메뉴 건너뛰기




Volumn 133, Issue 5, 2009, Pages 467-483

A single charged voltage sensor is capable of gating the Shaker K + channel

Author keywords

[No Author keywords available]

Indexed keywords

SHAKER POTASSIUM CHANNEL;

EID: 66049159090     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200810082     Document Type: Article
Times cited : (49)

References (69)
  • 1
    • 0030175348 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1016/S0896-6273(00)80143-9
    • Aggarwal, S.K., and R. MacKinnon. 1996. Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron. 16:1169-1177. (Pubitemid 26227238)
    • (1996) Neuron , vol.16 , Issue.6 , pp. 1169-1177
    • Aggarwal, S.K.1    MacKinnon, R.2
  • 2
    • 0014607213 scopus 로고
    • Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons
    • Armstrong, C.M. 1969. Inactivation of the potassium conductance and related phenomena caused by quaternary ammonium ion injection in squid axons. J. Gen. Physiol. 54:553-575.
    • (1969) J. Gen. Physiol. , vol.54 , pp. 553-575
    • Armstrong, C.M.1
  • 3
    • 0032920625 scopus 로고    scopus 로고
    • Voltage-insensitive gating after charge-neutralizing mutations in the S4 segment of Shaker channels
    • DOI 10.1085/jgp.113.1.139
    • Bao, H., A. Hakeem, M. Henteleff, J.G. Starkus, and M.D. Rayner. 1999. Voltage-insensitive gating after charge-neutralizing mutations in the S4 segment of Shaker channels. J. Gen. Physiol. 113:139-151. (Pubitemid 29051253)
    • (1999) Journal of General Physiology , vol.113 , Issue.1 , pp. 139-151
    • Bao, H.1    Hakeem, A.2    Henteleff, M.3    Starkus, J.G.4    Rayner, M.D.5
  • 5
    • 0028213205 scopus 로고
    • + channels: II. the components of gating currents and a model of channel activation
    • Bezanilla, F., E. Perozo, and E. Stefani. 1994. Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys. J. 66:1011-1021. (Pubitemid 24106347)
    • (1994) Biophysical Journal , vol.66 , Issue.4 , pp. 1011-1021
    • Bezanilla, F.1    Perozo, E.2    Stefani, E.3
  • 7
    • 0031697562 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1085/jgp.112.4.391
    • Cha, A., and F. Bezanilla. 1998. Structural implications of fluorescence quenching in the Shaker K+ channel. J. Gen. Physiol. 112:391-408. (Pubitemid 28467597)
    • (1998) Journal of General Physiology , vol.112 , Issue.4 , pp. 391-408
    • Cha, A.1    Bezanilla, F.2
  • 8
    • 23744511543 scopus 로고    scopus 로고
    • K channel subconductance levels result from heteromeric pore conformations
    • DOI 10.1085/jgp.200509253
    • Chapman, M.L., and A.M. VanDongen. 2005. K channel subconductance levels result from heteromeric pore conformations. J. Gen. Physiol. 126:87-103. (Pubitemid 41124187)
    • (2005) Journal of General Physiology , vol.126 , Issue.2 , pp. 87-103
    • Chapman, M.L.1    Vandongen, A.M.J.2
  • 9
    • 0031022168 scopus 로고    scopus 로고
    • Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating
    • Chapman, M.L., H.M. VanDongen, and A.M. VanDongen. 1997. Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating. Biophys. J. 72:708-719. (Pubitemid 27044878)
    • (1997) Biophysical Journal , vol.72 , Issue.2 I , pp. 708-719
    • Chapman, M.L.1    Vandongen, H.M.A.2    Vandongen, A.M.J.3
  • 10
    • 0002415827 scopus 로고
    • Potassium ion current in the squid giant axon: Dynamic characteristic
    • Cole, K.S., and J.W. Moore. 1960. Potassium ion current in the squid giant axon: dynamic characteristic. Biophys. J. 1:1-14.
    • (1960) Biophys. J. , vol.1 , pp. 1-14
    • Cole, K.S.1    Moore, J.W.2
  • 11
    • 0032866866 scopus 로고    scopus 로고
    • Role of individual surface charges of voltage-gated K channels
    • Elinder, F., and P. Arhem. 1999. Role of individual surface charges of voltage-gated K channels. Biophys. J. 77:1358-1362. (Pubitemid 29407309)
    • (1999) Biophysical Journal , vol.77 , Issue.3 , pp. 1358-1362
    • Blinder, F.1    Arhem, P.2
  • 12
    • 0343471377 scopus 로고    scopus 로고
    • Modification of a PCR-based site-directed mutagenesis method
    • Fisher, C.L., and G.K. Pei. 1997. Modification of a PCR-based site-directed mutagenesis method. Biotechniques. 23:570-571, 574. (Pubitemid 27450899)
    • (1997) BioTechniques , vol.23 , Issue.4 , pp. 570-574
    • Fisher, C.L.1    Pei, G.K.2
  • 13
    • 0005979454 scopus 로고
    • A kinetic model of the conductance changes in nerve membrane
    • Fitzhugh, R. 1965. A kinetic model of the conductance changes in nerve membrane. J. Cell. Comp. Physiol. 66:111-118.
    • (1965) J. Cell. Comp. Physiol. , vol.66 , pp. 111-118
    • Fitzhugh, R.1
  • 14
    • 0027484056 scopus 로고
    • + channel
    • Heginbotham, L., and R. MacKinnon. 1993. Conduction properties of the cloned Shaker K+ channel. Biophys. J. 65:2089-2096. (Pubitemid 23334876)
    • (1993) Biophysical Journal , vol.65 , Issue.5 , pp. 2089-2096
    • Heginbotham, L.1    MacKinnon, R.2
  • 15
    • 77956707015 scopus 로고
    • Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
    • Hodgkin, A.L., and A.F. Huxley. 1952a. Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. J. Physiol. 116:449-472.
    • (1952) J. Physiol. , vol.116 , pp. 449-472
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 16
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • Hodgkin, A.L., and A.F. Huxley. 1952b. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117:500-544.
    • (1952) J. Physiol. , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 17
    • 0030956162 scopus 로고    scopus 로고
    • + channels: Evidence for a trap door mechanism of activation gating
    • DOI 10.1085/jgp.109.5.527
    • Holmgren, M., P.L. Smith, and G. Yellen. 1997. Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating. J. Gen. Physiol. 109:527-535. (Pubitemid 27212377)
    • (1997) Journal of General Physiology , vol.109 , Issue.5 , pp. 527-535
    • Holmgren, M.1    Smith, P.L.2    Yellen, G.3
  • 18
    • 0032168179 scopus 로고    scopus 로고
    • + channel can be trapped in the open state by an intersubunit metal bridge
    • DOI 10.1016/S0896-6273(00)80571-1
    • Holmgren, M., K.S. Shin, and G. Yellen. 1998. The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge. Neuron. 21:617-621. (Pubitemid 28475512)
    • (1998) Neuron , vol.21 , Issue.3 , pp. 617-621
    • Holmgren, M.1    Shin, K.S.2    Yellen, G.3
  • 19
    • 0033811116 scopus 로고    scopus 로고
    • Immobilizing the moving parts of voltage-gated ion channels
    • Horn, R., S. Ding, and H.J. Gruber. 2000. Immobilizing the moving parts of voltage-gated ion channels. J. Gen. Physiol. 116:461-476.
    • (2000) J. Gen. Physiol. , vol.116 , pp. 461-476
    • Horn, R.1    Ding, S.2    Gruber, H.J.3
  • 20
    • 0025224223 scopus 로고
    • Biophysical and molecular mechanisms of Shaker potassium channel inactivation
    • Hoshi, T., W.N. Zagotta, and R.W. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:533-538. (Pubitemid 120031778)
    • (1990) Science , vol.250 , Issue.4980 , pp. 533-538
    • Hoshi, T.1    Zagotta, W.N.2    Aldrich, R.W.3
  • 21
    • 0028014591 scopus 로고
    • Shaker potassium channel gating I: Transitions near the open state
    • Hoshi, T., W.N. Zagotta, and R.W. Aldrich. 1994. Shaker potassium channel gating. I: transitions near the open state. J. Gen. Physiol. 103:249-278. (Pubitemid 24068560)
    • (1994) Journal of General Physiology , vol.103 , Issue.2 , pp. 249-278
    • Hoshi, T.1    Zagotta, W.N.2    Aldrich, R.W.3
  • 22
    • 0027078418 scopus 로고
    • Cooperative interactions among subunits of a voltage-dependent potassium channel. Evidence from expression of concatenated cDNAs
    • Hurst, R.S., M.P. Kavanaugh, J. Yakel, J.P. Adelman, and R.A. North. 1992. Cooperative interactions among subunits of a voltage-dependent potassium channel. Evidence from expression of concatenated cDNAs. J. Biol. Chem. 267:23742-23745. (Pubitemid 23088180)
    • (1992) Journal of Biological Chemistry , vol.267 , Issue.33 , pp. 23742-23745
    • Hurst, R.S.1    Kavanaugh, M.P.2    Yakel, J.3    Adelman, J.P.4    North, R.A.5
  • 23
    • 0025362581 scopus 로고
    • Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes
    • DOI 10.1038/345530a0
    • Isacoff, E.Y., Y.N. Jan, and L.Y. Jan. 1990. Evidence for the formation of heteromultimeric potassium channels in Xenopus oocytes. Nature. 345:530-534. (Pubitemid 20178907)
    • (1990) Nature , vol.345 , Issue.6275 , pp. 530-534
    • Isacoff, E.Y.1    Jan, Y.N.2    Jan, L.Y.3
  • 24
    • 0026533326 scopus 로고
    • Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethyl-ammonium
    • Kavanaugh, M.P., R.S. Hurst, J. Yakel, M.D. Varnum, J.P. Adelman, and R.A. North. 1992. Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethyl-ammonium. Neuron. 8:493-497.
    • (1992) Neuron , vol.8 , pp. 493-497
    • Kavanaugh, M.P.1    Hurst, R.S.2    Yakel, J.3    Varnum, M.D.4    Adelman, J.P.5    North, R.A.6
  • 25
    • 0031811940 scopus 로고    scopus 로고
    • Activation kinetics of the delayed rectifier potassium current of bullfrog sympathetic neurons
    • Klemic, K.G., D.M. Durand, and S.W. Jones. 1998. Activation kinetics of the delayed rectifier potassium current of bullfrog sympathetic neurons. J. Neurophysiol. 79:2345-2357. (Pubitemid 28261623)
    • (1998) Journal of Neurophysiology , vol.79 , Issue.5 , pp. 2345-2357
    • Klemic, K.G.1    Durand, D.M.2    Jones, S.W.3
  • 26
    • 0031030226 scopus 로고    scopus 로고
    • + channel pore
    • Krovetz, H.S., H.M. VanDongen, and A.M. VanDongen. 1997. Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore. Biophys. J. 72:117-126. (Pubitemid 27043422)
    • (1997) Biophysical Journal , vol.72 , Issue.1 , pp. 117-126
    • Krovetz, H.S.1    Vandongen, H.M.A.2    Vandongen, A.M.J.3
  • 27
    • 33745216690 scopus 로고    scopus 로고
    • A structural interpretation of voltage-gated potassium channel inactivation
    • DOI 10.1016/j.pbiomolbio.2005.10.001, PII S0079610705000635
    • Kurata, H.T., and D. Fedida. 2006. A structural interpretation of voltage-gated potassium channel inactivation. Prog. Biophys. Mol. Biol. 92:185-208. (Pubitemid 43913276)
    • (2006) Progress in Biophysics and Molecular Biology , vol.92 , Issue.2 , pp. 185-208
    • Kurata, H.T.1    Fedida, D.2
  • 28
    • 0042697277 scopus 로고    scopus 로고
    • Atomic proximity between S4 segment and pore domain in shaker potassium channels
    • DOI 10.1016/S0896-6273(03)00468-9
    • Laine, M., M.C. Lin, J.P. Bannister, W.R. Silverman, A.F. Mock, B. Roux, and D.M. Papazian. 2003. Atomic proximity between S4 segment and pore domain in Shaker potassium channels. Neuron. 39:467-481. (Pubitemid 36937048)
    • (2003) Neuron , vol.39 , Issue.3 , pp. 467-481
    • Laine, M.1    Lin, M.-C.A.2    Bannister, J.P.A.3    Silverman, W.R.4    Mock, A.F.5    Roux, B.6    Papazian, D.M.7
  • 29
    • 0033681165 scopus 로고    scopus 로고
    • A conserved glutamate is important for slow inactivation in K+ channels
    • Larsson, H.P., and F. Elinder. 2000. A conserved glutamate is important for slow inactivation in K+ channels. Neuron. 27:573-583.
    • (2000) Neuron , vol.27 , pp. 573-583
    • Larsson, H.P.1    Elinder, F.2
  • 30
    • 0032894433 scopus 로고    scopus 로고
    • Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation
    • DOI 10.1085/jgp.113.3.389
    • Ledwell, J.L., and R.W. Aldrich. 1999. Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J. Gen. Physiol. 113:389-414. (Pubitemid 29219810)
    • (1999) Journal of General Physiology , vol.113 , Issue.3 , pp. 389-414
    • Ledwell, J.L.1    Aldrich, R.W.2
  • 32
    • 0026485457 scopus 로고
    • Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs
    • Liman, E.R., J. Tytgat, and P. Hess. 1992. Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs. Neuron. 9:861-871.
    • (1992) Neuron , vol.9 , pp. 861-871
    • Liman, E.R.1    Tytgat, J.2    Hess, P.3
  • 33
    • 36248982122 scopus 로고    scopus 로고
    • + channel in a lipid membrane-like environment
    • DOI 10.1038/nature06265, PII NATURE06265
    • Long, S.B., X. Tao, E.B. Campbell, and R. MacKinnon. 2007. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature. 450:376-382. (Pubitemid 350126743)
    • (2007) Nature , vol.450 , Issue.7168 , pp. 376-382
    • Long, S.B.1    Tao, X.2    Campbell, E.B.3    MacKinnon, R.4
  • 34
    • 0031718344 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1085/jgp.112.4.377
    • Loots, E., and E.Y. Isacoff. 1998. Protein rearrangements underlying slow inactivation of the Shaker K+ channel. J. Gen. Physiol. 112:377-389. (Pubitemid 28467596)
    • (1998) Journal of General Physiology , vol.112 , Issue.4 , pp. 377-389
    • Loots, E.1    Isacoff, E.Y.2
  • 35
    • 0027828292 scopus 로고
    • Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels
    • Lopez-Barneo, J., T. Hoshi, S.H. Heinemann, and R.W. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
    • (1993) Receptors Channels , vol.1 , pp. 61-71
    • Lopez-Barneo, J.1    Hoshi, T.2    Heinemann, S.H.3    Aldrich, R.W.4
  • 37
    • 0036138908 scopus 로고    scopus 로고
    • A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications
    • DOI 10.1038/nbt0102-87
    • Nagai, T., K. Ibata, E.S. Park, M. Kubota, K. Mikoshiba, and A. Miyawaki. 2002. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat. Biotechnol. 20:87-90. (Pubitemid 34044921)
    • (2002) Nature Biotechnology , vol.20 , Issue.1 , pp. 87-90
    • Nagai, T.1    Ibata, K.2    Park, E.S.3    Kubota, M.4    Mikoshiba, K.5    Miyawaki, A.6
  • 41
    • 0029145067 scopus 로고
    • C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism
    • Panyi, G., Z. Sheng, and C. Deutsch. 1995. C-type inactivation of a voltage-gated K+ channel occurs by a cooperative mechanism. Biophys. J. 69:896-903.
    • (1995) Biophys. J. , vol.69 , pp. 896-903
    • Panyi, G.1    Sheng, Z.2    Deutsch, C.3
  • 42
    • 0023225798 scopus 로고
    • Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila
    • Papazian, D.M., T.L. Schwarz, B.L. Tempel, Y.N. Jan, and L.Y. Jan. 1987. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science. 237:749-753. (Pubitemid 17128266)
    • (1987) Science , vol.237 , Issue.4816 , pp. 749-753
    • Papazian, D.M.1    Schwarz, T.L.2    Tempel, B.L.3
  • 43
    • 0026032209 scopus 로고
    • Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence
    • Papazian, D.M., L.C. Timpe, Y.N. Jan, and L.Y. Jan. 1991. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature. 349:305-310. (Pubitemid 21912066)
    • (1991) Nature , vol.349 , Issue.6307 , pp. 305-310
    • Papazian, D.M.1    Timpe, L.C.2    Jan, Y.N.3    Jan, L.Y.4
  • 44
  • 45
    • 0029097866 scopus 로고
    • Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels
    • Pascual, J.M., C.C. Shieh, G.E. Kirsch, and A.M. Brown. 1995. Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels. Biophys. J. 69:428-434.
    • (1995) Biophys. J. , vol.69 , pp. 428-434
    • Pascual, J.M.1    Shieh, C.C.2    Kirsch, G.E.3    Brown, A.M.4
  • 46
    • 12344259926 scopus 로고    scopus 로고
    • The cooperative voltage sensor motion that gates a potassium channel
    • DOI 10.1085/jgp.200409197
    • Pathak, M., L. Kurtz, F. Tombola, and E. Isacoff. 2005. The cooperative voltage sensor motion that gates a potassium channel. J. Gen. Physiol. 125:57-69. (Pubitemid 40130098)
    • (2005) Journal of General Physiology , vol.125 , Issue.1 , pp. 57-69
    • Pathak, M.1    Kurtz, L.2    Tombola, F.3    Isacoff, E.4
  • 48
    • 0031870974 scopus 로고    scopus 로고
    • + channels. the effect of temperature on ionic and gating currents
    • DOI 10.1085/jgp.112.2.223
    • Rodriguez, B.M., D. Sigg, and F. Bezanilla. 1998. Voltage gating of Shaker K+ channels. The effect of temperature on ionic and gating currents. J. Gen. Physiol. 112:223-242. (Pubitemid 28369162)
    • (1998) Journal of General Physiology , vol.112 , Issue.2 , pp. 223-242
    • Rodriguez, B.M.1    Sigg, D.2    Bezanilla, F.3
  • 49
    • 0031891428 scopus 로고    scopus 로고
    • Activation of Shaker potassium channels: I. Characterization of voltage- Dependent transitions
    • DOI 10.1085/jgp.111.2.271
    • Schoppa, N.E., and F.J. Sigworth. 1998a. Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions. J. Gen. Physiol. 111:271-294. (Pubitemid 28113078)
    • (1998) Journal of General Physiology , vol.111 , Issue.2 , pp. 271-294
    • Schoppa, N.E.1    Sigworth, F.J.2
  • 50
    • 0031952461 scopus 로고    scopus 로고
    • Activation of Shaker potassium channels: III. An activation gating model for wild-type and V2 mutant channels
    • DOI 10.1085/jgp.111.2.313
    • Schoppa, N.E., and F.J. Sigworth. 1998b. Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J. Gen. Physiol. 111:313-342. (Pubitemid 28113080)
    • (1998) Journal of General Physiology , vol.111 , Issue.2 , pp. 313-342
    • Schoppa, N.E.1    Sigworth, F.J.2
  • 51
    • 0030175867 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1016/S0896-6273(00)80142-7
    • Seoh, S.A., D. Sigg, D.M. Papazian, and F. Bezanilla. 1996. Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron. 16:1159-1167. (Pubitemid 26227237)
    • (1996) Neuron , vol.16 , Issue.6 , pp. 1159-1167
    • Seoh, S.-A.1    Sigg, D.2    Papazian, D.M.3    Bezanilla, F.4
  • 52
    • 0027275439 scopus 로고
    • + channels
    • DOI 10.1016/0896-6273(93)90189-X
    • Shao, X.M., and D.M. Papazian. 1993. S4 mutations alter the single-channel gating kinetics of Shaker K+ channels. Neuron. 11:343-352. (Pubitemid 23250351)
    • (1993) Neuron , vol.11 , Issue.2 , pp. 343-352
    • Shao, X.M.1    Papazian, D.M.2
  • 53
    • 0031015351 scopus 로고    scopus 로고
    • Total charge movement per channel: The relation between gating charge displacement and the voltage sensitivity of activation
    • DOI 10.1085/jgp.109.1.27
    • Sigg, D., and F. Bezanilla. 1997. Total charge movement per channel. The relation between gating charge displacement and the voltage sensitivity of activation. J. Gen. Physiol. 109:27-39. (Pubitemid 27030191)
    • (1997) Journal of General Physiology , vol.109 , Issue.1 , pp. 27-39
    • Sigg, D.1    Bezanilla, F.2
  • 54
    • 0019229699 scopus 로고
    • The variance of sodium current fluctuations at the node ofRanvier
    • Sigworth, F.J. 1980. The variance of sodium current fluctuations at the node of Ranvier. J. Physiol. 307:97-129. (Pubitemid 11253739)
    • (1980) Journal of Physiology , vol.VOL.307 , pp. 97-129
    • Sigworth, F.J.1
  • 55
    • 0023212707 scopus 로고
    • Single-channel and genetic analyses reveal two distinct A-type potassium channels in Drosophila
    • Solc, C.K., W.N. Zagotta, and R.W. Aldrich. 1987. Single-channel and genetic analyses reveal two distinct A-type potassium channels in Drosophila. Science. 236:1094-1098. (Pubitemid 17113252)
    • (1987) Science , vol.236 , Issue.4805 , pp. 1094-1098
    • Solc, C.K.1    Zagotta, W.N.2    Aldrich, R.W.3
  • 56
    • 0035039731 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1085/jgp.117.5.469
    • Starace, D.M., and F. Bezanilla. 2001. Histidine scanning mutagenesis of basic residues of the S4 segment of the Shaker K+ channel. J. Gen. Physiol. 117:469-490. (Pubitemid 32441397)
    • (2001) Journal of General Physiology , vol.117 , Issue.5 , pp. 469-490
    • Starace, D.M.1    Bezanilla, F.2
  • 57
    • 1142274549 scopus 로고    scopus 로고
    • A proton pore in a potassium channel voltage sensor reveals a focused electric field
    • DOI 10.1038/nature02270
    • Starace, D.M., and F. Bezanilla. 2004. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 427:548-553. (Pubitemid 38209113)
    • (2004) Nature , vol.427 , Issue.6974 , pp. 548-553
    • Starace, D.M.1    Bezanilla, F.2
  • 58
    • 0031474978 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1016/S0896-6273(00)80422-5
    • Starace, D.M., E. Stefani, and F. Bezanilla. 1997. Voltage-dependent proton transport by the voltage sensor of the Shaker K+ channel. Neuron. 19:1319-1327. (Pubitemid 28030550)
    • (1997) Neuron , vol.19 , Issue.6 , pp. 1319-1327
    • Starace, D.M.1    Stefani, E.2    Bezanilla, F.3
  • 59
    • 0028204485 scopus 로고
    • + channels: I. Ionic and gating currents
    • Stefani, E., L. Toro, E. Perozo, and F. Bezanilla. 1994. Gating of Shaker K+ channels: I. Ionic and gating currents. Biophys. J. 66:996-1010. (Pubitemid 24106346)
    • (1994) Biophysical Journal , vol.66 , Issue.4 , pp. 996-1010
    • Stefani, E.1    Toro, L.2    Perozo, E.3    Bezanilla, F.4
  • 61
    • 33746725967 scopus 로고    scopus 로고
    • Molecular restraints in the permeation pathway of ion channels
    • DOI 10.1529/biophysj.106.087437
    • Treptow, W., and M. Tarek. 2006. Molecular restraints in the permeation pathway of ion channels. Biophys. J. 91:L26-L28. (Pubitemid 44161909)
    • (2006) Biophysical Journal , vol.91 , Issue.3
    • Treptow, W.1    Tarek, M.2
  • 62
    • 0026663246 scopus 로고
    • Evidence for cooperative interactions in potassium channel gating
    • Tytgat, J., and P. Hess. 1992. Evidence for cooperative interactions in potassium channel gating. Nature. 359:420-423.
    • (1992) Nature , vol.359 , pp. 420-423
    • Tytgat, J.1    Hess, P.2
  • 63
    • 39149109885 scopus 로고    scopus 로고
    • Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels
    • Xu, Y., Y. Ramu, and Z. Lu. 2008. Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels. Nature. 451:826-829.
    • (2008) Nature , vol.451 , pp. 826-829
    • Xu, Y.1    Ramu, Y.2    Lu, Z.3
  • 64
    • 0030906796 scopus 로고    scopus 로고
    • How does the W434F mutation block current in Shaker potassium channels?
    • DOI 10.1085/jgp.109.6.779
    • Yang, Y., Y. Yan, and F.J. Sigworth. 1997. How does the W434F mutation block current in Shaker potassium channels? J. Gen. Physiol. 109:779-789. (Pubitemid 27255942)
    • (1997) Journal of General Physiology , vol.109 , Issue.6 , pp. 779-789
    • Yang, Y.1    Yan, Y.2    Sigworth, F.J.3
  • 65
    • 34547113754 scopus 로고    scopus 로고
    • A hydrophobic element secures S4 voltage sensor in position in resting Shaker K+ channels
    • Yang, Y.C., C.J. Own, and C.C. Kuo. 2007. A hydrophobic element secures S4 voltage sensor in position in resting Shaker K+ channels. J. Physiol. 582:1059-1072.
    • (2007) J. Physiol. , vol.582 , pp. 1059-1072
    • Yang, Y.C.1    Own, C.J.2    Kuo, C.C.3
  • 66
    • 0028140472 scopus 로고
    • Shaker potassium channel gating III: Evaluation of kinetic models for activation
    • Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1994a. Shaker potassium channel gating. III: evaluation of kinetic models for activation. J. Gen. Physiol. 103:321-362. (Pubitemid 24068562)
    • (1994) Journal of General Physiology , vol.103 , Issue.2 , pp. 321-362
    • Zagotta, W.N.1    Hoshi, T.2    Aldrich, R.W.3
  • 67
    • 0028085276 scopus 로고
    • Shaker potassium channel gating II: Transitions in the activation pathway
    • Zagotta, W.N., T. Hoshi, J. Dittman, and R.W. Aldrich. 1994b. Shaker potassium channel gating. II: transitions in the activation pathway. J. Gen. Physiol. 103:279-319. (Pubitemid 24068561)
    • (1994) Journal of General Physiology , vol.103 , Issue.2 , pp. 279-319
    • Zagotta, W.N.1    Hoshi, T.2    Dittman, J.3    Aldrich, R.W.4
  • 68
    • 0030818830 scopus 로고    scopus 로고
    • Selectivity changes during activation of mutant Shaker potassium channels
    • DOI 10.1085/jgp.110.2.101
    • Zheng, J., and F.J. Sigworth. 1997. Selectivity changes during activation of mutant Shaker potassium channels. J. Gen. Physiol. 110:101-117. (Pubitemid 27340483)
    • (1997) Journal of General Physiology , vol.110 , Issue.2 , pp. 101-117
    • Zheng, J.1    Sigworth, F.J.2
  • 69
    • 0031718345 scopus 로고    scopus 로고
    • Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels
    • DOI 10.1085/jgp.112.4.457
    • Zheng, J., and F.J. Sigworth. 1998. Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. J. Gen. Physiol. 112:457-474. (Pubitemid 28467602)
    • (1998) Journal of General Physiology , vol.112 , Issue.4 , pp. 457-474
    • Zheng, J.1    Sigworth, F.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.