Melatonin reduced microglial activation and alleviated neuroinflammation induced neuron degeneration in experimental traumatic brain injury: Possible involvement of mTOR pathway

Neurochemistry International

Volumn 76, Issue , 2014, Pages 23-31

  Ding, Ke ^a   Wang, Handong ^a   Xu, Jianguo ^a   Lu, Xinyu ^a   Zhang, Li ^a   Zhu, Lin ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Inflammation; Mammalian target of rapamycin; Melatonin; Microglia activation; Traumatic brain injury

Indexed keywords

INTERLEUKIN 1BETA; MAMMALIAN TARGET OF RAPAMYCIN; MELATONIN; PROTEIN S6; S6 KINASE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN CONTUSION; BRAIN EDEMA; BRAIN WATER; CELL ACTIVATION; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; DRY WEIGHT; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; MALE; MICROGLIA; MOUSE; NERVE CELL; NERVE CELL DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NISSL STAINING; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEPHOSPHORYLATION; SHAM PROCEDURE; TRAUMATIC BRAIN INJURY; WATER CONTENT; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; BRAIN INJURY; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN INJURIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MELATONIN; MICE; MICE, INBRED ICR; MICROGLIA; NEURONS; TOR SERINE-THREONINE KINASES;

EID: 84904564277     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2014.06.015     Document Type: Article

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