Cleavable PEGylation and hydrophobic histidylation of polylysine for siRNA delivery and tumor gene therapy

ACS Applied Materials and Interfaces

Volumn 6, Issue 13, 2014, Pages 10393-10407

  Zhu, Haiyan ^a,b   Dong, Chunyan ^b   Dong, Haiqing ^b   Ren, Tianbin ^b,c   Wen, Xuejun ^c   Su, Jiansheng ^a   Li, Yongyong ^b  

^a TONGJI UNIVERSITY   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

disulfide bond; gene therapy; histidine(Bzl); MSCs; RNA interference

Indexed keywords

AMINO ACIDS; CELL CULTURE; COVALENT BONDS; ELECTROPHORESIS; ENDOTHELIAL CELLS; FLOWCHARTING; GENE THERAPY; HYDROPHOBICITY; MOTION PICTURE EXPERTS GROUP STANDARDS; RNA;

AGAROSE GEL ELECTROPHORESIS; DISULFIDE BONDS; HISTIDINE(BZL); INTRACELLULAR REDUCTION; MSCS; RNA INTERFERENCE; SMALL INTERFERING RNA (SIRNA); VASCULAR ENDOTHELIAL GROWTH FACTOR;

TUMORS;

HISTIDINE; MACROGOL DERIVATIVE; POLYLYSINE; SMALL INTERFERING RNA;

AGAR GEL ELECTROPHORESIS; ANIMAL; CHEMICAL PHENOMENA; CHEMISTRY; GENE THERAPY; HEPG2 CELL LINE; HUMAN; MOUSE; NEOPLASMS;

ANIMALS; ELECTROPHORESIS, AGAR GEL; GENETIC THERAPY; HEP G2 CELLS; HISTIDINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICE; NEOPLASMS; POLYETHYLENE GLYCOLS; POLYLYSINE; RNA, SMALL INTERFERING;

EID: 84904122142     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am501928p     Document Type: Article

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