BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic brain injury therapy

Biomaterials

Volumn 33, Issue 11, 2012, Pages 3119-3126

  Shi, Wei ^a   Nie, Dekang ^a   Jin, Guohua ^a   Chen, Weiwei ^a,b   Xia, Liang ^a   Wu, Xiujie ^a   Su, Xing ^a   Xu, Xide ^a   Ni, Lanchun ^a   Zhang, Xianan ^a   Zhang, Xinhua ^a   Chen, Jian ^a  

^a NANTONG UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Brain derived neurotrophic factor; Chitosan scaffold; Co culture; Genipin; Human umbilical cord mesenchymal stem cells; Neural stem cell

Indexed keywords

BRAIN-DERIVED NEUROTROPHIC FACTORS; CHITOSAN SCAFFOLD; COCULTURE; GENIPIN; HUMAN UMBILICAL CORD; NEURAL STEM CELL;

BRAIN; CELL CULTURE; CHITOSAN; FLOWCHARTING; STEM CELLS;

SCAFFOLDS (BIOLOGY);

BRAIN DERIVED NEUROTROPHIC FACTOR; CHITOSAN; CHOLECYSTOKININ OCTAPEPTIDE; GENIPIN; TRYPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; BONE MARROW CELL; CELL ADHESION; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; FREEZE DRYING; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL TRANSPLANTATION; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROPROTECTION; NONHUMAN; POROSITY; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CHITOSAN; CORD BLOOD STEM CELL TRANSPLANTATION; DELAYED-ACTION PREPARATIONS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MESENCHYMAL STEM CELL TRANSPLANTATION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE SCAFFOLDS;

EID: 84862799581     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.01.009     Document Type: Article

References (34)

1. Shukla D., Devi B.I. Mild traumatic brain injuries in adults. JNeurosci Rural Pract 2010, 1(2):82-88.
2. Keilhoff G., Stang F., Goihl A., Wolf G., Fansa H. Transdifferentiated mesenchymal stem cells as alternative therapy in supporting nerve regeneration and myelination. Cell Mol Neurobiol 2006, 26(7-8):1235-1252.
3. Lim J.Y., Jeong C.H., Jun J.A., Kim S.M., Ryu C.H., Hou Y., et al. Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral ischemia. Stem Cell Res Ther 2011, 2(5):38.
4. Kim J.Y., Jeon H.B., Yang Y.S., Oh W., Chang J.W. Application of human umbilical cord blood-derived mesenchymal stem cells in disease models. World J Stem Cells 2010, 2(2):34-38.
5. Lee J.H., Chung W.H., Kang E.H., Chung D.J., Choi C.B., Chang H.S., et al. Schwann cell-like remyelination following transplantation of human umbilical cord blood (hUCB)-derived mesenchymal stem cells in dogs with acute spinal cord injury. JNeurol Sci 2011, 300(1-2):86-96.
6. Wang H.W., Lin L.M., He H.Y., You F., Li W.Z., Huang T.H., et al. Human umbilical cord mesenchymal stem cells derived from wharton's jelly differentiate into insulin-producing cells invitro. Chin Med J (Engl) 2011, 124(10):1534-1539.
7. Zhao Z., Chen Z., Zhao X., Pan F., Cai M., Wang T., et al. Sphingosine-1-phosphate promotes the differentiation of human umbilical cord mesenchymal stem cells into cardiomyocytes under the designated culturing conditions. JBiomed Sci 2011, 18:37.
8. Zhang H.T., Chen H., Zhao H., Dai Y.W., Xu R.X. Neural stem cells differentiation ability of human umbilical cord mesenchymal stromal cells is not altered by cryopreservation. Neurosci Lett 2011, 487(1):118-122.
9. Yang Y., Zhao W., He J., Zhao Y., Ding F., Gu X. Nerve conduits based on immobilization of nerve growth factor onto modified chitosan by using genipin as a crosslinking agent. Eur J Pharm Biopharm 2011, 79(3):519-525.
10. Wang G., Ao Q., Gong K., Wang A., Zheng L., Gong Y., et al. The effect of topology of chitosan biomaterials on the differentiation and proliferation of neural stem cells. Acta Biomater 2011, 6(9):3630-3639.
11. Dokmeci M.R., Khademhosseini A. Preface to special topic: microfluidics in cell biology and tissue engineering. Biomicrofluidics 2011, 5(2):22101.
12. Cheng M., Cao W., Gao Y., Gong Y., Zhao N., Zhang X. Studies on nerve cell affinity of biodegradable modified chitosan films. JBiomater Sci Polym Ed 2003, 14(10):1155-1167.
13. Fukuda J., Khademhosseini A., Yeo Y., Yang X., Yeh J., Eng G., et al. Micromolding of photocrosslinkable chitosan hydrogel for spheroid microarray and co-cultures. Biomaterials 2006, 27(30):5259-5267.
14. Li Z., Ramay H.R., Hauch K.D., Xiao D., Zhang M. Chitosan-alginate hybrid scaffolds for bone tissue engineering. Biomaterials 2005, 26(18):3919-3928.
15. Itoh S., Yamaguchi I., Suzuki M., Ichinose S., Takakuda K., Kobayashi H., et al. Hydroxyapatite-coated tendon chitosan tubes with adsorbed laminin peptides facilitate nerve regeneration invivo. Brain Res 2003, 993(1-2):111-123.
16. Itoh S., Suzuki M., Yamaguchi I., Takakuda K., Kobayashi H., Shinomiya K., et al. Development of a nerve scaffold using a tendon chitosan tube. Artif Organs 2003, 27(12):1079-1088.
17. Li X., Yang Z., Zhang A., Wang T., Chen W. Repair of thoracic spinal cord injury by chitosan tube implantation. Biomaterials 2009, 30(6):1121-1132.
18. Lenas P., Moos M., Luyten F.P. Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. part I: from three-dimensional cell growth to biomimetics of invivo development. Tissue Eng Part B Rev 2009, 15(4):381-394.
19. Vindigni V., Cortivo R., Iacobellis L., Abatangelo G., Zavan B. Hyaluronan benzyl ester as a scaffold for tissue engineering. Int J Mol Sci 2009, 10(7):2972-2985.
20. Jiang Q.S., Liang Z.L., Wu M.J., Feng L., Liu L.L., Zhang J.J. Reduced brain-derived neurotrophic factor expression in cortex and hippocampus involved in the learning and memory deficit in molarless SAMP8 mice. Chin Med J (Engl) 2011, 124(10):1540-1544.
21. Zhang S., Liu X.Z., Liu Z.L., Wang Y.M., Hu Q.L., Ma T.Z., et al. Stem cells modified by brain-derived neurotrophic factor to promote stem cells differentiation into neurons and enhance neuromotor function after brain injury. Chin J Traumatol 2009, 12(4):195-199.
22. Sung H.W., Huang R.N., Huang L.L., Tsai C.C. Invitro evaluation of cytotoxicity of a naturally occurring cross-linking reagent for biological tissue fixation. JBiomater Sci Polym Ed 1999, 10(1):63-78.
23. Mi F.L., Tan Y.C., Liang H.F., Sung H.W. Invivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials 2002, 23(1):181-191.
24. Hsu Y.Y., Gresser J.D., Trantolo D.J., Lyons C.M., Gangadharam P.R., Wise D.L. Effect of polymer foam morphology and density on kinetics of invitro controlled release of isoniazid from compressed foam matrices. JBiomed Mater Res 1997, 35(1):107-116.
25. Li H., Jin G., Qin J., Tian M., Shi J., Yang W., et al. Characterization and identification of Sox2+ radial glia cells derived from rat embryonic cerebral cortex. Histochem Cell Biol 2011, 136(5):515-526.
26. O'Connor W.T., Smyth A., Gilchrist M.D. Animal models of traumatic brain injury: a critical evaluation. Pharmacol Ther 2011, 130(2):106-113.
27. Shojo H., Kaneko Y., Mabuchi T., Kibayashi K., Adachi N., Borlongan C.V. Genetic and histologic evidence implicates role of inflammation in traumatic brain injury-induced apoptosis in the rat cerebral cortex following moderate fluid percussion injury. Neuroscience 2010, 171(4):1273-1282.
28. Mitchell K.E., Weiss M.L., Mitchell B.M., Martin P., Davis D., Morales L., et al. Matrix cells from wharton's jelly form neurons and glia. Stem Cells 2003, 21(1):50-60.
29. Yan X.H., Huang R.B. Differentiation of human umbilical cord blood mesenchymal stem cells toward neurons induced by baicalin invitro. Zhonghua Er Ke Za Zhi 2006, 44(4):214-219.
30. Troyer D.L., Weiss M.L. Wharton's jelly-derived cells are a primitive stromal cell population. Stem Cells 2008, 26(3):591-599.
31. Karahuseyinoglu S., Cinar O., Kilic E., Kara F., Akay G.G., Demiralp D.O., et al. Biology of stem cells in human umbilical cord stroma: in situ and invitro surveys. Stem Cells 2007, 25(2):319-331.
32. Weiss M.L., Anderson C., Medicetty S., Seshareddy K.B., Weiss R.J., VanderWerff I., et al. Immune properties of human umbilical cord wharton's jelly-derived cells. Stem Cells 2008, 26(11):2865-2874.
33. Sanchez-Ramos J.R., Song S., Kamath S.G., Zigova T., Willing A., Cardozo-Pelaez F., et al. Expression of neural markers in human umbilical cord blood. Exp Neurol 2001, 171(1):109-115.
34. Lu D., Sanberg P.R., Mahmood A., Li Y., Wang L., Sanchez-Ramos J., et al. Intravenous administration of umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury. Cell Transplant 2002, 11(3):275-281.