Dissecting the Broad Substrate Specificity of Human 3-Methyladenine-DNA Glycosylase

Journal of Biological Chemistry

Volumn 279, Issue 11, 2004, Pages 9750-9757

  O'Brien, Patrick J ^a   Ellenberger, Tom ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; CHEMICAL BONDS; DNA; ENZYMES; GENES; HYDROLYSIS;

BASE FLIPPING; LESIONS;

BIOCHEMISTRY;

2 AMINOPURINE; 3 METHYLADENINE; 3 METHYLADENINE DEOXYRIBONUCLEIC ACID GLYCOSYLASE; 7 METHYLGUANINE; ADENINE; DNA BASE; DNA GLYCOSYLTRANSFERASE; GUANINE; HYPOXANTHINE; NUCLEIC ACID BASE; OLIGONUCLEOTIDE; PURINE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; BASE PAIRING; CATALYSIS; CONTRAST ENHANCEMENT; DNA DAMAGE; DNA MODIFICATION; DNA REPLICATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDROLYSIS; PRIORITY JOURNAL;

ADENINE; BASE PAIRING; CATALYSIS; DNA; DNA GLYCOSYLASES; GUANINE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; OLIGONUCLEOTIDES; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 1642411206     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312232200     Document Type: Article

References (44)

1. Lindahl, T. (1993) Nature 362, 709-715
2. Gallagher, P. E., and Brent, T. P. (1982) Biochem. J. 21, 6404-6409
3. Singer, B., Antoccia, A., Basu, A. K., Dosanjh, M. K., Fraenkel-Conrat, H., Gallagher, P. E., Kusmierek, J. T., Qiu, Z. H., and Rydberg, B. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9386-9390
4. O'Connor, T. R. (1993) Nucleic Acids Res. 21, 5561-5569
5. Engelward, B., Weeda, G., Wyatt, M. D., Broekhof, J., Wit, J. D., Donker, I., Allan, J., Gold, B., Hoeijmakers, J., and Samson, L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 13087-13092
6. Hang, B., Singer, B., Margison, G. P., and Elder, R. H. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12869-12874
7. Miao, F., Bouziane, M., and O'Connor, T. R. (1998) Nucleic Acids Res. 26, 4034-4041
8. Saparbaev, M., and Laval, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5873-5877
9. Duncan, B. K. (1981) Enzymes 14, 565-586
10. Lau, A. Y., Wyatt, M. D., Glassner, B. J., Samson, L. D., and Ellenberger, T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 13573-13578
11. Biswas, T., Clos, L. J., III, SantaLucia, J., Jr., Mitra, S., and Roy, R. (2002) J. Mol. Biol. 320, 503-513
12. O'Brien, P. J., and Ellenberger, T. (2003) Biochemistry 42, 12418-12429
13. Berdal, K. G., Johansen, R. F., and Seeberg, E. (1998) EMBO J. 17, 363-367
14. Lindahl, T., and Nyberg, B. (1972) Biochemistry 11, 3610-3618
15. Roberts, R. J., and Cheng, X. (1998) Annu. Rev. Biochem. 67, 181-198
16. Connor, E. E., and Wyatt, M. D. (2002) Chem. Biol. 9, 1033-1041
17. Peyret, N., Seneviratne, P. A., Allawi, H. T., and SantaLucia, J., Jr. (1999) Biochemistry 38, 3468-3477
18. Kartalou, M., Samson, L. D., and Essigmann, J. M. (2000) Biochemistry 39, 8032-8038
19. Leonard, G. A., McAuley-Hecht, K. E., Gibson, N. J., Brown, T., Watson, W. P., and Hunter, W. N. (1994) Biochemistry 33, 4755-4761
20. Martin, F. H., Castro, M. M., Aboul-ela, F., and Tinoco, I. (1985) Nucleic Acids Res. 13, 8927-8938
21. Law, S. M., Eritja, R., Goodman, M. F., and Breslauer, K. J. (1996) Biochemistry 35, 12329-12337
22. Ikuta, S., Eritja, R., Kaplan, B. E., and Itakura, K. (1987) Biochemistry 26, 5646-5650
23. Hendler, S., Furer, E., and Srinivasan, P. R. (1970) Biochemistry 9, 4141-4153
24. Osborne, M. R., and Phillips, D. H. (2000) Chem. Res. Toxicol. 13, 257-261
25. Oivanen, M., Hovinen, J., Lehikoinen, P., and Lonnberg, H. (1993) Trends Org. Chem. 4, 397-412
26. Radzicka, A., and Wolfenden, R. (1995) Science 267, 90-93
27. O'Connor, T. R., and Laval, J. (1991) Biochem. Biophys. Res. Commun. 176, 1170-1177
28. Karran, P., and Lindahl, T. (1980) Biochemistry 19, 6005-6011
29. Wood, S., Ubasawa, A., Martin, D., and Jiricny, J. (1986) Nucleic Acids Res. 14, 6591-6602
30. Stivers, J. T., and Drohat, A. C. (2001) Arch. Biochem. Biophys. 396, 1-9
31. Abner, C., Lau, A. Y., Ellenberger, T., and Bloom, L. B. (2001) J. Biol. Chem. 276, 13379-13387
32. Wong, I., Lundquist, A. J., Bernards, A. S., and Mosbaugh, D. W. (2002) J. Biol. Chem. 277, 19424-19432
33. Allan, B. W., Reich, N. O., and Beechem, J. M. (1999) Biochemistry 38, 5308-5314
34. Jiang, Y. L., and Stivers, J. T. (2002) Biochemistry 41, 11236-11247
35. McKay, G., Thompson, P., and Wright, G. (1994) Biochemistry 33, 6936-6944
36. Radika, K., and Northrop, D. (1984) Biochemistry 23, 5118-5122
37. Salinas, A., and Wong, M. (1999) Curr. Med. Chem. 6, 279-309
38. Gonzalez, F. (1992) Trends Pharm. Sci. 13, 346-352
39. Lienhard, G. E. (1973) Science 180, 149-154
40. Jencks, W. (1975) Adv. Enzymol. Relat. Areas Mol. Biol. 43, 219-410
41. Branum, M. E., Reardon, J. T., and Sancar, A. (2001) J. Biol. Chem. 276, 25421-25426
42. Hanawalt, P. C. (2002) Oncogene 21, 8949-8956
43. Bruskov, V., Malakhova, L., Masalimov, Z., and Chernikov, A. (2002) Nucleic Acids Res. 30, 1354-1363
44. Aamodt, R. M., Falnes, P. Ø., Johansen, R. F., Seeberg, E., and Bjøras, M. (2004) J. Biol. Chem., in press