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Volumn 103, Issue 2, 2014, Pages 268-280

Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction

Author keywords

Cardiac fibroblast; Diastolic dysfunction; Extracellular matrix; Fibrosis; Hypertrophy; Matricellular proteins; Tissue inhibitor of metalloproteinase

Indexed keywords

ANGIOTENSIN II; COAT PROTEIN COMPLEX II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; INTERLEUKIN 6; MATRIX METALLOPROTEINASE 14; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL COLLAGENASE; OSTEONECTIN; OSTEOPONTIN; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROTEIN LYSINE 6 OXIDASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

EID: 84904337178     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvu072     Document Type: Article
Times cited : (101)

References (80)
  • 1
    • 84866342680 scopus 로고    scopus 로고
    • Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease
    • Fan D, Takawale A, Lee J, Kassiri Z. Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease. Fibrogenesis Tissue Repair 2012;5:15
    • (2012) Fibrogenesis Tissue Repair , vol.5 , pp. 15
    • Fan, D.1    Takawale, A.2    Lee, J.3    Kassiri, Z.4
  • 2
    • 84862676645 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases (TIMPs) in heart failure
    • Moore L, Fan D, Basu R, Kandalam V, Kassiri Z. Tissue inhibitor of metalloproteinases (TIMPs) in heart failure. Heart Fail Rev 2012;17:693-706
    • (2012) Heart Fail Rev , vol.17 , pp. 693-706
    • Moore, L.1    Fan, D.2    Basu, R.3    Kandalam, V.4    Kassiri, Z.5
  • 3
    • 77149164774 scopus 로고    scopus 로고
    • Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics
    • Rodriguez D, Morrison CJ, Overall CM. Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics. Biochim Biophys Acta 2010;1803:39-54
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 39-54
    • Rodriguez, D.1    Morrison, C.J.2    Overall, C.M.3
  • 4
    • 80855148864 scopus 로고    scopus 로고
    • Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress
    • Kandalam V, Basu R, Moore L, Fan D,Wang X, Jaworski DM, Oudit GY, Kassiri Z. Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress. Circulation 2011;124:2094-2105
    • (2011) Circulation , vol.124 , pp. 2094-2105
    • Kandalam, V.1    Basu, R.2    Moore, L.3    Fan, D.4    Wang, X.5    Jaworski, D.M.6    Oudit, G.Y.7    Kassiri, Z.8
  • 5
    • 84860145209 scopus 로고    scopus 로고
    • Matricellular proteins in cardiac adaptation and disease
    • Frangogiannis NG. Matricellular proteins in cardiac adaptation and disease. Physiol Rev 2012;92:635-688
    • (2012) Physiol Rev , vol.92 , pp. 635-688
    • Frangogiannis, N.G.1
  • 6
    • 84874626027 scopus 로고    scopus 로고
    • Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: Moving beyond collagen expression
    • Goldsmith EC, Bradshaw AD, Spinale FG. Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: Moving beyond collagen expression. Am J Physiol Cell Physiol 2013;304:C393-C402
    • (2013) Am J Physiol Cell Physiol , vol.304
    • Goldsmith, E.C.1    Bradshaw, A.D.2    Spinale, F.G.3
  • 7
    • 77649273607 scopus 로고    scopus 로고
    • TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'
    • Vanhoutte D, Heymans S. TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'. J Mol Cell Cardiol 2010;48:445-453
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 445-453
    • Vanhoutte, D.1    Heymans, S.2
  • 8
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • Wynn TA, Ramalingam TR. Mechanisms of fibrosis: Therapeutic translation for fibrotic disease. Nat Med 2012;18:1028-1040
    • (2012) Nat Med , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 9
    • 0034032576 scopus 로고    scopus 로고
    • Angiotensin II, adhesion, and cardiac fibrosis
    • DOI 10.1016/S0008-6363(00)00044-4, PII S0008636300000444
    • Schnee JM, HsuehWA. Angiotensin II, adhesion, and cardiac fibrosis. Cardiovasc Res 2000; 46:264-268 (Pubitemid 30204598)
    • (2000) Cardiovascular Research , vol.46 , Issue.2 , pp. 264-268
    • Schnee, J.M.1    Hsueh, W.A.2
  • 10
    • 0034595310 scopus 로고    scopus 로고
    • Defining diastolic heart failure: A call for standardized diagnostic criteria
    • Vasan RS, Levy D. Defining diastolic heart failure: A call for standardized diagnostic criteria. Circulation 2000;101:2118-2121 (Pubitemid 30233178)
    • (2000) Circulation , vol.101 , Issue.17 , pp. 2118-2121
    • Vasan, R.S.1    Levy, D.2
  • 14
    • 70350418732 scopus 로고    scopus 로고
    • Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in TIMP3- deficient heart
    • Kassiri Z, Defamie V, Hariri M, Oudit GY, Anthwal S, Dawood F, Liu P, Khokha R. Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in TIMP3- deficient heart. J Biol Chem 2009;284:29893-29904
    • (2009) J Biol Chem , vol.284 , pp. 29893-29904
    • Kassiri, Z.1    Defamie, V.2    Hariri, M.3    Oudit, G.Y.4    Anthwal, S.5    Dawood, F.6    Liu, P.7    Khokha, R.8
  • 18
    • 84864609802 scopus 로고    scopus 로고
    • Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: A metabolic contribution to heart failure with normal ejection fraction
    • Mori J, Basu R, McLean BA, Das SK, Zhang L, Patel VB,Wagg CS, Kassiri Z, LopaschukGD, Oudit GY. Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: A metabolic contribution to heart failure with normal ejection fraction. Circ Heart Fail 2012;5:493-503
    • (2012) Circ Heart Fail , vol.5 , pp. 493-503
    • Mori, J.1    Basu, R.2    McLean, B.A.3    Das, S.K.4    Zhang, L.5    Patel, V.B.6    Wagg, C.S.7    Kassiri, Z.8    Lopaschuk, G.D.9    Oudit, G.Y.10
  • 20
    • 77949366805 scopus 로고    scopus 로고
    • TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation
    • KandalamV, Basu R, AbrahamT,Wang X, Soloway PD, JaworskiDM,OuditGY, Kassiri Z. TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation. Circ Res 2010;106: 796-808
    • (2010) Circ Res , vol.106 , pp. 796-808
    • Kandalam, V.1    Basu, R.2    Abraham, T.3    Wang, X.4    Soloway, P.D.5    Jaworski, D.M.6    Oudit, G.Y.7    Kassiri, Z.8
  • 21
    • 72249100585 scopus 로고    scopus 로고
    • Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function
    • Basu R, OuditGY,Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. Am J Physiol Heart Circ Physiol 2009;297:H2096-H2108
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Basu, R.1    Oudit, G.Y.2    Wang, X.3    Zhang, L.4    Ussher, J.R.5    Lopaschuk, G.D.6    Kassiri, Z.7
  • 23
  • 27
    • 59849090694 scopus 로고    scopus 로고
    • Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: Role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing
    • Bradshaw AD, Baicu CF, Rentz TJ, Van Laer AO, Boggs J, Lacy JM, Zile MR. Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing. Circulation 2009;119:269-280
    • (2009) Circulation , vol.119 , pp. 269-280
    • Bradshaw, A.D.1    Baicu, C.F.2    Rentz, T.J.3    Van Laer, A.O.4    Boggs, J.5    Lacy, J.M.6    Zile, M.R.7
  • 28
    • 33846225093 scopus 로고    scopus 로고
    • Isolation and culture of adult mouse cardiac myocytes
    • DOI 10.1385/1-59745-214-9:271, Cardiovascular Proteomics: Methods and Protocols
    • O'Connell TD, Rodrigo MC, Simpson PC. Isolation and culture of adult mouse cardiac myocytes. Methods Mol Biol 2007;357:271-296 (Pubitemid 350183253)
    • (2007) Methods in Molecular Biology , vol.357 , pp. 271-296
    • O'Connell, T.D.1    Rodrigo, M.C.2    Simpson, P.C.3
  • 29
    • 78549277139 scopus 로고    scopus 로고
    • Loss of PI3Kgamma enhances CAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress
    • Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, LiangW, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY. Loss of PI3Kgamma enhances CAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circ Res 2010;107:1275-1289
    • (2010) Circ Res , vol.107 , pp. 1275-1289
    • Guo, D.1    Kassiri, Z.2    Basu, R.3    Chow, F.L.4    Kandalam, V.5    Damilano, F.6    Liang, W.7    Izumo, S.8    Hirsch, E.9    Penninger, J.M.10    Backx, P.H.11    Oudit, G.Y.12
  • 31
    • 41449111778 scopus 로고    scopus 로고
    • Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells
    • Totlandsdal AI, Skomedal T, Lag M, Osnes JB, Refsnes M. Pro-inflammatory potential of ultrafine particles in mono- and co-cultures of primary cardiac cells. Toxicology 2008;247: 23-32
    • (2008) Toxicology , vol.247 , pp. 23-32
    • Totlandsdal, A.I.1    Skomedal, T.2    Lag, M.3    Osnes, J.B.4    Refsnes, M.5
  • 32
    • 77749254756 scopus 로고    scopus 로고
    • Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3K{gamma}-dependent manner
    • Awad AE, Kandalam V, Chakrabarti S, Wang X, Penninger JM, Davidge ST, Oudit GY, Kassiri Z. Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3K{gamma}-dependent manner. Am J Physiol Cell Physiol 2010;298:C679-C692
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Awad, A.E.1    Kandalam, V.2    Chakrabarti, S.3    Wang, X.4    Penninger, J.M.5    Davidge, S.T.6    Oudit, G.Y.7    Kassiri, Z.8
  • 33
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • DOI 10.1038/nprot.2007.30, PII NPROT.2006.30
    • Liang CC, Park AY, Guan JL. In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007;2:329-333 (Pubitemid 47040047)
    • (2007) Nature Protocols , vol.2 , Issue.2 , pp. 329-333
    • Liang, C.-C.1    Park, A.Y.2    Guan, J.-L.3
  • 34
    • 0036163604 scopus 로고    scopus 로고
    • Senescence associated β galactosidase activity in human retinal pigment epithelial cells exposed to mildhyperoxia in vitro
    • DOI 10.1136/bjo.86.2.159
    • Honda S, Hjelmeland LM, Handa JT. Senescence associated beta galactosidase activity in human retinal pigment epithelial cells exposed to mild hyperoxia in vitro. Br J Ophthalmol 2002;86:159-162 (Pubitemid 34127539)
    • (2002) British Journal of Ophthalmology , vol.86 , Issue.2 , pp. 159-162
    • Honda, S.1    Hjelmeland, L.M.2    Handa, J.T.3
  • 35
    • 0034714202 scopus 로고    scopus 로고
    • TIMP-2 is required for efficient activation of proMMP-2 in vivo
    • Wang Z, Juttermann R, Soloway PD. TIMP-2 is required for efficient activation of proMMP-2 in vivo. J Biol Chem 2000;275:26411-26415
    • (2000) J Biol Chem , vol.275 , pp. 26411-26415
    • Wang, Z.1    Juttermann, R.2    Soloway, P.D.3
  • 36
    • 84888020850 scopus 로고    scopus 로고
    • Ventricular remodeling in heart failure with preserved ejection fraction
    • Shah AM. Ventricular remodeling in heart failure with preserved ejection fraction. Curr Heart Fail Rep 2013;10:341-349
    • (2013) Curr Heart Fail Rep , vol.10 , pp. 341-349
    • Shah, A.M.1
  • 37
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle
    • Zile MR, Baicu CF, Gaasch WH. Diastolic heart failure-abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 2004;350:1953-1959
    • (2004) N Engl J Med , vol.350 , pp. 1953-1959
    • Zile, M.R.1    Baicu, C.F.2    Gaasch, W.H.3
  • 39
    • 77649274059 scopus 로고    scopus 로고
    • Cardiac extracellular matrix remodeling: Fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC)
    • McCurdy S, Baicu CF, Heymans S, Bradshaw AD. Cardiac extracellular matrix remodeling: fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). J Mol Cell Cardiol 2010;48:544-549
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 544-549
    • McCurdy, S.1    Baicu, C.F.2    Heymans, S.3    Bradshaw, A.D.4
  • 41
    • 1242272154 scopus 로고    scopus 로고
    • ERK1/2 and JNKs, but not p38 Kinase, Are Involved in Reactive Oxygen Species-Mediated Induction of Osteopontin Gene Expression by Angiotensin II and Interleukin-1β in Adult Rat Cardiac Fibroblasts
    • DOI 10.1002/jcp.10419
    • Xie Z, Singh M, Singh K. ERK1/2 and JNKs, but not p38 kinase, are involved in reactive oxygen species-mediated induction of osteopontin gene expression by angiotensin II and interleukin-1beta in adult rat cardiac fibroblasts. J Cell Physiol 2004;198:399-407 (Pubitemid 38235035)
    • (2004) Journal of Cellular Physiology , vol.198 , Issue.3 , pp. 399-407
    • Xie, Z.1    Singh, M.2    Singh, K.3
  • 45
    • 84864005386 scopus 로고    scopus 로고
    • Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload
    • BaicuCF, ZhangY, Van LaerAO, Renaud L, Zile MR, BradshawAD. Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload. Am J Physiol Heart Circ Physiol 2012;303:H234-H240
    • (2012) Am J Physiol Heart Circ Physiol , vol.303
    • Baicu, C.F.1    Zhang, Y.2    Van Laer, A.O.3    Renaud, L.4    Zile, M.R.5    Bradshaw, A.D.6
  • 46
    • 20744443845 scopus 로고    scopus 로고
    • Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
    • DOI 10.1016/j.matbio.2005.04.002, PII S0945053X05000429
    • Zuurmond AM, van der Slot-Verhoeven AJ, van Dura EA,DeGroot J, Bank RA. Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: implications for collagen cross-linking and treatment of fibrosis. Matrix Biol 2005;24: 261-270 (Pubitemid 40853876)
    • (2005) Matrix Biology , vol.24 , Issue.4 , pp. 261-270
    • Zuurmond, A.-M.1    Van Der Slot-Verhoeven, A.J.2    Van Dura, E.A.3    De Groot, J.4    Bank, R.A.5
  • 47
    • 0036377858 scopus 로고    scopus 로고
    • The kyphoscoliotic type of Ehlers-Danlos syndrome (type VI): Differential effects on the hydroxylation of lysine in collagens I and II revealed by analysis of cross-linked telopeptides from urine
    • DOI 10.1016/S1096-7192(02)00036-7, PII S1096719202000367
    • Eyre D, Shao P, Weis MA, Steinmann B. The kyphoscoliotic type of Ehlers-Danlos syndrome (type VI): differential effects on the hydroxylation of lysine in collagens I and II revealed by analysis of cross-linked telopeptides from urine. Mol Genet Metab 2002;76:211-216 (Pubitemid 35034554)
    • (2002) Molecular Genetics and Metabolism , vol.76 , Issue.3 , pp. 211-216
    • Eyre, D.1    Shao, P.2    Ann Weis, M.3    Steinmann, B.4
  • 49
    • 0032741126 scopus 로고    scopus 로고
    • Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: Prevalence and mortality in a population-based cohort
    • Vasan RS, LarsonMG, Benjamin EJ, Evans JC, Reiss CK, Levy D. Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: Prevalence and mortality in a population-based cohort. J Am Coll Cardiol 1999;33:1948-1955
    • (1999) J Am Coll Cardiol , vol.33 , pp. 1948-1955
    • Vasan, R.S.1    Larson, M.G.2    Benjamin, E.J.3    Evans, J.C.4    Reiss, C.K.5    Levy, D.6
  • 53
    • 84866731794 scopus 로고    scopus 로고
    • The many faces of heart failure with preserved ejection fraction
    • Shah AM, Pfeffer MA. The many faces of heart failure with preserved ejection fraction. Nat Rev Cardiol 2012;9:555-556
    • (2012) Nat Rev Cardiol , vol.9 , pp. 555-556
    • Shah, A.M.1    Pfeffer, M.A.2
  • 57
    • 84879748718 scopus 로고    scopus 로고
    • A novel paradigm for heart failure with preserved ejection fraction: Comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
    • Paulus WJ, Tschope C. A novel paradigm for heart failure with preserved ejection fraction: Comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol 2013;62:263-271
    • (2013) J Am Coll Cardiol , vol.62 , pp. 263-271
    • Paulus, W.J.1    Tschope, C.2
  • 62
    • 12944268866 scopus 로고    scopus 로고
    • Interactions between cardiac cells enhance cardiomyocyte hypertrophy and increase fibroblast proliferation
    • DOI 10.1002/jcp.20197
    • Fredj S, Bescond J, Louault C, Potreau D. Interactions between cardiac cells enhance cardiomyocyte hypertrophy and increase fibroblast proliferation. J Cell Physiol 2005; 202:891-899 (Pubitemid 40175867)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.3 , pp. 891-899
    • Fredj, S.1    Bescond, J.2    Louault, C.3    Potreau, D.4
  • 63
    • 24044458235 scopus 로고    scopus 로고
    • Combination of tumor necrosis factor-α ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice
    • DOI 10.1161/01.RES.0000178789.16929.cf
    • Kassiri Z, Oudit GY, Sanchez O, Dawood F, Mohammed FF, Nuttall RK, Edwards DR, Liu PP, Backx PH, Khokha R. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circ Res 2005;97:380-390 (Pubitemid 41216143)
    • (2005) Circulation Research , vol.97 , Issue.4 , pp. 380-390
    • Kassiri, Z.1    Oudit, G.Y.2    Sanchez, O.3    Dawood, F.4    Mohammed, F.F.5    Nuttall, R.K.6    Edwards, D.R.7    Liu, P.P.8    Backx, P.H.9    Khokha, R.10
  • 65
    • 79955031839 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: What are we talking about?
    • Baum J, Duffy HS. Fibroblasts and myofibroblasts: what are we talking about? J Cardiovasc Pharmacol 2011;57:376-379
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 376-379
    • Baum, J.1    Duffy, H.S.2
  • 66
    • 0029006974 scopus 로고
    • Collagens: Molecular biology, diseases, and potentials for therapy
    • Prockop DJ, Kivirikko KI. Collagens: Molecular biology, diseases, and potentials for therapy. Annu Rev Biochem 1995;64:403-434
    • (1995) Annu Rev Biochem , vol.64 , pp. 403-434
    • Prockop, D.J.1    Kivirikko, K.I.2
  • 67
    • 0347298758 scopus 로고    scopus 로고
    • PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1
    • DOI 10.1074/jbc.M209891200
    • Steiglitz BM, Keene DR, Greenspan DS. PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1. J Biol Chem 2002;277:49820-49830 (Pubitemid 36014430)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49820-49830
    • Steiglitz, B.M.1    Keene, D.R.2    Greenspan, D.S.3
  • 68
    • 84857235050 scopus 로고    scopus 로고
    • Diverse biological functions of the SPARC family of proteins
    • Bradshaw AD. Diverse biological functions of the SPARC family of proteins. Int J Biochem Cell Biol 2012;44:480-488
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 480-488
    • Bradshaw, A.D.1
  • 69
    • 84868338359 scopus 로고    scopus 로고
    • Time course of right ventricular pressure-overload induced myocardial fibrosis: Relationship to changes in fibroblast postsynthetic procollagen processing
    • Baicu CF, Li J, Zhang Y, Kasiganesan H, Cooper Gt, Zile MR, Bradshaw AD. Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing. Am J Physiol Heart Circ Physiol 2012;303:H1128-H1134
    • (2012) Am J Physiol Heart Circ Physiol , vol.303
    • Baicu, C.F.1    Li, J.2    Zhang, Y.3    Kasiganesan, H.4    Cooper, Gt.5    Zile, M.R.6    Bradshaw, A.D.7
  • 71
    • 35348852466 scopus 로고    scopus 로고
    • Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension
    • DOI 10.2353/ajpath.2007.061273
    • Socha MJ, Manhiani M, Said N, Imig JD, Motamed K. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. Am J Pathol 2007;171:1104-1112 (Pubitemid 47582886)
    • (2007) American Journal of Pathology , vol.171 , Issue.4 , pp. 1104-1112
    • Socha, M.J.1    Manhiani, M.2    Said, N.3    Imig, J.D.4    Motamed, K.5
  • 73
    • 34547575826 scopus 로고    scopus 로고
    • SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts
    • DOI 10.1074/jbc.M700167200
    • Rentz TJ, Poobalarahi F, Bornstein P, Sage EH, Bradshaw AD. SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. J Biol Chem 2007; 282:22062-22071 (Pubitemid 47195756)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.30 , pp. 22062-22071
    • Rentz, T.J.1    Poobalarahi, F.2    Bornstein, P.3    Sage, E.H.4    Bradshaw, A.D.5
  • 74
    • 0037791886 scopus 로고    scopus 로고
    • SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength
    • DOI 10.1046/j.1523-1747.2003.12241.x
    • Bradshaw AD, Puolakkainen P, Dasgupta J, Davidson JM, Wight TN, Helene Sage E. SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J Invest Dermatol 2003;120: 949-955 (Pubitemid 36702902)
    • (2003) Journal of Investigative Dermatology , vol.120 , Issue.6 , pp. 949-955
    • Bradshaw, A.D.1    Puolakkainen, P.2    Dasgupta, J.3    Davidson, J.M.4    Wight, T.N.5    Sage, E.H.6
  • 78
    • 50949117719 scopus 로고    scopus 로고
    • Osteopontin functions as an opsonin and facilitates phagocytosis by macrophages of hydroxyapatitecoated microspheres: Implications for bone wound healing
    • Pedraza CE, Nikolcheva LG, Kaartinen MT, Barralet JE, McKee MD. Osteopontin functions as an opsonin and facilitates phagocytosis by macrophages of hydroxyapatitecoated microspheres: implications for bone wound healing. Bone 2008;43:708-716
    • (2008) Bone , vol.43 , pp. 708-716
    • Pedraza, C.E.1    Nikolcheva, L.G.2    Kaartinen, M.T.3    Barralet, J.E.4    McKee, M.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.