A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Nature Communications

Volumn 5, Issue , 2014, Pages

  Bende, Niraj S ^a   Dziemborowicz, SłAwomir ^b   Mobli, Mehdi ^a   Herzig, Volker ^a   Gilchrist, John ^c   Wagner, Jordan ^c   Nicholson, Graham M ^b   King, Glenn F ^a   Bosmans, Frank ^c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SPIDER TOXIN DC1A; SPIDER VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; INSECTICIDE;

BIOCHEMISTRY; BIOPESTICIDE; COCKROACH; CONCENTRATION (COMPOSITION); GENE EXPRESSION; INSECT; MUTATION; SENSOR; SODIUM; SPIDER; TOXIN; VULNERABILITY;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; BLATTELLA GERMANICA; CONFORMATION; CYTOPLASM; DISULFIDE BOND; GENE LOCUS; HOUSE FLY; INSECT; INSECTICIDAL ACTIVITY; ION CURRENT; LIPID BILAYER; LUCILIA CUPRINA; MEMBRANE DEPOLARIZATION; MOTOR ACTIVITY; NONHUMAN; PERIPLANETA AMERICANA; REPOLARIZATION; SEQUENCE ALIGNMENT; SODIUM CURRENT; STEADY STATE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; COCKROACH; DRUG EFFECTS; MOLECULAR GENETICS; PHYSIOLOGY; SPECIES DIFFERENCE; SPIDER;

AMINO ACID SEQUENCE; ANIMALS; COCKROACHES; INSECTICIDES; MOLECULAR SEQUENCE DATA; SPECIES SPECIFICITY; SPIDER VENOMS; SPIDERS; VOLTAGE-GATED SODIUM CHANNELS;

EID: 84904173537     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5350     Document Type: Article

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