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Volumn 9, Issue 7, 2014, Pages

Spermidine feeding decreases age-related locomotor activity loss and induces changes in lipid composition

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; PHOSPHOLIPID; SPERMIDINE; TRIACYLGLYCEROL; GLYCOGEN;

EID: 84904213406     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102435     Document Type: Article
Times cited : (41)

References (69)
  • 1
    • 77950200010 scopus 로고    scopus 로고
    • The genetics of ageing
    • Kenyon CJ (2010) The genetics of ageing. Nature 464: 504-512.
    • (2010) Nature , vol.464 , pp. 504-512
    • Kenyon, C.J.1
  • 2
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana L, Partridge L, Longo VD (2010) Extending healthy life span-from yeast to humans. Science 328: 321-326.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 3
    • 84866163081 scopus 로고    scopus 로고
    • Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
    • Mattison JA, Roth GS, Beasley TM, Tilmont EM, Handy AM, et al. (2012) Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 489: 318-321.
    • (2012) Nature , vol.489 , pp. 318-321
    • Mattison, J.A.1    Roth, G.S.2    Beasley, T.M.3    Tilmont, E.M.4    Handy, A.M.5
  • 5
    • 79951794971 scopus 로고    scopus 로고
    • Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
    • Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, et al. (2011) Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol 66: 191-201.
    • (2011) J Gerontol , vol.66 , pp. 191-201
    • Miller, R.A.1    Harrison, D.E.2    Astle, C.M.3    Baur, J.A.4    Boyd, A.R.5
  • 6
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, et al. (2009) Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460: 392-395.
    • (2009) Nature , vol.460 , pp. 392-395
    • Harrison, D.E.1    Strong, R.2    Sharp, Z.D.3    Nelson, J.F.4    Astle, C.M.5
  • 7
    • 72649091698 scopus 로고    scopus 로고
    • Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
    • Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, et al. (2010) Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab 11: 35-46.
    • (2010) Cell Metab , vol.11 , pp. 35-46
    • Bjedov, I.1    Toivonen, J.M.2    Kerr, F.3    Slack, C.4    Jacobson, J.5
  • 10
    • 32944470295 scopus 로고    scopus 로고
    • Decrease in polyamines with aging and their ingestion from food and drink
    • DOI 10.1093/jb/mvj003
    • Nishimura K, Shiina R, Kashiwagi K, Igarashi K (2006) Decrease in polyamines with aging and their ingestion from food and drink. J Biochem 139: 81-90. (Pubitemid 43258849)
    • (2006) Journal of Biochemistry , vol.139 , Issue.1 , pp. 81-90
    • Nishimura, K.1    Shiina, R.2    Kashiwagi, K.3    Igarashi, K.4
  • 11
    • 0021284677 scopus 로고
    • Polyamines in mammalian ageing: An oncological problem, too? A review
    • Scalabrin G, Ferioli ME (1984) Polyamines in mammalian ageing: an oncological problem, too? A review. Mech Ageing Dev 26: 149-164.
    • (1984) Mech Ageing Dev , vol.26 , pp. 149-164
    • Scalabrin, G.1    Ferioli, M.E.2
  • 14
    • 70350425215 scopus 로고    scopus 로고
    • Polyamine-rich food decreases age-associated pathology and mortality in aged mice
    • Soda K, Dobashi Y, Kano Y, Tsujinaka S, Konishi. (2009) Polyamine-rich food decreases age-associated pathology and mortality in aged mice. Exp Gerontol 44: 727-732.
    • (2009) Exp Gerontol , vol.44 , pp. 727-732
    • Soda, K.1    Dobashi, Y.2    Kano, Y.3    Tsujinaka, S.K.4
  • 15
    • 84870487733 scopus 로고    scopus 로고
    • Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways
    • Minois N, Carmona-Gutierrez D, Bauer MA, Rockenfeller P, Eisenberg T, et al. (2012) Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways. Cell Death Dis 3: e401.
    • (2012) Cell Death Dis , vol.3
    • Minois, N.1    Carmona-Gutierrez, D.2    Bauer, M.A.3    Rockenfeller, P.4    Eisenberg, T.5
  • 16
    • 0035447084 scopus 로고    scopus 로고
    • 1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice
    • DOI 10.1042/0264-6021:3580343
    • Suppola S, Heikkinen S, Parkkinen JJ, Uusi-Oukari M, Korhonen VP, et al. (2001) Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice. Biochem J 358: 343-348. (Pubitemid 32826350)
    • (2001) Biochemical Journal , vol.358 , Issue.2 , pp. 343-348
    • Suppola, S.1    Heikkinen, S.2    Parkkinen, J.J.3    Uusi-Oukari, M.4    Korhonen, V.-P.5    Keinanen, T.6    Alhonen, L.7    Janne, J.8
  • 17
    • 77950656808 scopus 로고    scopus 로고
    • Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
    • Morselli E, Galluzzi L, Kepp O, Criollo A, Maiuri MC, et al. (2009). Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol. Aging 1: 961-970.
    • (2009) Aging , vol.1 , pp. 961-970
    • Morselli, E.1    Galluzzi, L.2    Kepp, O.3    Criollo, A.4    Maiuri, M.C.5
  • 19
    • 83255164156 scopus 로고    scopus 로고
    • The role of autophagy in genetic pathways influencing ageing
    • Markaki M, Tavernarakis N (2011) The role of autophagy in genetic pathways influencing ageing. Biogerontol 12: 377-386.
    • (2011) Biogerontol , vol.12 , pp. 377-386
    • Markaki, M.1    Tavernarakis, N.2
  • 21
    • 34247140294 scopus 로고    scopus 로고
    • Role of insulin-like signalling in Drosophila lifespan
    • DOI 10.1016/j.tibs.2007.02.007, PII S0968000407000643
    • Giannakou ME, Partridge L (2007) Role of insulin-like signalling in Drosophila lifespan. Trends Biochem Sci 32: 180-188. (Pubitemid 46603282)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.4 , pp. 180-188
    • Giannakou, M.E.1    Partridge, L.2
  • 22
    • 77955747346 scopus 로고    scopus 로고
    • With TOR, less is more: A key role for the conserved nutrient-sensing TOR pathway in aging
    • Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, et al. (2010) With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 11: 453-465.
    • (2010) Cell Metab , vol.11 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3    Katewa, S.D.4    Li, P.W.5
  • 23
    • 33847259770 scopus 로고    scopus 로고
    • Regulation of Drosophila life span by olfaction and food-derived odors
    • DOI 10.1126/science.1136610
    • Libert S, Zwiener J, Chu X, Vanvoorhies V, Roman G, et al. (2007) Regulation of Drosophila life span by olfaction and food-derived odors. Science 315: 1133-1137. (Pubitemid 46328025)
    • (2007) Science , vol.315 , Issue.5815 , pp. 1133-1137
    • Libert, S.1    Zwiener, J.2    Chu, X.3    VanVoorhies, W.4    Roman, G.5    Pletcher, S.D.6
  • 24
    • 79959568125 scopus 로고    scopus 로고
    • Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. Elegans mutants
    • Shmookler Reis RJ, Xu L, Lee H, Chae M, Thaden JJ, et al. (2011) Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants. Aging 3: 125-144.
    • (2011) Aging , vol.3 , pp. 125-144
    • Shmookler Reis, R.J.1    Xu, L.2    Lee, H.3    Chae, M.4    Thaden, J.J.5
  • 25
    • 84874271499 scopus 로고    scopus 로고
    • ω-6 polyunsaturated fatty acids extend life span through the activation of autophagy
    • O'Rourke EJ, Kuballa P, Xavier R, Ruvkun G (2013) ω-6 polyunsaturated fatty acids extend life span through the activation of autophagy. Genes & Dvpt 27: 429-440.
    • (2013) Genes & Dvpt , vol.27 , pp. 429-440
    • O'Rourke, E.J.1    Kuballa, P.2    Xavier, R.3    Ruvkun, G.4
  • 26
    • 79960329362 scopus 로고    scopus 로고
    • Fat maintenance is a predictor of the murine lifespan response to dietary restriction
    • Liao CY, Rikke BA, Johnson TE, Gelfond JAL, Diaz V, et al. (2011) Fat maintenance is a predictor of the murine lifespan response to dietary restriction. Aging Cell 10: 629-639.
    • (2011) Aging Cell , vol.10 , pp. 629-639
    • Liao, C.Y.1    Rikke, B.A.2    Johnson, T.E.3    Gelfond, J.A.L.4    Diaz, V.5
  • 27
    • 84863514544 scopus 로고    scopus 로고
    • Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster
    • Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, et al. (2012) Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metab 16: 97-103.
    • (2012) Cell Metab , vol.16 , pp. 97-103
    • Katewa, S.D.1    Demontis, F.2    Kolipinski, M.3    Hubbard, A.4    Gill, M.S.5
  • 28
    • 77950406092 scopus 로고    scopus 로고
    • Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk
    • Slack C, Werz C, Wieser D, Alic N, Foley A, et al. (2010) Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. PLoS Genet 6: e1000881.
    • (2010) PLoS Genet , vol.6
    • Slack, C.1    Werz, C.2    Wieser, D.3    Alic, N.4    Foley, A.5
  • 29
    • 84903522116 scopus 로고    scopus 로고
    • Molecular basis of the "anti-aging" effect of spermidine and other natural polyamines - A mini review
    • doi:10.1159/000356748
    • Minois N (2014) Molecular basis of the "anti-aging" effect of spermidine and other natural polyamines - A mini review. Gerontol 60: doi:10.1159/000356748.
    • (2014) Gerontol , vol.60
    • Minois, N.1
  • 30
    • 0034704752 scopus 로고    scopus 로고
    • A Drosophila model of Parkinson's disease
    • DOI 10.1038/35006074
    • Feany MB, Bender WW (2000) A Drosophila model of Parkinson's disease. Nature 404: 394-398. (Pubitemid 30164341)
    • (2000) Nature , vol.404 , Issue.6776 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 31
    • 0034993183 scopus 로고    scopus 로고
    • Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70
    • DOI 10.1016/S0531-5565(00)00263-1, PII S0531556500002631
    • Minois N, Khazaeli AA, Curtsinger JW (2001) Locomotor activity as a function of age and life span in Drosophila melanogaster overexpressing hsp70. Exp Gerontol 36: 1137-1153. (Pubitemid 32515224)
    • (2001) Experimental Gerontology , vol.36 , Issue.7 , pp. 1137-1153
    • Minois, N.1    Khazaeli, A.A.2    Curtsinger, J.W.3
  • 32
    • 83455229641 scopus 로고    scopus 로고
    • Lipid changes in the aged brain: Effect on synaptic function and neuronal survival
    • Ledesm MD, Martin MG, Dotti CG (2012) Lipid changes in the aged brain: effect on synaptic function and neuronal survival. Prog Lipid Res 51: 23-25.
    • (2012) Prog Lipid Res , vol.51 , pp. 23-25
    • Ledesm, M.D.1    Martin, M.G.2    Dotti, C.G.3
  • 33
    • 80053312481 scopus 로고    scopus 로고
    • Autophagy and lipid metabolism coordinately modulate life span in germline-less C. Elegans
    • Lapierre LR, Gelino S, Meléndez A, Hansen M (2011) Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol 21: 1507-1514.
    • (2011) Curr Biol , vol.21 , pp. 1507-1514
    • Lapierre, L.R.1    Gelino, S.2    Meléndez, A.3    Hansen, M.4
  • 34
    • 84884878909 scopus 로고    scopus 로고
    • Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner
    • Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, et al. (2013) Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner. Nature Neurosci 16: 1453-1460.
    • (2013) Nature Neurosci , vol.16 , pp. 1453-1460
    • Gupta, V.K.1    Scheunemann, L.2    Eisenberg, T.3    Mertel, S.4    Bhukel, A.5
  • 35
    • 84890550000 scopus 로고    scopus 로고
    • Lipidomics in longevity and healthy aging
    • Doi:10.1007/s10522-013-9450-7
    • Gonzalez-Covarrubias V (2013) Lipidomics in longevity and healthy aging. Biogerontol Doi:10.1007/s10522-013-9450-7.
    • (2013) Biogerontol
    • Gonzalez-Covarrubias, V.1
  • 37
    • 84861657760 scopus 로고    scopus 로고
    • Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells
    • Ishii I, Ikeguchi Y, Mano H, Wada M, Pegg AE, et al. (2012) Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. Amino Acids 42: 619-626.
    • (2012) Amino Acids , vol.42 , pp. 619-626
    • Ishii, I.1    Ikeguchi, Y.2    Mano, H.3    Wada, M.4    Pegg, A.E.5
  • 38
    • 84880061760 scopus 로고    scopus 로고
    • Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HUR and PP2A
    • doi:10.1043/BJ20130263
    • Hyvönen MT, Koponen T, Weisell J, Pietilä M, Khomutov AR, et al. (2013) Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HUR and PP2A. Biochem J doi:10.1043/BJ20130263.
    • (2013) Biochem J
    • Hyvönen, M.T.1    Koponen, T.2    Weisell, J.3    Pietilä, M.4    Khomutov, A.R.5
  • 39
    • 84862796333 scopus 로고    scopus 로고
    • Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells
    • doi:10.1186/1423-0127-19-31
    • Choi YH, Park HY (2012) Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells. J Biomed Sci 19: doi:10.1186/1423-0127-19-31.
    • (2012) J Biomed Sci , vol.19
    • Choi, Y.H.1    Park, H.Y.2
  • 40
    • 84881596428 scopus 로고    scopus 로고
    • Metabolic profiling of Alzheimer's disease brains
    • doi:10.1038/srep02364
    • Inoue K, Tsutsui H, Akatsu H, Hashizume Y, Matsukawa N, et al. (2013) Metabolic profiling of Alzheimer's disease brains. Sci Rep 3: doi:10.1038/srep02364.
    • (2013) Sci Rep , vol.3
    • Inoue, K.1    Tsutsui, H.2    Akatsu, H.3    Hashizume, Y.4    Matsukawa, N.5
  • 41
    • 79952722882 scopus 로고    scopus 로고
    • Polyamines, androgens, and skeletal muscle hypertrophy
    • Lee NK, MacLean HE (2011) Polyamines, androgens, and skeletal muscle hypertrophy. J Cell Physiol 226: 1453-1460.
    • (2011) J Cell Physiol , vol.226 , pp. 1453-1460
    • Lee, N.K.1    MacLean, H.E.2
  • 42
    • 58149401702 scopus 로고    scopus 로고
    • Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation
    • Luchessi AD, Cambiaghi TD, Hirabara SM, Lambertucci RH, Silveira LR, et al. (2009) Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation. J Cell Physiol 218: 480-489.
    • (2009) J Cell Physiol , vol.218 , pp. 480-489
    • Luchessi, A.D.1    Cambiaghi, T.D.2    Hirabara, S.M.3    Lambertucci, R.H.4    Silveira, L.R.5
  • 44
    • 77954937345 scopus 로고    scopus 로고
    • SH2B regulation of growth, metabolism and longevity in both insects and mammals
    • Song W, Ren D, Li W, Jiang L, Cho KW, et al. (2010) SH2B regulation of growth, metabolism and longevity in both insects and mammals. Cell Metab 11: 427-437.
    • (2010) Cell Metab , vol.11 , pp. 427-437
    • Song, W.1    Ren, D.2    Li, W.3    Jiang, L.4    Cho, K.W.5
  • 45
  • 46
    • 84863318595 scopus 로고    scopus 로고
    • dSir2 deficiency in the fat body, but not muscles, affects systemic insulin signalling, fat mobilization and starvation survival in flies
    • Banerjee KK, Ayyub C, Sengupta S, Kolthur-Seetharam U (2012) dSir2 deficiency in the fat body, but not muscles, affects systemic insulin signalling, fat mobilization and starvation survival in flies. Aging 4: 206-223.
    • (2012) Aging , vol.4 , pp. 206-223
    • Banerjee, K.K.1    Ayyub, C.2    Sengupta, S.3    Kolthur-Seetharam, U.4
  • 47
    • 84867356065 scopus 로고    scopus 로고
    • Overexpression of fatty-acid-β-oxidation-related genes extends the lifespan of Drosophila melanogaster
    • Lee SH, Lee SK, Paik D, Min KJ (2012) Overexpression of fatty-acid-β-oxidation-related genes extends the lifespan of Drosophila melanogaster. Oxid Med Cell Longev 854502.
    • (2012) Oxid Med Cell Longev , pp. 854502
    • Lee, S.H.1    Lee, S.K.2    Paik, D.3    Min, K.J.4
  • 48
    • 84876097557 scopus 로고    scopus 로고
    • ArrayExpress update-trends in database growth and links to data analysis tools
    • Rustici G, Kolesnikov N, Brandizi M, Burdett T, Dylag M, et al. (2013) ArrayExpress update-trends in database growth and links to data analysis tools. Nucl Acids Res 41: D987-D990.
    • (2013) Nucl Acids Res , vol.41
    • Rustici, G.1    Kolesnikov, N.2    Brandizi, M.3    Burdett, T.4    Dylag, M.5
  • 50
  • 51
    • 84864833490 scopus 로고    scopus 로고
    • Effects of diet and development on the Drosophila lipidome
    • doi:10.1038/msb.2012.29
    • Carvalho M, Sampio JL, Palm W, Brakatschk M, Eaton S, et al. (2012) Effects of diet and development on the Drosophila lipidome. Mol Syst Biol 8: doi:10.1038/msb.2012.29.
    • (2012) Mol Syst Biol , vol.8
    • Carvalho, M.1    Sampio, J.L.2    Palm, W.3    Brakatschk, M.4    Eaton, S.5
  • 53
    • 79958769272 scopus 로고    scopus 로고
    • Lipid profiles of female and male Drosophila
    • doi:10.1186/1756-0500-4-198
    • Parisi M, Li R, Oliver B (2011) Lipid profiles of female and male Drosophila. BMC Res Notes 4: doi:10.1186/1756-0500-4-198.
    • (2011) BMC Res Notes , vol.4
    • Parisi, M.1    Li, R.2    Oliver, B.3
  • 54
    • 73449117508 scopus 로고    scopus 로고
    • Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
    • Baerga R, Zhang Y, Chen PH, Goldman S, Jin S (2009) Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy 5: 1118-1130.
    • (2009) Autophagy , vol.5 , pp. 1118-1130
    • Baerga, R.1    Zhang, Y.2    Chen, P.H.3    Goldman, S.J.S.4
  • 55
    • 73949124173 scopus 로고    scopus 로고
    • Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
    • Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, et al. (2009) Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci USA 106: 19860-19865.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19860-19865
    • Zhang, Y.1    Goldman, S.2    Baerga, R.3    Zhao, Y.4    Komatsu, M.5
  • 56
    • 70449448312 scopus 로고    scopus 로고
    • Autophagy regulates adipose mass and differentiation in mice
    • Singh R, Xiang Y, Wang Y, Baikati K, Cuervo AM, et al. (2009) Autophagy regulates adipose mass and differentiation in mice. J Clin Invest 119: 3329-3339.
    • (2009) J Clin Invest , vol.119 , pp. 3329-3339
    • Singh, R.1    Xiang, Y.2    Wang, Y.3    Baikati, K.4    Cuervo, A.M.5
  • 57
    • 79951889242 scopus 로고    scopus 로고
    • Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
    • Morselli E, Mariño G, Bennetzen MV, Eisenberg T, Megalou E, et al. (2011) Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol 192: 615-629.
    • (2011) J Cell Biol , vol.192 , pp. 615-629
    • Morselli, E.1    Mariño, G.2    Bennetzen, M.V.3    Eisenberg, T.4    Megalou, E.5
  • 58
    • 84860717549 scopus 로고    scopus 로고
    • Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers
    • Bennetzen MV, Marino G, Pultz D, Morselli E, Faergeman NJ, et al. (2012) Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers. Cell Cycle 11: 1827-1840.
    • (2012) Cell Cycle , vol.11 , pp. 1827-1840
    • Bennetzen, M.V.1    Marino, G.2    Pultz, D.3    Morselli, E.4    Faergeman, N.J.5
  • 59
    • 84874582747 scopus 로고    scopus 로고
    • Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth
    • Rajeeve V, Pearce W, Cascante M, Vanhaesebroeck B, Cutillas PR (2013) Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth. Biochem J 450: 619-628.
    • (2013) Biochem J , vol.450 , pp. 619-628
    • Rajeeve, V.1    Pearce, W.2    Cascante, M.3    Vanhaesebroeck, B.4    Cutillas, P.R.5
  • 60
    • 84862796333 scopus 로고    scopus 로고
    • Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells
    • doi:10.1186/1423-0127-19-31
    • Choi YH, Park HY (2012) Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells. J Biomed Sci doi:10.1186/1423-0127-19-31.
    • (2012) J Biomed Sci
    • Choi, Y.H.1    Park, H.Y.2
  • 61
    • 69249153394 scopus 로고    scopus 로고
    • A non-canonical MEK/ERK signalling pathway regulates autophagy via regulating Beclin 1
    • Wang J, Whiteman MW, Lian H, Wang G, Singh A, et al. (2009) A non-canonical MEK/ERK signalling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 284: 21412-21424.
    • (2009) J Biol Chem , vol.284 , pp. 21412-21424
    • Wang, J.1    Whiteman, M.W.2    Lian, H.3    Wang, G.4    Singh, A.5
  • 62
    • 79951857448 scopus 로고    scopus 로고
    • Protein kinase CK2 links polyamine metabolism to MAPK signalling in Drosophila
    • Stark F, Pfannstiel J, Klaiber I, Raabe T (2011) Protein kinase CK2 links polyamine metabolism to MAPK signalling in Drosophila. Cell Signal 23: 876-882.
    • (2011) Cell Signal , vol.23 , pp. 876-882
    • Stark, F.1    Pfannstiel, J.2    Klaiber, I.3    Raabe, T.4
  • 63
    • 84863437568 scopus 로고    scopus 로고
    • Spermidine affects the transcriptome responses to high temperature stress in ripening tomato fruit
    • Cheng L, Sun RR, Wang FY, Peng Z, Kong FL, et al. (2012) Spermidine affects the transcriptome responses to high temperature stress in ripening tomato fruit. J Zhejiang Univ Sci B 13: 283-297.
    • (2012) J Zhejiang Univ Sci B , vol.13 , pp. 283-297
    • Cheng, L.1    Sun, R.R.2    Wang, F.Y.3    Peng, Z.4    Kong, F.L.5
  • 64
    • 79955944455 scopus 로고    scopus 로고
    • Regulation of longevity by regulator of G-protein signalling protein
    • Lin YR, Kim K, Yang Y, Ivessa A, Sadoshima J, et al. (2011) Regulation of longevity by regulator of G-protein signalling protein, Loco. Aging Cell 10: 438-447.
    • (2011) Loco. Aging Cell , vol.10 , pp. 438-447
    • Lin, Y.R.1    Kim, K.2    Yang, Y.3    Ivessa, A.4    Sadoshima, J.5
  • 65
    • 79958830356 scopus 로고    scopus 로고
    • Loco signalling pathway in longevity
    • Lin YR, Parikh H, Park Y (2011) Loco signalling pathway in longevity. Small GTPases 2: 158-161.
    • (2011) Small GTPases , vol.2 , pp. 158-161
    • Lin, Y.R.1    Parikh, H.2    Park, Y.3
  • 66
    • 36849021043 scopus 로고    scopus 로고
    • Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
    • DOI 10.1101/gad.1600707
    • Juhász G, Érdi B, Sass M, Neufeld TP (2007) Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes & Dvpt 21: 3061-3066. (Pubitemid 350223523)
    • (2007) Genes and Development , vol.21 , Issue.23 , pp. 3061-3066
    • Juhasz, G.1    Erdi, B.2    Sass, M.3    Neufeld, T.P.4
  • 68
    • 77953489045 scopus 로고    scopus 로고
    • Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei
    • Richmond GS, Gibellini F, Young SA, Major L, Denton H, et al. (2010) Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei. Parasitol 137: 1357-1392.
    • (2010) Parasitol , vol.137 , pp. 1357-1392
    • Richmond, G.S.1    Gibellini, F.2    Young, S.A.3    Major, L.4    Denton, H.5
  • 69
    • 0013781097 scopus 로고
    • Microseparation of glycogen, sugars, and lipids
    • Van Handel E (1965) Microseparation of glycogen, sugars, and lipids. Anal Biochem 11: 266-271.
    • (1965) Anal Biochem , vol.11 , pp. 266-271
    • Van Handel, E.1


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