Proteasome peptidase activities parallel histomorphological and functional consequences of ischemia-reperfusion injury in the lung

Experimental Lung Research

Volumn 35, Issue 4, 2009, Pages 284-295

  Manning, Eddie W ^a   Patel, Mayur B ^a   Garcia Covarrubias, Lisardo ^a   Rahnemai Azar, Amir A ^a   Pham, Si M ^a   Majetschak, Matthias ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Ischemia reperfusion injury; Lung; Lung injury score; Oxygenation; Proteasome; Wet weight dry weight ratio

Indexed keywords

PEPTIDASE; PROTEASOME; PEPTIDE HYDROLASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOPATHOLOGY; ISCHEMIA; LIPID PEROXIDATION; LUNG EDEMA; LUNG FUNCTION; LUNG INJURY; MALE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TISSUE INJURY; ANIMAL; EDEMA; ENZYMOLOGY; KINETICS; LUNG DISEASE; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY;

ANIMALS; EDEMA; KINETICS; LUNG DISEASES; OXIDATIVE STRESS; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; REPERFUSION INJURY;

EID: 67650721180     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140802668823     Document Type: Article

References (35)

1. Baumeister W, Walz J, Zuhl F, Seemuller E: The proteasome: paradigm of a self-compartmentalizing protease. Cell. 1998;92:367-380.
2. Hershko A, Ciechanover A: The ubiquitin system. Annu Rev Biochem. 1998;67:425-479.
3. Orlowski M: The multicatalytic proteinase complex, a major extralysosomal proteolytic system. Biochemistry. 1990;29:10289-10297.
4. Groll M, Huber R: Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. Biochim Biophys Acta. 2004;1695:33-44.
5. Rivett AJ: Proteasomes: multicatalytic proteinase complexes. Biochem J. 1993;291(Pt 1):1-10.
6. Eytan E, Armon T, Heller H, Beck S, Hershko A: Ubiquitin C-terminal hydrolase activity associated with the 26 S protease complex. J Biol Chem. 1993;268:4668-4674.
7. Orlowski M, Wilk S: Ubiquitin-independent proteolytic functions of the proteasome. Arch Biochem Biophys. 2003;415:1-5.
8. Kukan M: Emerging roles of proteasomes in ischemia-reperfusion injury of organs. J Physiol Pharmacol. 2004;55:3-15.
9. Campbell B, Adams J, Shin YK, Lefer AM: Cardioprotective effects of a novel proteasome inhibitor following ischemia and reperfusion in the isolated perfused rat heart. J Mol Cell Cardiol. 1999;31:467-476.
10. Stansfield WE, Moss NC, Willis MS, Tang R, Selzman CH: Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury. Ann Thorac Surg. 2007;84:120-125.
11. Phillips JB, Williams AJ, Adams J, Elliott PJ, Tortella FC: Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke. 2000;31:1686-1693.
12. Alexandrova A, Petrov L, Georgieva A, Kessiova M, Tzvetanova E, Kirkova M, Kukan M: Effect of MG132 on proteasome activity and prooxidant/antioxidant status of rat liver subjected to is-chemia/reperfusion injury. Hepatol Res. 2008;38:393-401.
13. Takaoka M, Itoh M, Kohyama S, Shibata A, Ohkita M, Matsumura Y: Proteasome inhibition attenuates renal endothelin-1 production and the development of ischemic acute renal failure in rats. J Cardiovasc Pharmacol. 2000;36:S225-227.
14. Wang J, Jiang S, Kwong JM, Sanchez RN, Sadun AA, Lam TT: Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats. Brain Res. 2006;1081:211-218.
15. Park JW, Qi WN, Cai Y, Urbaniak JR, Chen LE: Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kappaB activation. Plast Reconstr Surg. 2007;120:1808-1818.
16. Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI: Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J Biol Chem. 2001;276:30057-30063.
17. Powell SR, Wang P, Katzeff H, Shringarpure R, Teoh C, Khaliulin I, Das DK, Davies KJ, Schwalb H: Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome. Antioxid Redox Signal. 2005;7:538-546.
18. Majetschak M, Patel MB, Sorell LT, Liotta C, Li S, Pham SM: Cardiac proteasome dysfunction during cold ischemic storage and reperfusion in a murine heart transplantation model. Biochem Biophys Res Commun. 2008;365:882-888.
19. Keller JN, Huang FF, Zhu H, Yu J, Ho YS, Kindy TS: Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury. J Cereb Blood Flow Metab. 2000;20:1467-1473.
20. Ovechkin AV, Lominadze D, Sedoris KC, Robinson TW, Tyagi SC, Roberts AM: Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions. Arch Physiol Biochem. 2007;113:1-12.
21. Eppinger MJ, Deeb GM, Bolling SF, Ward PA: Mediators of ischemia-reperfusion injury of rat lung. Am J Pathol. 1997;150:1773-1784.
22. Garcia-Covarrubias L, Manning EW 3rd, Sorell LT, Pham SM, Majetschak M: Ubiquitin enhances the Th2 cytokine response and attenuates ischemia-reperfusion injury in the lung. Crit Care Med. 2008;36:979-982.
23. Furue S, Kuwabara K, Mikawa K, Nishina K, Shiga M, Maekawa N, Ueno M, Chikazawa Y, Ono T, Hori Y, Matsukawa A, Yoshinaga M, Obara H: Crucial role of group IIA phospholipase A(2) in oleic acid-induced acute lung injury in rabbits. Am J Respir Crit Care Med. 1999;160:1292-1302.
24. Kandilci HB, Gumusel B, Topaloglu E, Ucar G, Korkusuz P, Ugur Y, Asan E, Demiryurek AT: Effects of ischemic preconditioning on rat lung: role of nitric oxide. Exp Lung Res. 2006;32:287-303.
25. Okada Y, Marchevsky AM, Zuo XJ, Pass JA, Kass RM, Matloff JM, Jordan SC: Accumulation of platelets in rat syngeneic lung transplants: a potential factor responsible for preservation-reperfusion injury. Transplantation. 1997;64:801-806.
26. Patel MB, Majetschak M: Distribution and interrelationship of ubiquitin proteasome pathway component activities and ubiquitin pools in various porcine tissues. Physiol Res. 2007;56:341-350.
27. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
28. Meng L, Mohan R, Kwok BH, Elofsson M, Sin N, Crews CM: Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci U S A. 1999;96:10403-10408.
29. Gunther A, Balser M, Schmidt R, Markart P, Olk A, Borgermann J, Splittgerber FH, Seeger W, Friedrich I: Surfactant abnormalities after single lung transplantation in dogs: impact of broncho-scopic surfactant administration. J Thorac Cardiovasc Surg. 2004;127:344-354.
30. Markart P, Schmidt R, Ruppert C, Hores C, Silber RE, Borgermann J, Gunther A, Friedrich I: Ischemic and endotoxin pre-conditioning reduce lung reperfusion injury-induced surfactant alterations. J Heart Lung Transplant. 2005;24:1680-1689.
31. Das A, Boggaram V: Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression. Am J Physiol Lung Cell Mol Physiol. 2007;292:L74-L84.
32. Sixt SU, Beiderlinden M, Jennissen HP, Peters J: Extracellular proteasome in the human alveolar space: a new housekeeping enzyme? Am J Physiol Lung Cell Mol Physiol. 2007;292:L1280-L1288.
33. Majetschak M, Sorell LT, Patricelli T, Seitz DH, Knoferl MW: Detection and possible role of proteasomes in the bronchoalveolar space of the injured lung. Physiol Res. 2008 Jul 18. [Epub ahead of print].
34. Patel MB, Earle SA, Majetschak M: Dynamics of tissue ubiquitin pools and ubiquitin-proteasome pathway component activities during the systemic response to traumatic shock. Physiol Res. 2007;56:547-557.
35. Farout L, Mary J, Vinh J, Szweda LI, Friguet B: Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Arch Biochem Biophys. 2006;453:135-142.