LORCASERIN;
NEW DRUG;
PHENTERMINE PLUS TOPIRAMATE;
PLACEBO;
QYSMIA;
TETRAHYDROLIPSTATIN;
UNCLASSIFIED DRUG;
ANTIOBESITY AGENT;
BENZAZEPINE DERIVATIVE;
DRUG DERIVATIVE;
FRUCTOSE;
PHENTERMINE;
TOPIRAMATE;
ANXIETY;
ATTENTION DISTURBANCE;
BODY MASS;
BODY WEIGHT;
CALORIE;
CREATININE BLOOD LEVEL;
DEPRESSION;
DRUG APPROVAL;
DRUG EFFICACY;
DRUG LABELING;
DRUG SAFETY;
EUPHORIA;
EXERCISE;
FOOD AND DRUG ADMINISTRATION;
HUMAN;
INSOMNIA;
LANGUAGE DISABILITY;
MEMORY DISORDER;
METABOLIC ACIDOSIS;
NEPHROTOXICITY;
OBESITY;
PHASE 3 CLINICAL TRIAL (TOPIC);
PRESCRIPTION;
PRIORITY JOURNAL;
RANDOMIZED CONTROLLED TRIAL (TOPIC);
REVIEW;
SYSTEMATIC REVIEW (TOPIC);
UNITED STATES;
VALVULAR HEART DISEASE;
WEIGHT REDUCTION;
ARTICLE;
DRUG EFFECT;
FEMALE;
MALE;
POSTMARKETING SURVEILLANCE;
ANTI-OBESITY AGENTS;
BENZAZEPINES;
FEMALE;
FRUCTOSE;
HUMANS;
MALE;
OBESITY;
PHENTERMINE;
PRODUCT SURVEILLANCE, POSTMARKETING;
RANDOMIZED CONTROLLED TRIALS AS TOPIC;
UNITED STATES;
UNITED STATES FOOD AND DRUG ADMINISTRATION;
WEIGHT LOSS;
US Dept of Health and Human Services; Centers for Disease Control and Prevention; National Center for Health Statistics. Accessed November 14 2013
US Dept of Health and Human Services; Centers for Disease Control and Prevention; National Center for Health Statistics. Health, United States, 2012: table 63, selected health conditions and risk factors. http://www.cdc.gov/nchs/ data/hus /hus12.pdf. Accessed November 14, 2013.
Perceived weight status, overweight diagnosis, and weight control among US adults: The NHANES 2003-2008 Study
Yaemsiri S, Slining MM, Agarwal SK. Perceived weight status, overweight diagnosis, and weight control among US adults: the NHANES 2003-2008 Study. Int J Obes (Lond). 2011;35(8):1063-1070.
Effect of diet and exercise, alone or combined, on weight and body composition in overweight-to-obese postmenopausal women
Foster-Schubert KE, Alfano CM, Duggan CR, et al. Effect of diet and exercise, alone or combined, on weight and body composition in overweight-to-obese postmenopausal women. Obesity (Silver Spring). 2012;20(8):1628-1638.
US Food and Drug Administration. Accessed November 15 2013
US Food and Drug Administration. Drug approval package: Belviq (lorcaserin hydrochloride tablets) (NDA) 022529. http://www.accessdata.fda.gov /drugsatfda-docs/nda/2012/022529Orig1s000TOC.cfm.AccessedNovember 15, 2013.
US Food and Drug Administration. Accessed November 15 2013
US Food and Drug Administration. Drug approval package: Qsymia (phentermine hydrochloride /topiramate) (NDA) 022580 http://www.accessdata.fda. gov/drugsatfda-docs/nda/2012 /022580Orig1s000-qsymia-toc.cfm. Accessed November 15, 2013.
Consumer Reports News. Making sense of Belviq's weight-loss claims. http://www.consumerreports.org/cro/news/2013/06 /making-sense-of-belviq-s- weight-loss-claims /index.htm. Accessed November 15, 2013.
US Department of Health and Human Services; Food and Drug Administration; Center for Drug Evaluation and Research (CDER): revision 1. Accessed November 15 2013
US Department of Health and Human Services; Food and Drug Administration; Center for Drug Evaluation and Research (CDER). Guidance for industry developing products for weight management: revision 1. http://www.fda.gov /downloads/Drugs/.../Guidances/ucm071612.pdf. Accessed November 15, 2013.
European Medicines Agency. Accessed January 10 2014
European Medicines Agency. Withdrawal of the marketing authorisation application for Belviq (lorcaserin) (EMA/309180/2013). http://www.ema.europa.eu/ docs/en-GB/document-library/Medicine -QA/2013/05/WC500143811.pdf. Accessed January 10, 2014.
European Medicines Agency. Accessed November 14 2013
European Medicines Agency. Refusal of the marketing authorisation forQsiva (phentermine /topiramate). http://www.ema.europa.eu/ema/index.jsp?curl= pages/medicines/human/medicines/002350/human-med-001607.jsp&mid= WC0b01ac058001d124. Accessed November 14, 2013.
Tran P, Thomas A. Summaryminutes of the Endocrinologic and Metabolic Drugs Advisory Committee meeting, March 28-29, 2012. http://www.fda.gov/ downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/ EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM303352.pdf. Accessed December 5, 2013.
Development times, clinical testing, postmarket follow-up, and safety risks for the new drugs approved by the US Food and Drug Administration: The class of 2008
doi:10.1001/jamainternmed.2013.11813
Moore TJ, Furberg CD. Development times, clinical testing, postmarket follow-up, and safety risks for the new drugs approved by the US Food and Drug Administration: the class of 2008. JAMA Intern Med. 2013. doi:10.1001/ jamainternmed.2013.11813.