Proteasomes in lungs from organ donors and patients with end- stage pulmonary diseases

Physiological Research

Volumn 63, Issue 3, 2014, Pages 311-319

  Baker, T A ^a   Bach Iv, H H ^a   Gamelli, R L ^a   Love, R B ^a,b   Majetschak, Matthias ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

20S proteasome; 26S proteasome; Chronic obstructive pulmonary disease; Idiopathic pulmonary fibrosis; Pulmonary sarcoidosis

Indexed keywords

PROTEASOME;

AGED; DONOR; FEMALE; HUMAN; LUNG; LUNG DISEASE; MALE; METABOLISM; MIDDLE AGED; PILOT STUDY;

AGED; FEMALE; HUMANS; LUNG; LUNG DISEASES; MALE; MIDDLE AGED; PILOT PROJECTS; PROTEASOME ENDOPEPTIDASE COMPLEX; TISSUE DONORS;

EID: 84904553381     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. ALBRIGHT JM, ROMERO J, SAINI V, SIXT SU, BIRD MD, KOVACS EJ, GAMELLI RL, PETERS J, MAJETSCHAK M: Proteasomes in human bronchoalveolar lavage fluid after burn and inhalation injury. J Burn Care Res 30: 948-956, 2009.
2. BAKER TA, GENG Q, ROMERO J, PICKEN MM, GAMELLI RL, MAJETSCHAK M: Prolongation of myocardial viability by proteasome inhibition during hypothermic organ preservation. Biochem Biophys Res Commun 401: 548-553, 2010.
3. BALDOVINO S, PICCININI M, ANSELMINO A, RAMONDETTI C, RINAUDO MT, COSTANZO P, SENA LM, ROCCATELLO D: Structural and functional properties of proteasomes purified from the human kidney. J Nephrol 19: 710-716, 2006.
4. BARTON LF, CRUZ M, RANGWALA R, DEEPE GS Jr, MONACO JJ: Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J Immunol 169: 3046-3052, 2002.
5. BAUMEISTER W, WALZ J, ZUHL F, SEEMULLER E: The proteasome: paradigm of a self-compartmentalizing protease. Cell 92: 367-380, 1998.
6. BODAS M, TRAN I, VIJ N: Therapeutic strategies to correct proteostasis-imbalance in chronic obstructive lung diseases. Curr Mol Med 12: 807-814, 2012.
7. BROOKS P, FUERTES G, MURRAY RZ, BOSE S, KNECHT E, RECHSTEINER MC, HENDIL KB, TANAKA K, DYSON J, RIVETT J: Subcellular localization of proteasomes and their regulatory complexes in mammalian cells. Biochem J 346: 155-161, 2000.
8. BUNN PA Jr: The potential role of proteasome inhibitors in the treatment of lung cancer. Clin Cancer Res 10: 4263s-4265s, 2004.
9. CHEN G, LUO Y, WANG X, ZHAO Z, LIU H, ZHANG H, LI Z: A relatively simple and economical protocol for proteomic analyses of human 20S proteasome: Compatible with both scaled-up and scaled-down purifications. Electrophoresis 30: 2422-2430, 2009.
10. CLAVEROL S, BURLET-SCHILTZ O, GIRBAL-NEUHAUSER E, GAIRIN JE, MONSARRAT B: Mapping and structural dissection of human 20 S proteasome using proteomic approaches. Mol Cell Proteomics 1: 567-578, 2002.
11. DAHLMANN B, BECHER B, SOBEK A, EHLERS C, KOPP F, KUEHN L: In vitro activation of the 20S proteasome. Enzyme Protein 47: 274-284, 1993.
12. ELEUTERI AM, KOHANSKI RA, CARDOZO C, ORLOWSKI M: Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity. J Biol Chem 272: 11824-11831, 1997.
13. EYTAN E, ARMON T, HELLER H, BECK S, HERSHKO A: Ubiquitin C-terminal hydrolase activity associated with the 26 S protease complex. J Biol Chem 268: 4668-4674, 1993.
14. FINESCHI S, REITH W, GUERNE PA, DAYER JM, CHIZZOLINI C: Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and upregulating metalloproteinase-1 production in human dermal fibroblasts. FASEB J 20: 562-564, 2006.
15. GALLASTEGUI N, GROLL M: The 26S proteasome: assembly and function of a destructive machine. Trends Biochem Sci 35: 634-642, 2010.
16. GENG Q, ROMERO J, SAINI V, BAKER TA, PICKEN MM, GAMELLI RL, MAJETSCHAK M: A subset of 26S proteasomes is activated at critically low ATP concentrations and contributes to myocardial injury during cold ischemia. Biochem Biophys Res Commun 390: 1136-1141, 2009.
17. GOMES AV, ZONG C, EDMONDSON RD, LI X, STEFANI E, ZHANG J, JONES RC, THYPARAMBIL S, WANG GW, QIAO X, BARDAG-GORCE F, PING P: Mapping the murine cardiac 26S proteasome complexes. Circ Res 99: 362-371, 2006.
18. GROLL M, HUBER R: Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. Biochim Biophys Acta 1695: 33-44, 2004.
19. GUILLAUME B, CHAPIRO J, STROOBANT V, COLAU D, VAN HOLLE B, PARVIZI G, BOUSQUET-DUBOUCH MP, THEATE I, PARMENTIER N, VAN DEN EYNDE BJ: Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules. Proc Natl Acad Sci USA 107: 18599-18604, 2010.
20. HERSHKO A, CIECHANOVER A: The ubiquitin system. Annu Rev Biochem 67: 425-479, 1998.
21. KREMER M, HENN A, KOLB C, BASLER M, MOEBIUS J, GUILLAUME B, LEIST M, VAN DEN EYNDE BJ, GROETTRUP M: Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice. J Immunol 185: 5549-5560, 2010.
22. KWAK MK, HUANG B, CHANG H, KIM JA, KENSLER TW: Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein. Life Sci 80: 2411-2420, 2007.
23. LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
24. MAJETSCHAK M, SORELL LT: Immunological methods to quantify and characterize proteasome complexes: development and application. J Immunol Methods 334: 91-103, 2008.
25. MAJETSCHAK M, PATEL MB, SORELL LT, LIOTTA C, LI S, PHAM SM: Cardiac proteasome dysfunction during cold ischemic storage and reperfusion in a murine heart transplantation model. Biochem Biophys Res Commun 365: 882-888, 2008a.
26. MAJETSCHAK M, PEREZ M, SORELL LT, LAM J, MALDONADO ME, HOFFMAN RW: Circulating 20S proteasome levels in patients with mixed connective tissue disease and systemic lupus erythematosus. Clin Vaccine Immunol 15: 1489-1493, 2008b.
27. MALHOTRA D, THIMMULAPPA R, VIJ N, NAVAS-ACIEN A, SUSSAN T, MERALI S, ZHANG L, KELSEN SG, MYERS A, WISE R, TUDER R, BISWAL S: Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med 180: 1196-1207, 2009.
28. MANNING EW, PATEL MB, GARCIA-COVARRUBIAS L, RAHNEMAI-AZAR AA, PHAM SM, MAJETSCHAK M: Proteasome peptidase activities parallel histomorphological and functional consequences of ischemiareperfusion injury in the lung. Exp Lung Res 35: 284-295, 2009.
29. MATUTE-BELLO G, FREVERT CW, MARTIN TR: Animal models of acute lung injury. Am J Physiol 295: L379-L399, 2008.
30. MENG L, MOHAN R, KWOK BH, ELOFSSON M, SIN N, CREWS CM: Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci USA 96: 10403-10408, 1999.
31. MUTLU GM, BUDINGER GR, WU M, LAM AP, ZIRK A, RIVERA S, URICH D, CHIARELLA SE, GO LH, GHOSH AK, SELMAN M, PARDO A, VARGA J, KAMP DW, CHANDEL NS, SZNAJDER JI, JAIN M: Proteasomal inhibition after injury prevents fibrosis by modulating TGF-beta(1) signalling. Thorax 67: 139-146, 2012.
32. NELSON JE, LOUKISSA A, ALTSCHULLER-FELBERG C, MONACO JJ, FALLON JT, CARDOZO C: Up-regulation of the proteasome subunit LMP7 in tissues of endotoxemic rats. J Lab Clin Med 135: 324-331, 2000.
33. NOVORADOVSKAYA N, LEE J, YU ZX, FERRANS VJ, BRANTLY M: Inhibition of intracellular degradation increases secretion of a mutant form of alpha1-antitrypsin associated with profound deficiency. J Clin Invest 101: 2693-2701, 1998.
34. ORLOWSKI M: The multicatalytic proteinase complex, a major extralysosomal proteolytic system. Biochemistry 29: 10289-10297, 1990.
35. ORLOWSKI M, WILK S: Ubiquitin-independent proteolytic functions of the proteasome. Arch Biochem Biophys 415: 1-5, 2003.
36. ROCK KL, GOLDBERG AL: Degradation of cell proteins and the generation of MHC class I-presented peptides. Annu Rev Immunol 17: 739-779, 1999.
37. RODRIGUEZ KA, EDREY YH, OSMULSKI P, GACZYNSKA M, BUFFENSTEIN R: Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat. PLoS One 7: e35890, 2012.
38. SIJTS EJ, KLOETZEL PM: The role of the proteasome in the generation of MHC class I ligands and immune responses. Cell Mol Life Sci 68: 1491-1502, 2011.
39. TANAKA K, YOSHIMURA T, ICHIHARA A: Role of substrate in reversible activation of proteasomes (multiprotease complexes) by sodium dodecyl sulfate. J Biochem 106: 495-500, 1989.
40. VAN RIJT SH, KELLER IE, JOHN G, KOHSE K, YILDIRIM AÖ, EICKELBERG O, MEINERS S: Acute cigarette smoke exposure impairs proteasome function in the lung. Am J Physiol 303: L814-L823, 2012.
41. VISEKRUNA A, JOERIS T, SCHMIDT N, LAWRENZ M, RITZ JP, BUHR HJ, STEINHOFF U: Comparative expression analysis and characterization of 20S proteasomes in human intestinal tissues: the proteasome pattern as diagnostic tool for IBD patients. Inflamm Bowel Dis 15: 526-533, 2009.
42. WEISS CH, BUDINGER GR, MUTLU GM, JAIN M: Proteasomal regulation of pulmonary fibrosis. Proc Am Thorac Soc 7: 77-83, 2010.
43. ZHAO J, WEI J, MIALKI RK, MALLAMPALLI DF, CHEN BB, COON T, ZOU C, MALLAMPALLI RK, ZHAO Y: F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. Nat Immunol 13: 651-658, 2012.
44. ZHENG J, DASGUPTA A, BIZZOZERO OA: Changes in 20S subunit composition are largely responsible for altered proteasomal activities in experimental autoimmune encephalomyelitis. J Neurochem 121: 486-494, 2012.
45. ZU L, BEDJA D, FOX-TALBOT K, GABRIELSON KL, VAN KAER L, BECKER LC, CAI ZP: Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice. J Mol Cell Cardiol 49: 5-15, 2010.