-
57
-
-
84855225838
-
Multitasking in the mitochondrion by the ATP-dependent Lon protease
-
Venkatesh S., Lee J., Singh K., Lee I., Suzuki C.K. Multitasking in the mitochondrion by the ATP-dependent Lon protease. Biochim. Biophys. Acta 2012, 1823:56-66.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 56-66
-
-
Venkatesh, S.1
Lee, J.2
Singh, K.3
Lee, I.4
Suzuki, C.K.5
-
58
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 2005, 39:359-407.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
59
-
-
84866665390
-
Mitochondria and cancer
-
Wallace D.C. Mitochondria and cancer. Nat. Rev. Cancer 2012, 12:685-698.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 685-698
-
-
Wallace, D.C.1
-
61
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J., et al. IDH1 and IDH2 mutations in gliomas. N.Engl. J. Med. 2009, 360:765-773.
-
(2009)
N.Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
Kos, I.7
Batinic-Haberle, I.8
Jones, S.9
Riggins, G.J.10
-
62
-
-
77649285631
-
Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2
-
Yang H., Brosel S., Acin-Perez R., Slavkovich V., Nishino I., Khan R., Goldberg I.J., Graziano J., Manfredi G., Schon E.A. Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2. Hum. Mol. Genet. 2010, 19:170-180.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 170-180
-
-
Yang, H.1
Brosel, S.2
Acin-Perez, R.3
Slavkovich, V.4
Nishino, I.5
Khan, R.6
Goldberg, I.J.7
Graziano, J.8
Manfredi, G.9
Schon, E.A.10
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