SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro

Experimental Dermatology

Volumn 23, Issue 7, 2014, Pages 497-503

  O'Kane, Donal ^a   Jackson, Megan V ^a   Kissenpfennig, Adrien ^a   Spence, Shaun ^a   Damkat Thomas, Lindsay ^b   Tolland, Julia P ^b   Smyth, Anita E ^b   Denton, Christopher P ^c   Stuart Elborn, J ^a   Mcauley, Daniel F ^a   O'Kane, Cecilia M ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ULSTER HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Epithelial to mesenchymal transition; Keratinocyte; Transforming growth factor ; Tumor necrosis factor

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; FIBRONECTIN; MATRIX METALLOPROTEINASE; PROTEIN ZO1; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SMAD PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE; UVOMORULIN; VIMENTIN; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; BENZAMIDE DERIVATIVE; COLLAGEN; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL TYPE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDERMIS CELL; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; IN VITRO STUDY; KERATINOCYTE; MORPHOLOGY; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCLERODERMA; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; DOWN REGULATION; EPIDERMIS; FIBROSIS; METABOLISM; SIGNAL TRANSDUCTION;

BENZAMIDES; COLLAGEN; CYTOKINES; DIOXOLES; DOWN-REGULATION; EPIDERMIS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBRONECTINS; FIBROSIS; HUMANS; KERATINOCYTES; MATRIX METALLOPROTEINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; VIMENTIN;

EID: 84904383951     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/exd.12452     Document Type: Article

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