Polyamine production is downstream and upstream of oncogenic PI3K signalling and contributes to tumour cell growth

Biochemical Journal

Volumn 450, Issue 3, 2013, Pages 619-628

  Rajeeve, Vinothini ^a   Pearce, Wayne ^a   Cascante, Marta ^b   Vanhaesebroeck, Bart ^a   Cutillas, Pedro R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Cell signalling; Metabolite profiling; Phosphoinositide 3 kinase (PI3K); Phosphoproteomics; Polyamine

Indexed keywords

5' METHYLTHIOADENOSINE; ORNITHINE DECARBOXYLASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POLYAMINE; PROTEIN KINASE B; SPERMIDINE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DRUG MECHANISM; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PHOSPHORYLATION; POLYAMINE METABOLISM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANIMALS; CELL PROLIFERATION; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MASS SPECTROMETRY; METABOLOME; MICE; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; POLYAMINES; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 84874582747     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121525     Document Type: Article

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