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Volumn 63, Issue 7, 2014, Pages 643-662

Manipulation of tumour-infiltrating B cells and tertiary lymphoid structures: A novel anti-cancer treatment avenue?

Author keywords

Cancer immunotherapy; Cancer therapy; Tertiary lymphoid structures; Tumour infiltrating B cells

Indexed keywords

AUTOANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G; INTERLEUKIN 10;

EID: 84903818166     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-014-1544-9     Document Type: Review
Times cited : (53)

References (179)
  • 1
    • 84877138564 scopus 로고    scopus 로고
    • Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer
    • doi:10.1007/s00262-012-1390-6
    • Ramakrishnan R, Gabrilovich DI (2013) Novel mechanism of synergistic effects of conventional chemotherapy and immune therapy of cancer. Cancer Immunol Immunother 62(3):405-410. doi:10.1007/s00262-012-1390-6
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.3 , pp. 405-410
    • Ramakrishnan, R.1    Gabrilovich, D.I.2
  • 3
    • 84864041109 scopus 로고    scopus 로고
    • Complete clinical responses to cancer therapy caused by multiple divergent approaches: A repeating theme lost in translation
    • doi:10.2147/CMAR.S31887
    • Coventry BJ, Ashdown ML (2012) Complete clinical responses to cancer therapy caused by multiple divergent approaches: a repeating theme lost in translation. Cancer Manag Res 4:137-149. doi:10.2147/CMAR.S31887
    • (2012) Cancer Manag Res , vol.4 , pp. 137-149
    • Coventry, B.J.1    Ashdown, M.L.2
  • 4
    • 84861108403 scopus 로고    scopus 로고
    • The tipping point for combination therapy: Cancer vaccines with radiation, chemotherapy, or targeted small molecule inhibitors
    • doi:10.1053/j.seminon col.2012.02.006
    • Hodge JW, Ardiani A, Farsaci B, Kwilas AR, Gameiro SR (2012) The tipping point for combination therapy: cancer vaccines with radiation, chemotherapy, or targeted small molecule inhibitors. Semin Oncol 39(3):323-339. doi:10.1053/j.seminon col.2012.02.006
    • (2012) Semin Oncol , vol.39 , Issue.3 , pp. 323-339
    • Hodge, J.W.1    Ardiani, A.2    Farsaci, B.3    Kwilas, A.R.4    Gameiro, S.R.5
  • 5
    • 80052206084 scopus 로고    scopus 로고
    • Prognostic and predictive impact of intra- and peritumoral immune infiltrates
    • doi:10.1158/0008-5472.CAN-11-1316
    • Fridman WH, Galon J, Pages F, Tartour E, Sautes-Fridman C, Kroemer G (2011) Prognostic and predictive impact of intra- and peritumoral immune infiltrates. Cancer Res 71(17):5601-5605. doi:10.1158/0008-5472.CAN-11-1316
    • (2011) Cancer Res , vol.71 , Issue.17 , pp. 5601-5605
    • Fridman, W.H.1    Galon, J.2    Pages, F.3    Tartour, E.4    Sautes-Fridman, C.5    Kroemer, G.6
  • 6
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • doi:10.1038/nrc3245
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J (2012) The immune contexture in human tumours: impact on clinical outcome. NatRev Cancer 12(4):298-306. doi:10.1038/nrc3245
    • (2012) NatRev Cancer , vol.12 , Issue.4 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 8
    • 0017173437 scopus 로고
    • Identification of T and B lymphocytes in human breast cancer with immunohistochemical techniques
    • Schoorl R, Riviere AB, Borne AE, Feltkamp-Vroom TM (1976) Identification of T and B lymphocytes in human breast cancer with immunohistochemical techniques. Am J Pathol 84(3):529-544
    • (1976) Am J Pathol , vol.84 , Issue.3 , pp. 529-544
    • Schoorl, R.1    Riviere, A.B.2    Borne, A.E.3    Feltkamp-Vroom, T.M.4
  • 9
    • 0030069578 scopus 로고    scopus 로고
    • Lymphocyte subset infiltration patterns and HLA antigen status in colorectal carcinomas and adenomas
    • Jackson PA, Green MA, Marks CG, King RJ, Hubbard R, Cook MG (1996) Lymphocyte subset infiltration patterns and HLA antigen status in colorectal carcinomas and adenomas. Gut 38(1):85-89. doi:10.1136/gut.38.1.85 (Pubitemid 26020934)
    • (1996) Gut , vol.38 , Issue.1 , pp. 85-89
    • Jackson, P.A.1    Green, M.A.2    Marks, C.G.3    King, R.J.B.4    Hubbard, R.5    Cook, M.G.6
  • 11
    • 0020060190 scopus 로고
    • Identification of lymphocyte subpopulations in human breast cancer tissue and its significance. An immunoperoxidase study with anti-human T- and B-cell sera
    • DOI 10.1002/1097-0142(19820401)49:7<1456::AID-CNCR
    • Shimokawara I, Imamura M, Yamanaka N, Ishii Y, Kikuchi K (1982) Identification of lymphocyte subpopulations in human breast cancer tissue and its significance: an immunoperoxidase study with anti-human T- and B-cell sera. Cancer 49(7):1456-1464. doi:10.1002/1097-0142(19820401)49:7〈1456::AID- CNCR2820490724〉3.0.CO;2-# (Pubitemid 12143070)
    • (1982) Cancer , vol.49 , Issue.7 , pp. 1456-1464
    • Shimokawara, I.1    Imamura, M.2    Yamanaka, N.3
  • 12
    • 0027254491 scopus 로고
    • + and B lymphocytes in transplantation immunity: II. Augmented rejection of tumor allografts by mice lacking B cells
    • Monach PA, Schreiber H, Rowley DA (1993) CD4+ and B lymphocytes in transplantation immunity. II. Augmented rejection of tumor allografts by mice lacking B cells. Transplantation 55(6):1356-1361 (Pubitemid 23183251)
    • (1993) Transplantation , vol.55 , Issue.6 , pp. 1356-1361
    • Monach, P.A.1    Schreiber, H.2    Rowley, D.A.3
  • 13
    • 0018190839 scopus 로고
    • Anti-tumor immunity in B lymphocyte-deprived mice. I. Immunity to a chemically induced tumor
    • Brodt P, Gordon J (1978) Anti-tumor immunity in B lympho-cyte-deprived mice. I. Immunity to a chemically induced tumor. J Immunol 121(1):359-362 (Pubitemid 8384890)
    • (1978) Journal of Immunology , vol.121 , Issue.1 , pp. 359-362
    • Brodt, P.1    Gordon, J.2
  • 14
    • 84864453237 scopus 로고    scopus 로고
    • B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-alpha, perforin)
    • doi:10.1002/ijc.27411
    • Kammertoens T, Qin Z, Briesemeister D, Bendelac A, Blankenstein T (2012) B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-alpha, perforin). Int J Cancer 131(7):1499-1508. doi:10.1002/ijc.27411
    • (2012) Int J Cancer , vol.131 , Issue.7 , pp. 1499-1508
    • Kammertoens, T.1    Qin, Z.2    Briesemeister, D.3    Bendelac, A.4    Blankenstein, T.5
  • 16
    • 19344365408 scopus 로고    scopus 로고
    • De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent
    • DOI 10.1016/j.ccr.2005.04.014, PII S153561080500125X
    • de Visser KE, Korets LV, Coussens LM (2005) De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7(5):411-423. doi:10.1016/j.ccr.2005.04.014 (Pubitemid 40719125)
    • (2005) Cancer Cell , vol.7 , Issue.5 , pp. 411-423
    • De Visser, K.E.1    Korets, L.V.2    Coussens, L.M.3
  • 17
    • 84886943750 scopus 로고    scopus 로고
    • B cell-regulated immune responses in tumor models and cancer patients
    • doi:10.4161/onci.25443
    • Fremd C, Schuetz F, Sohn C, Beckhove P, Domschke C (2013) B cell-regulated immune responses in tumor models and cancer patients. Oncoimmunology 2(7):e25443. doi:10.4161/onci.25443
    • (2013) Oncoimmunology , vol.2 , Issue.7
    • Fremd, C.1    Schuetz, F.2    Sohn, C.3    Beckhove, P.4    Domschke, C.5
  • 18
    • 0026532143 scopus 로고
    • Functional capacity of a tumor-infiltrating B-cell line: Lymphokine secretion
    • doi:10.1007/BF02918606
    • Wu CW, Wang SY, Chiang H, Lui WY, P'Eng FK, Ho CK (1992) Functional capacity of a tumor-infiltrating B-cell line: lymphokine secretion. Immunol Res 11(1):34-41. doi:10.1007/BF02918606
    • (1992) Immunol Res , vol.11 , Issue.1 , pp. 34-41
    • Wu, C.W.1    Wang, S.Y.2    Chiang, H.3    Lui, W.Y.4    P'Eng, F.K.5    Ho, C.K.6
  • 19
    • 0028672882 scopus 로고
    • Inhibition of tumor cell growth by a human B-cell line
    • doi:10.1007/BF01878115
    • Katano M, Kubota E, Nagumo F, Matsuo T, Hisatsugu T, Tadano J (1994) Inhibition of tumor cell growth by a human B-cell line. Biotherapy 8(1):1-6. doi:10.1007/BF01878115
    • (1994) Biotherapy , vol.8 , Issue.1 , pp. 1-6
    • Katano, M.1    Kubota, E.2    Nagumo, F.3    Matsuo, T.4    Hisatsugu, T.5    Tadano, J.6
  • 20
    • 0028786782 scopus 로고
    • Tumor growth inhibition mediated by lymphotoxin: Evidence of B lymphocyte involvement in the antitumor response
    • Qin Z, Blankenstein T (1995) Tumor growth inhibition mediated by lymphotoxin: evidence of B lymphocyte involvement in the antitumor response. Cancer Res 55(21):4747-4751
    • (1995) Cancer Res , vol.55 , Issue.21 , pp. 4747-4751
    • Qin, Z.1    Blankenstein, T.2
  • 21
    • 0024595601 scopus 로고
    • Nuclear disintegration of target cells by killer B lymphocytes from tumor-bearing mice
    • Lopez DM, Blomberg BB, Padmanabhan RR, Bourguignon LY (1989) Nuclear disintegration of target cells by killer B lymphocytes from tumor-bearing mice. FASEB J 3(1):37-43 (Pubitemid 19042563)
    • (1989) FASEB Journal , vol.3 , Issue.1 , pp. 37-43
    • Lopez, D.M.1    Blomberg, B.B.2    Padmanabhan, R.R.3    Bourguignon, L.Y.W.4
  • 22
    • 0017248181 scopus 로고
    • Functional activity of splenic T- and B-cells during the process of tumor growth
    • Norimov A, Khaitov RM, Gambarov SS (1976) Functional activity of splenic T- and B-cells during the process of tumor growth. Biull Eksp Biol Med 82(12):1475-1477
    • (1976) Biull Eksp Biol Med , vol.82 , Issue.12 , pp. 1475-1477
    • Norimov, A.1    Khaitov, R.M.2    Gambarov, S.S.3
  • 23
    • 0022534820 scopus 로고
    • Lymphocyte subpopulations infiltrating squamous carcinomas of the head and neck: Correlations with extent of tumor and prognosis
    • Wolf GT, Hudson JL, Peterson KA, Miller HL, McClatchey KD (1986) Lymphocyte subpopulations infiltrating squamous carcinomas of the head and neck: correlations with extent of tumor and prognosis. Otolaryngol Head Neck Surg 95(2):142-152 (Pubitemid 16025387)
    • (1986) Otolaryngology - Head and Neck Surgery , vol.95 , Issue.2 , pp. 142-152
    • Wolf, G.T.1    Hudson, J.L.2    Peterson, K.A.3
  • 25
    • 84862025685 scopus 로고    scopus 로고
    • The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer
    • doi:10.1038/bjc.2012.211
    • Richards CH, Flegg KM, Roxburgh CS, Going JJ, Mohammed Z, Horgan PG, McMillan DC (2012) The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer. Br J Cancer 106(12):2010-2015. doi:10.1038/bjc.2012.211
    • (2012) Br J Cancer , vol.106 , Issue.12 , pp. 2010-2015
    • Richards, C.H.1    Flegg, K.M.2    Roxburgh, C.S.3    Going, J.J.4    Mohammed, Z.5    Horgan, P.G.6    McMillan, D.C.7
  • 28
    • 84886944497 scopus 로고    scopus 로고
    • Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
    • doi:10.4161/onci.21653
    • Schmidt M, Micke P, Gehrmann M, Hengstler JG (2012) Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors. Oncoimmunology 1(7):1156-1158. doi:10.4161/onci.21653
    • (2012) Oncoimmunology , vol.1 , Issue.7 , pp. 1156-1158
    • Schmidt, M.1    Micke, P.2    Gehrmann, M.3    Hengstler, J.G.4
  • 30
    • 84859102962 scopus 로고    scopus 로고
    • The prognostic significance of B lymphocytes in invasive carcinoma of the breast
    • doi:10.1007/s10549-011-1620-1
    • Mahmoud SM, Lee AH, Paish EC, Macmillan RD, Ellis IO, Green AR (2012) The prognostic significance of B lymphocytes in invasive carcinoma of the breast. Breast Cancer Res Treat 132(2):545-553. doi:10.1007/s10549-011-1620-1
    • (2012) Breast Cancer Res Treat , vol.132 , Issue.2 , pp. 545-553
    • Mahmoud, S.M.1    Lee, A.H.2    Paish, E.C.3    Macmillan, R.D.4    Ellis, I.O.5    Green, A.R.6
  • 32
    • 78149488860 scopus 로고    scopus 로고
    • CD20 + B cells: The other tumor-infiltrating lymphocytes
    • doi:10.4049/jimmu nol.1001323
    • Nelson BH (2010) CD20 + B cells: the other tumor-infiltrating lymphocytes. J Immunol 185(9):4977-4982. doi:10.4049/jimmu nol.1001323
    • (2010) J Immunol , vol.185 , Issue.9 , pp. 4977-4982
    • Nelson, B.H.1
  • 35
    • 77950070632 scopus 로고    scopus 로고
    • Effector and regulatory B cells: Modulators of CD4(+) T cell immunity
    • doi:10.1038/nri2729
    • Lund FE, Randall TD (2010) Effector and regulatory B cells: modulators of CD4(+) T cell immunity. Nat Rev Immunol 10(4):236-247. doi:10.1038/nri2729
    • (2010) Nat Rev Immunol , vol.10 , Issue.4 , pp. 236-247
    • Lund, F.E.1    Randall, T.D.2
  • 36
    • 37549027159 scopus 로고    scopus 로고
    • Innate responses of B cells
    • doi:10.1002/eji.200737728
    • Gray D, Gray M, Barr T (2007) Innate responses of B cells. Eur J Immunol 37(12):3304-3310. doi:10.1002/eji.200737728
    • (2007) Eur J Immunol , vol.37 , Issue.12 , pp. 3304-3310
    • Gray, D.1    Gray, M.2    Barr, T.3
  • 38
  • 39
    • 84878916130 scopus 로고    scopus 로고
    • B-regulatory cells in autoimmunity and immune mediated inflammation
    • doi:10.1016/j.febslet.2013.05.023
    • Vadasz Z, Haj T, Kessel A, Toubi E (2013) B-regulatory cells in autoimmunity and immune mediated inflammation. FEBS Lett 587(13):2074-2078. doi:10.1016/j.febslet.2013.05.023
    • (2013) FEBS Lett , vol.587 , Issue.13 , pp. 2074-2078
    • Vadasz, Z.1    Haj, T.2    Kessel, A.3    Toubi, E.4
  • 40
    • 84861666266 scopus 로고    scopus 로고
    • Tertiary lymphoid organs in infection and autoimmunity
    • doi:10.1016/j.it.2012.04.006
    • Neyt K, Perros F, GeurtsvanKessel CH, Hammad H, Lambrecht BN (2012) Tertiary lymphoid organs in infection and autoimmunity. Trends Immunol 33(6):297-305. doi:10.1016/j.it.2012.04.006
    • (2012) Trends Immunol , vol.33 , Issue.6 , pp. 297-305
    • Neyt, K.1    Perros, F.2    GeurtsvanKessel, C.H.3    Hammad, H.4    Lambrecht, B.N.5
  • 41
    • 0035504918 scopus 로고    scopus 로고
    • Evidence for an antigen-driven humoral immune response in medullary ductal breast cancer
    • Coronella JA, Telleman P, Kingsbury GA, Truong TD, Hays S, Junghans RP (2001) Evidence for an antigen-driven humoral immune response in medullary ductal breast cancer. Cancer Res 61(21):7889-7899 (Pubitemid 33050986)
    • (2001) Cancer Research , vol.61 , Issue.21 , pp. 7889-7899
    • Coronella, J.A.1    Telleman, P.2    Kingsbury, G.A.3    Truong, T.D.4    Hays, S.5    Junghans, R.P.6
  • 42
    • 0037103334 scopus 로고    scopus 로고
    • Antigen-driven oligoclonal expansion of tumor-infiltrating B cells in infiltrating ductal carcinoma of the breast
    • Coronella JA, Spier C, Welch M, Trevor KT, Stopeck AT, Villar H, Hersh EM (2002) Antigen-driven oligoclonal expansion of tumor-infiltrating B cells in infiltrating ductal carcinoma of the breast. J Immunol 169(4):1829-1836 (Pubitemid 34857644)
    • (2002) Journal of Immunology , vol.169 , Issue.4 , pp. 1829-1836
    • Coronella, J.A.1    Spier, C.2    Welch, M.3    Trevor, K.T.4    Stopeck, A.T.5    Villar, H.6    Hersh, E.M.7
  • 43
    • 0036721786 scopus 로고    scopus 로고
    • Translocation of an intracellular antigen to the surface of medullary breast cancer cells early in apoptosis allows for an antigen-driven antibody response elicited by tumor-infiltrating B cells
    • Hansen MH, Nielsen HV, Ditzel HJ (2002) Translocation of an intracellular antigen to the surface of medullary breast cancer cells early in apoptosis allows for an antigen-driven antibody response elicited by tumor-infiltrating B cells. J Immunol 169(5):2701-2711 (Pubitemid 34921019)
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2701-2711
    • Hansen, M.H.1    Nielsen, H.V.2    Ditzel, H.J.3
  • 44
    • 0035940459 scopus 로고    scopus 로고
    • The tumor-infiltrating B cell response in medullary breast cancer is oligoclonal and directed against the autoantigen actin exposed on the surface of apoptotic cancer cells
    • DOI 10.1073/pnas.171460798
    • Hansen MH, Nielsen H, Ditzel HJ (2001) The tumor-infiltrating B cell response in medullary breast cancer is oligoclonal and directed against the autoantigen actin exposed on the surface of apoptotic cancer cells. Proc Natl Acad Sci USA 98(22):12659-12664. doi:10.1073/pnas.171460798 (Pubitemid 33020002)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.22 , pp. 12659-12664
    • Hansen, M.H.1    Nielsen, H.2    Ditzel, H.J.3
  • 45
    • 0038407404 scopus 로고    scopus 로고
    • Antigen-driven clonal proliferation, somatic hypermutation, and selection of B lymphocytes infiltrating human ductal breast carcinomas
    • Nzula S, Going JJ, Stott DI (2003) Antigen-driven clonal proliferation, somatic hypermutation, and selection of B lymphocytes infiltrating human ductal breast carcinomas. Cancer Res 63(12):3275-3280 (Pubitemid 36735883)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3275-3280
    • Nzula, S.1    Going, J.J.2    Stott, D.I.3
  • 47
    • 22844442492 scopus 로고    scopus 로고
    • Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: The proof of principle concerning the tumor-infiltrating B lymphocytes
    • Kotlan B, Simsa P, Teillaud JL, Fridman WH, Toth J, McKnight M, Glassy MC (2005) Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: the proof of principle concerning the tumor-infiltrating B lymphocytes. J Immunol 175(4):2278-2285 (Pubitemid 41113835)
    • (2005) Journal of Immunology , vol.175 , Issue.4 , pp. 2278-2285
    • Kotlan, B.1    Simsa, P.2    Teillaud, J.-L.3    Fridman, W.H.4    Toth, J.5    McKnight, M.6    Glassy, M.C.7
  • 48
    • 22844448548 scopus 로고    scopus 로고
    • Tumor-infiltrating B cell immunoglobulin variable region gene usage in invasive ductal breast carcinoma
    • Simsa P, Teillaud JL, Stott DI, Toth J, Kotlan B (2005) Tumor-infiltrating B cell immunoglobulin variable region gene usage in invasive ductal breast carcinoma. Pathol Oncol Res 11(2):92-97 (Pubitemid 41039445)
    • (2005) Pathology Oncology Research , vol.11 , Issue.2 , pp. 92-97
    • Simsa, P.1    Teillaud, J.-L.2    Stott, D.I.3    Toth, J.4    Kotlan, B.5
  • 49
    • 84857681294 scopus 로고    scopus 로고
    • Ex-vivo clonally expanded B lymphocytes infiltrating colorectal carcinoma are of mature immunophenotype and produce functional IgG
    • doi:10.1371/journal.pone.0032639
    • Maletzki C, Jahnke A, Ostwald C, Klar E, Prall F, Linnebacher M (2012) Ex-vivo clonally expanded B lymphocytes infiltrating colorectal carcinoma are of mature immunophenotype and produce functional IgG. PLoS ONE 7(2):e32639. doi:10.1371/journal.pone.0032639
    • (2012) PLoS ONE , vol.7 , Issue.2
    • Maletzki, C.1    Jahnke, A.2    Ostwald, C.3    Klar, E.4    Prall, F.5    Linnebacher, M.6
  • 50
  • 52
    • 0037086272 scopus 로고    scopus 로고
    • Tumor-infiltrating B lymphocytes as a potential source of identifying tumor antigen in human lung cancer
    • Yasuda M, Takenoyama M, Obata Y, Sugaya M, So T, Hanagiri T, Sugio K, Yasumoto K (2002) Tumor-infiltrating B lymphocytes as a potential source of identifying tumor antigen in human lung cancer. Cancer Res 62(6):1751-1756 (Pubitemid 34408498)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1751-1756
    • Yasuda, M.1    Takenoyama, M.2    Obata, Y.3    Sugaya, M.4    So, T.5    Hanagiri, T.6    Sugio, K.7    Yasumoto, K.8
  • 54
    • 17144428600 scopus 로고    scopus 로고
    • In situ isolation of immunoglobulin sequences expressed by single tumor-infiltrating B cells using laser-assisted microdissection
    • O'Brien PM, Millan DW, Davis JA, Campo MS (2005) In situ isolation of immunoglobulin sequences expressed by single tumor-infiltrating B cells using laser-assisted microdissection. Mol Biotechnol 29(2):101-109
    • (2005) Mol Biotechnol , vol.29 , Issue.2 , pp. 101-109
    • O'Brien, P.M.1    Millan, D.W.2    Davis, J.A.3    Campo, M.S.4
  • 56
    • 0026621874 scopus 로고
    • Analysis of two human monoclonal antibodies against melanoma
    • DOI 10.1002/ijc.2910520623
    • Yeilding NM, Gerstner C, Kirkwood JM (1992) Analysis of two human monoclonal antibodies against melanoma. Int J Cancer 52(6):967-973 (Pubitemid 23009517)
    • (1992) International Journal of Cancer , vol.52 , Issue.6 , pp. 967-973
    • Yeilding, N.M.1    Gerstner, C.2    Kirkwood, J.M.3
  • 57
    • 0029112871 scopus 로고
    • A human monoclonal antimelanoma singlechain Fv antibody derived from tumor-infiltrating lymphocytes
    • Zhang H, Lake DF, Barbuto JA, Bernstein RM, Grimes WJ, Hersh EM (1995) A human monoclonal antimelanoma singlechain Fv antibody derived from tumor-infiltrating lymphocytes. Cancer Res 55(16):3584-3591
    • (1995) Cancer Res , vol.55 , Issue.16 , pp. 3584-3591
    • Zhang, H.1    Lake, D.F.2    Barbuto, J.A.3    Bernstein, R.M.4    Grimes, W.J.5    Hersh, E.M.6
  • 58
    • 0018765463 scopus 로고
    • Distribution of T- and B-cells and of immunoglobulin-producing cells in tumor tissue of patients with nasopharyngeal carcinoma
    • DOI 10.1007/BF00406578
    • Konorza G, Sesterhenn K, Krueger GR, Ablashi DV (1979) Distribution of T- and B-cells and of immunoglobulin-producing cells in tumor tissue of patients with nasopharyngeal carcinoma. J Cancer Res Clin Oncol 93(2):195-204 (Pubitemid 9175404)
    • (1979) Journal of Cancer Research and Clinical Oncology , vol.93 , Issue.2 , pp. 195-204
    • Konorza, G.1    Sesterhenn, K.2    Krueger, G.R.F.3    Ablashi, D.V.4
  • 59
    • 67449098379 scopus 로고    scopus 로고
    • Malignant mesothelioma-associated antigens recognized by tumor-infiltrating B cells and the clinical significance of the antibody titers
    • doi:10.1111/j.1349-7006.2009.01181.x
    • Shigematsu Y, Hanagiri T, Kuroda K, Baba T, Mizukami M, Ichiki Y, Yasuda M, Takenoyama M, Sugio K, Yasumoto K (2009) Malignant mesothelioma-associated antigens recognized by tumor-infiltrating B cells and the clinical significance of the antibody titers. Cancer Sci 100(7):1326-1334. doi:10.1111/j.1349-7006. 2009.01181.x
    • (2009) Cancer Sci , vol.100 , Issue.7 , pp. 1326-1334
    • Shigematsu, Y.1    Hanagiri, T.2    Kuroda, K.3    Baba, T.4    Mizukami, M.5    Ichiki, Y.6    Yasuda, M.7    Takenoyama, M.8    Sugio, K.9    Yasumoto, K.10
  • 61
    • 84878069933 scopus 로고    scopus 로고
    • Multiplex B cell characterization in blood, lymph nodes, and tumors from patients with malignancies
    • doi:10.4049/jimmunol.1203279
    • Zirakzadeh AA, Marits P, Sherif A, Winqvist O (2013) Multiplex B cell characterization in blood, lymph nodes, and tumors from patients with malignancies. J Immunol 190(11):5847-5855. doi:10.4049/jimmunol.1203279
    • (2013) J Immunol , vol.190 , Issue.11 , pp. 5847-5855
    • Zirakzadeh, A.A.1    Marits, P.2    Sherif, A.3    Winqvist, O.4
  • 65
    • 68549106119 scopus 로고    scopus 로고
    • A systematic review of humoral immune responses against tumor antigens
    • doi:10.1007/s00262-009-0733-4
    • Reuschenbach M, von Knebel Doeberitz M, Wentzensen N (2009) A systematic review of humoral immune responses against tumor antigens. Cancer Immunol Immunother 58(10):1535-1544. doi:10.1007/s00262-009-0733-4
    • (2009) Cancer Immunol Immunother , vol.58 , Issue.10 , pp. 1535-1544
    • Reuschenbach, M.1    Von Knebel Doeberitz, M.2    Wentzensen, N.3
  • 67
    • 79952216352 scopus 로고    scopus 로고
    • Prognostic and diagnostic value of spontaneous tumor-related antibodies
    • doi:10.1155/2010/721531
    • Kobold S, Luetkens T, Cao Y, Bokemeyer C, Atanackovic D (2010) Prognostic and diagnostic value of spontaneous tumor-related antibodies. Clin Dev Immunol. doi:10.1155/2010/721531
    • (2010) Clin Dev Immunol
    • Kobold, S.1    Luetkens, T.2    Cao, Y.3    Bokemeyer, C.4    Atanackovic, D.5
  • 68
    • 2442666480 scopus 로고    scopus 로고
    • NY-ESO-I protein expression and humoral immune responses in prostate cancer
    • DOI 10.1002/pros.20025
    • Fossa A, Berner A, Fossa SD, Hernes E, Gaudernack G, Smeland EB (2004) NY-ESO-1 protein expression and humoral immune responses in prostate cancer. Prostate 59(4):440-447 (Pubitemid 38661812)
    • (2004) Prostate , vol.59 , Issue.4 , pp. 440-447
    • Fossa, A.1    Berner, A.2    Fossa, S.D.3    Hernes, E.4    Gaudernack, G.5    Smeland, E.B.6
  • 70
    • 84881053737 scopus 로고    scopus 로고
    • Clinical utility of anti-p53 auto-antibody: Systematic review and focus on colorectal cancer
    • doi:10.3748/wjg.v19.i29.4651
    • Suppiah A, Greenman J (2013) Clinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancer. World J Gastroenterol 19(29):4651-4670. doi:10.3748/wjg.v19.i29.4651
    • (2013) World J Gastroenterol , vol.19 , Issue.29 , pp. 4651-4670
    • Suppiah, A.1    Greenman, J.2
  • 71
    • 85034700931 scopus 로고    scopus 로고
    • Autoantibody biomarkers for early detection and prognosis of gastric cancer
    • 15th international congress of immunology (ICI), Milan, Italy, 22 Aug 2013. conference abstract. doi:10.3389/conf.fimmu.2013.02.01082
    • Silina KZP, Ancans G, Kalnina Z, Meistere I, Pismennaya A, Leja M, Line A (2013) Autoantibody biomarkers for early detection and prognosis of gastric cancer. In: 15th international congress of immunology (ICI), Milan, Italy, 22 Aug 2013. Front Immunol conference abstract. doi:10.3389/conf.fimmu.2013.02. 01082
    • (2013) Front Immunol
    • Silina, K.Z.P.1    Ancans, G.2    Kalnina, Z.3    Meistere, I.4    Pismennaya, A.5    Leja, M.6    Line, A.7
  • 72
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • doi:10.1038/nri2206
    • Nimmerjahn F, Ravetch JV (2008) Fcgamma receptors as regulators of immune responses. Nat Rev Immunol 8(1):34-47. doi:10.1038/nri2206
    • (2008) Nat Rev Immunol , vol.8 , Issue.1 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 75
    • 54749087862 scopus 로고    scopus 로고
    • Autoantibody profiles as biomarkers for response to therapy and early detection of cancer
    • doi:10.2174/157339408784310160
    • Kalnina Z, Silina K, Line A (2008) Autoantibody profiles as biomarkers for response to therapy and early detection of cancer. Curr Canc Ther Rev 4(2):149-156. doi:10.2174/157339408784310160
    • (2008) Curr Canc Ther Rev , vol.4 , Issue.2 , pp. 149-156
    • Kalnina, Z.1    Silina, K.2    Line, A.3
  • 77
    • 84871582535 scopus 로고    scopus 로고
    • Impact of CD68/(CD3+CD20) ratio at the invasive front of primary tumors on distant metastasis development in breast cancer
    • doi:10.1371/journal.pone.0052796
    • Eiro N, Pidal I, Fernandez-Garcia B, Junquera S, Lamelas ML, del Casar JM, Gonzalez LO, Lopez-Muniz A, Vizoso FJ (2012) Impact of CD68/(CD3+CD20) ratio at the invasive front of primary tumors on distant metastasis development in breast cancer. PLoS ONE 7(12):e52796. doi:10.1371/journal.pone.0052796
    • (2012) PLoS ONE , vol.7 , Issue.12
    • Eiro, N.1    Pidal, I.2    Fernandez-Garcia, B.3    Junquera, S.4    Lamelas, M.L.5    Del Casar, J.M.6    Gonzalez, L.O.7    Lopez-Muniz, A.8    Vizoso, F.J.9
  • 78
    • 84862557227 scopus 로고    scopus 로고
    • CD20+ tumor-infiltrating lymphocytes have an atypical CD27- memory phenotype and together with CD8+ T cells promote favorable prognosis in ovarian cancer
    • doi:10.1158/1078-0432.CCR-12-0234
    • Nielsen JS, Sahota RA, Milne K, Kost SE, Nesslinger NJ, Watson PH, Nelson BH (2012) CD20+ tumor-infiltrating lymphocytes have an atypical CD27- memory phenotype and together with CD8+ T cells promote favorable prognosis in ovarian cancer. Clin Cancer Res 18(12):3281-3292. doi:10.1158/1078-0432.CCR-12-0234
    • (2012) Clin Cancer Res , vol.18 , Issue.12 , pp. 3281-3292
    • Nielsen, J.S.1    Sahota, R.A.2    Milne, K.3    Kost, S.E.4    Nesslinger, N.J.5    Watson, P.H.6    Nelson, B.H.7
  • 79
    • 68149141666 scopus 로고    scopus 로고
    • Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors
    • doi:10.1371/journal.pone.0006412
    • Milne K, Kobel M, Kalloger SE, Barnes RO, Gao D, Gilks CB, Watson PH, Nelson BH (2009) Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors. PLoS ONE 4(7):e6412. doi:10.1371/journal.pone.0006412
    • (2009) PLoS ONE , vol.4 , Issue.7
    • Milne, K.1    Kobel, M.2    Kalloger, S.E.3    Barnes, R.O.4    Gao, D.5    Gilks, C.B.6    Watson, P.H.7    Nelson, B.H.8
  • 81
    • 80053633053 scopus 로고    scopus 로고
    • Prognostic effect of stromal lymphocyte infiltration in thymic carcinoma
    • doi:10.1016/j.lungcan.2011.03.008
    • Shim HS, Byun CS, Bae MK, Lee CY, Park IK, Kim DJ, Chung KY, Lee JG (2011) Prognostic effect of stromal lymphocyte infiltration in thymic carcinoma. Lung Cancer 74(2):338-343. doi:10.1016/j.lungcan.2011.03.008
    • (2011) Lung Cancer , vol.74 , Issue.2 , pp. 338-343
    • Shim, H.S.1    Byun, C.S.2    Bae, M.K.3    Lee, C.Y.4    Park, I.K.5    Kim, D.J.6    Chung, K.Y.7    Lee, J.G.8
  • 83
    • 33646036416 scopus 로고    scopus 로고
    • B cells as antigen presenting cells
    • doi:10.1016/j.cellimm.2006.02.005
    • Rodriguez-Pinto D (2005) B cells as antigen presenting cells. Cell Immunol 238(2):67-75. doi:10.1016/j.cellimm.2006.02.005
    • (2005) Cell Immunol , vol.238 , Issue.2 , pp. 67-75
    • Rodriguez-Pinto, D.1
  • 84
    • 42149097910 scopus 로고    scopus 로고
    • CD40 Ligand-activated, antigen-specific B cells are comparable to mature dendritic cells in presenting protein antigens and major histocompatibility complex class I- and class II-binding peptides
    • DOI 10.1111/j.1365-2567.2007.02749.x
    • Ahmadi T, Flies A, Efebera Y, Sherr DH (2008) CD40 Ligand-activated, antigen-specific B cells are comparable to mature dendritic cells in presenting protein antigens and major histocompatibility complex class I- and class II-binding peptides. Immunology 124(1):129-140. doi:10.1111/j.1365-2567.2007. 02749.x (Pubitemid 351537580)
    • (2008) Immunology , vol.124 , Issue.1 , pp. 129-140
    • Ahmadi, T.1    Flies, A.2    Efebera, Y.3    Sherr, D.H.4
  • 85
    • 77958607779 scopus 로고    scopus 로고
    • Antigen-specific B cells reactivate an effective cytotoxic T cell response against phagocytosed Salmonella through cross-presentation
    • doi:10.1371/journal.pone.0013016
    • de Wit J, Souwer Y, Jorritsma T, Klaasse Bos H, ten Brinke A, Neefjes J, van Ham SM (2010) Antigen-specific B cells reactivate an effective cytotoxic T cell response against phagocytosed Salmonella through cross-presentation. PLoS ONE 5(9):e13016. doi:10.1371/journal.pone.0013016
    • (2010) PLoS ONE , vol.5 , Issue.9
    • De Wit, J.1    Souwer, Y.2    Jorritsma, T.3    Klaasse Bos, H.4    Ten Brinke, A.5    Neefjes, J.6    Van Ham, S.M.7
  • 87
    • 84883244497 scopus 로고    scopus 로고
    • Tumor-infiltrating B cells and T cells: Working together to promote patient survival
    • doi:10.4161/onci.21650
    • Nielsen JS, Nelson BH (2012) Tumor-infiltrating B cells and T cells: working together to promote patient survival. Oncoimmunology 1(9):1623-1625. doi:10.4161/onci.21650
    • (2012) Oncoimmunology , vol.1 , Issue.9 , pp. 1623-1625
    • Nielsen, J.S.1    Nelson, B.H.2
  • 89
    • 70349412916 scopus 로고    scopus 로고
    • A double-negative (IgD-CD27-) B cell population is increased in the peripheral blood of elderly people
    • doi:10.1016/j.mad.2009.08.003
    • Colonna-Romano G, Bulati M, Aquino A, Pellicano M, Vitello S, Lio D, Candore G, Caruso C (2009) A double-negative (IgD-CD27-) B cell population is increased in the peripheral blood of elderly people. Mech Ageing Dev 130(10):681-690. doi:10.1016/j.mad.2009.08.003
    • (2009) Mech Ageing Dev , vol.130 , Issue.10 , pp. 681-690
    • Colonna-Romano, G.1    Bulati, M.2    Aquino, A.3    Pellicano, M.4    Vitello, S.5    Lio, D.6    Candore, G.7    Caruso, C.8
  • 90
    • 77952817885 scopus 로고    scopus 로고
    • Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients
    • doi:10.1186/ar3042
    • Rodriguez-Bayona B, Ramos-Amaya A, Perez-Venegas JJ, Rodriguez C, Brieva JA (2010) Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients. Arthritis Res Ther 12(3):R108. doi:10.1186/ar3042
    • (2010) Arthritis Res Ther , vol.12 , Issue.3
    • Rodriguez-Bayona, B.1    Ramos-Amaya, A.2    Perez-Venegas, J.J.3    Rodriguez, C.4    Brieva, J.A.5
  • 91
    • 34248140178 scopus 로고    scopus 로고
    • A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus
    • Wei C, Anolik J, Cappione A, Zheng B, Pugh-Bernard A, Brooks J, Lee EH, Milner EC, Sanz I (2007) A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. J Immunol 178(10):6624-6633 (Pubitemid 46717447)
    • (2007) Journal of Immunology , vol.178 , Issue.10 , pp. 6624-6633
    • Wei, C.1    Anolik, J.2    Cappione, A.3    Zheng, B.4    Pugh-Bernard, A.5    Brooks, J.6    Lee, E.-H.7    Milner, E.C.B.8    Sanz, I.9
  • 94
    • 39649095149 scopus 로고    scopus 로고
    • Phenotypic and functional heterogeneity of human memory B cells
    • doi:10.1016/j.smim.2007.12.006
    • Sanz I, Wei C, Lee FE, Anolik J (2008) Phenotypic and functional heterogeneity of human memory B cells. Semin Immunol 20(1):67-82. doi:10.1016/j.smim.2007.12.006
    • (2008) Semin Immunol , vol.20 , Issue.1 , pp. 67-82
    • Sanz, I.1    Wei, C.2    Lee, F.E.3    Anolik, J.4
  • 95
    • 79960975784 scopus 로고    scopus 로고
    • Adoptive transfer of tumor reactive B cells confers host T-cell immunity and tumor regression
    • doi:10.1158/1078-0432.CCR-11-0207
    • Li Q, Lao X, Pan Q, Ning N, Yet J, Xu Y, Li S, Chang AE (2011) Adoptive transfer of tumor reactive B cells confers host T-cell immunity and tumor regression. Clin Cancer Res 17(15):4987-4995. doi:10.1158/1078-0432.CCR-11-0207
    • (2011) Clin Cancer Res , vol.17 , Issue.15 , pp. 4987-4995
    • Li, Q.1    Lao, X.2    Pan, Q.3    Ning, N.4    Yet, J.5    Xu, Y.6    Li, S.7    Chang, A.E.8
  • 96
    • 3142757918 scopus 로고    scopus 로고
    • Human B cells express functional TRAIL/Apo-2 ligand after CpG-containing oligodeoxynucleotide stimulation
    • Kemp TJ, Moore JM, Griffith TS (2004) Human B cells express functional TRAIL/Apo-2 ligand after CpG-containing oligodeoxynucleotide stimulation. J Immunol 173(2):892-899 (Pubitemid 38924262)
    • (2004) Journal of Immunology , vol.173 , Issue.2 , pp. 892-899
    • Kemp, T.J.1    Moore, J.M.2    Griffith, T.S.3
  • 99
    • 84886943331 scopus 로고    scopus 로고
    • Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway
    • doi:10.4161/onci.22354
    • Hagn M, Jahrsdorfer B (2012) Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway. Oncoimmunology 1(8):1368-1375. doi:10.4161/onci.22354
    • (2012) Oncoimmunology , vol.1 , Issue.8 , pp. 1368-1375
    • Hagn, M.1    Jahrsdorfer, B.2
  • 101
    • 84857025735 scopus 로고    scopus 로고
    • Multiple mechanisms of immune suppression by B lymphocytes
    • doi:10.2119/molmed.2011.00333
    • Klinker MW, Lundy SK (2012) Multiple mechanisms of immune suppression by B lymphocytes. Mol Med 18:123-137. doi:10.2119/molmed.2011.00333
    • (2012) Mol Med , vol.18 , pp. 123-137
    • Klinker, M.W.1    Lundy, S.K.2
  • 104
    • 80555124922 scopus 로고    scopus 로고
    • Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice
    • doi:10.1172/JCI59266
    • Horikawa M, Minard-Colin V, Matsushita T, Tedder TF (2011) Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice. J Clin Invest 121(11):4268-4280. doi:10.1172/JCI59266
    • (2011) J Clin Invest , vol.121 , Issue.11 , pp. 4268-4280
    • Horikawa, M.1    Minard-Colin, V.2    Matsushita, T.3    Tedder, T.F.4
  • 105
    • 84885451683 scopus 로고    scopus 로고
    • Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells
    • doi:10.4049/jimmunol.1300606
    • Lee-Chang C, Bodogai M, Martin-Montalvo A, Wejksza K, Sanghvi M, Moaddel R, de Cabo R, Biragyn A (2013) Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells. J Immunol 191(8):4141-4151. doi:10.4049/jimmunol.1300606
    • (2013) J Immunol , vol.191 , Issue.8 , pp. 4141-4151
    • Lee-Chang, C.1    Bodogai, M.2    Martin-Montalvo, A.3    Wejksza, K.4    Sanghvi, M.5    Moaddel, R.6    De Cabo, R.7    Biragyn, A.8
  • 106
    • 84876008718 scopus 로고    scopus 로고
    • Anti-CD20 antibody promotes cancer escape via enrichment of tumor-evoked regulatory B cells expressing low levels of CD20 and CD137L
    • doi:10.1158/0008-5472.CAN-12-4184
    • Bodogai M, Lee Chang C, Wejksza K, Lai J, Merino M, Wersto RP, Gress RE, Chan AC, Hesdorffer C, Biragyn A (2013) Anti-CD20 antibody promotes cancer escape via enrichment of tumor-evoked regulatory B cells expressing low levels of CD20 and CD137L. Cancer Res 73(7):2127-2138. doi:10.1158/0008-5472.CAN-12- 4184
    • (2013) Cancer Res , vol.73 , Issue.7 , pp. 2127-2138
    • Bodogai, M.1    Lee Chang, C.2    Wejksza, K.3    Lai, J.4    Merino, M.5    Wersto, R.P.6    Gress, R.E.7    Chan, A.C.8    Hesdorffer, C.9    Biragyn, A.10
  • 107
    • 80051484018 scopus 로고    scopus 로고
    • B lymphocytes promote lymphogenous metastasis of lymphoma and melanoma
    • Ruddell A, Harrell MI, Furuya M, Kirschbaum SB, Iritani BM (2011) B lymphocytes promote lymphogenous metastasis of lymphoma and melanoma. Neoplasia 13(8):748-757
    • (2011) Neoplasia , vol.13 , Issue.8 , pp. 748-757
    • Ruddell, A.1    Harrell, M.I.2    Furuya, M.3    Kirschbaum, S.B.4    Iritani, B.M.5
  • 110
    • 77949379050 scopus 로고    scopus 로고
    • B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
    • doi:10.1038/nature08782
    • Ammirante M, Luo JL, Grivennikov S, Nedospasov S, Karin M (2010) B-cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 464(7286):302-305. doi:10.1038/nature08782
    • (2010) Nature , vol.464 , Issue.7286 , pp. 302-305
    • Ammirante, M.1    Luo, J.L.2    Grivennikov, S.3    Nedospasov, S.4    Karin, M.5
  • 111
    • 84879757412 scopus 로고    scopus 로고
    • An IKKal-pha-E2F1-BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence
    • doi:10.1101/gad.220202.113
    • Ammirante M, Kuraishy AI, Shalapour S, Strasner A, Ramirez-Sanchez C, Zhang W, Shabaik A, Karin M (2013) An IKKal-pha-E2F1-BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence. Genes Dev 27(13):1435-1440. doi:10.1101/gad.220202.113
    • (2013) Genes Dev , vol.27 , Issue.13 , pp. 1435-1440
    • Ammirante, M.1    Kuraishy, A.I.2    Shalapour, S.3    Strasner, A.4    Ramirez-Sanchez, C.5    Zhang, W.6    Shabaik, A.7    Karin, M.8
  • 112
    • 68749087029 scopus 로고    scopus 로고
    • Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients
    • doi:10.1016/j.jim.2009.06.004
    • Gannon PO, Poisson AO, Delvoye N, Lapointe R, Mes-Masson AM, Saad F (2009) Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. J Immunol Methods 348(1-2):9-17. doi:10.1016/j.jim.2009.06.004
    • (2009) J Immunol Methods , vol.348 , Issue.1-2 , pp. 9-17
    • Gannon, P.O.1    Poisson, A.O.2    Delvoye, N.3    Lapointe, R.4    Mes-Masson, A.M.5    Saad, F.6
  • 113
    • 84881120542 scopus 로고    scopus 로고
    • Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer
    • doi:10.1371/journal.pone.0071367
    • Koizumi M, Hiasa Y, Kumagi T, Yamanishi H, Azemoto N, Kobata T, Matsuura B, Abe M, Onji M (2013) Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer. PLoS ONE 8(8):e71367. doi:10.1371/journal.pone.0071367
    • (2013) PLoS ONE , vol.8 , Issue.8
    • Koizumi, M.1    Hiasa, Y.2    Kumagi, T.3    Yamanishi, H.4    Azemoto, N.5    Kobata, T.6    Matsuura, B.7    Abe, M.8    Onji, M.9
  • 114
    • 84859381450 scopus 로고    scopus 로고
    • Germinal centers
    • doi:10.1146/annurev-immunol-020711-075032
    • Victora GD, Nussenzweig MC (2012) Germinal centers. Annu Rev Immunol 30:429-457. doi:10.1146/annurev-immunol-020711-075032
    • (2012) Annu Rev Immunol , vol.30 , pp. 429-457
    • Victora, G.D.1    Nussenzweig, M.C.2
  • 115
    • 77956175900 scopus 로고    scopus 로고
    • New insights into the development of lymphoid tissues
    • doi:10.1038/nri2832
    • van de Pavert SA, Mebius RE (2010) New insights into the development of lymphoid tissues. Nat Rev Immunol 10(9):664-674. doi:10.1038/nri2832
    • (2010) Nat Rev Immunol , vol.10 , Issue.9 , pp. 664-674
    • Van De Pavert, S.A.1    Mebius, R.E.2
  • 116
    • 84883207256 scopus 로고    scopus 로고
    • Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis
    • doi:10.1111/imm.12119
    • Kain MJ, Owens BM (2013) Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis. Immunology 140(1):12-21. doi:10.1111/imm.12119
    • (2013) Immunology , vol.140 , Issue.1 , pp. 12-21
    • Kain, M.J.1    Owens, B.M.2
  • 117
    • 84877586473 scopus 로고    scopus 로고
    • Endothelial cell-specific lymphotoxin-beta receptor signaling is critical for lymph node and high endothelial venule formation
    • doi:10.1084/jem.20121462
    • Onder L, Danuser R, Scandella E, Firner S, Chai Q, Hehlgans T, Stein JV, Ludewig B (2013) Endothelial cell-specific lymphotoxin-beta receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 210(3):465-473. doi:10.1084/jem.20121462
    • (2013) J Exp Med , vol.210 , Issue.3 , pp. 465-473
    • Onder, L.1    Danuser, R.2    Scandella, E.3    Firner, S.4    Chai, Q.5    Hehlgans, T.6    Stein, J.V.7    Ludewig, B.8
  • 118
    • 17844376798 scopus 로고    scopus 로고
    • Adaptive immune responses are dispensable for isolated lymphoid follicle formation: Antigen-naive, lymphotoxin-sufficient B lymphocytes drive the formation of mature isolated lymphoid follicles
    • McDonald KG, McDonough JS, Newberry RD (2005) Adaptive immune responses are dispensable for isolated lymphoid follicle formation: antigen-naive, lymphotoxin-sufficient B lymphocytes drive the formation of mature isolated lymphoid follicles. J Immunol 174(9):5720-5728 (Pubitemid 40593215)
    • (2005) Journal of Immunology , vol.174 , Issue.9 , pp. 5720-5728
    • McDonald, K.G.1    McDonough, J.S.2    Newberry, R.D.3
  • 119
    • 34247859190 scopus 로고    scopus 로고
    • CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles
    • DOI 10.2353/ajpath.2007.060817
    • McDonald KG, McDonough JS, Wang C, Kucharzik T, Williams IR, Newberry RD (2007) CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles. Am J Pathol 170(4):1229-1240. doi:10.2353/ajpath.2007.060817 (Pubitemid 47339331)
    • (2007) American Journal of Pathology , vol.170 , Issue.4 , pp. 1229-1240
    • McDonald, K.G.1    McDonough, J.S.2    Wang, C.3    Kucharzik, T.4    Williams, I.R.5    Newberry, R.D.6
  • 120
    • 70350649131 scopus 로고    scopus 로고
    • CXCL13 expression in the gut promotes accumulation of IL-22-producing lymphoid tissue-inducer cells, and formation of isolated lymphoid follicles
    • doi:10.1038/mi.2009.113
    • Marchesi F, Martin AP, Thirunarayanan N, Devany E, Mayer L, Grisotto MG, Furtado GC, Lira SA (2009) CXCL13 expression in the gut promotes accumulation of IL-22-producing lymphoid tissue-inducer cells, and formation of isolated lymphoid follicles. Mucosal Immunol 2(6):486-494. doi:10.1038/mi.2009.113
    • (2009) Mucosal Immunol , vol.2 , Issue.6 , pp. 486-494
    • Marchesi, F.1    Martin, A.P.2    Thirunarayanan, N.3    Devany, E.4    Mayer, L.5    Grisotto, M.G.6    Furtado, G.C.7    Lira, S.A.8
  • 122
    • 0029980743 scopus 로고    scopus 로고
    • Involvement of B lymphocytes in the growth inhibition of human pulmonary melanoma metastases in athymic nu/nu mice by an antibody-lymphotoxin fusion protein
    • Reisfeld RA, Gillies SD, Mendelsohn J, Varki NM, Becker JC (1996) Involvement of B lymphocytes in the growth inhibition of human pulmonary melanoma metastases in athymic nu/nu mice by an antibody-lymphotoxin fusion protein. Cancer Res 56(8):1707-1712 (Pubitemid 26118200)
    • (1996) Cancer Research , vol.56 , Issue.8 , pp. 1707-1712
    • Reisfeld, R.A.1    Gillies, S.D.2    Mendelsohn, J.3    Varki, N.M.4    Becker, J.C.5
  • 123
    • 0035102225 scopus 로고    scopus 로고
    • Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue
    • Schrama D, Thor Straten P, Fischer WH, McLellan AD, Brocker EB, Reisfeld RA, Becker JC (2001) Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue. Immunity 14(2):111-121 (Pubitemid 32206514)
    • (2001) Immunity , vol.14 , Issue.2 , pp. 111-121
    • Schrama, D.1    Thor, S.P.2    Fischer, W.H.3    McLellan, A.D.4    Brocker, E.-B.5    Reisfeld, R.A.6    Becker, J.C.7
  • 124
    • 1642404586 scopus 로고    scopus 로고
    • Establishment of Early Lymphoid Organ Infrastructure in Transplanted Tumors Mediated by Local Production of Lymphotoxin alpha and in the Combined Absence of Functional B and T Cells
    • Kim HJ, Kammertoens T, Janke M, Schmetzer O, Qin Z, Berek C, Blankenstein T (2004) Establishment of early lymphoid organ infrastructure in transplanted tumors mediated by local production of lymphotoxin alpha and in the combined absence of functional B and T cells. J Immunol 172(7):4037-4047 (Pubitemid 38375215)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4037-4047
    • Kim, H.-J.1    Kammertoens, T.2    Janke, M.3    Schmetzer, O.4    Qin, Z.5    Berek, C.6    Blankenstein, T.7
  • 125
    • 80054037203 scopus 로고    scopus 로고
    • Characterization of chemokines and adhesion molecules associated with T cell presence in tertiary lymphoid structures in human lung cancer
    • doi:10.1158/0008-5472.CAN-11-0952
    • de Chaisemartin L, Goc J, Damotte D, Validire P, Magdeleinat P, Alifano M, Cremer I, Fridman WH, Sautes-Fridman C, Dieu-Nosjean MC (2011) Characterization of chemokines and adhesion molecules associated with T cell presence in tertiary lymphoid structures in human lung cancer. Cancer Res 71(20):6391-6399. doi:10.1158/0008-5472.CAN-11-0952
    • (2011) Cancer Res , vol.71 , Issue.20 , pp. 6391-6399
    • De Chaisemartin, L.1    Goc, J.2    Damotte, D.3    Validire, P.4    Magdeleinat, P.5    Alifano, M.6    Cremer, I.7    Fridman, W.H.8    Sautes-Fridman, C.9    Dieu-Nosjean, M.C.10
  • 126
    • 80052512017 scopus 로고    scopus 로고
    • Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling
    • doi:10.1016/j.ajpath.2011.03.007
    • Coppola D, Nebozhyn M, Khalil F, Dai H, Yeatman T, Loboda A, Mule JJ (2011) Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling. Am J Pathol 179(1):37-45. doi:10.1016/j.ajpath.2011.03.007
    • (2011) Am J Pathol , vol.179 , Issue.1 , pp. 37-45
    • Coppola, D.1    Nebozhyn, M.2    Khalil, F.3    Dai, H.4    Yeatman, T.5    Loboda, A.6    Mule, J.J.7
  • 129
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • DOI 10.1038/nri1786
    • Aloisi F, Pujol-Borrell R (2006) Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol 6(3):205-217. doi:10.1038/nri1786 (Pubitemid 43290990)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 205-217
    • Aloisi, F.1    Pujol-Borrell, R.2
  • 132
    • 78650408306 scopus 로고    scopus 로고
    • Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection
    • doi:10.1002/eji.201040759
    • Brown K, Sacks SH, Wong W (2011) Tertiary lymphoid organs in renal allografts can be associated with donor-specific tolerance rather than rejection. Eur J Immunol 41(1):89-96. doi:10.1002/eji.201040759
    • (2011) Eur J Immunol , vol.41 , Issue.1 , pp. 89-96
    • Brown, K.1    Sacks, S.H.2    Wong, W.3
  • 133
    • 77952231121 scopus 로고    scopus 로고
    • Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21
    • doi:10.1126/science.1185837
    • Shields JD, Kourtis IC, Tomei AA, Roberts JM, Swartz MA (2010) Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21. Science 328(5979):749-752. doi:10.1126/science.1185837
    • (2010) Science , vol.328 , Issue.5979 , pp. 749-752
    • Shields, J.D.1    Kourtis, I.C.2    Tomei, A.A.3    Roberts, J.M.4    Swartz, M.A.5
  • 134
    • 80052969850 scopus 로고    scopus 로고
    • The association of intratumoral germinal centers with early-stage non-small cell lung cancer
    • doi:10.1097/JTO.0b013e3182217bec
    • Gottlin EB, Bentley RC, Campa MJ, Pisetsky DS, Herndon JE 2nd, Patz EF Jr (2011) The association of intratumoral germinal centers with early-stage non-small cell lung cancer. J Thorac Oncol 6(10):1687-1690. doi:10.1097/JTO. 0b013e3182217bec
    • (2011) J Thorac Oncol , vol.6 , Issue.10 , pp. 1687-1690
    • Gottlin, E.B.1    Bentley, R.C.2    Campa, M.J.3    Pisetsky, D.S.4    Herndon II, J.E.5    Patz Jr., E.F.6
  • 135
    • 0031890627 scopus 로고    scopus 로고
    • Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration
    • DOI 10.1002/hep.510270214
    • Wada Y, Nakashima O, Kutami R, Yamamoto O, Kojiro M (1998) Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration. Hepatology 27(2):407-414. doi:10.1002/hep.510270214 (Pubitemid 28081054)
    • (1998) Hepatology , vol.27 , Issue.2 , pp. 407-414
    • Wada, Y.1    Nakashima, O.2    Kutami, R.3    Yamamoto, O.4    Kojiro, M.5
  • 136
    • 84903818924 scopus 로고    scopus 로고
    • Prognostic value of B lymphocyte infiltration in breast cancer
    • Yu H, Yang J, Jiao S, Wang J (2013) Prognostic value of B lymphocyte infiltration in breast cancer. Nan Fang Yi Ke Da Xue Xue Bao 33(5):750-755
    • (2013) Nan Fang Yi Ke Da Xue Xue Bao , vol.33 , Issue.5 , pp. 750-755
    • Yu, H.1    Yang, J.2    Jiao, S.3    Wang, J.4
  • 138
    • 76349111581 scopus 로고    scopus 로고
    • Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction
    • doi:10.1038/ajg.2009.578
    • Ogino S, Nosho K, Irahara N, Shima K, Baba Y, Kirkner GJ, Mino-Kenudson M, Giovannucci EL, Meyerhardt JA, Fuchs CS (2010) Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction. Am J Gastroenterol 105(2):420-433. doi:10.1038/ajg.2009.578
    • (2010) Am J Gastroenterol , vol.105 , Issue.2 , pp. 420-433
    • Ogino, S.1    Nosho, K.2    Irahara, N.3    Shima, K.4    Baba, Y.5    Kirkner, G.J.6    Mino-Kenudson, M.7    Giovannucci, E.L.8    Meyerhardt, J.A.9    Fuchs, C.S.10
  • 141
    • 84881397413 scopus 로고    scopus 로고
    • High endothelial venules (HEVs) in human melanoma lesions: Major gateways for tumorinfiltrating lymphocytes
    • doi:10.4161/onci.20492
    • Martinet L, Le Guellec S, Filleron T, Lamant L, Meyer N, Rochaix P, Garrido I, Girard JP (2012) High endothelial venules (HEVs) in human melanoma lesions: major gateways for tumorinfiltrating lymphocytes. Oncoimmunology 1(6):829-839. doi:10.4161/onci.20492
    • (2012) Oncoimmunology , vol.1 , Issue.6 , pp. 829-839
    • Martinet, L.1    Le Guellec, S.2    Filleron, T.3    Lamant, L.4    Meyer, N.5    Rochaix, P.6    Garrido, I.7    Girard, J.P.8
  • 143
    • 84881421259 scopus 로고    scopus 로고
    • High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin beta-producing dendritic cells in human breast cancer
    • doi:10.4049/jimmunol.1300872
    • Martinet L, Filleron T, Le Guellec S, Rochaix P, Garrido I, Girard JP (2013) High endothelial venule blood vessels for tumor-infiltrating lymphocytes are associated with lymphotoxin beta-producing dendritic cells in human breast cancer. J Immunol 191(4):2001-2008. doi:10.4049/jimmunol.1300872
    • (2013) J Immunol , vol.191 , Issue.4 , pp. 2001-2008
    • Martinet, L.1    Filleron, T.2    Le Guellec, S.3    Rochaix, P.4    Garrido, I.5    Girard, J.P.6
  • 145
    • 84857746620 scopus 로고    scopus 로고
    • Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma
    • doi:10.1158/0008-5472.CAN-11-3218
    • Erdag G, Schaefer JT, Smolkin ME, Deacon DH, Shea SM, Dengel LT, Patterson JW, Slingluff CL Jr (2012) Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma. Cancer Res 72(5):1070-1080. doi:10.1158/0008- 5472.CAN-11-3218
    • (2012) Cancer Res , vol.72 , Issue.5 , pp. 1070-1080
    • Erdag, G.1    Schaefer, J.T.2    Smolkin, M.E.3    Deacon, D.H.4    Shea, S.M.5    Dengel, L.T.6    Patterson, J.W.7    Slingluff Jr., C.L.8
  • 146
    • 0019452821 scopus 로고
    • Treatment of disseminated malignant melanoma with high-dose oral BCG
    • DOI 10.1002/1097-0142(19810915)48:6<1353::AID-CNCR
    • Varella AD, Bandiera DC, de Amorim AR Sr, Calvis LA, Santos IO, Escaleira N, Gentil F (1981) Treatment of disseminated malignant melanoma with high-dose oral BCG. Cancer 48(6):1353-1362 (Pubitemid 11042587)
    • (1981) Cancer , vol.48 , Issue.6 , pp. 1353-1362
    • Varella, A.D.1    Bandiera, D.C.2    De Amorim Sr., A.R.3
  • 147
    • 0035289627 scopus 로고    scopus 로고
    • Changes in mucosal immune cells of bladder tumor patient after BCG intravesical immunotherapy
    • Chang SG, Lee SJ, Huh JS, Lee JH (2001) Changes in mucosal immune cells of bladder tumor patient after BCG intravesical immunotherapy. Oncol Rep 8(2):257-261
    • (2001) Oncol Rep , vol.8 , Issue.2 , pp. 257-261
    • Chang, S.G.1    Lee, S.J.2    Huh, J.S.3    Lee, J.H.4
  • 149
    • 0031056830 scopus 로고    scopus 로고
    • Tumor-host interaction: Analysis of cytokines, growth factors, and tumor-infiltrating lymphocytes in ovarian carcinomas
    • DOI 10.1016/S0046-8177(97)90131-3
    • Merogi AJ, Marrogi AJ, Ramesh R, Robinson WR, Fermin CD, Freeman SM (1997) Tumor-host interaction: analysis of cytokines, growth factors, and tumor-infiltrating lymphocytes in ovarian carcinomas. Hum Pathol 28(3):321-331 (Pubitemid 27106085)
    • (1997) Human Pathology , vol.28 , Issue.3 , pp. 321-331
    • Merogi, A.J.1    Marrogi, A.J.2    Ramesh, R.3    Robinson, W.R.4    Fermin, C.D.5    Freeman, S.M.6
  • 153
    • 84879604267 scopus 로고    scopus 로고
    • B cells and their mediators as targets for therapy in solid tumors
    • doi:10.1016/j.yexcr.2013.03.005
    • Gunderson AJ, Coussens LM (2013) B cells and their mediators as targets for therapy in solid tumors. Exp Cell Res. doi:10.1016/j.yexcr.2013.03.005
    • (2013) Exp Cell Res
    • Gunderson, A.J.1    Coussens, L.M.2
  • 154
    • 84862813718 scopus 로고    scopus 로고
    • B lymphocytes in cancer immunology
    • Medin J, Fowler DH (eds) Humana Press, New York, doi:10.1007/978-1-60761- 980-2-2
    • Spaner DE, Bahlo A (2011) B lymphocytes in cancer immunology. In: Medin J, Fowler DH (eds) Experimental and applied immunotherapy, vol XVIII. Humana Press, New York, pp 37-57. doi:10.1007/978-1-60761-980-2-2
    • (2011) Experimental and Applied Immunotherapy , vol.18 , pp. 37-57
    • Spaner, D.E.1    Bahlo, A.2
  • 155
  • 156
    • 4143138507 scopus 로고    scopus 로고
    • Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma
    • DOI 10.1093/annonc/mdh280
    • Aklilu M, Stadler WM, Markiewicz M, Vogelzang NJ, Mahowald M, Johnson M, Gajewski TF (2004) Depletion of normal B cells with rituximab as an adjunct to IL-2 therapy for renal cell carcinoma and melanoma. Ann Oncol 15(7):1109-1114. doi:10.1093/annonc/mdh280 (Pubitemid 39099116)
    • (2004) Annals of Oncology , vol.15 , Issue.7 , pp. 1109-1114
    • Aklilu, M.1    Stadler, W.M.2    Markiewicz, M.3    Vogelzang, N.J.4    Mahowald, M.5    Johnson, M.6    Gajewski, T.F.7
  • 157
    • 84886944553 scopus 로고    scopus 로고
    • Cancer immunotherapy with exosomes requires B-cell activation
    • doi:10.4161/onci.24533
    • Naslund TI, Gehrmann U, Gabrielsson S (2013) Cancer immunotherapy with exosomes requires B-cell activation. Oncoimmunology 2(6):e24533. doi:10.4161/onci.24533
    • (2013) Oncoimmunology , vol.2 , Issue.6
    • Naslund, T.I.1    Gehrmann, U.2    Gabrielsson, S.3
  • 158
    • 84874903268 scopus 로고    scopus 로고
    • Dendritic cell-derived exosomes need to activate both T and B cells to induce antitumor immunity
    • doi:10.4049/jimmunol.1203082
    • Naslund TI, Gehrmann U, Qazi KR, Karlsson MC, Gabrielsson S (2013) Dendritic cell-derived exosomes need to activate both T and B cells to induce antitumor immunity. J Immunol 190(6):2712-2719. doi:10.4049/jimmunol.1203082
    • (2013) J Immunol , vol.190 , Issue.6 , pp. 2712-2719
    • Naslund, T.I.1    Gehrmann, U.2    Qazi, K.R.3    Karlsson, M.C.4    Gabrielsson, S.5
  • 159
    • 84863890977 scopus 로고    scopus 로고
    • Design of CD40 agonists and their use in growing B cells for cancer immunotherapy
    • doi:10.3109/08830185.2012.703272
    • Kornbluth RS, Stempniak M, Stone GW (2012) Design of CD40 agonists and their use in growing B cells for cancer immunotherapy. Int Rev Immunol 31(4):279-288. doi:10.3109/08830185.2012.703272
    • (2012) Int Rev Immunol , vol.31 , Issue.4 , pp. 279-288
    • Kornbluth, R.S.1    Stempniak, M.2    Stone, G.W.3
  • 160
    • 79951942585 scopus 로고    scopus 로고
    • CD40-activated B cells contribute to mesothelioma tumor regression
    • doi:10.1038/icb.2010.88
    • Jackaman C, Cornwall S, Graham PT, Nelson DJ (2011) CD40-activated B cells contribute to mesothelioma tumor regression. Immunol Cell Biol 89(2):255-267. doi:10.1038/icb.2010.88
    • (2011) Immunol Cell Biol , vol.89 , Issue.2 , pp. 255-267
    • Jackaman, C.1    Cornwall, S.2    Graham, P.T.3    Nelson, D.J.4
  • 161
    • 33750822209 scopus 로고    scopus 로고
    • Proliferating Endothelial Cells and Leukocyte Infiltration as Prognostic Markers in Colorectal Cancer
    • DOI 10.1016/j.cgh.2006.08.005, PII S154235650600797X
    • Baeten CI, Castermans K, Hillen HF, Griffioen AW (2006) Proliferating endothelial cells and leukocyte infiltration as prognostic markers in colorectal cancer. Clin Gastroenterol Hepatol 4(11):1351-1357. doi:10.1016/j.cgh.2006.08. 005 (Pubitemid 44716741)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.11 , pp. 1351-1357
    • Baeten, C.I.M.1    Castermans, K.2    Hillen, H.F.P.3    Griffioen, A.W.4
  • 162
    • 84880588612 scopus 로고    scopus 로고
    • CD33(+)/p-STAT1(+) double-positive cell as a prognostic factor for stage IIIa gastric cancer
    • doi:10.1007/s12032-012-0442-2
    • Dong J, Li J, Liu SM, Feng XY, Chen S, Chen YB, Zhang XS (2013) CD33(+)/p-STAT1(+) double-positive cell as a prognostic factor for stage IIIa gastric cancer. Med Oncol 30(1):442. doi:10.1007/s12032-012-0442-2
    • (2013) Med Oncol , vol.30 , Issue.1 , pp. 442
    • Dong, J.1    Li, J.2    Liu, S.M.3    Feng, X.Y.4    Chen, S.5    Chen, Y.B.6    Zhang, X.S.7
  • 164
    • 55949118778 scopus 로고    scopus 로고
    • Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer
    • doi:10.1038/sj.bjc.6604738
    • Lee HE, Chae SW, Lee YJ, Kim MA, Lee HS, Lee BL, Kim WH (2008) Prognostic implications of type and density of tumour-infiltrating lymphocytes in gastric cancer. Br J Cancer 99(10):1704-1711. doi:10.1038/sj.bjc.6604738
    • (2008) Br J Cancer , vol.99 , Issue.10 , pp. 1704-1711
    • Lee, H.E.1    Chae, S.W.2    Lee, Y.J.3    Kim, M.A.4    Lee, H.S.5    Lee, B.L.6    Kim, W.H.7
  • 165
    • 84883174371 scopus 로고    scopus 로고
    • Expression pattern of tumour-associated antigens in hepatocellular carcinoma: Association with immune infiltration and disease progression
    • doi:10.1038/bjc.2013.390
    • Liang J, Ding T, Guo ZW, Yu XJ, Hu YZ, Zheng L, Xu J (2013) Expression pattern of tumour-associated antigens in hepatocellular carcinoma: association with immune infiltration and disease progression. Br J Cancer 109(4):1031-1039. doi:10.1038/bjc.2013.390
    • (2013) Br J Cancer , vol.109 , Issue.4 , pp. 1031-1039
    • Liang, J.1    Ding, T.2    Guo, Z.W.3    Yu, X.J.4    Hu, Y.Z.5    Zheng, L.6    Xu, J.7
  • 167
    • 70349881470 scopus 로고    scopus 로고
    • Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+ B-cells in metastatic lymph nodes are associated with favourable outcome in patients with oro- and hypopharyngeal carcinoma
    • doi:10.1186/1471-2407-9-292
    • Pretscher D, Distel LV, Grabenbauer GG, Wittlinger M, Buettner M, Niedobitek G (2009) Distribution of immune cells in head and neck cancer: CD8+ T-cells and CD20+ B-cells in metastatic lymph nodes are associated with favourable outcome in patients with oro- and hypopharyngeal carcinoma. BMC Cancer 9:292. doi:10.1186/1471-2407-9-292
    • (2009) BMC Cancer , vol.9 , pp. 292
    • Pretscher, D.1    Distel, L.V.2    Grabenbauer, G.G.3    Wittlinger, M.4    Buettner, M.5    Niedobitek, G.6
  • 168
    • 70349160375 scopus 로고    scopus 로고
    • Tumour infiltrating lymphocytes in squamous cell carcinoma of the oro- and hypopharynx: Prognostic impact may depend on type of treatment and stage of disease
    • doi:10.1016/j.oraloncology.2009.05.640
    • Distel LV, Fickenscher R, Dietel K, Hung A, Iro H, Zenk J, Nkenke E, Buttner M, Niedobitek G, Grabenbauer GG (2009) Tumour infiltrating lymphocytes in squamous cell carcinoma of the oro- and hypopharynx: prognostic impact may depend on type of treatment and stage of disease. Oral Oncol 45(10):e167-e174. doi:10.1016/j.oraloncology.2009.05.640
    • (2009) Oral Oncol , vol.45 , Issue.10
    • Distel, L.V.1    Fickenscher, R.2    Dietel, K.3    Hung, A.4    Iro, H.5    Zenk, J.6    Nkenke, E.7    Buttner, M.8    Niedobitek, G.9    Grabenbauer, G.G.10
  • 169
    • 0029806075 scopus 로고    scopus 로고
    • MHC class I antigens and tumour-infiltrating leucocytes in laryngeal cancer: Long-term follow-up
    • Esteban F, Redondo M, Delgado M, Garrido F, Ruiz-Cabello F (1996) MHC class I antigens and tumour-infiltrating leucocytes in laryngeal cancer: long-term follow-up. Br J Cancer 74(11):1801-1804 (Pubitemid 26401902)
    • (1996) British Journal of Cancer , vol.74 , Issue.11 , pp. 1801-1804
    • Esteban, F.1    Redondo, M.2    Delgado, M.3    Garrido, F.4    Ruiz-Cabello, F.5
  • 171
    • 52649163840 scopus 로고    scopus 로고
    • Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer
    • doi:10.1158/1078-0432.CCR-08-0133
    • Al-Shibli KI, Donnem T, Al-Saad S, Persson M, Bremnes RM, Busund LT (2008) Prognostic effect of epithelial and stromal lymphocyte infiltration in non-small cell lung cancer. Clin Cancer Res 14(16):5220-5227. doi:10.1158/1078-0432.CCR-08-0133
    • (2008) Clin Cancer Res , vol.14 , Issue.16 , pp. 5220-5227
    • Al-Shibli, K.I.1    Donnem, T.2    Al-Saad, S.3    Persson, M.4    Bremnes, R.M.5    Busund, L.T.6
  • 172
    • 77951095411 scopus 로고    scopus 로고
    • The prognostic value of intraepithelial and stromal CD3-, CD117- and CD138-positive cells in non-small cell lung carcinoma
    • doi:10.1111/j.1600-0463.2010.02609.x
    • Al-Shibli K, Al-Saad S, Andersen S, Donnem T, Bremnes RM, Busund LT (2010) The prognostic value of intraepithelial and stromal CD3-, CD117- and CD138-positive cells in non-small cell lung carcinoma. APMIS 118(5):371-382. doi:10.1111/j.1600-0463.2010.02609.x
    • (2010) APMIS , vol.118 , Issue.5 , pp. 371-382
    • Al-Shibli, K.1    Al-Saad, S.2    Andersen, S.3    Donnem, T.4    Bremnes, R.M.5    Busund, L.T.6
  • 175
    • 70350657101 scopus 로고    scopus 로고
    • Intraepithelial CD8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: Relevance of clonal selection of T lymphocytes
    • doi:10.1038/sj.bjc.6605274
    • Stumpf M, Hasenburg A, Riener MO, Jutting U, Wang C, Shen Y, Orlowska-Volk M, Fisch P, Wang Z, Gitsch G, Werner M, Lassmann S (2009) Intraepithelial CD8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: relevance of clonal selection of T lymphocytes. Br J Cancer 101(9):1513-1521. doi:10.1038/sj.bjc.6605274
    • (2009) Br J Cancer , vol.101 , Issue.9 , pp. 1513-1521
    • Stumpf, M.1    Hasenburg, A.2    Riener, M.O.3    Jutting, U.4    Wang, C.5    Shen, Y.6    Orlowska-Volk, M.7    Fisch, P.8    Wang, Z.9    Gitsch, G.10    Werner, M.11    Lassmann, S.12
  • 177
    • 37349118306 scopus 로고    scopus 로고
    • A comparative study of the cellular immune response in patients with stage IB cervical squamous cell carcinoma. Low numbers of several immune cell subtypes are strongly associated with relapse of disease within 5 years
    • DOI 10.1016/j.ygyno.2007.08.089, PII S0090825807007123
    • Nedergaard BS, Ladekarl M, Nyengaard JR, Nielsen K (2008) A comparative study of the cellular immune response in patients with stage IB cervical squamous cell carcinoma. Low numbers of several immune cell subtypes are strongly associated with relapse of disease within 5 years. Gynecol Oncol 108(1):106-111. doi:10.1016/j.ygyno.2007.08.089 (Pubitemid 350299430)
    • (2008) Gynecologic Oncology , vol.108 , Issue.1 , pp. 106-111
    • Nedergaard, B.S.1    Ladekarl, M.2    Nyengaard, J.R.3    Nielsen, K.4
  • 178
    • 28444496629 scopus 로고    scopus 로고
    • Tumour-infiltrating lymphocytes: A prognostic factor of psa-free survival in patients with local prostate carcinoma treated by radical prostatectomy
    • Karja V, Aaltomaa S, Lipponen P, Isotalo T, Talja M, Mokka R (2005) Tumour-infiltrating lymphocytes: a prognostic factor of PSA-free survival in patients with local prostate carcinoma treated by radical prostatectomy. Anticancer Res 25(6C):4435-4438 (Pubitemid 41729492)
    • (2005) Anticancer Research , vol.25 , Issue.6 C , pp. 4435-4438
    • Karja, V.1    Aaltomaa, S.2    Lipponen, P.3    Isotalo, T.4    Talja, M.5    Mokka, R.6
  • 179
    • 84886943894 scopus 로고    scopus 로고
    • High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator
    • doi:10.4161/onci.1.1.17825
    • Sorbye SW, Kilvaer T, Valkov A, Donnem T, Smeland E, Al-Shibli K, Bremnes RM, Busund LT (2012) High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator. Oncoimmunology 1(1):75-77. doi:10.4161/onci.1.1.17825
    • (2012) Oncoimmunology , vol.1 , Issue.1 , pp. 75-77
    • Sorbye, S.W.1    Kilvaer, T.2    Valkov, A.3    Donnem, T.4    Smeland, E.5    Al-Shibli, K.6    Bremnes, R.M.7    Busund, L.T.8


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