-
1
-
-
0035851090
-
Nuclear retention of ATM at sites of DNA double strand breaks
-
Andegeko, Y., L. Moyal, L. Mittelman, I. Tsarfaty, Y. Shiloh, and G. Rotman. 2001. Nuclear retention of ATM at sites of DNA double strand breaks. J. Biol. Chem. 276:38224-38230.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38224-38230
-
-
Andegeko, Y.1
Moyal, L.2
Mittelman, L.3
Tsarfaty, I.4
Shiloh, Y.5
Rotman, G.6
-
2
-
-
0032768327
-
Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity
-
Angelis, K.J., M. Dusinská, and A.R. Collins. 1999. Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity. Electrophoresis. 20:2133-2138. http://dx.doi.org/10.1002/(SICI)1522-2683(19990701)20:10<2133::AID-ELPS2133>3.0.CO;2-Q.
-
(1999)
Electrophoresis.
, vol.20
, pp. 2133-2138
-
-
Angelis, K.J.1
Dusinská, M.2
Collins, A.R.3
-
4
-
-
0030740948
-
Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway
-
Bennett, R.A.O., D.M. Wilson III, D. Wong, and B. Demple. 1997. Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. Proc. Natl. Acad. Sci. USA. 94:7166-7169. http://dx.doi.org/10.1073/pnas.94.14.7166.
-
(1997)
Proc. Natl. Acad. Sci. USA.
, vol.94
, pp. 7166-7169
-
-
Bennett, R.A.O.1
Wilson, D.M.2
Wong, D.3
Demple, B.4
-
5
-
-
0025288239
-
Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
-
Beranek, D.T. 1990. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res. 231:11-30. http://dx.doi.org/10.1016/0027-5107(90)90173-2.
-
(1990)
Mutat. Res.
, vol.231
, pp. 11-30
-
-
Beranek, D.T.1
-
6
-
-
0023025598
-
Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis
-
Bianchi, V., E. Pontis, and P. Reichard. 1986. Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis. J. Biol. Chem. 261:16037-16042.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 16037-16042
-
-
Bianchi, V.1
Pontis, B.2
Reichard, P.3
-
7
-
-
0037173449
-
Intrachanges as part of complex chromosome-type exchange aberrations
-
Boei, J.J.W.A., S. Vermeulen, J. Moser, L.H.F. Mullenders, and A.T. Natarajan. 2002. Intrachanges as part of complex chromosome-type exchange aberrations. Mutat. Res. 504:47-55. http://dx.doi.org/10.1016/S0027- 5107(02)00078-7.
-
(2002)
Mutat. Res.
, vol.504
, pp. 47-55
-
-
Boei, J.J.W.A.1
Vermeulen, P.2
Moser, J.3
Mullenders, L.H.F.4
Natarajan, A.T.5
-
8
-
-
44149126949
-
The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR
-
Brem, R., M. Fernet, B. Chapot, and J. Hall. 2008. The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR. DNA Repair (Amst.). 7:849-857. http://dx.doi.org/10.1016/j.dnarep.2008.02.002.
-
(2008)
DNA Repair (Amst.).
, vol.7
, pp. 849-857
-
-
Brem, R.1
Fernet, M.2
Chapot, B.3
Hall, J.4
-
9
-
-
0041378046
-
XRCC1 and DNA strand break repair
-
Caldecott, K.W. 2003. XRCC1 and DNA strand break repair. DNA Repair (Amst.). 2:955-969. http://dx.doi.org/10.1016/S1568-7864(03)00118-6.
-
(2003)
DNA Repair (Amst.).
, vol.2
, pp. 955-969
-
-
Caldecott, K.W.1
-
10
-
-
48249095920
-
Single-strand break repair and genetic disease
-
Caldecott, K.W. 2008. Single-strand break repair and genetic disease. Nat. Rev. Genet. 9:619-631.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 619-631
-
-
Caldecott, K.W.1
-
11
-
-
0029957245
-
XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro
-
Caldecott, K.W., S. Aoufouchi, P. Johnson, and S. Shall. 1996. XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. Nucleic Acids Res. 24:4387-4394. http://dx.doi.org/10.1093/nar/24.22.4387.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 4387-4394
-
-
Caldecott, K.W.1
Aoufouchi, S.2
Johnson, P.3
Shall, S.4
-
12
-
-
84876846651
-
Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1
-
Calvo, J.A., C.A. Moroski-Erkul, A. Lake, L.W. Eichinger, D. Shah, I. Jhun, P. Limsirichai, R.T. Bronson, D.C. Christiani, L.B. Meira, and L.D. Samson. 2013. Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1. PLoS Genet. 9:e1003413. http://dx.doi.org/10.1371/journal.pgen.1003413.
-
(2013)
PLoS Genet.
, vol.9
-
-
Calvo, J.A.1
Moroski-Erkul, C.A.2
Lake, A.3
Eichinger, L.W.4
Shah, D.5
Jhun, I.6
Limsirichai, P.7
Bronson, R.T.8
Christiani, D.C.9
Meira, L.B.10
Samson, L.D.11
-
13
-
-
20644453965
-
XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair
-
Campalans, A., S. Marsin, Y. Nakabeppu, T.R. O'connor, S. Boiteux, and J.P. Radicella. 2005. XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. DNA Repair (Amst.). 4:826-835. http://dx.doi.org/10.1016/j.dnarep.2005.04.014.
-
(2005)
DNA Repair (Amst.).
, vol.4
, pp. 826-835
-
-
Campalans, A.1
Marsin, S.2
Nakabeppu, Y.3
O'connor, T.R.4
Boiteux, S.5
Radicella, J.P.6
-
14
-
-
0023034962
-
Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line
-
Carrano, A.V., J.L. Minkler, L.E. Dillehay, and L.H. Thompson. 1986. Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line. Mutat. Res. 162:233-239. http://dx.doi.org/10.1016/0027-5107(86)90090-4.
-
(1986)
Mutat. Res.
, vol.162
, pp. 233-239
-
-
Carrano, A.V.1
Minkler, J.L.2
Dillehay, L.E.3
Thompson, L.H.4
-
15
-
-
0024411112
-
Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences
-
Ch'ang, L.Y., W.K. Yang, F.E. Myer, and D.M. Yang. 1989. Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences. J. Virol. 63:2746-2757.
-
(1989)
J. Virol.
, vol.63
, pp. 2746-2757
-
-
Ch'ang, L.Y.1
Yang, W.K.2
Myer, F.E.3
Yang, D.M.4
-
16
-
-
0025949662
-
Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase
-
Chakravarti, D., G.C. Ibeanu, K. Tano, and S. Mitra. 1991. Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase. J. Biol. Chem. 266:15710-15715.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 15710-15715
-
-
Chakravarti, D.1
Ibeanu, G.C.2
Tano, K.3
Mitra, S.4
-
17
-
-
57149112500
-
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair
-
Chou, W.C., H.C. Wang, F.H. Wong, S.L. Ding, P.E. Wu, S.Y. Shieh, and C.Y. Shen. 2008. Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair. EMBO J. 27:3140-3150. http://dx.doi.org/10.1038/emboj.2008.229.
-
(2008)
EMBO J.
, vol.27
, pp. 3140-3150
-
-
Chou, W.C.1
Wang, H.C.2
Wong, F.H.3
Ding, S.L.4
Wu, P.E.5
Shieh, S.Y.6
Shen, C.Y.7
-
18
-
-
0028801762
-
Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents-a case of imbalanced DNA repair
-
Coquerelle, T., J. Dosch, and B. Kaina. 1995. Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents-a case of imbalanced DNA repair. Mutat. Res. 336:9-17. http://dx.doi.org/10.1016/0921-8777(94)00035-5.
-
(1995)
Mutat. Res.
, vol.336
, pp. 9-17
-
-
Coquerelle, T.1
Dosch, J.2
Kaina, B.3
-
19
-
-
84876016461
-
Mammalian base excision repair: the forgotten archangel
-
Dianov, G.L., and U. Hübscher. 2013. Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res. 41:3483-3490. http://dx.doi.org/ 10.1093/nar/gkt076.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 3483-3490
-
-
Dianov, G.L.1
Hübscher, U.2
-
20
-
-
0031660080
-
Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate
-
Elder, R.H., J.G. Jansen, R.J. Weeks, M.A. Willington, B. Deans, A.J. Watson, K.J. Mynett, J.A. Bailey, D.P. Cooper, J.A. Rafferty, et al. 1998. Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate. Mol. Cell. Biol. 18:5828-5837.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5828-5837
-
-
Elder, R.H.1
Jansen, J.G.2
Weeks, R.J.3
Willington, M.A.4
Deans, B.5
Watson, A.J.6
Mynett, K.J.7
Bailey, J.A.8
Cooper, D.P.9
Rafferty, J.A.10
-
21
-
-
0032570769
-
A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome
-
Engelward, B.P., J.M. Allan, A.J. Dreslin, J.D. Kelly, M.M. Wu, B. Gold, and L.D. Samson. 1998. A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome. J. Biol. Chem. 273:5412-5418. http://dx.doi.org/10.1074/jbc.273.9.5412.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5412-5418
-
-
Engelward, B.P.1
Allan, J.M.2
Dreslin, A.J.3
Kelly, J.D.4
Wu, M.M.5
Gold, B.6
Samson, L.D.7
-
22
-
-
84961981834
-
Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases
-
Erzberger, J.P., D. Barsky, O.D. Schärer, M.E. Colvin, and D.M. Wilson III. 1998. Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases. Nucleic Acids Res. 26:2771- 2778. http://dx.doi.org/10.1093/nar/26.11.2771.
-
(1998)
Nucleic Acids Res.
, vol.26
-
-
Erzberger, J.P.1
Barsky, D.2
Schärer, O.D.3
Colvin, M.E.4
Wilson, D.M.5
-
23
-
-
0014687685
-
The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis
-
Evans, H.J., and D. Scott. 1969. The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis. Proc. R. Soc. Lond. B Biol. Sci. 173:491-512. http://dx.doi.org/10.1098/rspb.1969.0073.
-
(1969)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.173
, pp. 491-512
-
-
Evans, H.J.1
Scott, D.2
-
24
-
-
0016752877
-
Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction
-
Frei, J.V., and S. Venitt. 1975. Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction. Mutat. Res. 30:89-96. http://dx.doi.org/10.1016/0027-5107(75)90257-2.
-
(1975)
Mutat. Res.
, vol.30
, pp. 89-96
-
-
Frei, J.V.1
Venitt, S.2
-
25
-
-
77956170813
-
Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage
-
Groth, P., S. Ausländer, M.M. Majumder, N. Schultz, F. Johansson, E. Petermann, and T. Helleday. 2010. Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage. J. Mol. Biol. 402:70-82. http://dx.doi.org/10.1016/j.jmb.2010.07.010.
-
(2010)
J. Mol. Biol.
, vol.402
, pp. 70-82
-
-
Groth, P.1
Ausländer, S.2
Majumder, M.M.3
Schultz, N.4
Johansson, F.5
Petermann, E.6
Helleday, T.7
-
26
-
-
84864933506
-
Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
-
Groth, P., M.L. Orta, I. Elvers, M.M. Majumder, A. Lagerqvist, and T. Helleday. 2012. Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation. Nucleic Acids Res. 40:6585-6594. http://dx.doi.org/10.1093/nar/gks315.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 6585-6594
-
-
Groth, P.1
Orta, M.L.2
Elvers, I.3
Majumder, M.M.4
Lagerqvist, A.5
Helleday, T.6
-
27
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu, H., J.D. Marth, P.C. Orban, H. Mossmann, and K. Rajewsky. 1994. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science. 265:103-106. http://dx.doi.org/10.1126/science.8016642.
-
(1994)
Science.
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
28
-
-
35848930133
-
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
-
Hanada, K., M. Budzowska, S.L. Davies, E. van Drunen, H. Onizawa, H.B. Beverloo, A. Maas, J. Essers, I.D. Hickson, and R. Kanaar. 2007. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nat. Struct. Mol. Biol. 14:1096-1104. http://dx.doi.org/10.1038/nsmb1313.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1096-1104
-
-
Hanada, K.1
Budzowska, M.2
Davies, S.L.3
van Drunen, E.4
Onizawa, H.5
Beverloo, H.B.6
Maas, A.7
Essers, J.8
Hickson, I.D.9
Kanaar, R.10
-
29
-
-
33845330910
-
Replisome assembly and the direct restart of stalled replication forks
-
Heller, R.C., and K.J. Marians. 2006. Replisome assembly and the direct restart of stalled replication forks. Nat. Rev. Mol. Cell Biol. 7:932-943. http://dx.doi.org/10.1038/nrm2058.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 932-943
-
-
Heller, R.C.1
Marians, K.J.2
-
30
-
-
78149425175
-
Regulation of homologous recombination in eukaryotes
-
Heyer, W.D., K.T. Ehmsen, and J. Liu. 2010. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 44:113-139. http://dx.doi.org/10.1146/annurev-genet-051710-150955.
-
(2010)
Annu. Rev. Genet.
, vol.44
, pp. 113-139
-
-
Heyer, W.D.1
Ehmsen, K.T.2
Liu, J.3
-
31
-
-
38049183244
-
XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks
-
Horton, J.K., M. Watson, D.F. Stefanick, D.T. Shaughnessy, J.A. Taylor, and S.H. Wilson. 2008. XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Cell Res. 18:48-63. http://dx.doi.org/10.1038/cr.2008.7.
-
(2008)
Cell Res.
, vol.18
, pp. 48-63
-
-
Horton, J.K.1
Watson, M.2
Stefanick, D.F.3
Shaughnessy, D.T.4
Taylor, J.A.5
Wilson, S.H.6
-
32
-
-
0026465075
-
Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells
-
Ibeanu, G., B. Hartenstein, W.C. Dunn, L.Y. Chang, E. Hofmann, T. Coquerelle, S. Mitra, and B. Kaina. 1992. Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells. Carcinogenesis. 13:1989-1995. http://dx.doi.org/10.1093/carcin/13.11.1989.
-
(1992)
Carcinogenesis.
, vol.13
, pp. 1989-1995
-
-
Ibeanu, G.1
Hartenstein, B.2
Dunn, W.C.3
Chang, L.Y.4
Hofmann, E.5
Coquerelle, T.6
Mitra, S.7
Kaina, B.8
-
33
-
-
0032480042
-
Critical steps in alkylation-induced aberration formation
-
Kaina, B. 1998. Critical steps in alkylation-induced aberration formation. Mutat. Res. 404:119-124. http://dx.doi.org/10.1016/S0027-5107(98)00103-1.
-
(1998)
Mutat. Res.
, vol.404
, pp. 119-124
-
-
Kaina, B.1
-
34
-
-
2642574948
-
Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go
-
Kaina, B. 2004. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go. Cytogenet. Genome Res. 104:77-86. http://dx.doi.org/10.1159/000077469.
-
(2004)
Cytogenet. Genome Res.
, vol.104
, pp. 77-86
-
-
Kaina, B.1
-
35
-
-
0022363977
-
Methylation-induced blocks to in vitro DNA replication
-
Larson, K., J. Sahm, R. Shenkar, and B. Strauss. 1985. Methylation-induced blocks to in vitro DNA replication. Mutat. Res. 150:77-84. http://dx.doi.org/10.1016/0027-5107(85)90103-4.
-
(1985)
Mutat. Res.
, vol.150
, pp. 77-84
-
-
Larson, K.1
Sahm, J.2
Shenkar, R.3
Strauss, B.4
-
36
-
-
0032694518
-
Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents
-
Liu, L., P. Taverna, C.M. Whitacre, S. Chatterjee, and S.L. Gerson. 1999. Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents. Clin. Cancer Res. 5:2908-2917.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2908-2917
-
-
Liu, L.1
Taverna, P.2
Whitacre, C.M.3
Chatterjee, S.4
Gerson, S.L.5
-
37
-
-
77953166592
-
gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization
-
Löbrich, M., A. Shibata, A. Beucher, A. Fisher, M. Ensminger, A.A. Goodarzi, O. Barton, and P.A. Jeggo. 2010. gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle. 9:662-669. http://dx.doi.org/10.4161/cc.9.4.10764.
-
(2010)
Cell Cycle.
, vol.9
, pp. 662-669
-
-
Löbrich, M.1
Shibata, A.2
Beucher, A.3
Fisher, A.4
Ensminger, M.5
Goodarzi, A.A.6
Barton, O.7
Jeggo, P.A.8
-
38
-
-
79955635887
-
Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease
-
Ma, W.J., J.W. Westmoreland, D.A. Gordenin, and M.A. Resnick. 2011. Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease. PLoS Genet. 7:e1002059. http://dx.doi.org/10.1371/journal.pgen.1002059.
-
(2011)
PLoS Genet.
, vol.7
-
-
Ma, W.J.1
Westmoreland, J.W.2
Gordenin, D.A.3
Resnick, M.A.4
-
39
-
-
0031844311
-
XRCC1 is specifically associated with poly(ADPribose) polymerase and negatively regulates its activity following DNA damage
-
Masson, M., C. Niedergang, V. Schreiber, S. Muller, J. Menissier-de Murcia, and G. de Murcia. 1998. XRCC1 is specifically associated with poly(ADPribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol. 18:3563-3571.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3563-3571
-
-
Masson, M.1
Niedergang, C.2
Schreiber, V.3
Muller, S.4
Menissier-de Murcia, J.5
de Murcia, G.6
-
40
-
-
77957168933
-
Eukaryotic DNA replication origins: many choices for appropriate answers
-
Méchali, M. 2010. Eukaryotic DNA replication origins: many choices for appropriate answers. Nat. Rev. Mol. Cell Biol. 11:728-738. http://dx.doi.org/10.1038/nrm2976.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 728-738
-
-
Méchali, M.1
-
41
-
-
58849095932
-
Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice
-
Meira, L.B., C.A. Moroski-Erkul, S.L. Green, J.A. Calvo, R.T. Bronson, D. Shah, and L.D. Samson. 2009. Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice. Proc. Natl. Acad. Sci. USA. 106:888-893. http://dx.doi.org/10.1073/pnas.0807030106.
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 888-893
-
-
Meira, L.B.1
Moroski-Erkul, C.A.2
Green, S.L.3
Calvo, J.A.4
Bronson, R.T.5
Shah, D.6
Samson, L.D.7
-
42
-
-
0021592929
-
Molecular mechanisms involved in the production of chromosomal aberrations III. Restriction endonucleases
-
Natarajan, A.T., and G. Obe. 1984. Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases. Chromosoma. 90:120-127. http://dx.doi.org/10.1007/BF00292448.
-
(1984)
Chromosoma
, vol.90
, pp. 120-127
-
-
Natarajan, A.T.1
Obe, G.2
-
43
-
-
0020956536
-
Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells
-
Natarajan, A.T., A.D. Tates, M. Meijers, I. Neuteboom, and N. de Vogel. 1983. Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells. An evaluation of methodology for detection of SCEs and of persistent DNA lesions towards the frequencies of observed SCEs. Mutat. Res. 121:211-223. http://dx.doi.org/10.1016/0165-7992(83)90206-3.
-
(1983)
An evaluation of methodology for detection of SCEs and of persistent DNA lesions towards the frequencies of observed SCEs. Mutat. Res.
, vol.121
, pp. 211-223
-
-
Natarajan, A.T.1
Tates, A.D.2
Meijers, M.3
Neuteboom, I.4
de Vogel, N.5
-
44
-
-
0022259763
-
Induction of sister-chromatid exchanges by restriction endonucleases
-
Natarajan, A.T., L.H.F. Mullenders, M. Meijers, and U. Mukherjee. 1985. Induction of sister-chromatid exchanges by restriction endonucleases. Mutat. Res. 144:33-39. http://dx.doi.org/10.1016/0165-7992(85)90121-6.
-
(1985)
Mutat. Res.
, vol.144
, pp. 33-39
-
-
Natarajan, A.T.1
Mullenders, L.H.F.2
Meijers, M.3
Mukherjee, U.4
-
45
-
-
34548387438
-
Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique
-
Nazarkina, ZhK., S.N. Khodyreva, S. Marsin, J.P. Radicella, and O.I. Lavrik. 2007. Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique. Biochemistry Mosc. 72:878-886. http://dx.doi.org/10.1134/S000629790708010X.
-
(2007)
Biochemistry Mosc.
, vol.72
, pp. 878-886
-
-
Nazarkina, Z.K.1
Khodyreva, S.N.2
Marsin, S.3
Radicella, J.P.4
Lavrik, O.I.5
-
46
-
-
77957293431
-
Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate
-
Nikolova, T., M. Ensminger, M. Löbrich, and B. Kaina. 2010. Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate. DNA Repair (Amst.). 9:1050-1063. http://dx.doi.org/10.1016/j.dnarep.2010.07.005.
-
(2010)
DNA Repair (Amst.).
, vol.9
, pp. 1050-1063
-
-
Nikolova, T.1
Ensminger, M.2
Löbrich, M.3
Kaina, B.4
-
47
-
-
1642411206
-
Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase
-
O'Brien, P.J., and T. Ellenberger. 2004. Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase. J. Biol. Chem. 279:9750- 9757. http://dx.doi.org/10.1074/jbc.M312232200.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
O'Brien, P.J.1
Ellenberger, T.2
-
48
-
-
0345073699
-
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
-
O'Driscoll, M., V.L. Ruiz-Perez, C.G. Woods, P.A. Jeggo, and J.A. Goodship. 2003. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat. Genet. 33:497-501. http://dx.doi.org/10.1038/ng1129.
-
(2003)
Nat. Genet.
, vol.33
, pp. 497-501
-
-
O'Driscoll, M.1
Ruiz-Perez, V.L.2
Woods, C.G.3
Jeggo, P.A.4
Goodship, J.A.5
-
49
-
-
84876730678
-
Co-ordination of base excision repair and genome stability
-
Parsons, J.L., and G.L. Dianov. 2013. Co-ordination of base excision repair and genome stability. DNA Repair (Amst.). 12:326-333. http://dx.doi.org/10.1016/j.dnarep.2013.02.001.
-
(2013)
DNA Repair (Amst.).
, vol.12
, pp. 326-333
-
-
Parsons, J.L.1
Dianov, G.L.2
-
50
-
-
13744258586
-
The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells
-
Pascucci, B., M.T. Russo, M. Crescenzi, M. Bignami, and E. Dogliotti. 2005. The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells. Nucleic Acids Res. 33:280-288. http://dx.doi.org/10.1093/nar/gki168.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 280-288
-
-
Pascucci, B.1
Russo, M.T.2
Crescenzi, M.3
Bignami, M.4
Dogliotti, E.5
-
51
-
-
76849109722
-
Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
-
Petermann, E., M.L. Orta, N. Issaeva, N. Schultz, and T. Helleday. 2010. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol. Cell. 37:492-502. http://dx.doi.org/10.1016/j.molcel.2010.01.021.
-
(2010)
Mol. Cell.
, vol.37
, pp. 492-502
-
-
Petermann, E.1
Orta, M.L.2
Issaeva, N.3
Schultz, N.4
Helleday, T.5
-
52
-
-
0017354552
-
Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster
-
Pimpinelli, S., D. Pignone, G. Santini, M. Gatti, and G. Olivieri. 1977. Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster. Genetics. 85:249-257.
-
(1977)
Genetics.
, vol.85
, pp. 249-257
-
-
Pimpinelli, S.1
Pignone, D.2
Santini, G.3
Gatti, M.4
Olivieri, G.5
-
53
-
-
79953708229
-
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
-
Quennet, V., A. Beucher, O. Barton, S. Takeda, and M. Löbrich. 2011. CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res. 39:2144-2152. http://dx.doi.org/10.1093/nar/gkq1175.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 2144-2152
-
-
Quennet, V.1
Beucher, A.2
Barton, O.3
Takeda, S.4
Löbrich, M.5
-
54
-
-
84859789451
-
Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors
-
Rai, G., V.N. Vyjayanti, D. Dorjsuren, A. Simeonov, A. Jadhav, D.M. Wilson III, and D.J. Maloney. 2012. Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors. J. Med. Chem. 55:3101-3112. http://dx.doi.org/10.1021/jm201537d.
-
(2012)
J. Med. Chem.
, vol.55
, pp. 3101-3112
-
-
Rai, G.1
Vyjayanti, V.N.2
Dorjsuren, D.3
Simeonov, A.4
Jadhav, A.5
Wilson, D.M.6
Maloney, D.J.7
-
55
-
-
0035898405
-
Characterization of homologous recombination induced by replication inhibition in mammalian cells
-
Saintigny, Y., F. Delacôte, G. Varès, F. Petitot, S. Lambert, D. Averbeck, and B.S. Lopez. 2001. Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J. 20:3861-3870. http://dx.doi.org/10.1093/emboj/20.14.3861.
-
(2001)
EMBO J.
, vol.20
, pp. 3861-3870
-
-
Saintigny, Y.1
Delacôte, F.2
Varès, G.3
Petitot, F.4
Lambert, S.5
Averbeck, D.6
Lopez, B.S.7
-
56
-
-
23344444636
-
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
-
Saleh-Gohari, N., H.E. Bryant, N. Schultz, K.M. Parker, T.N. Cassel, and T. Helleday. 2005. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol. 25:7158-7169. http://dx.doi.org/10.1128/MCB.25.16.7158-7169.2005.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7158-7169
-
-
Saleh-Gohari, N.1
Bryant, H.E.2
Schultz, N.3
Parker, K.M.4
Cassel, T.N.5
Helleday, T.6
-
57
-
-
0032519294
-
Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair
-
Shen, M.R., M.Z. Zdzienicka, H. Mohrenweiser, L.H. Thompson, and M.P. Thelen. 1998. Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair. Nucleic Acids Res. 26:1032-1037. http://dx.doi.org/10.1093/nar/26.4.1032.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 1032-1037
-
-
Shen, M.R.1
Zdzienicka, M.Z.2
Mohrenweiser, H.3
Thompson, L.H.4
Thelen, M.P.5
-
58
-
-
0030030379
-
Requirement of mammalian DNA polymerase-beta in base-excision repair
-
Sobol, R.W., J.K. Horton, R. Kühn, H. Gu, R.K. Singhal, R. Prasad, K. Rajewsky, and S.H. Wilson. 1996. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature. 379:183-186. http://dx.doi.org/10.1038/379183a0.
-
(1996)
Nature.
, vol.379
, pp. 183-186
-
-
Sobol, R.W.1
Horton, J.K.2
Kühn, R.3
Gu, H.4
Singhal, R.K.5
Prasad, R.6
Rajewsky, K.7
Wilson, S.H.8
-
59
-
-
0032516831
-
Mammalian abasic site base excision repair
-
Srivastava, D.K., B.J. Berg, R. Prasad, J.T. Molina, W.A. Beard, A.E. Tomkinson, and S.H. Wilson. 1998. Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J. Biol. Chem. 273:21203-21209. http://dx.doi.org/10.1074/jbc.273.33.21203.
-
(1998)
Identification of the reaction sequence and rate-determining steps. J. Biol. Chem.
, vol.273
, pp. 21203-21209
-
-
Srivastava, D.K.1
Berg, B.J.2
Prasad, R.3
Molina, J.T.4
Beard, W.A.5
Tomkinson, A.E.6
Wilson, S.H.7
-
60
-
-
0034124053
-
Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5?-phosphorylated DNA double-strand breaks by replication runoff
-
Strumberg, D., A.A. Pilon, M. Smith, R. Hickey, L. Malkas, and Y. Pommier. 2000. Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5?-phosphorylated DNA double-strand breaks by replication runoff. Mol. Cell. Biol. 20:3977-3987. http://dx.doi.org/10.1128/MCB.20.11.3977-3987.2000.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3977-3987
-
-
Strumberg, D.1
Pilon, A.A.2
Smith, M.3
Hickey, R.4
Malkas, L.5
Pommier, Y.6
-
61
-
-
0035837590
-
Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells
-
Taverna, P., L. Liu, H.S. Hwang, A.J. Hanson, T.J. Kinsella, and S.L. Gerson. 2001. Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells. Mutat. Res. 485:269-281. http://dx.doi.org/10.1016/S0921-8777(01)00076-3.
-
(2001)
Mutat. Res.
, vol.485
, pp. 269-281
-
-
Taverna, P.1
Liu, L.2
Hwang, H.S.3
Hanson, A.J.4
Kinsella, T.J.5
Gerson, S.L.6
-
62
-
-
0019956767
-
A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange
-
Thompson, L.H., K.W. Brookman, L.E. Dillehay, A.V. Carrano, J.A. Mazrimas, C.L. Mooney, and J.L. Minkler. 1982. A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange. Mutat. Res. 95:427-440. http://dx.doi.org/10.1016/0027-5107(82)90276-7.
-
(1982)
Mutat. Res.
, vol.95
, pp. 427-440
-
-
Thompson, L.H.1
Brookman, K.W.2
Dillehay, L.E.3
Carrano, A.V.4
Mazrimas, J.A.5
Mooney, C.L.6
Minkler, J.L.7
-
63
-
-
0032102896
-
DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines
-
Trucco, C., F.J. Oliver, G. de Murcia, and J. Ménissier-de Murcia. 1998. DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines. Nucleic Acids Res. 26:2644-2649. http://dx.doi.org/10.1093/nar/26.11.2644.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2644-2649
-
-
Trucco, C.1
Oliver, F.J.2
de Murcia, G.3
Ménissier-de Murcia, J.4
-
64
-
-
0035890069
-
XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
-
Vidal, A.E., S. Boiteux, I.D. Hickson, and J.P. Radicella. 2001. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. EMBO J. 20:6530-6539. http://dx.doi.org/10.1093/emboj/20.22.6530.
-
(2001)
EMBO J.
, vol.20
, pp. 6530-6539
-
-
Vidal, A.E.1
Boiteux, S.2
Hickson, I.D.3
Radicella, J.P.4
-
65
-
-
0035846899
-
XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
-
Whitehouse, C.J., R.M. Taylor, A. Thistlethwaite, H. Zhang, F. Karimi-Busheri, D.D. Lasko, M. Weinfeld, and K.W. Caldecott. 2001. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell. 104:107-117. http://dx.doi.org/10.1016/S0092-8674(01)00195-7.
-
(2001)
Cell.
, vol.104
, pp. 107-117
-
-
Whitehouse, C.J.1
Taylor, R.M.2
Thistlethwaite, A.3
Zhang, H.4
Karimi-Busheri, F.5
Lasko, D.D.6
Weinfeld, M.7
Caldecott, K.W.8
-
66
-
-
33845726097
-
Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks
-
Wyatt, M.D., and D.L. Pittman. 2006. Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. Chem. Res. Toxicol. 19:1580-1594. http://dx.doi.org/10.1021/tx060164e.
-
(2006)
Chem. Res. Toxicol.
, vol.19
, pp. 1580-1594
-
-
Wyatt, M.D.1
Pittman, D.L.2
-
67
-
-
0026651211
-
A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges
-
Zdzienicka, M.Z., G.P. van der Schans, A.T. Natarajan, L.H. Thompson, I. Neuteboom, and J.W.I.M. Simons. 1992. A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges. Mutagenesis. 7:265-269. http://dx.doi.org/10.1093/mutage/7.4.265.
-
(1992)
Mutagenesis.
, vol.7
, pp. 265-269
-
-
Zdzienicka, M.Z.1
van der Schans, G.P.2
Natarajan, A.T.3
Thompson, L.H.4
Neuteboom, I.5
Simons, J.W.I.M.6
-
68
-
-
33645979960
-
DNA damage evaluated by gamma H2AX foci formation by a selective group of chemical/physical stressors
-
Zhou, C.X., Z.X. Li, H.L. Diao, Y.K. Yu, W. Zhu, Y.Y. Dai, F.F. Chen, and J. Yang. 2006. DNA damage evaluated by gamma H2AX foci formation by a selective group of chemical/physical stressors. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 604:8-18. http://dx.doi.org/10.1016/j.mrgentox.2005.12.004.
-
(2006)
Mutat. Res. Genet. Toxicol. Environ. Mutagen.
, vol.604
, pp. 8-18
-
-
Zhou, C.X.1
Li, Z.X.2
Diao, H.L.3
Yu, Y.K.4
Zhu, W.5
Dai, Y.Y.6
Chen, F.F.7
Yang, J.8
-
69
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and S.J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:1542-1548. http://dx.doi.org/10.1126/science.1083430
-
(2003)
Science.
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|