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Volumn 33, Issue 2, 2006, Pages 275-284

Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: Association of interleukin 12 elevation with spontaneous regression of skin sclerosis

Author keywords

Interleukin 12; Systemic sclerosis; Th1; Th2

Indexed keywords

CORTICOSTEROID; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PENICILLAMINE; PREDNISOLONE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 32144454167     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (141)

References (51)
  • 1
    • 0021154318 scopus 로고
    • Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations
    • Roumm AD, Whiteside TL, Medsger TA Jr, Rodnan GP. Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations. Arthritis Rheum 1984;27:645-53.
    • (1984) Arthritis Rheum , vol.27 , pp. 645-653
    • Roumm, A.D.1    Whiteside, T.L.2    Medsger Jr., T.A.3    Rodnan, G.P.4
  • 2
    • 0027464671 scopus 로고
    • Early phenotypic activation of circulating helper memory T cells in scleroderma: Correlation with disease activity
    • Fiocco U, Rosada M, Cozzi L, et al. Early phenotypic activation of circulating helper memory T cells in scleroderma: correlation with disease activity. Ann Rheum Dis 1993;52:272-7.
    • (1993) Ann Rheum Dis , vol.52 , pp. 272-277
    • Fiocco, U.1    Rosada, M.2    Cozzi, L.3
  • 3
    • 0033366780 scopus 로고    scopus 로고
    • T lymphocyte and fibroblast interactions: The case of skin involvement in systemic sclerosis and other examples
    • Chizzolini C. T lymphocyte and fibroblast interactions: the case of skin involvement in systemic sclerosis and other examples. Springer Semin Immunopathol 1999;21:431-50.
    • (1999) Springer Semin Immunopathol , vol.21 , pp. 431-450
    • Chizzolini, C.1
  • 4
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 5
    • 0026601232 scopus 로고
    • Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor-α, and interferon-γ levels in sera from patients with scleroderma
    • Needleman BW, Wigley FM, Stair RW. Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor-α, and interferon-γ levels in sera from patients with scleroderma. Arthritis Rheum 1992;35:67-72.
    • (1992) Arthritis Rheum , vol.35 , pp. 67-72
    • Needleman, B.W.1    Wigley, F.M.2    Stair, R.W.3
  • 6
    • 0025006866 scopus 로고
    • Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis
    • Famularo G, Procopio A, Giacomelli R, et al. Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis. Clin Exp Immunol 1990;81:368-72.
    • (1990) Clin Exp Immunol , vol.81 , pp. 368-372
    • Famularo, G.1    Procopio, A.2    Giacomelli, R.3
  • 7
    • 0031056613 scopus 로고    scopus 로고
    • Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis
    • Hasegawa M, Fujimoto M, Kikuchi K, Takehara K. Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis. J Rheumatol 1997;24:328-32.
    • (1997) J Rheumatol , vol.24 , pp. 328-332
    • Hasegawa, M.1    Fujimoto, M.2    Kikuchi, K.3    Takehara, K.4
  • 8
    • 0031911610 scopus 로고    scopus 로고
    • Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis
    • Hasegawa M, Sato S, Fujimoto M, Ihn H, Kikuchi K, Takehara K. Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis. J Rheumatol 1998;25:308-13.
    • (1998) J Rheumatol , vol.25 , pp. 308-313
    • Hasegawa, M.1    Sato, S.2    Fujimoto, M.3    Ihn, H.4    Kikuchi, K.5    Takehara, K.6
  • 9
    • 0032746822 scopus 로고    scopus 로고
    • Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis
    • Hasegawa M, Sato S, Ihn H, Takehara K. Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis. Rheumatology Oxford 1999;38:612-7.
    • (1999) Rheumatology Oxford , vol.38 , pp. 612-617
    • Hasegawa, M.1    Sato, S.2    Ihn, H.3    Takehara, K.4
  • 10
    • 15644364960 scopus 로고    scopus 로고
    • Type 2 helper T-cell predominance and high CD30 expression in systemic sclerosis
    • Mavalia C, Scaletti C, Romagnani P, et al. Type 2 helper T-cell predominance and high CD30 expression in systemic sclerosis. Am J Pathol 1997;151:1751-8.
    • (1997) Am J Pathol , vol.151 , pp. 1751-1758
    • Mavalia, C.1    Scaletti, C.2    Romagnani, P.3
  • 11
    • 0030981805 scopus 로고    scopus 로고
    • Circulating levels of soluble CD30 are increased in patients with systemic sclerosis (SSc) and correlate with serological and clinical features of the disease
    • Giacomelli R, Cipriani P, Lattanzio R, et al. Circulating levels of soluble CD30 are increased in patients with systemic sclerosis (SSc) and correlate with serological and clinical features of the disease. Clin Exp Immunol 1997;108:42-6.
    • (1997) Clin Exp Immunol , vol.108 , pp. 42-46
    • Giacomelli, R.1    Cipriani, P.2    Lattanzio, R.3
  • 12
    • 0033673989 scopus 로고    scopus 로고
    • Levels of interleukin 12, a cytokine of type 1 helper T cells, are elevated in sera from patients with systemic sclerosis
    • Sato S, Hanakawa H, Hasegawa M, et al. Levels of interleukin 12, a cytokine of type 1 helper T cells, are elevated in sera from patients with systemic sclerosis. J Rheumatol 2000;27:2838-42.
    • (2000) J Rheumatol , vol.27 , pp. 2838-2842
    • Sato, S.1    Hanakawa, H.2    Hasegawa, M.3
  • 13
    • 0034887359 scopus 로고    scopus 로고
    • Circulating γ/Δ T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization
    • Giacomelli R, Cipriani P, Fulminis A, et al. Circulating γ/Δ T lymphocytes from systemic sclerosis (SSc) patients display a T helper (Th) 1 polarization. Clin Exp Immunol 2001;125:310-5.
    • (2001) Clin Exp Immunol , vol.125 , pp. 310-315
    • Giacomelli, R.1    Cipriani, P.2    Fulminis, A.3
  • 14
    • 0036446301 scopus 로고    scopus 로고
    • Abnormal expression of intracellular cytokines and chemokine receptors in peripheral blood T lymphocytes from patients with systemic sclerosis
    • Fujii H, Hasegawa M, Takehara K, Mukaida N. Sato S. Abnormal expression of intracellular cytokines and chemokine receptors in peripheral blood T lymphocytes from patients with systemic sclerosis. Clin Exp Immunol 2002:130:548-56.
    • (2002) Clin Exp Immunol , vol.130 , pp. 548-556
    • Fujii, H.1    Hasegawa, M.2    Takehara, K.3    Mukaida, N.4    Sato, S.5
  • 15
    • 0032824790 scopus 로고    scopus 로고
    • Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis: A quantitative study of open lung biopsies
    • Majumdar S, Li D, Ansari T, et al. Different cytokine profiles in cryptogenic fibrosing alveolitis and fibrosing alveolitis associated with systemic sclerosis: a quantitative study of open lung biopsies. Eur Respir J 1999;14:251-7.
    • (1999) Eur Respir J , vol.14 , pp. 251-257
    • Majumdar, S.1    Li, D.2    Ansari, T.3
  • 16
    • 0033767899 scopus 로고    scopus 로고
    • Severe organ involvement in systemic sclerosis with diffuse scleroderma
    • Steen VD, Medsger TA Jr. Severe organ involvement in systemic sclerosis with diffuse scleroderma. Arthritis Rheum 2000;43:2437-44.
    • (2000) Arthritis Rheum , vol.43 , pp. 2437-2444
    • Steen, V.D.1    Medsger Jr., T.A.2
  • 18
    • 0033758222 scopus 로고    scopus 로고
    • Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: High-dose versus low-dose penicillamine trial
    • Clements PJ, Hurwitz EL, Wong WK, et al. Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: high-dose versus low-dose penicillamine trial. Arthritis Rheum 2000;43:2445-54.
    • (2000) Arthritis Rheum , vol.43 , pp. 2445-2454
    • Clements, P.J.1    Hurwitz, E.L.2    Wong, W.K.3
  • 19
    • 0018887574 scopus 로고
    • Preliminary criteria for the classification of systemic sclerosis (scleroderma)
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
    • (1980) Arthritis Rheum , vol.23 , pp. 581-590
  • 20
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): Classification, subsets, and pathogenesis
    • LeRoy EC, Krieg T, Black C, et al. Scleroderma (systemic sclerosis): classification, subsets, and pathogenesis. J Rheumatol 1988;15:202-5.
    • (1988) J Rheumatol , vol.15 , pp. 202-205
    • Leroy, E.C.1    Krieg, T.2    Black, C.3
  • 21
    • 0027729083 scopus 로고
    • Skin thickness score in systemic sclerosis: An assessment of interobserver variability in 3 independent studies
    • Clements PJ, Lachenbruch PA, Seibold JR, et al. Skin thickness score in systemic sclerosis: an assessment of interobserver variability in 3 independent studies. J Rheumatol 1993;20:1892-6.
    • (1993) J Rheumatol , vol.20 , pp. 1892-1896
    • Clements, P.J.1    Lachenbruch, P.A.2    Seibold, J.R.3
  • 22
    • 0028043326 scopus 로고
    • Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
    • Trinchieri G. Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 1994;84:4008-27.
    • (1994) Blood , vol.84 , pp. 4008-4027
    • Trinchieri, G.1
  • 23
    • 0035003174 scopus 로고    scopus 로고
    • A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR
    • Meijerink J, Mandigers C, van de Locht L, Tonnissen E, Goodsaid F, Raemaekers J. A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR. J Mol Diag 2001;3:55-61.
    • (2001) J Mol Diag , vol.3 , pp. 55-61
    • Meijerink, J.1    Mandigers, C.2    Van De Locht, L.3    Tonnissen, E.4    Goodsaid, F.5    Raemaekers, J.6
  • 24
    • 0034704593 scopus 로고    scopus 로고
    • Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1
    • Gu L, Tseng S, Horner RM, Tam C, Loda M, Rollins BJ. Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1. Nature 2000;404:407-11.
    • (2000) Nature , vol.404 , pp. 407-411
    • Gu, L.1    Tseng, S.2    Horner, R.M.3    Tam, C.4    Loda, M.5    Rollins, B.J.6
  • 25
    • 0027959893 scopus 로고
    • Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
    • Sad S, Mosmann TR. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J Immunol 1994;153:3514-22.
    • (1994) J Immunol , vol.153 , pp. 3514-3522
    • Sad, S.1    Mosmann, T.R.2
  • 26
    • 0036064618 scopus 로고    scopus 로고
    • Scleroderma and Smads: Dysfunctional Smad family dynamics culminating in fibrosis
    • Varga J. Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis. Arthritis Rheum 2002;46:1703-13.
    • (2002) Arthritis Rheum , vol.46 , pp. 1703-1713
    • Varga, J.1
  • 27
    • 0034730629 scopus 로고    scopus 로고
    • Tumor necrosis factor-α inhibits transforming growth factor-β/Smad signaling in human dermal fibroblasts via AP-1 activation
    • Verrecchia F, Pessah M, Atfi A, Mauviel A. Tumor necrosis factor-α inhibits transforming growth factor-β/Smad signaling in human dermal fibroblasts via AP-1 activation. J Biol Chem 2000;275:30226-31.
    • (2000) J Biol Chem , vol.275 , pp. 30226-30231
    • Verrecchia, F.1    Pessah, M.2    Atfi, A.3    Mauviel, A.4
  • 28
    • 0141564934 scopus 로고    scopus 로고
    • Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor α
    • Chizzolini C, Parel Y, De Luca C, et al. Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor α. Arthritis Rheum 2003;48:2593-604.
    • (2003) Arthritis Rheum , vol.48 , pp. 2593-2604
    • Chizzolini, C.1    Parel, Y.2    De Luca, C.3
  • 29
    • 0022521659 scopus 로고
    • Inhibition of excessive scleroderma fibroblast collagen production by recombinant γ-interferon. Association with a coordinate decrease in types I and III procollagen messenger RNA levels
    • Rosenbloom J, Feldman G, Freundlich B, Jimenez SA. Inhibition of excessive scleroderma fibroblast collagen production by recombinant γ-interferon. Association with a coordinate decrease in types I and III procollagen messenger RNA levels. Arthritis Rheum 1986;29:851-6.
    • (1986) Arthritis Rheum , vol.29 , pp. 851-856
    • Rosenbloom, J.1    Feldman, G.2    Freundlich, B.3    Jimenez, S.A.4
  • 30
    • 0029878115 scopus 로고    scopus 로고
    • A multicenter trial of recombinant human interferon γ in patients with systemic sclerosis: Effects on cutaneous fibrosis and interleukin 2 receptor levels
    • Polisson RP, Gilkeson GS, Pyun EH, Pisetsky DS, Smith EA, Simon LS. A multicenter trial of recombinant human interferon γ in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels. J Rheumatol 1996;23:654-8.
    • (1996) J Rheumatol , vol.23 , pp. 654-658
    • Polisson, R.P.1    Gilkeson, G.S.2    Pyun, E.H.3    Pisetsky, D.S.4    Smith, E.A.5    Simon, L.S.6
  • 31
    • 7844237877 scopus 로고    scopus 로고
    • Interferon-γ in the treatment of systemic sclerosis: A randomized controlled multicentre trial
    • Grassegger A, Schuler G, Hessenberger G, et al. Interferon-γ in the treatment of systemic sclerosis: a randomized controlled multicentre trial. Br J Dermatol 1998;139:639-48.
    • (1998) Br J Dermatol , vol.139 , pp. 639-648
    • Grassegger, A.1    Schuler, G.2    Hessenberger, G.3
  • 32
    • 0030938148 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-β production by interleukin-12
    • Marth T, Strober W, Seder RA, Kelsall BL. Regulation of transforming growth factor-β production by interleukin-12. Eur J Immunol 1997;27:1213-20.
    • (1997) Eur J Immunol , vol.27 , pp. 1213-1220
    • Marth, T.1    Strober, W.2    Seder, R.A.3    Kelsall, B.L.4
  • 33
    • 0034809458 scopus 로고    scopus 로고
    • Effect of IL-12 encoding plasmid administration on tight-skin mouse
    • Tsuji-Yamada J, Nakazawa M, Takahashi K, et al. Effect of IL-12 encoding plasmid administration on tight-skin mouse. Biochem Biophys Res Commun 2001;280:707-12.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 707-712
    • Tsuji-Yamada, J.1    Nakazawa, M.2    Takahashi, K.3
  • 34
    • 0026520977 scopus 로고
    • Interleukin-4 stimulates collagen gene expression in human fibroblast monolayer cultures. Potential role in fibrosis
    • Gillery P, Fertin C, Nicolas JF, et al. Interleukin-4 stimulates collagen gene expression in human fibroblast monolayer cultures. Potential role in fibrosis. FEBS Lett 1992;302:231-4.
    • (1992) FEBS Lett , vol.302 , pp. 231-234
    • Gillery, P.1    Fertin, C.2    Nicolas, J.F.3
  • 35
    • 0025989368 scopus 로고
    • Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6
    • Duncan MR, Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6. J Invest Dermatol 1991;97:686-92.
    • (1991) J Invest Dermatol , vol.97 , pp. 686-692
    • Duncan, M.R.1    Berman, B.2
  • 36
    • 0033121274 scopus 로고    scopus 로고
    • Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A
    • Kawaguchi Y, Hara M, Wright TM. Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A. J Clin Invest 1999;103:1253-60.
    • (1999) J Clin Invest , vol.103 , pp. 1253-1260
    • Kawaguchi, Y.1    Hara, M.2    Wright, T.M.3
  • 37
    • 0026767273 scopus 로고
    • Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma
    • Feghali CA, Host KL, Boulware DW, Levy LS. Mechanisms of pathogenesis in scleroderma. I. Overproduction of interleukin 6 by fibroblasts cultured from affected skin sites of patients with scleroderma. J Rheumatol 1992;19:1207-11.
    • (1992) J Rheumatol , vol.19 , pp. 1207-1211
    • Feghali, C.A.1    Host, K.L.2    Boulware, D.W.3    Levy, L.S.4
  • 38
    • 0036262665 scopus 로고    scopus 로고
    • CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse
    • Saito E, Fujimoto M, Hasegawa M, et al. CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse. J Clin Invest 2002;109:1453-62.
    • (2002) J Clin Invest , vol.109 , pp. 1453-1462
    • Saito, E.1    Fujimoto, M.2    Hasegawa, M.3
  • 39
    • 0034856397 scopus 로고    scopus 로고
    • Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis
    • Sato S, Hasegawa M, Takehara K. Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis. J Dermatol Sci 2001;27:140-6.
    • (2001) J Dermatol Sci , vol.27 , pp. 140-146
    • Sato, S.1    Hasegawa, M.2    Takehara, K.3
  • 40
    • 0027943188 scopus 로고
    • Interleukin-10 modulates type I collagen and matrix metalloprotease gene expression in cultured human skin fibroblasts
    • Reitamo S, Remitz A, Tamai K, Uitto I. Interleukin-10 modulates type I collagen and matrix metalloprotease gene expression in cultured human skin fibroblasts. J Clin Invest 1994;94:2489-92.
    • (1994) J Clin Invest , vol.94 , pp. 2489-2492
    • Reitamo, S.1    Remitz, A.2    Tamai, K.3    Uitto, I.4
  • 41
    • 0031610934 scopus 로고    scopus 로고
    • Role of interleukin-10 in the lung response to silica in mice
    • Huaux F, Louahed J, Hudspith B, et al. Role of interleukin-10 in the lung response to silica in mice. Am J Respir Cell Mol Biol 1998;18:51-9.
    • (1998) Am J Respir Cell Mol Biol , vol.18 , pp. 51-59
    • Huaux, F.1    Louahed, J.2    Hudspith, B.3
  • 42
    • 0033950356 scopus 로고    scopus 로고
    • Repeated concanavalin a challenge in mice induces an interleukin 10-producing phenotype and liver fibrosis
    • Louis H, Le Moine A, Quertinmont E, et al. Repeated concanavalin A challenge in mice induces an interleukin 10-producing phenotype and liver fibrosis. Hepatology 2000;31:381-90.
    • (2000) Hepatology , vol.31 , pp. 381-390
    • Louis, H.1    Le Moine, A.2    Quertinmont, E.3
  • 43
    • 23644440037 scopus 로고    scopus 로고
    • Clinical and laboratory measures of disease activity in systemic sclerosis
    • Veale DJ, Fearon UM, Henshaw K, et al. Clinical and laboratory measures of disease activity in systemic sclerosis [abstract]. Arthritis Rheum 2001;Suppl 44:S327.
    • (2001) Arthritis Rheum , vol.44
    • Veale, D.J.1    Fearon, U.M.2    Henshaw, K.3
  • 44
    • 0033000530 scopus 로고    scopus 로고
    • Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis
    • Atamas SP, Yurovsky VV, Wise R, et al. Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis. Arthritis Rheum 1999;42:1168-78.
    • (1999) Arthritis Rheum , vol.42 , pp. 1168-1178
    • Atamas, S.P.1    Yurovsky, V.V.2    Wise, R.3
  • 45
    • 85080850202 scopus 로고    scopus 로고
    • Th2-type cytokines and the Fas way to pulmonary fibrosis: Comment on the article by Atamas et al
    • Spinozzi F, Agea E, Russano A, et al. Th2-type cytokines and the Fas way to pulmonary fibrosis: comment on the article by Atamas et al [letter]. Arthritis Rheum 2000;43:236-8.
    • (2000) Arthritis Rheum , vol.43 , pp. 236-238
    • Spinozzi, F.1    Agea, E.2    Russano, A.3
  • 46
    • 0032974438 scopus 로고    scopus 로고
    • Augmented production of chemokines (MCP-1, MTP-1a, and MIP-1β) in patients with systemic sclerosis: MCP-1 and MIP-1α may be involved in the development of pulmonary fibrosis
    • Hasegawa M, Sato S, Takehara K. Augmented production of chemokines (MCP-1, MTP-1a, and MIP-1β) in patients with systemic sclerosis: MCP-1 and MIP-1α may be involved in the development of pulmonary fibrosis. Clin Exp Immunol 1999;117:159-65.
    • (1999) Clin Exp Immunol , vol.117 , pp. 159-165
    • Hasegawa, M.1    Sato, S.2    Takehara, K.3
  • 47
    • 0035149215 scopus 로고    scopus 로고
    • Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: Role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis
    • Distler O, Pap T, Kowal-Bielecka O, et al. Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis. Arthritis Rheum 2001;44:2665-78.
    • (2001) Arthritis Rheum , vol.44 , pp. 2665-2678
    • Distler, O.1    Pap, T.2    Kowal-Bielecka, O.3
  • 48
    • 0041333160 scopus 로고    scopus 로고
    • Role of monocyte chemoattractant protein-1 and its receptor, CCR-2, in the pathogenesis of bleomycin-induced scleroderma
    • Yamamoto T, Nishioka K. Role of monocyte chemoattractant protein-1 and its receptor, CCR-2, in the pathogenesis of bleomycin-induced scleroderma. J Invest Dermatol 2003;121:510-6.
    • (2003) J Invest Dermatol , vol.121 , pp. 510-516
    • Yamamoto, T.1    Nishioka, K.2
  • 49
    • 0028009496 scopus 로고
    • Immunocytochemical localization and serologic detection of transforming growth factor β1: Association with type I procollagen and inflammatory cell markers in diffuse and limited systemic sclerosis, morphea, and Raynaud's phenomenon
    • Higley H, Persichitte K, Chu S, Waegell W, Vancheeswaran R, Black C. Immunocytochemical localization and serologic detection of transforming growth factor β1: association with type I procollagen and inflammatory cell markers in diffuse and limited systemic sclerosis, morphea, and Raynaud's phenomenon. Arthritis Rheum 1994;37:278-88.
    • (1994) Arthritis Rheum , vol.37 , pp. 278-288
    • Higley, H.1    Persichitte, K.2    Chu, S.3    Waegell, W.4    Vancheeswaran, R.5    Black, C.6
  • 50
    • 0029671316 scopus 로고    scopus 로고
    • TGF-β contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice
    • Maeda H, Shiraishi A. TGF-β contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice. J Immunol 1996;156:73-8.
    • (1996) J Immunol , vol.156 , pp. 73-78
    • Maeda, H.1    Shiraishi, A.2
  • 51
    • 0035096772 scopus 로고    scopus 로고
    • Natural killer type 2 bias in remission of multiple sclerosis
    • Takahashi K, Miyake S, Kondo T. et al. Natural killer type 2 bias in remission of multiple sclerosis. J Clin Invest 2001;107:R23-R9.
    • (2001) J Clin Invest , vol.107
    • Takahashi, K.1    Miyake, S.2    Kondo, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.