Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels

Journal of Biological Chemistry

Volumn 286, Issue 38, 2011, Pages 33641-33651

  Zhang, Joel Z ^a   Yarov Yarovoy, Vladimir ^a,c   Scheuer, Todd ^a   Karbat, Izhar ^b   Cohen, Lior ^b   Gordon, Dalia ^b   Gurevitz, Michael ^b   Catterall, William A ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; BIDIRECTIONAL EFFECTS; BINDING AFFINITIES; BINDING PARTNERS; EXTRACELLULAR; EXTRACELLULAR LOOPS; HIGH RESOLUTION; HOT SPOT; KEY BINDING; MEMBRANE POTENTIALS; MODELING SYSTEMS; MOLECULAR DETERMINANTS; MOLECULAR INSIGHTS; MOLECULAR MODELS; MOLECULAR TARGETS; RAT BRAIN; RECEPTOR SITES; SODIUM CHANNEL; TOXIN AFFINITY; TOXIN EFFECTS; VOLTAGE DEPENDENCE; VOLTAGE SENSOR;

AMINO ACIDS; BINDING ENERGY; METABOLITES; SENSORS; SODIUM;

TOXIC MATERIALS;

BETA SCORPION TOXIN; GLUTAMIC ACID; GLYCINE; PROLINE; SCORPION VENOM; SODIUM CHANNEL NAV1.2; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; CONTROLLED STUDY; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; RAT; SENSOR;

ANIMALS; ION CHANNEL GATING; MODELS, MOLECULAR; MUTANT PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, CELL SURFACE; SCORPION VENOMS; SODIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP;

RATTUS; SCORPIONES;

EID: 80053013648     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.282509     Document Type: Article

References (43)

1. Hille, B. (2001) Ion Channels of Excitable Membranes, 3 Ed., Sinauer, Sunderland, MA
2. Catterall, W. A. (2000) Neuron 26, 13-25
3. Yarov-Yarovoy, V., Baker, D., and Catterall, W. A. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 7292-7297
4. Catterall, W. A., Cestèle, S., Yarov-Yarovoy, V., Yu, F. H., Konoki, K., and Scheuer, T. (2007) Toxicon 49, 124-141
5. Cahalan, M. D. (1975) J. Physiol. 244, 511-534
6. Couraud, F., Jover, E., Dubois, J. M., and Rochat, H. (1982) Toxicon 20, 9-16
7. Gurevitz, M., Karbat, I., Cohen, L., Ilan, N., Kahn, R., Turkov, M., Stankiewicz, M., Stühmer, W., Dong, K., and Gordon, D. (2007) Toxicon 49, 473-489
8. Cestèle, S., Qu, Y., Rogers, J. C., Rochat, H., Scheuer, T., and Catterall, W. A. (1998) Neuron 21, 919-931
9. Cestèle, S., Yarov-Yarovoy, V., Qu, Y., Sampieri, F., Scheuer, T., and Catterall, W. A. (2006) J. Biol. Chem. 281, 21332-21344
10. Cestèle, S., Scheuer, T., Mantegazza, M., Rochat, H., and Catterall, W. A. (2001) J. Gen. Physiol. 118, 291-302
11. Marcotte, P., Chen, L. Q., Kallen, R. G., and Chahine, M. (1997) Circ. Res. 80, 363-369
12. Yarov-Yarovoy, V., Schonbrun, J., and Baker, D. (2006) Proteins 62, 1010-1025
13. Long, S. B., Tao, X., Campbell, E. B., and MacKinnon, R. (2007) Nature 450, 376-382
14. Jeanmougin, F., Thompson, J. D., Gouy, M., Higgins, D. G., and Gibson, T. J. (1998) Trends Biochem. Sci. 23, 403-405
15. Rohl, C. A., Strauss, C. E., Misura, K. M., and Baker, D. (2004) Methods Enzymol. 383, 66-93
16. Gray, J. J., Moughon, S., Wang, C., Schueler-Furman, O., Kuhlman, B., Rohl, C. A., and Baker, D. (2003) J. Mol. Biol. 331, 281-299
17. Wang, C., Bradley, P., and Baker, D. (2007) J. Mol. Biol. 373, 503-519
18. Cohen, L., Karbat, I., Gilles, N., Ilan, N., Benveniste, M., Gordon, D., and Gurevitz, M. (2005) J. Biol. Chem. 280, 5045-5053
19. Karbat, I., Ilan, N., Zhang, J. Z., Cohen, L., Kahn, R., Benveniste, M., Scheuer, T., Catterall, W. A., Gordon, D., and Gurevitz, M. (2010) J. Biol. Chem. 285, 30531-30538
20. Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B. T., and MacKinnon, R. (2003) Nature 423, 33-41
21. Cohen, L., Ilan, N., Gur, M., Stühmer, W., Gordon, D., and Gurevitz, M. (2007) J. Biol. Chem. 282, 29424-29430
22. Ruta, V., Chen, J., and MacKinnon, R. (2005) Cell 123, 463-475
23. Banerjee, A., and MacKinnon, R. (2008) J. Mol. Biol. 381, 569-580
24. Pathak, M. M., Yarov-Yarovoy, V., Agarwal, G., Roux, B., Barth, P., Kohout, S., Tombola, F., and Isacoff, E. Y. (2007) Neuron 56, 124-140
25. DeCaen, P. G., Yarov-Yarovoy, V., Zhao, Y., Scheuer, T., and Catterall, W. A. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 15142-15147
26. DeCaen, P. G., Yarov-Yarovoy, V., Sharp, E. M., Scheuer, T., and Catterall, W. A. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 22498-22503
27. Bosmans, F., Martin-Eauclaire, M. F., and Swartz, K. J. (2008) Nature 456, 202-208
28. Mantegazza, M., and Cestèle, S. (2005) J. Physiol. 568, 13-30
29. Xiao, Y., Bingham, J. P., Zhu, W., Moczydlowski, E., Liang, S., and Cummins, T. R. (2008) J. Biol. Chem. 283, 27300-27313
30. Campos, F. V., Chanda, B., Beirão, P. S., and Bezanilla, F. (2007) J. Gen. Physiol. 130, 257-268
31. Smith, J. J., Cummins, T. R., Alphy, S., and Blumenthal, K. M. (2007) J. Biol. Chem. 282, 12687-12697
32. Sokolov, S., Kraus, R. L., Scheuer, T., and Catterall, W. A. (2008) Mol. Pharmacol. 73, 1020-1028
33. Campos, F. V., Chanda, B., Beirão, P. S., and Bezanilla, F. (2008) J. Gen. Physiol. 132, 251-263
34. Rogers, J. C., Qu, Y., Tanada, T. N., Scheuer, T., and Catterall, W. A. (1996) J. Biol. Chem. 271, 15950-15962
35. Leipold, E., Hansel, A., Olivera, B. M., Terlau, H., and Heinemann, S. H. (2005) FEBS Lett. 579, 3881-3884
36. Swartz, K. J., and MacKinnon, R. (1997) Neuron 18, 675-682
37. Phillips, L. R., Milescu, M., Li-Smerin, Y., Mindell, J. A., Kim, J. I., and Swartz, K. J. (2005) Nature 436, 857-860
38. Milescu, M., Vobecky, J., Roh, S. H., Kim, S. H., Jung, H. J., Kim, J. I., and Swartz, K. J. (2007) J. Gen. Physiol. 130, 497-511
39. Cohen, L., Gilles, N., Karbat, I., Ilan, N., Gordon, D., and Gurevitz, M. (2006) J. Biol. Chem. 281, 20673-20679
40. Catterall, W. A. (1986) Annu. Rev. Biochem. 55, 953-985
41. Guy, H. R., and Seetharamulu, P. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 508-512
42. Catterall, W. A. (2010) Neuron 67, 915-928
43. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) J. Comput. Chem. 25, 1605-1612