PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis

Liver International

Volumn 34, Issue 4, 2014, Pages 514-520

  Burza, Maria Antonella ^a   Molinaro, Antonio ^b   Attilia, Maria Luisa ^b   Rotondo, Claudia ^b   Attilia, Fabio ^b   Ceccanti, Mauro ^b   Ferri, Flaminia ^b   Maldarelli, Federica ^b   Maffongelli, Angela ^b   De Santis, Adriano ^b   Attili, Adolfo Francesco ^b   Romeo, Stefano ^a,c   Ginanni Corradini, Stefano ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Age at onset; Alcohol intake; Alcoholic liver disease; Genetics; Incidence; Patatin like phospholipase domain containing protein 3; Polymorphism

Indexed keywords

ALCOHOL; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 3 I148M; PHOSPHOLIPASE; UNCLASSIFIED DRUG;

ADULT; AGE; ALCOHOL CONSUMPTION; ALCOHOL LIVER CIRRHOSIS; ALLELE; ARTICLE; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; ONSET AGE; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR;

AGE AT ONSET; ALCOHOL INTAKE; ALCOHOLIC LIVER DISEASE; GENETICS; INCIDENCE; PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3; POLYMORPHISM;

ADULT; AGE OF ONSET; ALCOHOL DRINKING; GENOTYPE; HUMANS; INCIDENCE; ITALY; KAPLAN-MEIER ESTIMATE; LINEAR MODELS; LIPASE; LIVER CIRRHOSIS, ALCOHOLIC; MEMBRANE PROTEINS; MODELS, GENETIC; MUTATION, MISSENSE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84895819606     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12310     Document Type: Article

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