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Volumn 206, Issue 1, 2014, Pages 29-43

DNA breaks and chromosomal aberrations arise when replication meets base excision repair

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; N METHYLPURINE DNA GLYCOSYLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE) POLYMERASE 1; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

EID: 84904697759     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201312078     Document Type: Article
Times cited : (110)

References (69)
  • 2
    • 0032768327 scopus 로고    scopus 로고
    • Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity
    • Angelis, K.J., M. Dusinská, and A.R. Collins. 1999. Single cell gel electrophoresis: detection of DNA damage at different levels of sensitivity. Electrophoresis. 20:2133-2138. http://dx.doi.org/10.1002/(SICI)1522-2683(19990701)20:10<2133::AID-ELPS2133>3.0.CO;2-Q.
    • (1999) Electrophoresis. , vol.20 , pp. 2133-2138
    • Angelis, K.J.1    Dusinská, M.2    Collins, A.R.3
  • 4
    • 0030740948 scopus 로고    scopus 로고
    • Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway
    • Bennett, R.A.O., D.M. Wilson III, D. Wong, and B. Demple. 1997. Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. Proc. Natl. Acad. Sci. USA. 94:7166-7169. http://dx.doi.org/10.1073/pnas.94.14.7166.
    • (1997) Proc. Natl. Acad. Sci. USA. , vol.94 , pp. 7166-7169
    • Bennett, R.A.O.1    Wilson, D.M.2    Wong, D.3    Demple, B.4
  • 5
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek, D.T. 1990. Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents. Mutat. Res. 231:11-30. http://dx.doi.org/10.1016/0027-5107(90)90173-2.
    • (1990) Mutat. Res. , vol.231 , pp. 11-30
    • Beranek, D.T.1
  • 6
    • 0023025598 scopus 로고
    • Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis
    • Bianchi, V., E. Pontis, and P. Reichard. 1986. Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis. J. Biol. Chem. 261:16037-16042.
    • (1986) J. Biol. Chem. , vol.261 , pp. 16037-16042
    • Bianchi, V.1    Pontis, B.2    Reichard, P.3
  • 7
    • 0037173449 scopus 로고    scopus 로고
    • Intrachanges as part of complex chromosome-type exchange aberrations
    • Boei, J.J.W.A., S. Vermeulen, J. Moser, L.H.F. Mullenders, and A.T. Natarajan. 2002. Intrachanges as part of complex chromosome-type exchange aberrations. Mutat. Res. 504:47-55. http://dx.doi.org/10.1016/S0027- 5107(02)00078-7.
    • (2002) Mutat. Res. , vol.504 , pp. 47-55
    • Boei, J.J.W.A.1    Vermeulen, P.2    Moser, J.3    Mullenders, L.H.F.4    Natarajan, A.T.5
  • 8
    • 44149126949 scopus 로고    scopus 로고
    • The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR
    • Brem, R., M. Fernet, B. Chapot, and J. Hall. 2008. The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR. DNA Repair (Amst.). 7:849-857. http://dx.doi.org/10.1016/j.dnarep.2008.02.002.
    • (2008) DNA Repair (Amst.). , vol.7 , pp. 849-857
    • Brem, R.1    Fernet, M.2    Chapot, B.3    Hall, J.4
  • 9
    • 0041378046 scopus 로고    scopus 로고
    • XRCC1 and DNA strand break repair
    • Caldecott, K.W. 2003. XRCC1 and DNA strand break repair. DNA Repair (Amst.). 2:955-969. http://dx.doi.org/10.1016/S1568-7864(03)00118-6.
    • (2003) DNA Repair (Amst.). , vol.2 , pp. 955-969
    • Caldecott, K.W.1
  • 10
    • 48249095920 scopus 로고    scopus 로고
    • Single-strand break repair and genetic disease
    • Caldecott, K.W. 2008. Single-strand break repair and genetic disease. Nat. Rev. Genet. 9:619-631.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 619-631
    • Caldecott, K.W.1
  • 11
    • 0029957245 scopus 로고    scopus 로고
    • XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro
    • Caldecott, K.W., S. Aoufouchi, P. Johnson, and S. Shall. 1996. XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. Nucleic Acids Res. 24:4387-4394. http://dx.doi.org/10.1093/nar/24.22.4387.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4387-4394
    • Caldecott, K.W.1    Aoufouchi, S.2    Johnson, P.3    Shall, S.4
  • 13
    • 20644453965 scopus 로고    scopus 로고
    • XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair
    • Campalans, A., S. Marsin, Y. Nakabeppu, T.R. O'connor, S. Boiteux, and J.P. Radicella. 2005. XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. DNA Repair (Amst.). 4:826-835. http://dx.doi.org/10.1016/j.dnarep.2005.04.014.
    • (2005) DNA Repair (Amst.). , vol.4 , pp. 826-835
    • Campalans, A.1    Marsin, S.2    Nakabeppu, Y.3    O'connor, T.R.4    Boiteux, S.5    Radicella, J.P.6
  • 14
    • 0023034962 scopus 로고
    • Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line
    • Carrano, A.V., J.L. Minkler, L.E. Dillehay, and L.H. Thompson. 1986. Incorporated bromodeoxyuridine enhances the sister-chromatid exchange and chromosomal aberration frequencies in an EMS-sensitive Chinese hamster cell line. Mutat. Res. 162:233-239. http://dx.doi.org/10.1016/0027-5107(86)90090-4.
    • (1986) Mutat. Res. , vol.162 , pp. 233-239
    • Carrano, A.V.1    Minkler, J.L.2    Dillehay, L.E.3    Thompson, L.H.4
  • 15
    • 0024411112 scopus 로고
    • Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences
    • Ch'ang, L.Y., W.K. Yang, F.E. Myer, and D.M. Yang. 1989. Negative regulatory element associated with potentially functional promoter and enhancer elements in the long terminal repeats of endogenous murine leukemia virus-related proviral sequences. J. Virol. 63:2746-2757.
    • (1989) J. Virol. , vol.63 , pp. 2746-2757
    • Ch'ang, L.Y.1    Yang, W.K.2    Myer, F.E.3    Yang, D.M.4
  • 16
    • 0025949662 scopus 로고
    • Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase
    • Chakravarti, D., G.C. Ibeanu, K. Tano, and S. Mitra. 1991. Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase. J. Biol. Chem. 266:15710-15715.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15710-15715
    • Chakravarti, D.1    Ibeanu, G.C.2    Tano, K.3    Mitra, S.4
  • 17
    • 57149112500 scopus 로고    scopus 로고
    • Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair
    • Chou, W.C., H.C. Wang, F.H. Wong, S.L. Ding, P.E. Wu, S.Y. Shieh, and C.Y. Shen. 2008. Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair. EMBO J. 27:3140-3150. http://dx.doi.org/10.1038/emboj.2008.229.
    • (2008) EMBO J. , vol.27 , pp. 3140-3150
    • Chou, W.C.1    Wang, H.C.2    Wong, F.H.3    Ding, S.L.4    Wu, P.E.5    Shieh, S.Y.6    Shen, C.Y.7
  • 18
    • 0028801762 scopus 로고
    • Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents-a case of imbalanced DNA repair
    • Coquerelle, T., J. Dosch, and B. Kaina. 1995. Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents-a case of imbalanced DNA repair. Mutat. Res. 336:9-17. http://dx.doi.org/10.1016/0921-8777(94)00035-5.
    • (1995) Mutat. Res. , vol.336 , pp. 9-17
    • Coquerelle, T.1    Dosch, J.2    Kaina, B.3
  • 19
    • 84876016461 scopus 로고    scopus 로고
    • Mammalian base excision repair: the forgotten archangel
    • Dianov, G.L., and U. Hübscher. 2013. Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res. 41:3483-3490. http://dx.doi.org/ 10.1093/nar/gkt076.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 3483-3490
    • Dianov, G.L.1    Hübscher, U.2
  • 21
    • 0032570769 scopus 로고    scopus 로고
    • A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome
    • Engelward, B.P., J.M. Allan, A.J. Dreslin, J.D. Kelly, M.M. Wu, B. Gold, and L.D. Samson. 1998. A chemical and genetic approach together define the biological consequences of 3-methyladenine lesions in the mammalian genome. J. Biol. Chem. 273:5412-5418. http://dx.doi.org/10.1074/jbc.273.9.5412.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5412-5418
    • Engelward, B.P.1    Allan, J.M.2    Dreslin, A.J.3    Kelly, J.D.4    Wu, M.M.5    Gold, B.6    Samson, L.D.7
  • 22
    • 84961981834 scopus 로고    scopus 로고
    • Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases
    • Erzberger, J.P., D. Barsky, O.D. Schärer, M.E. Colvin, and D.M. Wilson III. 1998. Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases. Nucleic Acids Res. 26:2771- 2778. http://dx.doi.org/10.1093/nar/26.11.2771.
    • (1998) Nucleic Acids Res. , vol.26
    • Erzberger, J.P.1    Barsky, D.2    Schärer, O.D.3    Colvin, M.E.4    Wilson, D.M.5
  • 23
    • 0014687685 scopus 로고
    • The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis
    • Evans, H.J., and D. Scott. 1969. The induction of chromosome aberrations by nitrogen mustard and its dependence on DNA synthesis. Proc. R. Soc. Lond. B Biol. Sci. 173:491-512. http://dx.doi.org/10.1098/rspb.1969.0073.
    • (1969) Proc. R. Soc. Lond. B Biol. Sci. , vol.173 , pp. 491-512
    • Evans, H.J.1    Scott, D.2
  • 24
    • 0016752877 scopus 로고
    • Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction
    • Frei, J.V., and S. Venitt. 1975. Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction. Mutat. Res. 30:89-96. http://dx.doi.org/10.1016/0027-5107(75)90257-2.
    • (1975) Mutat. Res. , vol.30 , pp. 89-96
    • Frei, J.V.1    Venitt, S.2
  • 25
    • 77956170813 scopus 로고    scopus 로고
    • Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage
    • Groth, P., S. Ausländer, M.M. Majumder, N. Schultz, F. Johansson, E. Petermann, and T. Helleday. 2010. Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage. J. Mol. Biol. 402:70-82. http://dx.doi.org/10.1016/j.jmb.2010.07.010.
    • (2010) J. Mol. Biol. , vol.402 , pp. 70-82
    • Groth, P.1    Ausländer, S.2    Majumder, M.M.3    Schultz, N.4    Johansson, F.5    Petermann, E.6    Helleday, T.7
  • 26
    • 84864933506 scopus 로고    scopus 로고
    • Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation
    • Groth, P., M.L. Orta, I. Elvers, M.M. Majumder, A. Lagerqvist, and T. Helleday. 2012. Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation. Nucleic Acids Res. 40:6585-6594. http://dx.doi.org/10.1093/nar/gks315.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 6585-6594
    • Groth, P.1    Orta, M.L.2    Elvers, I.3    Majumder, M.M.4    Lagerqvist, A.5    Helleday, T.6
  • 27
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu, H., J.D. Marth, P.C. Orban, H. Mossmann, and K. Rajewsky. 1994. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science. 265:103-106. http://dx.doi.org/10.1126/science.8016642.
    • (1994) Science. , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 29
    • 33845330910 scopus 로고    scopus 로고
    • Replisome assembly and the direct restart of stalled replication forks
    • Heller, R.C., and K.J. Marians. 2006. Replisome assembly and the direct restart of stalled replication forks. Nat. Rev. Mol. Cell Biol. 7:932-943. http://dx.doi.org/10.1038/nrm2058.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 932-943
    • Heller, R.C.1    Marians, K.J.2
  • 30
    • 78149425175 scopus 로고    scopus 로고
    • Regulation of homologous recombination in eukaryotes
    • Heyer, W.D., K.T. Ehmsen, and J. Liu. 2010. Regulation of homologous recombination in eukaryotes. Annu. Rev. Genet. 44:113-139. http://dx.doi.org/10.1146/annurev-genet-051710-150955.
    • (2010) Annu. Rev. Genet. , vol.44 , pp. 113-139
    • Heyer, W.D.1    Ehmsen, K.T.2    Liu, J.3
  • 31
    • 38049183244 scopus 로고    scopus 로고
    • XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks
    • Horton, J.K., M. Watson, D.F. Stefanick, D.T. Shaughnessy, J.A. Taylor, and S.H. Wilson. 2008. XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Cell Res. 18:48-63. http://dx.doi.org/10.1038/cr.2008.7.
    • (2008) Cell Res. , vol.18 , pp. 48-63
    • Horton, J.K.1    Watson, M.2    Stefanick, D.F.3    Shaughnessy, D.T.4    Taylor, J.A.5    Wilson, S.H.6
  • 32
    • 0026465075 scopus 로고
    • Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells
    • Ibeanu, G., B. Hartenstein, W.C. Dunn, L.Y. Chang, E. Hofmann, T. Coquerelle, S. Mitra, and B. Kaina. 1992. Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells. Carcinogenesis. 13:1989-1995. http://dx.doi.org/10.1093/carcin/13.11.1989.
    • (1992) Carcinogenesis. , vol.13 , pp. 1989-1995
    • Ibeanu, G.1    Hartenstein, B.2    Dunn, W.C.3    Chang, L.Y.4    Hofmann, E.5    Coquerelle, T.6    Mitra, S.7    Kaina, B.8
  • 33
    • 0032480042 scopus 로고    scopus 로고
    • Critical steps in alkylation-induced aberration formation
    • Kaina, B. 1998. Critical steps in alkylation-induced aberration formation. Mutat. Res. 404:119-124. http://dx.doi.org/10.1016/S0027-5107(98)00103-1.
    • (1998) Mutat. Res. , vol.404 , pp. 119-124
    • Kaina, B.1
  • 34
    • 2642574948 scopus 로고    scopus 로고
    • Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go
    • Kaina, B. 2004. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go. Cytogenet. Genome Res. 104:77-86. http://dx.doi.org/10.1159/000077469.
    • (2004) Cytogenet. Genome Res. , vol.104 , pp. 77-86
    • Kaina, B.1
  • 35
    • 0022363977 scopus 로고
    • Methylation-induced blocks to in vitro DNA replication
    • Larson, K., J. Sahm, R. Shenkar, and B. Strauss. 1985. Methylation-induced blocks to in vitro DNA replication. Mutat. Res. 150:77-84. http://dx.doi.org/10.1016/0027-5107(85)90103-4.
    • (1985) Mutat. Res. , vol.150 , pp. 77-84
    • Larson, K.1    Sahm, J.2    Shenkar, R.3    Strauss, B.4
  • 36
    • 0032694518 scopus 로고    scopus 로고
    • Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents
    • Liu, L., P. Taverna, C.M. Whitacre, S. Chatterjee, and S.L. Gerson. 1999. Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents. Clin. Cancer Res. 5:2908-2917.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2908-2917
    • Liu, L.1    Taverna, P.2    Whitacre, C.M.3    Chatterjee, S.4    Gerson, S.L.5
  • 37
    • 77953166592 scopus 로고    scopus 로고
    • gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization
    • Löbrich, M., A. Shibata, A. Beucher, A. Fisher, M. Ensminger, A.A. Goodarzi, O. Barton, and P.A. Jeggo. 2010. gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle. 9:662-669. http://dx.doi.org/10.4161/cc.9.4.10764.
    • (2010) Cell Cycle. , vol.9 , pp. 662-669
    • Löbrich, M.1    Shibata, A.2    Beucher, A.3    Fisher, A.4    Ensminger, M.5    Goodarzi, A.A.6    Barton, O.7    Jeggo, P.A.8
  • 38
    • 79955635887 scopus 로고    scopus 로고
    • Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease
    • Ma, W.J., J.W. Westmoreland, D.A. Gordenin, and M.A. Resnick. 2011. Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease. PLoS Genet. 7:e1002059. http://dx.doi.org/10.1371/journal.pgen.1002059.
    • (2011) PLoS Genet. , vol.7
    • Ma, W.J.1    Westmoreland, J.W.2    Gordenin, D.A.3    Resnick, M.A.4
  • 39
    • 0031844311 scopus 로고    scopus 로고
    • XRCC1 is specifically associated with poly(ADPribose) polymerase and negatively regulates its activity following DNA damage
    • Masson, M., C. Niedergang, V. Schreiber, S. Muller, J. Menissier-de Murcia, and G. de Murcia. 1998. XRCC1 is specifically associated with poly(ADPribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol. 18:3563-3571.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3563-3571
    • Masson, M.1    Niedergang, C.2    Schreiber, V.3    Muller, S.4    Menissier-de Murcia, J.5    de Murcia, G.6
  • 40
    • 77957168933 scopus 로고    scopus 로고
    • Eukaryotic DNA replication origins: many choices for appropriate answers
    • Méchali, M. 2010. Eukaryotic DNA replication origins: many choices for appropriate answers. Nat. Rev. Mol. Cell Biol. 11:728-738. http://dx.doi.org/10.1038/nrm2976.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 728-738
    • Méchali, M.1
  • 42
    • 0021592929 scopus 로고
    • Molecular mechanisms involved in the production of chromosomal aberrations III. Restriction endonucleases
    • Natarajan, A.T., and G. Obe. 1984. Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases. Chromosoma. 90:120-127. http://dx.doi.org/10.1007/BF00292448.
    • (1984) Chromosoma , vol.90 , pp. 120-127
    • Natarajan, A.T.1    Obe, G.2
  • 44
    • 0022259763 scopus 로고
    • Induction of sister-chromatid exchanges by restriction endonucleases
    • Natarajan, A.T., L.H.F. Mullenders, M. Meijers, and U. Mukherjee. 1985. Induction of sister-chromatid exchanges by restriction endonucleases. Mutat. Res. 144:33-39. http://dx.doi.org/10.1016/0165-7992(85)90121-6.
    • (1985) Mutat. Res. , vol.144 , pp. 33-39
    • Natarajan, A.T.1    Mullenders, L.H.F.2    Meijers, M.3    Mukherjee, U.4
  • 45
    • 34548387438 scopus 로고    scopus 로고
    • Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique
    • Nazarkina, ZhK., S.N. Khodyreva, S. Marsin, J.P. Radicella, and O.I. Lavrik. 2007. Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique. Biochemistry Mosc. 72:878-886. http://dx.doi.org/10.1134/S000629790708010X.
    • (2007) Biochemistry Mosc. , vol.72 , pp. 878-886
    • Nazarkina, Z.K.1    Khodyreva, S.N.2    Marsin, S.3    Radicella, J.P.4    Lavrik, O.I.5
  • 46
    • 77957293431 scopus 로고    scopus 로고
    • Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate
    • Nikolova, T., M. Ensminger, M. Löbrich, and B. Kaina. 2010. Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate. DNA Repair (Amst.). 9:1050-1063. http://dx.doi.org/10.1016/j.dnarep.2010.07.005.
    • (2010) DNA Repair (Amst.). , vol.9 , pp. 1050-1063
    • Nikolova, T.1    Ensminger, M.2    Löbrich, M.3    Kaina, B.4
  • 47
    • 1642411206 scopus 로고    scopus 로고
    • Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase
    • O'Brien, P.J., and T. Ellenberger. 2004. Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase. J. Biol. Chem. 279:9750- 9757. http://dx.doi.org/10.1074/jbc.M312232200.
    • (2004) J. Biol. Chem. , vol.279
    • O'Brien, P.J.1    Ellenberger, T.2
  • 48
    • 0345073699 scopus 로고    scopus 로고
    • A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
    • O'Driscoll, M., V.L. Ruiz-Perez, C.G. Woods, P.A. Jeggo, and J.A. Goodship. 2003. A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat. Genet. 33:497-501. http://dx.doi.org/10.1038/ng1129.
    • (2003) Nat. Genet. , vol.33 , pp. 497-501
    • O'Driscoll, M.1    Ruiz-Perez, V.L.2    Woods, C.G.3    Jeggo, P.A.4    Goodship, J.A.5
  • 49
    • 84876730678 scopus 로고    scopus 로고
    • Co-ordination of base excision repair and genome stability
    • Parsons, J.L., and G.L. Dianov. 2013. Co-ordination of base excision repair and genome stability. DNA Repair (Amst.). 12:326-333. http://dx.doi.org/10.1016/j.dnarep.2013.02.001.
    • (2013) DNA Repair (Amst.). , vol.12 , pp. 326-333
    • Parsons, J.L.1    Dianov, G.L.2
  • 50
    • 13744258586 scopus 로고    scopus 로고
    • The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells
    • Pascucci, B., M.T. Russo, M. Crescenzi, M. Bignami, and E. Dogliotti. 2005. The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells. Nucleic Acids Res. 33:280-288. http://dx.doi.org/10.1093/nar/gki168.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 280-288
    • Pascucci, B.1    Russo, M.T.2    Crescenzi, M.3    Bignami, M.4    Dogliotti, E.5
  • 51
    • 76849109722 scopus 로고    scopus 로고
    • Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair
    • Petermann, E., M.L. Orta, N. Issaeva, N. Schultz, and T. Helleday. 2010. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol. Cell. 37:492-502. http://dx.doi.org/10.1016/j.molcel.2010.01.021.
    • (2010) Mol. Cell. , vol.37 , pp. 492-502
    • Petermann, E.1    Orta, M.L.2    Issaeva, N.3    Schultz, N.4    Helleday, T.5
  • 52
    • 0017354552 scopus 로고
    • Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster
    • Pimpinelli, S., D. Pignone, G. Santini, M. Gatti, and G. Olivieri. 1977. Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster. Genetics. 85:249-257.
    • (1977) Genetics. , vol.85 , pp. 249-257
    • Pimpinelli, S.1    Pignone, D.2    Santini, G.3    Gatti, M.4    Olivieri, G.5
  • 53
    • 79953708229 scopus 로고    scopus 로고
    • CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
    • Quennet, V., A. Beucher, O. Barton, S. Takeda, and M. Löbrich. 2011. CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res. 39:2144-2152. http://dx.doi.org/10.1093/nar/gkq1175.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 2144-2152
    • Quennet, V.1    Beucher, A.2    Barton, O.3    Takeda, S.4    Löbrich, M.5
  • 54
    • 84859789451 scopus 로고    scopus 로고
    • Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors
    • Rai, G., V.N. Vyjayanti, D. Dorjsuren, A. Simeonov, A. Jadhav, D.M. Wilson III, and D.J. Maloney. 2012. Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors. J. Med. Chem. 55:3101-3112. http://dx.doi.org/10.1021/jm201537d.
    • (2012) J. Med. Chem. , vol.55 , pp. 3101-3112
    • Rai, G.1    Vyjayanti, V.N.2    Dorjsuren, D.3    Simeonov, A.4    Jadhav, A.5    Wilson, D.M.6    Maloney, D.J.7
  • 55
    • 0035898405 scopus 로고    scopus 로고
    • Characterization of homologous recombination induced by replication inhibition in mammalian cells
    • Saintigny, Y., F. Delacôte, G. Varès, F. Petitot, S. Lambert, D. Averbeck, and B.S. Lopez. 2001. Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J. 20:3861-3870. http://dx.doi.org/10.1093/emboj/20.14.3861.
    • (2001) EMBO J. , vol.20 , pp. 3861-3870
    • Saintigny, Y.1    Delacôte, F.2    Varès, G.3    Petitot, F.4    Lambert, S.5    Averbeck, D.6    Lopez, B.S.7
  • 56
    • 23344444636 scopus 로고    scopus 로고
    • Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
    • Saleh-Gohari, N., H.E. Bryant, N. Schultz, K.M. Parker, T.N. Cassel, and T. Helleday. 2005. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol. Cell. Biol. 25:7158-7169. http://dx.doi.org/10.1128/MCB.25.16.7158-7169.2005.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7158-7169
    • Saleh-Gohari, N.1    Bryant, H.E.2    Schultz, N.3    Parker, K.M.4    Cassel, T.N.5    Helleday, T.6
  • 57
    • 0032519294 scopus 로고    scopus 로고
    • Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair
    • Shen, M.R., M.Z. Zdzienicka, H. Mohrenweiser, L.H. Thompson, and M.P. Thelen. 1998. Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair. Nucleic Acids Res. 26:1032-1037. http://dx.doi.org/10.1093/nar/26.4.1032.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1032-1037
    • Shen, M.R.1    Zdzienicka, M.Z.2    Mohrenweiser, H.3    Thompson, L.H.4    Thelen, M.P.5
  • 60
    • 0034124053 scopus 로고    scopus 로고
    • Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5?-phosphorylated DNA double-strand breaks by replication runoff
    • Strumberg, D., A.A. Pilon, M. Smith, R. Hickey, L. Malkas, and Y. Pommier. 2000. Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5?-phosphorylated DNA double-strand breaks by replication runoff. Mol. Cell. Biol. 20:3977-3987. http://dx.doi.org/10.1128/MCB.20.11.3977-3987.2000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3977-3987
    • Strumberg, D.1    Pilon, A.A.2    Smith, M.3    Hickey, R.4    Malkas, L.5    Pommier, Y.6
  • 61
    • 0035837590 scopus 로고    scopus 로고
    • Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells
    • Taverna, P., L. Liu, H.S. Hwang, A.J. Hanson, T.J. Kinsella, and S.L. Gerson. 2001. Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells. Mutat. Res. 485:269-281. http://dx.doi.org/10.1016/S0921-8777(01)00076-3.
    • (2001) Mutat. Res. , vol.485 , pp. 269-281
    • Taverna, P.1    Liu, L.2    Hwang, H.S.3    Hanson, A.J.4    Kinsella, T.J.5    Gerson, S.L.6
  • 62
    • 0019956767 scopus 로고
    • A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange
    • Thompson, L.H., K.W. Brookman, L.E. Dillehay, A.V. Carrano, J.A. Mazrimas, C.L. Mooney, and J.L. Minkler. 1982. A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange. Mutat. Res. 95:427-440. http://dx.doi.org/10.1016/0027-5107(82)90276-7.
    • (1982) Mutat. Res. , vol.95 , pp. 427-440
    • Thompson, L.H.1    Brookman, K.W.2    Dillehay, L.E.3    Carrano, A.V.4    Mazrimas, J.A.5    Mooney, C.L.6    Minkler, J.L.7
  • 63
    • 0032102896 scopus 로고    scopus 로고
    • DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines
    • Trucco, C., F.J. Oliver, G. de Murcia, and J. Ménissier-de Murcia. 1998. DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines. Nucleic Acids Res. 26:2644-2649. http://dx.doi.org/10.1093/nar/26.11.2644.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2644-2649
    • Trucco, C.1    Oliver, F.J.2    de Murcia, G.3    Ménissier-de Murcia, J.4
  • 64
    • 0035890069 scopus 로고    scopus 로고
    • XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
    • Vidal, A.E., S. Boiteux, I.D. Hickson, and J.P. Radicella. 2001. XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. EMBO J. 20:6530-6539. http://dx.doi.org/10.1093/emboj/20.22.6530.
    • (2001) EMBO J. , vol.20 , pp. 6530-6539
    • Vidal, A.E.1    Boiteux, S.2    Hickson, I.D.3    Radicella, J.P.4
  • 65
    • 0035846899 scopus 로고    scopus 로고
    • XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
    • Whitehouse, C.J., R.M. Taylor, A. Thistlethwaite, H. Zhang, F. Karimi-Busheri, D.D. Lasko, M. Weinfeld, and K.W. Caldecott. 2001. XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell. 104:107-117. http://dx.doi.org/10.1016/S0092-8674(01)00195-7.
    • (2001) Cell. , vol.104 , pp. 107-117
    • Whitehouse, C.J.1    Taylor, R.M.2    Thistlethwaite, A.3    Zhang, H.4    Karimi-Busheri, F.5    Lasko, D.D.6    Weinfeld, M.7    Caldecott, K.W.8
  • 66
    • 33845726097 scopus 로고    scopus 로고
    • Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks
    • Wyatt, M.D., and D.L. Pittman. 2006. Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. Chem. Res. Toxicol. 19:1580-1594. http://dx.doi.org/10.1021/tx060164e.
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 1580-1594
    • Wyatt, M.D.1    Pittman, D.L.2
  • 67
    • 0026651211 scopus 로고
    • A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges
    • Zdzienicka, M.Z., G.P. van der Schans, A.T. Natarajan, L.H. Thompson, I. Neuteboom, and J.W.I.M. Simons. 1992. A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges. Mutagenesis. 7:265-269. http://dx.doi.org/10.1093/mutage/7.4.265.
    • (1992) Mutagenesis. , vol.7 , pp. 265-269
    • Zdzienicka, M.Z.1    van der Schans, G.P.2    Natarajan, A.T.3    Thompson, L.H.4    Neuteboom, I.5    Simons, J.W.I.M.6
  • 69
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou, L., and S.J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:1542-1548. http://dx.doi.org/10.1126/science.1083430
    • (2003) Science. , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2


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