Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts

Cardiovascular Research

Volumn 99, Issue 4, 2013, Pages 648-656

  Kötter, Sebastian ^a   Gout, Laurence ^b   Von Frieling Salewsky, Marion ^b   Müller, Anna Eliane ^a   Helling, Stefan ^b   Marcus, Katrin ^b   Dos Remedios, Cristobal ^c   Linke, Wolfgang A ^b   Krüger, Martina ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Connectin; Diastolic dysfunction; Myocardial stiffness; Passive tension; Phospho specific antibodies

Indexed keywords

CONNECTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; POLYCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ARTICLE; HEART FAILURE; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; MUSCLE RIGIDITY; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SARCOMERE LENGTH; WESTERN BLOTTING;

CONNECTIN; DIASTOLIC DYSFUNCTION; MYOCARDIAL STIFFNESS; PASSIVE TENSION; PHOSPHO-SPECIFIC ANTIBODIES;

AMINO ACID SEQUENCE; ANIMALS; CONNECTIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP-DEPENDENT PROTEIN KINASES; HEART FAILURE; HUMANS; MOLECULAR SEQUENCE DATA; MYOCYTES, CARDIAC; MYOFIBRILS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RATS;

EID: 84883221659     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt144     Document Type: Article

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