-
1
-
-
4944249657
-
Melanoma
-
Miller SJ, Maloney ME, editors. Malden, MA: Blackwell Science Inc.
-
Schalick WO, Albino AP, Reed JA, et al. Melanoma. In: Miller SJ, Maloney ME, editors. Cutaneous oncology: pathophysiology, diagnosis and management. Malden, MA: Blackwell Science Inc.; 1998. p. 180-348.
-
(1998)
Cutaneous Oncology: Pathophysiology, Diagnosis and Management
, pp. 180-348
-
-
Schalick, W.O.1
Albino, A.P.2
Reed, J.A.3
-
2
-
-
0035795581
-
Recent trends in cutaneous melanoma incidence among whites in the United States
-
Bethesda
-
Jemal A, Devesa SS, Hartge P, Tucker MA. Recent trends in cutaneous melanoma incidence among whites in the United States. J Natl Cancer Inst (Bethesda) 2001;93:678-83.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 678-683
-
-
Jemal, A.1
Devesa, S.S.2
Hartge, P.3
Tucker, M.A.4
-
4
-
-
0038793948
-
Apoptosis and melanoma chemoresistance
-
Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003; 22:3138-51.
-
(2003)
Oncogene
, vol.22
, pp. 3138-3151
-
-
Soengas, M.S.1
Lowe, S.W.2
-
5
-
-
0032944017
-
The chemoresistance of human malignant melanoma: An update
-
Serrone L, Hersey P. The chemoresistance of human malignant melanoma: an update. Melanoma Res 1999;9:51-8.
-
(1999)
Melanoma Res
, vol.9
, pp. 51-58
-
-
Serrone, L.1
Hersey, P.2
-
6
-
-
0035692448
-
Drug resistance in melanoma: Mechanisms, apoptosis, and new potential therapeutic targets
-
Grossman D, Altieri DC. Drug resistance in melanoma: mechanisms, apoptosis, and new potential therapeutic targets. Cancer Metastasis Rev 2001;20:3-11.
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 3-11
-
-
Grossman, D.1
Altieri, D.C.2
-
8
-
-
0037397144
-
Radiation therapy for malignant melanoma
-
Ballo MT, Ang KK. Radiation therapy for malignant melanoma. Surg Clin N Am 2003;83:323-42.
-
(2003)
Surg Clin N Am
, vol.83
, pp. 323-342
-
-
Ballo, M.T.1
Ang, K.K.2
-
9
-
-
0037280799
-
Adjuvant therapy for high-risk primary and resected metastatic melanoma
-
Hersey P. Adjuvant therapy for high-risk primary and resected metastatic melanoma. Intern Med J 2003;33:33-43.
-
(2003)
Intern Med J
, vol.33
, pp. 33-43
-
-
Hersey, P.1
-
10
-
-
0034124656
-
Dacarbazine-based chemotherapy for metastatic melanoma: Thirty-year experience overview
-
Serrone L, Zeuli M, Sega FM, Cognetti F. Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview. J Exp Clin Cancer Res 2000; 19:21-34.
-
(2000)
J Exp Clin Cancer Res
, vol.19
, pp. 21-34
-
-
Serrone, L.1
Zeuli, M.2
Sega, F.M.3
Cognetti, F.4
-
12
-
-
0038243115
-
Loss of PTEN promotes tumor development in malignant melanoma
-
Stahl JM, Cheung M, Sharma A, Trivedi NR, Shanmugam S, Robertson GP. Loss of PTEN promotes tumor development in malignant melanoma. Cancer Res 2003;63:2891-7.
-
(2003)
Cancer Res
, vol.63
, pp. 2891-2897
-
-
Stahl, J.M.1
Cheung, M.2
Sharma, A.3
Trivedi, N.R.4
Shanmugam, S.5
Robertson, G.P.6
-
13
-
-
0036849331
-
PKB binding proteins: Getting in on the Akt
-
Brazil DP, Park J, Hemmings BA. PKB binding proteins: getting in on the Akt. Cell 2002;111:293-303.
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
14
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
Nicholson KM, Anderson NG. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signalling 2002;14:381-95.
-
(2002)
Cell Signalling
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
15
-
-
0035448879
-
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
-
Chen WS, Xu PZ, Gottlob K, et al. Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev 2001;15:2203-8.
-
(2001)
Genes Dev
, vol.15
, pp. 2203-2208
-
-
Chen, W.S.1
Xu, P.Z.2
Gottlob, K.3
-
16
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB β)
-
Cho H, Mu J, Kim JK, et al. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB β). Science 2001;292:1728-31.
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
-
17
-
-
0035914388
-
Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H, Thorvaldsen JL, Chu Q, Feng F, Birnbaum MJ. Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem 2001;276:38349-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
18
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development and impeded adipogenesis in mice lacking Akt1 and Akt2
-
Peng XD, Xu PZ, Chen ML, et al. Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev 2003;17:1352-65.
-
(2003)
Genes Dev
, vol.17
, pp. 1352-1365
-
-
Peng, X.D.1
Xu, P.Z.2
Chen, M.L.3
-
19
-
-
0001582482
-
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: Amplification of AKT1 in a primary human gastric adenocarcinoma
-
Staal SP. Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. Proc Natl Acad Sci USA 1987;84:5034-7.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5034-5037
-
-
Staal, S.P.1
-
20
-
-
0026667730
-
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
-
Cheng JQ, Godwin AK, Bellacosa A, et al. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc Natl Acad Sci USA 1992;89:9267-71.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9267-9271
-
-
Cheng, J.Q.1
Godwin, A.K.2
Bellacosa, A.3
-
21
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
Cheng JQ, Ruggeri B, Klein WM, et al. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci USA 1996;93:3636-41.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
-
22
-
-
17644444873
-
Multiple gene alterations involved in the processor of human gastric carcinogenesis
-
Lu Y, Li Z, Sun M. Multiple gene alterations involved in the processor of human gastric carcinogenesis. Chung-Hua i Hsueh Tsa Chih 1995;75:679-82.
-
(1995)
Chung-Hua I Hsueh Tsa Chih
, vol.75
, pp. 679-682
-
-
Lu, Y.1
Li, Z.2
Sun, M.3
-
23
-
-
0029127042
-
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
-
Bellacosa A, de Feo D, Godwin AK, et al. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int J Cancer 1995;64:280-5.
-
(1995)
Int J Cancer
, vol.64
, pp. 280-285
-
-
Bellacosa, A.1
De Feo, D.2
Godwin, A.K.3
-
24
-
-
0033082460
-
Comparative genomic hybridization of cancer of the gastroesophageal junction: Deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas
-
van Dekken H, Geelen E, Dinjens WN, et al. Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas. Cancer Res 1999;59:748-52.
-
(1999)
Cancer Res
, vol.59
, pp. 748-752
-
-
Van Dekken, H.1
Geelen, E.2
Dinjens, W.N.3
-
25
-
-
0034880946
-
Mutations of the activation-associated phosphorylation sites at codons 308 and 473 of protein kinase B are absent in human melanoma
-
Waldmann V, Wacker J, Deichmann M. Mutations of the activation-associated phosphorylation sites at codons 308 and 473 of protein kinase B are absent in human melanoma. Arch Dermatol Res 2001;293:368-72.
-
(2001)
Arch Dermatol Res
, vol.293
, pp. 368-372
-
-
Waldmann, V.1
Wacker, J.2
Deichmann, M.3
-
26
-
-
0036189577
-
Absence of mutations in the pleckstrin homology (PH) domain of protein kinase B (PKB/Akt) in malignant melanoma
-
Waldmann V, Wacker J, Deichmann M. Absence of mutations in the pleckstrin homology (PH) domain of protein kinase B (PKB/Akt) in malignant melanoma. Melanoma Res 2002;12:45-50.
-
(2002)
Melanoma Res
, vol.12
, pp. 45-50
-
-
Waldmann, V.1
Wacker, J.2
Deichmann, M.3
-
27
-
-
0032931508
-
Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells
-
Krasilnikov M, Adler V, Fuchs SY, et al. Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells. Mol Carcinog 1999;24:64-9.
-
(1999)
Mol Carcinog
, vol.24
, pp. 64-69
-
-
Krasilnikov, M.1
Adler, V.2
Fuchs, S.Y.3
-
28
-
-
0037115394
-
Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-κB and tumor progression
-
Dhawan P, Singh AB, Ellis DL, Richmond A. Constitutive activation of Akt/protein kinase B in melanoma leads to up-regulation of nuclear factor-κB and tumor progression. Cancer Res 2002;62:7335-42.
-
(2002)
Cancer Res
, vol.62
, pp. 7335-7342
-
-
Dhawan, P.1
Singh, A.B.2
Ellis, D.L.3
Richmond, A.4
-
29
-
-
0034742120
-
AKT1/PKBα kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
-
Sun M, Wang G, Paciga JE, et al. AKT1/PKBα kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol 2001;159:431-7.
-
(2001)
Am J Pathol
, vol.159
, pp. 431-437
-
-
Sun, M.1
Wang, G.2
Paciga, J.E.3
-
30
-
-
0032531274
-
Translocation and activation of AKT2 in response to stimulation by insulin
-
Mitsuuchi Y, Johnson SW, Moonblatt S, Testa JR. Translocation and activation of AKT2 in response to stimulation by insulin. J Cell Biochem 1998;70:433-41.
-
(1998)
J Cell Biochem
, vol.70
, pp. 433-441
-
-
Mitsuuchi, Y.1
Johnson, S.W.2
Moonblatt, S.3
Testa, J.R.4
-
31
-
-
0033515625
-
A human protein kinase Bγ with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain
-
Brodbeck D, Cron P, Hemmings BA. A human protein kinase Bγ with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain. J Biol Chem 1999;274:9133-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 9133-9136
-
-
Brodbeck, D.1
Cron, P.2
Hemmings, B.A.3
-
32
-
-
0001278782
-
Melanoma: The Wistar (WM) cell lines
-
Masters JRW, Palsson B, editors. London, Great Britain: Kluwer Academic Publishers
-
Hsu M-Y, Elder DE, Herlyn M. Melanoma: the Wistar (WM) cell lines. In: Masters JRW, Palsson B, editors. Human cell culture, vol. I. London, Great Britain: Kluwer Academic Publishers; 1999. p. 259-74.
-
(1999)
Human Cell Culture
, vol.1
, pp. 259-274
-
-
Hsu, M.-Y.1
Elder, D.E.2
Herlyn, M.3
-
34
-
-
0032523833
-
Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization
-
Bastian BC, LeBoit PE, Hamm H, Brocker EB, Pinkel D. Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization. Cancer Res 1998;58:2170-5.
-
(1998)
Cancer Res
, vol.58
, pp. 2170-2175
-
-
Bastian, B.C.1
Leboit, P.E.2
Hamm, H.3
Brocker, E.B.4
Pinkel, D.5
-
35
-
-
0029148164
-
Cytogenetics of 158 patients with regional or disseminated melanoma: Subset analysis of near-diploid and simple karyotypes
-
Thompson FH, Emerson J, Olson S, et al. Cytogenetics of 158 patients with regional or disseminated melanoma: subset analysis of near-diploid and simple karyotypes. Cancer Genet Cytogenet 1995;83:93-104.
-
(1995)
Cancer Genet Cytogenet
, vol.83
, pp. 93-104
-
-
Thompson, F.H.1
Emerson, J.2
Olson, S.3
-
36
-
-
0030825508
-
Chromosomal imbalance maps of malignant solid tumors: A cytogenetic survey of 3185 neoplasms
-
Mertens F, Johansson B, Höglund M, Mitelman F. Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 1997; 57:2765-80.
-
(1997)
Cancer Res
, vol.57
, pp. 2765-2780
-
-
Mertens, F.1
Johansson, B.2
Höglund, M.3
Mitelman, F.4
-
37
-
-
0033178724
-
The chromosome 10 monosomy common in human melanomas results from loss of two separate tumor suppressor loci
-
Robertson GP, Herbst RA, Nagane M, Huang HJ, Cavenee WK. The chromosome 10 monosomy common in human melanomas results from loss of two separate tumor suppressor loci. Cancer Res 1999;59:3596-601.
-
(1999)
Cancer Res
, vol.59
, pp. 3596-3601
-
-
Robertson, G.P.1
Herbst, R.A.2
Nagane, M.3
Huang, H.J.4
Cavenee, W.K.5
-
38
-
-
0023889925
-
Possible involvement of the chromosome region 10q24-q26 in early stages of melanocytic neoplasia
-
Parmiter AH, Balaban G, Clark WH Jr, Nowell PC. Possible involvement of the chromosome region 10q24-q26 in early stages of melanocytic neoplasia. Cancer Genet Cytogenet 1988;30:313-7.
-
(1988)
Cancer Genet Cytogenet
, vol.30
, pp. 313-317
-
-
Parmiter, A.H.1
Balaban, G.2
Clark Jr., W.H.3
Nowell, P.C.4
-
39
-
-
0142091454
-
Ceramide disables 3-phosphoinoside binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCζ-dependent mechanism
-
Powell DJ, Hajduch E, Kular G, Hundal HS. Ceramide disables 3-phosphoinoside binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCζ-dependent mechanism. Mol Cell Biol 2003;23:7794-808.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
Hundal, H.S.4
-
40
-
-
0036479208
-
Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family
-
Laine J, Kunstle G, Obata T, Noguchi M. Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family. J Biol Chem 2002;277:3743-51.
-
(2002)
J Biol Chem
, vol.277
, pp. 3743-3751
-
-
Laine, J.1
Kunstle, G.2
Obata, T.3
Noguchi, M.4
-
41
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002;108:153-64.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
|