Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport

Molecular Cancer Therapeutics

Volumn 13, Issue 7, 2014, Pages 1690-1703

  Kuzu, Omer F ^a   Gowda, Raghavendra ^a   Sharma, Arati ^a   Robertson, Gavin P ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; CHOLESTEROL; LEELAMINE; UNCLASSIFIED DRUG; DITERPENE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CANCER CELL; CELL COMPARTMENTALIZATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG ACTIVITY; ENDOCYTOSIS; ENDOSOME; HOMEOSTASIS; HUMAN; HUMAN CELL; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL DEATH; DRUG EFFECTS; GENETIC TRANSFECTION; HCT116 CELL LINE; KNOCKOUT MOUSE; MELANOMA; METABOLISM; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANIMALS; AUTOPHAGY; BIOLOGICAL TRANSPORT; CELL DEATH; CELL LINE, TUMOR; CHOLESTEROL; DITERPENES; ENDOCYTOSIS; HCT116 CELLS; HUMANS; MELANOMA; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TRANSFECTION;

EID: 84904202009     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0868     Document Type: Article

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