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Volumn 37, Issue 1, 2012, Pages 69-83

Neural stem cells over-expressing brain-derived neurotrophic factor (BDNF) stimulate synaptic protein expression and promote functional recovery following transplantation in rat model of traumatic brain injury

Author keywords

Brain derived neurotrophic factor; Neural stem cell; Synaptogenesis; Transplantation; Traumatic brain injury

Indexed keywords

BETA III TUBULIN; BETA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; NESTIN; NEUROMODULIN; PROTEIN; SHANK2 PROTEIN; SYP PROTEIN; UNCLASSIFIED DRUG;

EID: 84856295053     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0584-1     Document Type: Article
Times cited : (89)

References (47)
  • 1
    • 34548361737 scopus 로고    scopus 로고
    • Return to work following traumatic brain injury: Trends and challenges
    • DOI 10.1080/09638280701315011, PII 779597521, Return to Work (RTW)
    • Shames J, Treger I, Ring H et al (2007) Return to work following traumatic brain injury: trends and challenges. Disabil Rehabil 29:1387-1395 (Pubitemid 47342885)
    • (2007) Disability and Rehabilitation , vol.29 , Issue.17 , pp. 1387-1395
    • Shames, J.1    Treger, I.2    Ring, H.3    Giaquinto, S.4
  • 2
    • 0028214265 scopus 로고
    • Functional recovery in hemiparkinsonian primates transplanted with polymer-encapsulated PC12 cells
    • DOI 10.1006/exnr.1994.1053
    • Aebischer P, Goddard M, Signore AP et al (1994) Functional recovery in hemiparkinsonian primates transplanted with polymerencapsulated PC12 cells. Exp Neurol 126:151-158 (Pubitemid 24182036)
    • (1994) Experimental Neurology , vol.126 , Issue.2 , pp. 151-158
    • Aebischer, P.1    Goddard, M.2    Signore, A.P.3    Timpson, R.L.4
  • 3
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • DOI 10.1126/science.287.5457.1433
    • Gage FH (2000) Mammalian neural stem cells. Science 287:1433-1438 (Pubitemid 30127128)
    • (2000) Science , vol.287 , Issue.5457 , pp. 1433-1438
    • Gage, F.H.1
  • 4
    • 3142521479 scopus 로고    scopus 로고
    • Stem cell therapy for human neurodegenerative disorders - How to make it work
    • DOI 10.1038/nm1064
    • Lindvall O, Kokaia Z, Martinez-Serrano A (2004) Stem cell therapy for human neurodegenerative disorders: how to make it work? Nat Med 10:42-50 (Pubitemid 38901866)
    • (2004) Nature Medicine , vol.10 , Issue.SUPPL.
    • Lindvall, O.1    Kokaia, Z.2    Martinez-Serrano, A.3
  • 5
    • 0033916716 scopus 로고    scopus 로고
    • Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice
    • Benninger Y, Marino S, Hardegger R et al (2000) Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice. Brain Pathol 10:330-341 (Pubitemid 30431286)
    • (2000) Brain Pathology , vol.10 , Issue.3 , pp. 330-341
    • Benninger, Y.1    Marino, S.2    Hardegger, R.3    Weissmann, C.4    Aguzzi, A.5    Brandner, S.6
  • 6
    • 64849085627 scopus 로고    scopus 로고
    • Subacute neural stem cell therapy for traumatic brain injury
    • 18694578 1:CAS:528:DC%2BD1MXltVGjsrs%3D 10.1016/j.jss.2008.03.037
    • Harting MT, Sloan LE, Jimenez F et al (2009) Subacute neural stem cell therapy for traumatic brain injury. J Surg Res 153:188-194
    • (2009) J Surg Res , vol.153 , pp. 188-194
    • Harting, M.T.1    Sloan, L.E.2    Jimenez, F.3
  • 8
    • 0036715222 scopus 로고    scopus 로고
    • Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
    • DOI 10.1161/01.STR.0000027693.50675.C5
    • Modo M, Stroemer P, Tang E et al (2002) Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. Stroke 33:2270-2278 (Pubitemid 35014642)
    • (2002) Stroke , vol.33 , Issue.9 , pp. 2270-2278
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Patel, S.4    Hodges, H.5
  • 9
    • 70349601665 scopus 로고    scopus 로고
    • Cografted Wharton's jelly cells-derived neurospheres and BDNF promote functional recovery after rat spinal cord transection
    • 19462232 1:CAS:528:DC%2BD1MXmt1Sktrw%3D 10.1007/s11064-009-9992-x
    • Zhang L, Zhang HT, Hong SQ et al (2009) Cografted Wharton's jelly cells-derived neurospheres and BDNF promote functional recovery after rat spinal cord transection. Neurochem Res 34:2030-2039
    • (2009) Neurochem Res , vol.34 , pp. 2030-2039
    • Zhang, L.1    Zhang, H.T.2    Hong, S.Q.3
  • 10
    • 41849087669 scopus 로고    scopus 로고
    • BDNF increases homotypic olivocerebellar reinnervation and associated fine motor and cognitive skill
    • DOI 10.1093/brain/awn024
    • Willson ML, McElnea C, Mariani J et al (2008) BDNF increases homotypic olivocerebellar reinnervation and associated fine motor and cognitive skill. Brain 131:1099-1112 (Pubitemid 351499425)
    • (2008) Brain , vol.131 , Issue.4 , pp. 1099-1112
    • Willson, M.L.1    McElnea, C.2    Mariani, J.3    Lohof, A.M.4    Sherrard, R.M.5
  • 11
    • 77955981342 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: Role in pathogenesis and treatment
    • 20679891 1:CAS:528:DC%2BC3cXhtVCntLfN 10.1097/FBP.0b013e32833d8bc9
    • Kaplan GB, Vasterling JJ, Vedak PC (2010) Brain-derived neurotrophic factor in traumatic brain injury, post-traumatic stress disorder, and their comorbid conditions: role in pathogenesis and treatment. Behav Pharmacol 21:427-437
    • (2010) Behav Pharmacol , vol.21 , pp. 427-437
    • Kaplan, G.B.1    Vasterling, J.J.2    Vedak, P.C.3
  • 12
    • 0029165971 scopus 로고
    • BDNF enhances the differentiation but not the survival of CNS stem cell- derived neuronal precursors
    • 7643217 1:CAS:528:DyaK2MXnsVOrt7s%3D
    • Ahmed S, Reynolds BA, Weiss S (1995) BDNF enhances the differentiation but not the survival of CNS stem cell- derived neuronal precursors. J Neurosci 15:5765-5778
    • (1995) J Neurosci , vol.15 , pp. 5765-5778
    • Ahmed, S.1    Reynolds, B.A.2    Weiss, S.3
  • 13
    • 0036922542 scopus 로고    scopus 로고
    • Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury
    • Mahmood A, Lu D, Wang L et al (2002) Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury. J Neurotrauma 19:1609-1617 (Pubitemid 36026216)
    • (2002) Journal of Neurotrauma , vol.19 , Issue.12 , pp. 1609-1617
    • Mahmood, A.1    Lu, D.2    Wang, L.3    Chopp, M.4
  • 14
    • 61849173592 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) has proliferative effects on neural stem cells through the truncated TRK-B receptor, MAP kinase, AKT, and STAT-3 signaling pathways
    • 19355925 1:CAS:528:DC%2BC3cXislyjtr0%3D 10.2174/156720209787466028
    • Islam O, Loo TX, Heese K (2009) Brain-derived neurotrophic factor (BDNF) has proliferative effects on neural stem cells through the truncated TRK-B receptor, MAP kinase, AKT, and STAT-3 signaling pathways. Curr Neurovasc Res 6:42-53
    • (2009) Curr Neurovasc Res , vol.6 , pp. 42-53
    • Islam, O.1    Loo, T.X.2    Heese, K.3
  • 15
    • 33644850095 scopus 로고    scopus 로고
    • Adenoviral gene transfer of BDNF and GDNF synergistically prevent motoneuron loss in the nucleus ambiguus
    • DOI 10.1016/j.brainres.2005.12.119, PII S0006899306000084
    • Moro K, Shiotani A, Watabe K et al (2006) Adenoviral gene transfer of BDNF and GDNF synergistically prevent motoneuron loss in the nucleus ambiguus. Brain Res 1076:1-8 (Pubitemid 43376018)
    • (2006) Brain Research , vol.1076 , Issue.1 , pp. 1-8
    • Moro, K.1    Shiotani, A.2    Watabe, K.3    Takeda, Y.4    Saito, K.5    Mori, Y.6    Ogawa, K.7
  • 16
    • 34248326047 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury
    • DOI 10.1097/BRS.0b013e318053ec35, PII 0000763220070515000004
    • Kwon BK, Liu J, Lam C et al (2007) Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. Spine 32:1164-1173 (Pubitemid 46743016)
    • (2007) Spine , vol.32 , Issue.11 , pp. 1164-1173
    • Kwon, B.K.1    Liu, J.2    Lam, C.3    Plunet, W.4    Oschipok, L.W.5    Hauswirth, W.6    Di Polo, A.7    Blesch, A.8    Tetzlaff, W.9
  • 17
    • 77349103200 scopus 로고    scopus 로고
    • Slow-freezing cryopreservation of neural stem cell spheres with different diameters
    • 19895801 1:CAS:528:DC%2BC3cXivFemt7k%3D 10.1016/j.cryobiol.2009.10.013
    • Ma XH, Shi Y, Hou Y et al (2010) Slow-freezing cryopreservation of neural stem cell spheres with different diameters. Cryobiology 60:184-191
    • (2010) Cryobiology , vol.60 , pp. 184-191
    • Ma, X.H.1    Shi, Y.2    Hou, Y.3
  • 18
    • 0029916808 scopus 로고    scopus 로고
    • Liposome-mediated BDNF cDNA transfer in intact and injured rat brain
    • Iwamoto Y, Yang K, Clifton GL et al (1996) Liposome-mediated BDNF cDNA transfer in intact and injured rat brain. Neuroreport 7:609-612 (Pubitemid 26105050)
    • (1996) NeuroReport , vol.7 , Issue.2 , pp. 609-612
    • Iwamoto, Y.1    Yang, K.2    Clifton, G.L.3    Hayes, R.L.4
  • 19
    • 8744261601 scopus 로고    scopus 로고
    • Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells
    • DOI 10.1227/01.NEU.0000145866.25433.FF
    • Boockvar JA, Schouten J, Royo N et al (2005) Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells. Neurosurgery 56:163-171 (Pubitemid 40054003)
    • (2005) Neurosurgery , vol.56 , Issue.1 , pp. 163-171
    • Boockvar, J.A.1    Schouten, J.2    Royo, N.3    Millard, M.4    Spangler, Z.5    Castelbuono, D.6    Snyder, E.7    O'Rourke, D.8    McIntosh, T.9
  • 20
    • 49049085216 scopus 로고    scopus 로고
    • Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida
    • 18707035 10.1016/j.surg.2008.05.009
    • Fauza DO, Jennings RW, Teng YD et al (2008) Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida. Surgery 144:367-373
    • (2008) Surgery , vol.144 , pp. 367-373
    • Fauza, D.O.1    Jennings, R.W.2    Teng, Y.D.3
  • 22
    • 70349247695 scopus 로고    scopus 로고
    • Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery
    • 19660497 10.1016/j.jneumeth.2009.07.029
    • Lubjuhn J, Gastens A, von Wilpert G et al (2009) Functional testing in a mouse stroke model induced by occlusion of the distal middle cerebral artery. J Neurosci Methods 184:95-103
    • (2009) J Neurosci Methods , vol.184 , pp. 95-103
    • Lubjuhn, J.1    Gastens, A.2    Von Wilpert, G.3
  • 23
    • 0042889306 scopus 로고    scopus 로고
    • Two effective behavioral tasks for evaluating sensorimotor dysfunction following traumatic brain injury in mice
    • DOI 10.1016/S0165-0270(03)00212-7
    • Baskin YK, Dietrich WD, Green EJ (2003) Two effective behavioral tasks for evaluating sensorimotor dysfunction following traumatic brain injury in mice. J Neurosci Methods 129:87-93 (Pubitemid 37013669)
    • (2003) Journal of Neuroscience Methods , vol.129 , Issue.1 , pp. 87-93
    • Baskin, Y.K.1    Dietrich, W.D.2    Green, E.J.3
  • 24
    • 33646373685 scopus 로고    scopus 로고
    • Traumatic brain injury in mice deficient in bid: Effects on histopathology and functional outcome
    • 16395279 1:CAS:528:DC%2BD28Xlt1Kjtrc%3D 10.1038/sj.jcbfm.9600258
    • Bermpohl D, You Z, Korsmeyer SJ et al (2006) Traumatic brain injury in mice deficient in bid: effects on histopathology and functional outcome. J Cereb Blood Flow Metab 26:625-633
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 625-633
    • Bermpohl, D.1    You, Z.2    Korsmeyer, S.J.3
  • 25
    • 49349098166 scopus 로고    scopus 로고
    • Transplanted neural stem/progenitor cells generate myelinating oligodendrocytes and schwann cells in spinal cord demyelination and dysmyelination
    • 18586031 1:CAS:528:DC%2BD1cXhtVSgurbM 10.1016/j.expneurol.2008.05.024
    • Mothe AJ, Tator CH (2008) Transplanted neural stem/progenitor cells generate myelinating oligodendrocytes and schwann cells in spinal cord demyelination and dysmyelination. Exp Neurol 213:176-190
    • (2008) Exp Neurol , vol.213 , pp. 176-190
    • Mothe, A.J.1    Tator, C.H.2
  • 26
    • 0029619277 scopus 로고
    • Expression of mRNAs of multiple growth factors and receptors by neuronal cell lines: Detection with RT-PCR
    • DOI 10.1007/BF00970594
    • Zaheer A, Zhong W, Lim R (1995) Expression of mRNAs of multiple growth factors and receptors by neuronal cell lines: detection with RT-PCR. Neurochem Res 20:1457-1463 (Pubitemid 26029137)
    • (1995) Neurochemical Research , vol.20 , Issue.12 , pp. 1457-1463
    • Zaheer, A.1    Zhong, W.2    Lim, R.3
  • 27
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43: An intrinsic determinant of neuronal development and plasticity
    • DOI 10.1016/S0166-2236(96)10072-2, PII S0166223696100722
    • Benowitz LI, Routtenberg A (1997) GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci 20:84-91 (Pubitemid 27050703)
    • (1997) Trends in Neurosciences , vol.20 , Issue.2 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 28
    • 5044222203 scopus 로고    scopus 로고
    • Neural progenitor cell transplants promote long-term functional recovery after traumatic brain injury
    • DOI 10.1016/j.brainres.2004.07.087, PII S0006899304012442
    • Shear DA, Tate MC, Archer DR et al (2004) Neural progenitor cell transplants promote long-term functional recovery after traumatic brain injury. Brain Res 1026:11-22 (Pubitemid 39336412)
    • (2004) Brain Research , vol.1026 , Issue.1 , pp. 11-22
    • Shear, D.A.1    Tate, M.C.2    Archer, D.R.3    Hoffman, S.W.4    Hulce, V.D.5    Laplaca, M.C.6    Stein, D.G.7
  • 29
    • 12944335008 scopus 로고    scopus 로고
    • Neural stem cells express melatonin receptors and neurotrophic factors: Colocalization of the MT1 receptor with neuronal and glial markers
    • 10.1186/1471-2202-5-41
    • Lennard PN, Kristen JA, Lyda MR et al (2004) Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers. BMC Neurosci 5:41
    • (2004) BMC Neurosci , vol.5 , pp. 41
    • Lennard, P.N.1    Kristen, J.A.2    Lyda, M.R.3
  • 30
    • 0038054469 scopus 로고    scopus 로고
    • Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
    • DOI 10.1016/S0014-4886(03)00037-2
    • Lu P, Jones LL, Snyder EY et al (2003) Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 181:115-129 (Pubitemid 36629234)
    • (2003) Experimental Neurology , vol.181 , Issue.2 , pp. 115-129
    • Lu, P.1    Jones, L.L.2    Snyder, E.Y.3    Tuszynski, M.H.4
  • 31
    • 0038452619 scopus 로고    scopus 로고
    • Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways
    • Barnabé-Heider F, Miller FD (2003) Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. J Neurosci 23:5149-5160 (Pubitemid 36793243)
    • (2003) Journal of Neuroscience , vol.23 , Issue.12 , pp. 5149-5160
    • Barnabe-Heider, F.1    Miller, F.D.2
  • 32
    • 0033674870 scopus 로고    scopus 로고
    • Nerve growth factor and neuroimmune interactions in inflammatory diseases
    • 11268353 1:CAS:528:DC%2BD3cXovFyms7g%3D 10.1111/j.1749-6632.2000.tb05392. x
    • Stanisz AM, Stanisz JA (2000) Nerve growth factor and neuroimmune interactions in inflammatory diseases. Ann NY Acad Sci 917:268-272
    • (2000) Ann NY Acad Sci , vol.917 , pp. 268-272
    • Stanisz, A.M.1    Stanisz, J.A.2
  • 33
    • 46649098179 scopus 로고    scopus 로고
    • Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury
    • 18501200 1:CAS:528:DC%2BD1cXosFWntLw%3D 10.1016/j.freeradbiomed.2008.04. 038
    • Ansari MA, Roberts KN, Scheff SW (2008) Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radic Biol Med 45:443-452
    • (2008) Free Radic Biol Med , vol.45 , pp. 443-452
    • Ansari, M.A.1    Roberts, K.N.2    Scheff, S.W.3
  • 34
    • 1842714295 scopus 로고    scopus 로고
    • Synaptophysin: Leading actor or walk-on role in synaptic vesicle exocytosis?
    • DOI 10.1002/bies.20012
    • Valtorta F, Pennuto M, Bonanomi D et al (2004) Synaptophysin: leading actor or walk-on role in synaptic vesicle exocytosis? Bioessays 26:445-453 (Pubitemid 38461625)
    • (2004) BioEssays , vol.26 , Issue.4 , pp. 445-453
    • Valtorta, F.1    Pennuto, M.2    Bonanomi, D.3    Benfenati, F.4
  • 36
    • 33645875591 scopus 로고    scopus 로고
    • Changes in localization of synaptophysin following fluid percussion injury in the rat brain
    • 16497279 1:CAS:528:DC%2BD28XjtFais7o%3D 10.1016/j.brainres.2006.01.063
    • Shojo H, Kibayashi K (2006) Changes in localization of synaptophysin following fluid percussion injury in the rat brain. Brain Res 1078:198-211
    • (2006) Brain Res , vol.1078 , pp. 198-211
    • Shojo, H.1    Kibayashi, K.2
  • 37
    • 0036316727 scopus 로고    scopus 로고
    • ProSAP/Shank proteins - A family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease
    • DOI 10.1046/j.1471-4159.2002.00931.x
    • Boeckers TM, Bockmann J, Kreutz MR et al (2002) ProSAP/Shank proteins: a family of higher order organizing molecules of the post-synaptic density with an emerging role in human neurological disease. J Neurochem 81:903-910 (Pubitemid 34809273)
    • (2002) Journal of Neurochemistry , vol.81 , Issue.5 , pp. 903-910
    • Boeckers, T.M.1    Bockmann, J.2    Kreutz, M.R.3    Gundelfinger, E.D.4
  • 38
    • 0035955643 scopus 로고    scopus 로고
    • Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain shank protein family interact with the cytoskeletal protein alpha-fodrin
    • 11509555 10.1074/jbc.M102454200
    • Böckers TM, Mameza MG, Kreutz MR et al (2001) Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain shank protein family interact with the cytoskeletal protein alpha-fodrin. J Biol Chem 276:40104-40112
    • (2001) J Biol Chem , vol.276 , pp. 40104-40112
    • Böckers, T.M.1    Mameza, M.G.2    Kreutz, M.R.3
  • 39
    • 34547184679 scopus 로고    scopus 로고
    • Maturation of synaptic contacts in differentiating neural stem cells
    • DOI 10.1634/stemcells.2006-0823
    • Liebau S, Vaida B, Storch A (2007) Maturation of synaptic contacts in differentiating neural stem cells. Stem Cells 25:1720-1729 (Pubitemid 47121850)
    • (2007) Stem Cells , vol.25 , Issue.7 , pp. 1720-1729
    • Liebau, S.1    Vaida, B.2    Storch, A.3    Boeckers, T.M.4
  • 40
    • 24144483438 scopus 로고    scopus 로고
    • BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
    • DOI 10.1016/j.pneurobio.2005.06.003, PII S0301008205000663
    • Bramham CR, Messaoudi E (2005) BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76:99-125 (Pubitemid 41242884)
    • (2005) Progress in Neurobiology , vol.76 , Issue.2 , pp. 99-125
    • Bramham, C.R.1    Messaoudi, E.2
  • 41
    • 50249102744 scopus 로고    scopus 로고
    • BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats
    • 18672032 1:CAS:528:DC%2BD1cXhtVKlsLbI 10.1016/j.neuroscience.2008.06.057
    • Ying Z, Roy RR, Zhong H et al (2008) BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats. Neuroscience 155:1070-1078
    • (2008) Neuroscience , vol.155 , pp. 1070-1078
    • Ying, Z.1    Roy, R.R.2    Zhong, H.3
  • 42
    • 33746048845 scopus 로고    scopus 로고
    • BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-β-catenin interactions
    • DOI 10.1083/jcb.200601087
    • Bamji SX, Rico B, Kimes N et al (2006) BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-β-catenin interactions. J Cell Biol 174:289-299 (Pubitemid 44079863)
    • (2006) Journal of Cell Biology , vol.174 , Issue.2 , pp. 289-299
    • Bamji, S.X.1    Rico, B.2    Kimes, N.3    Reichardt, L.F.4
  • 43
    • 0027200571 scopus 로고
    • Neocortex and hippocampus contain distinct distributions of calcium- calmodulin protein kinase II and GAP43 mRNA
    • Jacobs KM, Neve RL, Donoghue JP (1993) Neocortex and hippocampus contain distinct distributions of calcium-calmodulin protein kinase II and GAP43 mRNA. J Comp Neurol 336:151-160 (Pubitemid 23273962)
    • (1993) Journal of Comparative Neurology , vol.336 , Issue.1 , pp. 151-160
    • Jacobs, K.M.1    Neve, R.L.2    Donoghue, J.P.3
  • 44
    • 0032475464 scopus 로고    scopus 로고
    • Traumatic brain injury in rats results in increased expression of Gap- 43 that correlates with behavioral recovery
    • DOI 10.1016/S0304-3940(98)00712-5, PII S0304394098007125
    • Hulsebosch CE, DeWitt DS, Jenkins LW et al (1998) Traumatic brain injury in rats results in increased expression of Gap-43 that correlates with behavioral recovery. Neurosci Lett 255:83-86 (Pubitemid 28494204)
    • (1998) Neuroscience Letters , vol.255 , Issue.2 , pp. 83-86
    • Hulsebosch, C.E.1    Dewitt, D.S.2    Jenkins, L.W.3    Prough, D.S.4
  • 45
    • 0030888165 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates GAP-43 but not Tα1 expression in injured retinal ganglion cells of adult rats
    • DOI 10.1002/(SICI)1097-4547(19970315)47:6<561::AID-JNR1>3.0.CO;2-B
    • Fournier AE, Beer J, Arregui CO et al (1997) Brain-derived neurotrophic factor modulates GAP-43 but not T alpha1 expression in injured retinal ganglion cells of adult rats. J Neurosci Res 47:561-572 (Pubitemid 27138738)
    • (1997) Journal of Neuroscience Research , vol.47 , Issue.6 , pp. 561-572
    • Fournier, A.E.1    Beer, J.2    Arregui, C.O.3    Essagian, C.4    Aguayo, A.J.5    McKerracher, L.6
  • 46
    • 0035110070 scopus 로고    scopus 로고
    • BDNF increases the number of axotomized rat retinal ganglion cells expressing GAP-43, L1, and TAG-1 mRNA - A supportive role for nitric oxide?
    • DOI 10.1006/nbdi.2000.0329
    • Klöcker N, Jung M, Stuermer CA et al (2001) BDNF Increases the number of axotomized rat retinal ganglion cells expressing GAP-43, L1, and TAG-1 mRNA: a supportive role for nitric oxide? Neurobiol Dis 8:103-113 (Pubitemid 32171822)
    • (2001) Neurobiology of Disease , vol.8 , Issue.1 , pp. 103-113
    • Klocker, N.1    Jung, M.2    Stuermer, C.A.O.3    Bahr, M.4
  • 47
    • 0345227300 scopus 로고    scopus 로고
    • Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration
    • DOI 10.1016/S0014-4886(03)00394-7
    • Tobias CA, Shumsky JS, Shibata M et al (2003) Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Exp Neurol 184:97-113 (Pubitemid 37444023)
    • (2003) Experimental Neurology , vol.184 , Issue.1 , pp. 97-113
    • Tobias, C.A.1    Shumsky, J.S.2    Shibata, M.3    Tuszynski, M.H.4    Fischer, I.5    Tessler, A.6    Murray, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.