Inhibition of RNAse A family enzymes prevents degradation and loss of silencing activity of siRNAs in serum

Biochemical Pharmacology

Volumn 71, Issue 5, 2006, Pages 702-710

  Haupenthal, Jörg ^a   Baehr, Christina ^a   Kiermayer, Simone ^a   Zeuzem, Stefan ^a   Piiper, Albrecht ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Double stranded RNA; RNAi; RNAse A; Serum; siRNA

Indexed keywords

RECOMBINANT ENZYME; RIBONUCLEASE A; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA DEGRADATION; RNA SEQUENCE; THERMOSTABILITY;

BASE SEQUENCE; CELL LINE; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE SILENCING; HUMANS; HYDROLYSIS; REPRODUCIBILITY OF RESULTS; RIBONUCLEASE, PANCREATIC; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 31044444460     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.11.015     Document Type: Article

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