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Volumn 20, Issue 25, 2014, Pages 8048-8054

Fibrogenesis in alcoholic liver disease

Author keywords

Cytokine; Fibrosis; Kupffer cell; Oxidative stress; Steatohepatitis; Stellate cell

Indexed keywords

4 HYDROXYNONENAL; ACETALDEHYDE; ALPHA SMOOTH MUSCLE ACTIN; ENDOCANNABINOID; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; METHIONINE; OSTEOPONTIN; REACTIVE OXYGEN METABOLITE; S ADENOSYLMETHIONINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; MATRIX METALLOPROTEINASE; MUCIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; AUTACOID;

EID: 84903948693     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i25.8048     Document Type: Article
Times cited : (35)

References (61)
  • 1
    • 84867971003 scopus 로고    scopus 로고
    • Prevalence and natural history of alcoholic liver disease
    • [PMID: 23101975 DOI: 10.1016/j.cld.2012.08.001]
    • Schwartz JM, Reinus JF. Prevalence and natural history of alcoholic liver disease. Clin Liver Dis 2012; 16: 659-666 [PMID: 23101975 DOI: 10.1016/j.cld.2012.08.001]
    • (2012) Clin Liver Dis , vol.16 , pp. 659-666
    • Schwartz, J.M.1    Reinus, J.F.2
  • 2
    • 77949272200 scopus 로고    scopus 로고
    • Etiology of liver cirrhosis in Japan: A nationwide survey
    • [PMID: 19789837 DOI: 10.1007/s00535-009-0128-5]
    • Michitaka K, Nishiguchi S, Aoyagi Y, Hiasa Y, Tokumoto Y, Onji M. Etiology of liver cirrhosis in Japan: a nationwide survey. J Gastroenterol 2010; 45: 86-94 [PMID: 19789837 DOI: 10.1007/s00535-009-0128-5]
    • (2010) J Gastroenterol , vol.45 , pp. 86-94
    • Michitaka, K.1    Nishiguchi, S.2    Aoyagi, Y.3    Hiasa, Y.4    Tokumoto, Y.5    Onji, M.6
  • 3
    • 0027305830 scopus 로고
    • The social cost of alcohol abuse in Japan
    • [PMID: 8412152]
    • Nakamura K, Tanaka A, Takano T. The social cost of alcohol abuse in Japan. J Stud Alcohol 1993; 54: 618-625 [PMID: 8412152]
    • (1993) J Stud Alcohol , vol.54 , pp. 618-625
    • Nakamura, K.1    Tanaka, A.2    Takano, T.3
  • 4
    • 80052433519 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis and new targets for therapy
    • [PMID: 21826088 DOI: 10.1038/nrgastro. 2011.134]
    • Altamirano J, Bataller R. Alcoholic liver disease: pathogenesis and new targets for therapy. Nat Rev Gastroenterol Hepatol 2011; 8: 491-501 [PMID: 21826088 DOI: 10.1038/nrgastro. 2011.134]
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 491-501
    • Altamirano, J.1    Bataller, R.2
  • 5
    • 84867927510 scopus 로고    scopus 로고
    • Histologic findings in alcoholic liver disease
    • [PMID: 23101978 DOI: 10.1016/j.cld.2012.08.004]
    • Crawford JM. Histologic findings in alcoholic liver disease. Clin Liver Dis 2012; 16: 699-716 [PMID: 23101978 DOI: 10.1016/j.cld.2012.08.004]
    • (2012) Clin Liver Dis , vol.16 , pp. 699-716
    • Crawford, J.M.1
  • 6
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
    • [PMID: 18195085 DOI: 10.1152/physrev.00013.2007]
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 2008; 88: 125-172 [PMID: 18195085 DOI: 10.1152/physrev.00013.2007]
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 7
    • 79951803916 scopus 로고    scopus 로고
    • Evolution of hepatic fibrosis research
    • [PMID: 21338451 DOI: 10.1111/j.1872-034X.2011.00776.x]
    • Kawada N. Evolution of hepatic fibrosis research. Hepatol Res 2011; 41: 199-208 [PMID: 21338451 DOI: 10.1111/j.1872-034X.2011.00776.x]
    • (2011) Hepatol Res , vol.41 , pp. 199-208
    • Kawada, N.1
  • 8
    • 84879795972 scopus 로고    scopus 로고
    • Ethanol metabolism and its effects on the intestinal epithelial barrier
    • [PMID: 23815146 DOI: 10.1111/ nure.12027]
    • Elamin EE, Masclee AA, Dekker J, Jonkers DM. Ethanol metabolism and its effects on the intestinal epithelial barrier. Nutr Rev 2013; 71: 483-499 [PMID: 23815146 DOI: 10.1111/ nure.12027]
    • (2013) Nutr Rev , vol.71 , pp. 483-499
    • Elamin, E.E.1    Masclee, A.A.2    Dekker, J.3    Jonkers, D.M.4
  • 9
    • 39849096127 scopus 로고    scopus 로고
    • Alcohol induced hepatic fibrosis: Role of acetaldehyde
    • [PMID: 18164754 DOI: 10.1016/j.mam.2007.10.001]
    • Mello T, Ceni E, Surrenti C, Galli A. Alcohol induced hepatic fibrosis: role of acetaldehyde. Mol Aspects Med 2008; 29: 17-21 [PMID: 18164754 DOI: 10.1016/j.mam.2007.10.001]
    • (2008) Mol Aspects Med , vol.29 , pp. 17-21
    • Mello, T.1    Ceni, E.2    Surrenti, C.3    Galli, A.4
  • 10
    • 79955484604 scopus 로고    scopus 로고
    • Leptin and acetaldehyde synergistically promotes αSMA expression in hepatic stellate cells by an interleukin 6-dependent mechanism
    • [PMID: 21294755 DOI: 10.1111/ j.1530-0277.2010.01422.x]
    • Liu Y, Brymora J, Zhang H, Smith B, Ramezani-Moghadam M, George J, Wang J. Leptin and acetaldehyde synergistically promotes αSMA expression in hepatic stellate cells by an interleukin 6-dependent mechanism. Alcohol Clin Exp Res 2011; 35: 921-928 [PMID: 21294755 DOI: 10.1111/ j.1530-0277.2010.01422.x]
    • (2011) Alcohol Clin Exp Res , vol.35 , pp. 921-928
    • Liu, Y.1    Brymora, J.2    Zhang, H.3    Smith, B.4    Ramezani-Moghadam, M.5    George, J.6    Wang, J.7
  • 11
    • 84872406355 scopus 로고    scopus 로고
    • CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
    • [PMID: 22940046 DOI: 10.1016/j.jhep.2012.08.018]
    • Leung TM, Nieto N. CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. J Hepatol 2013; 58: 395-398 [PMID: 22940046 DOI: 10.1016/j.jhep.2012.08.018]
    • (2013) J Hepatol , vol.58 , pp. 395-398
    • Leung, T.M.1    Nieto, N.2
  • 12
    • 84863143861 scopus 로고    scopus 로고
    • Oxidative stress and redox signaling mechanisms of alcoholic liver disease: Updated experimental and clinical evidence
    • [PMID: 22356308 DOI: 10.1111/j.1751-2980.2011.00569.x]
    • Zhu H, Jia Z, Misra H, Li YR. Oxidative stress and redox signaling mechanisms of alcoholic liver disease: updated experimental and clinical evidence. J Dig Dis 2012; 13: 133-142 [PMID: 22356308 DOI: 10.1111/j.1751-2980.2011.00569.x]
    • (2012) J Dig Dis , vol.13 , pp. 133-142
    • Zhu, H.1    Jia, Z.2    Misra, H.3    Li, Y.R.4
  • 13
    • 33644527617 scopus 로고    scopus 로고
    • Alcohol and oxidative liver injury
    • [PMID: 16447273 DOI: 10.1002/ hep.20957]
    • Dey A, Cederbaum AI. Alcohol and oxidative liver injury. Hepatology 2006; 43: S63-S74 [PMID: 16447273 DOI: 10.1002/ hep.20957]
    • (2006) Hepatology , vol.43
    • Dey, A.1    Cederbaum, A.I.2
  • 14
    • 39749090649 scopus 로고    scopus 로고
    • Oxidative mechanisms in the pathogenesis of alcoholic liver disease
    • [PMID: 18045675 DOI: 10.1016/j.mam.2007.09.004]
    • Albano E. Oxidative mechanisms in the pathogenesis of alcoholic liver disease. Mol Aspects Med 2008; 29: 9-16 [PMID: 18045675 DOI: 10.1016/j.mam.2007.09.004]
    • (2008) Mol Aspects Med , vol.29 , pp. 9-16
    • Albano, E.1
  • 15
    • 79958813517 scopus 로고    scopus 로고
    • Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances
    • [PMID: 21545524 DOI: 10.1111/j.1440-1746.2011.06756.x]
    • Seth D, Haber PS, Syn WK, Diehl AM, Day CP. Pathogenesis of alcohol-induced liver disease: classical concepts and recent advances. J Gastroenterol Hepatol 2011; 26: 1089-1105 [PMID: 21545524 DOI: 10.1111/j.1440-1746.2011.06756.x]
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 1089-1105
    • Seth, D.1    Haber, P.S.2    Syn, W.K.3    Diehl, A.M.4    Day, C.P.5
  • 16
    • 79958058366 scopus 로고    scopus 로고
    • Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease
    • [PMID: 21354120 DOI: 10.1016/j.cbi.2011.02.021]
    • Smathers RL, Galligan JJ, Stewart BJ, Petersen DR. Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease. Chem Biol Interact 2011; 192: 107-112 [PMID: 21354120 DOI: 10.1016/j.cbi.2011.02.021]
    • (2011) Chem Biol Interact , vol.192 , pp. 107-112
    • Smathers, R.L.1    Galligan, J.J.2    Stewart, B.J.3    Petersen, D.R.4
  • 17
    • 34250315771 scopus 로고    scopus 로고
    • Ethanol and fish oil induce NFkappaB transactivation of the collagen alpha2(I) promoter through lipid peroxidation-driven activation of the PKC-PI3K-Akt pathway
    • [PMID: 17538965 DOI: 10.1002/hep.21659]
    • Nieto N. Ethanol and fish oil induce NFkappaB transactivation of the collagen alpha2(I) promoter through lipid peroxidation-driven activation of the PKC-PI3K-Akt pathway. Hepatology 2007; 45: 1433-1445 [PMID: 17538965 DOI: 10.1002/hep.21659]
    • (2007) Hepatology , vol.45 , pp. 1433-1445
    • Nieto, N.1
  • 18
    • 84871863138 scopus 로고    scopus 로고
    • Methionine metabolic pathway in alcoholic liver injury
    • [PMID: 23232418 DOI: 10.1097/MCO.0b013e32835a892a]
    • Kharbanda KK. Methionine metabolic pathway in alcoholic liver injury. Curr Opin Clin Nutr Metab Care 2013; 16: 89-95 [PMID: 23232418 DOI: 10.1097/MCO.0b013e32835a892a]
    • (2013) Curr Opin Clin Nutr Metab Care , vol.16 , pp. 89-95
    • Kharbanda, K.K.1
  • 19
    • 80054872790 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis and new therapeutic targets
    • [PMID: 21920463 DOI: 10.1053/j.gastro.2011.09.002]
    • Gao B, Bataller R. Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 2011; 141: 1572-1585 [PMID: 21920463 DOI: 10.1053/j.gastro.2011.09.002]
    • (2011) Gastroenterology , vol.141 , pp. 1572-1585
    • Gao, B.1    Bataller, R.2
  • 20
    • 79954514102 scopus 로고    scopus 로고
    • Apoptosis in nonalcoholic fatty liver disease: Diagnostic and therapeutic implications
    • [PMID: 21476915 DOI: 10.1586/egh.11.6]
    • Alkhouri N, Carter-Kent C, Feldstein AE. Apoptosis in nonalcoholic fatty liver disease: diagnostic and therapeutic implications. Expert Rev Gastroenterol Hepatol 2011; 5: 201-212 [PMID: 21476915 DOI: 10.1586/egh.11.6]
    • (2011) Expert Rev Gastroenterol Hepatol , vol.5 , pp. 201-212
    • Alkhouri, N.1    Carter-Kent, C.2    Feldstein, A.E.3
  • 21
    • 84885332714 scopus 로고    scopus 로고
    • STINGIRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
    • [PMID: 24052526 DOI: 10.1073/pnas.1308331110]
    • Petrasek J, Iracheta-Vellve A, Csak T, Satishchandran A, Kodys K, Kurt-Jones EA, Fitzgerald KA, Szabo G. STINGIRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. Proc Natl Acad Sci USA 2013; 110: 16544-16549 [PMID: 24052526 DOI: 10.1073/pnas.1308331110]
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 16544-16549
    • Petrasek, J.1    Iracheta-Vellve, A.2    Csak, T.3    Satishchandran, A.4    Kodys, K.5    Kurt-Jones, E.A.6    Fitzgerald, K.A.7    Szabo, G.8
  • 22
    • 79957834830 scopus 로고    scopus 로고
    • Hepatic stellate cells and innate immunity in alcoholic liver disease
    • [PMID: 21633659 DOI: 10.3748/wjg.v17.i20.2543]
    • Suh YG, Jeong WI. Hepatic stellate cells and innate immunity in alcoholic liver disease. World J Gastroenterol 2011; 17: 2543-2551 [PMID: 21633659 DOI: 10.3748/wjg.v17.i20.2543]
    • (2011) World J Gastroenterol , vol.17 , pp. 2543-2551
    • Suh, Y.G.1    Jeong, W.I.2
  • 23
    • 79952796670 scopus 로고    scopus 로고
    • Serum markers of hepatocyte death and apoptosis are non invasive biomarkers of severe fibrosis in patients with alcoholic liver disease
    • [PMID: 21445263 DOI: 10.1371/journal.pone.0017599]
    • Lavallard VJ, Bonnafous S, Patouraux S, Saint-Paul MC, Rousseau D, Anty R, Le Marchand-Brustel Y, Tran A, Gual P. Serum markers of hepatocyte death and apoptosis are non invasive biomarkers of severe fibrosis in patients with alcoholic liver disease. PLoS One 2011; 6: e17599 [PMID: 21445263 DOI: 10.1371/journal.pone.0017599]
    • (2011) PLoS One , vol.6
    • Lavallard, V.J.1    Bonnafous, S.2    Patouraux, S.3    Saint-Paul, M.C.4    Rousseau, D.5    Anty, R.6    Le Marchand-Brustel, Y.7    Tran, A.8    Gual, P.9
  • 24
    • 84870986481 scopus 로고    scopus 로고
    • Toll-like receptors in liver disease
    • [PMID: 23461136]
    • Petrasek J, Csak T, Szabo G. Toll-like receptors in liver disease. Adv Clin Chem 2013; 59: 155-201 [PMID: 23461136]
    • (2013) Adv Clin Chem , vol.59 , pp. 155-201
    • Petrasek, J.1    Csak, T.2    Szabo, G.3
  • 26
    • 79251482742 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells
    • [PMID: 21274885 DOI: 10.1002/hep.24059]
    • Petrasek J, Dolganiuc A, Csak T, Nath B, Hritz I, Kodys K, Catalano D, Kurt-Jones E, Mandrekar P, Szabo G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology 2011; 53: 649-660 [PMID: 21274885 DOI: 10.1002/hep.24059]
    • (2011) Hepatology , vol.53 , pp. 649-660
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Nath, B.4    Hritz, I.5    Kodys, K.6    Catalano, D.7    Kurt-Jones, E.8    Mandrekar, P.9    Szabo, G.10
  • 27
    • 77955686233 scopus 로고    scopus 로고
    • Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver
    • [PMID: 20564354 DOI: 10.1002/hep.23739]
    • Jagavelu K, Routray C, Shergill U, O'Hara SP, Faubion W, Shah VH. Endothelial cell toll-like receptor 4 regulates fibrosis-associated angiogenesis in the liver. Hepatology 2010; 52: 590-601 [PMID: 20564354 DOI: 10.1002/hep.23739]
    • (2010) Hepatology , vol.52 , pp. 590-601
    • Jagavelu, K.1    Routray, C.2    Shergill, U.3    O'Hara, S.P.4    Faubion, W.5    Shah, V.H.6
  • 29
    • 68949178506 scopus 로고    scopus 로고
    • Endotoxemia and gut barrier dysfunction in alcoholic liver disease
    • [PMID: 19575462 DOI: 10.1002/hep.23009]
    • Rao R. Endotoxemia and gut barrier dysfunction in alcoholic liver disease. Hepatology 2009; 50: 638-644 [PMID: 19575462 DOI: 10.1002/hep.23009]
    • (2009) Hepatology , vol.50 , pp. 638-644
    • Rao, R.1
  • 31
    • 70349312850 scopus 로고    scopus 로고
    • Current experimental perspectives on the clinical progression of alcoholic liver disease
    • [PMID: 19645734 DOI: 10.1111/ j.1530-0277.2009.01015.x]
    • Breitkopf K, Nagy LE, Beier JI, Mueller S, Weng H, Dooley S. Current experimental perspectives on the clinical progression of alcoholic liver disease. Alcohol Clin Exp Res 2009; 33: 1647-1655 [PMID: 19645734 DOI: 10.1111/ j.1530-0277.2009.01015.x]
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1647-1655
    • Breitkopf, K.1    Nagy, L.E.2    Beier, J.I.3    Mueller, S.4    Weng, H.5    Dooley, S.6
  • 34
    • 77952422323 scopus 로고    scopus 로고
    • Adenosine: Tipping the balance towards hepatic steatosis and fibrosis
    • [PMID: 20395005 DOI: 10.1016/j.jhep.2010.02.009]
    • Robson SC, Schuppan D. Adenosine: tipping the balance towards hepatic steatosis and fibrosis. J Hepatol 2010; 52: 941-943 [PMID: 20395005 DOI: 10.1016/j.jhep.2010.02.009]
    • (2010) J Hepatol , vol.52 , pp. 941-943
    • Robson, S.C.1    Schuppan, D.2
  • 35
    • 79955635993 scopus 로고    scopus 로고
    • Role of cannabinoid receptors in alcoholic hepatic injury: Steatosis and fibrogenesis are increased in CB2 receptordeficient mice and decreased in CB1 receptor knockouts
    • [PMID: 21645218 DOI: 10.1111/ j.1478-3231.2011.02496.x]
    • Trebicka J, Racz I, Siegmund SV, Cara E, Granzow M, Schierwagen R, Klein S, Wojtalla A, Hennenberg M, Huss S, Fischer HP, Heller J, Zimmer A, Sauerbruch T. Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptordeficient mice and decreased in CB1 receptor knockouts. Liver Int 2011; 31: 860-870 [PMID: 21645218 DOI: 10.1111/ j.1478-3231.2011.02496.x]
    • (2011) Liver Int , vol.31 , pp. 860-870
    • Trebicka, J.1    Racz, I.2    Siegmund, S.V.3    Cara, E.4    Granzow, M.5    Schierwagen, R.6    Klein, S.7    Wojtalla, A.8    Hennenberg, M.9    Huss, S.10    Fischer, H.P.11    Heller, J.12    Zimmer, A.13    Sauerbruch, T.14
  • 36
    • 84884905298 scopus 로고    scopus 로고
    • Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease
    • [PMID: 23688501 DOI: 10.1016/j.bcp.2013.05.007]
    • Sid B, Verrax J, Calderon PB. Role of AMPK activation in oxidative cell damage: Implications for alcohol-induced liver disease. Biochem Pharmacol 2013; 86: 200-209 [PMID: 23688501 DOI: 10.1016/j.bcp.2013.05.007]
    • (2013) Biochem Pharmacol , vol.86 , pp. 200-209
    • Sid, B.1    Verrax, J.2    Calderon, P.B.3
  • 37
    • 78751551237 scopus 로고    scopus 로고
    • Endocannabinoids in liver disease
    • [PMID: 21254182 DOI: 10.1002/hep.24077]
    • Tam J, Liu J, Mukhopadhyay B, Cinar R, Godlewski G, Kunos G. Endocannabinoids in liver disease. Hepatology 2011; 53: 346-355 [PMID: 21254182 DOI: 10.1002/hep.24077]
    • (2011) Hepatology , vol.53 , pp. 346-355
    • Tam, J.1    Liu, J.2    Mukhopadhyay, B.3    Cinar, R.4    Godlewski, G.5    Kunos, G.6
  • 38
    • 79960297797 scopus 로고    scopus 로고
    • The endocannabinoid system as a key mediator during liver diseases: New insights and therapeutic openings
    • [PMID: 21457226 DOI: 10.1111/j.1476-5381.2011.01397.x]
    • Mallat A, Teixeira-Clerc F, Deveaux V, Manin S, Lotersztajn S. The endocannabinoid system as a key mediator during liver diseases: new insights and therapeutic openings. Br J Pharmacol 2011; 163: 1432-1440 [PMID: 21457226 DOI: 10.1111/j.1476-5381.2011.01397.x]
    • (2011) Br J Pharmacol , vol.163 , pp. 1432-1440
    • Mallat, A.1    Teixeira-Clerc, F.2    Deveaux, V.3    Manin, S.4    Lotersztajn, S.5
  • 40
    • 84891826248 scopus 로고    scopus 로고
    • Osteopontin: Versatile modulator of liver diseases
    • [PMID: 23701387 DOI: 10.1111/hepr.12166]
    • Nagoshi S. Osteopontin: Versatile modulator of liver diseases. Hepatol Res 2014; 44: 22-30 [PMID: 23701387 DOI: 10.1111/hepr.12166]
    • (2014) Hepatol Res , vol.44 , pp. 22-30
    • Nagoshi, S.1
  • 42
    • 84863042103 scopus 로고    scopus 로고
    • Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling
    • [PMID: 21953216 DOI: 10.1002/hep.24701]
    • Urtasun R, Lopategi A, George J, Leung TM, Lu Y, Wang X, Ge X, Fiel MI, Nieto N. Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling. Hepatology 2012; 55: 594-608 [PMID: 21953216 DOI: 10.1002/hep.24701]
    • (2012) Hepatology , vol.55 , pp. 594-608
    • Urtasun, R.1    Lopategi, A.2    George, J.3    Leung, T.M.4    Lu, Y.5    Wang, X.6    Ge, X.7    Fiel, M.I.8    Nieto, N.9
  • 45
    • 78649632996 scopus 로고    scopus 로고
    • Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria
    • [PMID: 20970216 DOI: 10.1016/j.jhep.2010.06.030]
    • Sieghart W, Wang X, Schmid K, Pinter M, König F, Bodingbauer M, Wrba F, Rasoul-Rockenschaub S, Peck-Radosavljevic M. Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria. J Hepatol 2011; 54: 89-97 [PMID: 20970216 DOI: 10.1016/j.jhep.2010.06.030]
    • (2011) J Hepatol , vol.54 , pp. 89-97
    • Sieghart, W.1    Wang, X.2    Schmid, K.3    Pinter, M.4    König, F.5    Bodingbauer, M.6    Wrba, F.7    Rasoul-Rockenschaub, S.8    Peck-Radosavljevic, M.9
  • 47
    • 77953891627 scopus 로고    scopus 로고
    • Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice
    • [PMID: 20347818 DOI: 10.1053/j.gastro.2010.03.052]
    • Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology 2010; 139: 323-324. e7 [PMID: 20347818 DOI: 10.1053/j.gastro.2010.03.052]
    • (2010) Gastroenterology , vol.139
    • Miura, K.1    Kodama, Y.2    Inokuchi, S.3    Schnabl, B.4    Aoyama, T.5    Ohnishi, H.6    Olefsky, J.M.7    Brenner, D.A.8    Seki, E.9
  • 48
    • 67049172488 scopus 로고    scopus 로고
    • Interleukin-1 participates in the progression from liver injury to fibrosis
    • [PMID: 19342509 DOI: 10.1152/ajpgi.90564.2008]
    • Gieling RG, Wallace K, Han YP. Interleukin-1 participates in the progression from liver injury to fibrosis. Am J Physiol Gastrointest Liver Physiol 2009; 296: G1324-G1331 [PMID: 19342509 DOI: 10.1152/ajpgi.90564.2008]
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Gieling, R.G.1    Wallace, K.2    Han, Y.P.3
  • 49
    • 79251600358 scopus 로고    scopus 로고
    • Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice
    • [PMID: 20727895 DOI: 10.1053/j.gastro.2010.08.020]
    • Petrasek J, Dolganiuc A, Csak T, Kurt-Jones EA, Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology 2011; 140: 697-708. e4 [PMID: 20727895 DOI: 10.1053/j.gastro.2010.08.020]
    • (2011) Gastroenterology , vol.140
    • Petrasek, J.1    Dolganiuc, A.2    Csak, T.3    Kurt-Jones, E.A.4    Szabo, G.5
  • 51
    • 84876705957 scopus 로고    scopus 로고
    • Therapeutic potential of interleukin 1 inhibitors in the treatment of alcoholic liver disease
    • [PMID: 23609413 DOI: 10.1002/ hep.26336]
    • Mathews S, Gao B. Therapeutic potential of interleukin 1 inhibitors in the treatment of alcoholic liver disease. Hepatology 2013; 57: 2078-2080 [PMID: 23609413 DOI: 10.1002/ hep.26336]
    • (2013) Hepatology , vol.57 , pp. 2078-2080
    • Mathews, S.1    Gao, B.2
  • 52
    • 83455259910 scopus 로고    scopus 로고
    • Genetic determinants of alcoholic liver disease
    • [PMID: 22110053 DOI: 10.1136/gutjnl-2011-301239]
    • Stickel F, Hampe J. Genetic determinants of alcoholic liver disease. Gut 2012; 61: 150-159 [PMID: 22110053 DOI: 10.1136/gutjnl-2011-301239]
    • (2012) Gut , vol.61 , pp. 150-159
    • Stickel, F.1    Hampe, J.2
  • 53
    • 41149164581 scopus 로고    scopus 로고
    • Evaluation of the transforming growth factor beta1 codon 25 (Arg--& gt; Pro) polymorphism in alcoholic liver disease
    • [PMID: 18337117 DOI: 10.1016/j.cyto.2008.02.003]
    • Osterreicher CH, Halangk J, Berg T, Patsenker E, Homann N, Hellerbrand C, Seitz HK, Eurich D, Stickel F. Evaluation of the transforming growth factor beta1 codon 25 (Arg--& gt; Pro) polymorphism in alcoholic liver disease. Cytokine 2008; 42: 18-23 [PMID: 18337117 DOI: 10.1016/j.cyto.2008.02.003]
    • (2008) Cytokine , vol.42 , pp. 18-23
    • Osterreicher, C.H.1    Halangk, J.2    Berg, T.3    Patsenker, E.4    Homann, N.5    Hellerbrand, C.6    Seitz, H.K.7    Eurich, D.8    Stickel, F.9
  • 55
    • 78649903976 scopus 로고    scopus 로고
    • Genome-wide association studies and genetic risk assessment of liver diseases
    • [PMID: 21045792 DOI: 10.1038/nrgastro.2010.170]
    • Krawczyk M, Müllenbach R, Weber SN, Zimmer V, Lammert F. Genome-wide association studies and genetic risk assessment of liver diseases. Nat Rev Gastroenterol Hepatol 2010; 7: 669-681 [PMID: 21045792 DOI: 10.1038/nrgastro.2010.170]
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 669-681
    • Krawczyk, M.1    Müllenbach, R.2    Weber, S.N.3    Zimmer, V.4    Lammert, F.5
  • 57
    • 73349111259 scopus 로고    scopus 로고
    • Variant in PNPLA3 is associated with alcoholic liver disease
    • [PMID: 19946271 DOI: 10.1038/ng.488]
    • Tian C, Stokowski RP, Kershenobich D, Ballinger DG, Hinds DA. Variant in PNPLA3 is associated with alcoholic liver disease. Nat Genet 2010; 42: 21-23 [PMID: 19946271 DOI: 10.1038/ng.488]
    • (2010) Nat Genet , vol.42 , pp. 21-23
    • Tian, C.1    Stokowski, R.P.2    Kershenobich, D.3    Ballinger, D.G.4    Hinds, D.A.5
  • 58
    • 84859147155 scopus 로고    scopus 로고
    • PNPLA3 (rs738409 C& gt; G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis
    • [PMID: 22162034 DOI: 10.1002/ hep.25518]
    • Trepo E, Guyot E, Ganne-Carrie N, Degre D, Gustot T, Franchimont D, Sutton A, Nahon P, Moreno C. PNPLA3 (rs738409 C& gt; G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis. Hepatology 2012; 55: 1307-1308 [PMID: 22162034 DOI: 10.1002/ hep.25518]
    • (2012) Hepatology , vol.55 , pp. 1307-1308
    • Trepo, E.1    Guyot, E.2    Ganne-Carrie, N.3    Degre, D.4    Gustot, T.5    Franchimont, D.6    Sutton, A.7    Nahon, P.8    Moreno, C.9
  • 60
    • 77950625747 scopus 로고    scopus 로고
    • Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease
    • [PMID: 20373372 DOI: 10.1002/hep.23606]
    • Seth D, Daly AK, Haber PS, Day CP. Patatin-like phospholipase domain containing 3: a case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease. Hepatology 2010; 51: 1463-1465 [PMID: 20373372 DOI: 10.1002/hep.23606]
    • (2010) Hepatology , vol.51 , pp. 1463-1465
    • Seth, D.1    Daly, A.K.2    Haber, P.S.3    Day, C.P.4


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