The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes

Journal of Biological Chemistry

Volumn 282, Issue 7, 2007, Pages 4850-4858

  Boswell, Sarah A ^a   Ongusaha, Pat P ^a   Nghiem, Paul ^b   Lee, Sam W ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYTOSKELETON; KERATINOCYTES; PHOTODAMAGE;

CELL DEATH; CONFORMATIONS; DNA; GENE ENCODING; PHOTODEGRADATION; RNA;

ENZYME KINETICS;

CYCLIN D1; CYCLOOXYGENASE 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; RHOE GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MEMBRANE PROTEIN; P21 ACTIVATED KINASE; PROTEIN SERINE THREONINE KINASE; PTGS2 PROTEIN, HUMAN; RHO-ASSOCIATED KINASE; RND3 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADULT; APOPTOSIS; ARTICLE; CELL COUNT; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; EPIDERMIS; HUMAN; HUMAN CELL; KERATINOCYTE; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN TARGETING; RADIATION EXPOSURE; RADIATION PROTECTION; RADIATION RESPONSE; SKIN; TRANSGENIC MOUSE; ULTRAVIOLET B RADIATION; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MOUSE; ULTRAVIOLET RADIATION;

APSEUDES; MUS MUSCULUS;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CYCLIN D1; CYCLOOXYGENASE 2; DNA DAMAGE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; MEMBRANE PROTEINS; MICE; PROTEIN-SERINE-THREONINE KINASES; RHO GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 33947499358     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610532200     Document Type: Article

References (74)

1. Riento, K., Villalonga, P., Garg, R., and Ridley, A. (2005) Biochem. Soc. Trans. 33, 649-651
2. Ridley, A. J. (2004) Breast Cancer Res. Treat. 84, 13-19
3. Jaffe, A. B., and Hall, A. (2005) Annu. Rev. Cell Dev. Biol. 21, 247-269
4. Etienne-Manneville, S., and Hall, A. (2002) Nature 420, 629-635
5. Moon, S. Y., and Zheng, Y. (2003) Trends Cell Biol. 13, 13-22
6. Chardin, P. (2003) Curr. Biol. 13, R702-704
7. Coleman, M. L., Marshall, C. J., and Olson, M. F. (2004) Nat. Rev. Mol. Cell. Biol. 5, 355-366
8. Foster, R., Hu, K. Q., Lu, Y., Nolan, K. M., Thissen, J., and Settleman, J. (1996) Mol. Cell. Biol. 16, 2689-2699
9. Guasch, R. M., Scambler, P., Jones, G. E., and Ridley, A. J. (1998) Mol. Cell. Biol. 18, 4761-4771
10. Riento, K., Guasch, R. M., Garg, R., Jin, B., and Ridley, A. J. (2003) Mol. Cell. Biol. 23, 4219-4229
11. Villalonga, P., Guasch, R. M., Riento, K., and Ridley, A. J. (2004) Mol. Cell. Biol. 24, 7829-7840
12. Ongusaha, P. P., Kim, H.-G., Boswell, S. A., Ridley, A. J., Der, C. J., Dotto, G. P., Kim, Y.-B., Aaronson, S. A., and Lee, S. W. (2006) Curr. Biol. 16, 2466-2472
13. Fuchs, E. (1990) J. Cell Biol. 111, 2807-2814
14. Ziegler, A., Jonason, A. S., Leffell, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jacks, T., and Brash, D. E. (1994) Nature 372, 773-776
15. Kulms, D., and Schwarz, T. (2002) Skin Pharmacol. Appl. Skin Physiol. 15, 342-347
16. Kulms, D., Zeise, E., Poppelmann, B., and Schwarz, T. (2002) Oncogene 21, 5844-5851
17. Adachi, M., Gazel, A., Pintucci, G., Shuck, A., Shifteh, S., Ginsburg, D., Rao, L. S., Kaneko, T., Freedberg, I. M., Tamaki, K., and Blumenberg, M. (2003) DNA Cell Biol. 22, 665-677
18. Chaturvedi, V., Sitailo, L. A., Qin, J. Z., Bodner, B., Denning, M. F., Curry, J., Zhang, W., Brash, D., and Nickoloff, B. J. (2005) Oncogene 24, 5299-5312
19. Bode, A. M., and Dong, Z. (2003) Sci. STKE 2003, RE2
20. Kitano, Y., and Okada, N. (1983) Br. J. Dermatol. 108, 555-560
21. Normand, J., and Karasek, M. A. (1995) In Vitro Cell. Dev. Biol. Anim. 31, 447-455
22. Solomon, D. E. (2002) Int. J. Exp. Pathol. 83, 209-216
23. Lehman, T. A., Modali, R., Boukamp, P., Stanek, J., Bennett, W. P., Welsh, J. A., Metcalf, R. A., Stampfer, M. R., Fusenig, N., Rogan, E. M., and Harris, C. C. (1993) Carcinogenesis 14, 833-839
24. Henseleit, U., Zhang, J., Wanner, R., Haase, I., Kolde, G., and Rosenbach, T. (1997) J. Investig. Dermatol. 109, 722-727
25. Bowen, A. R., Hanks, A. N., Allen, S. M., Alexander, A., Diedrich, M. J., and Grossman, D. (2003) J. Investig. Dermatol. 120, 48-55
26. Chouinard, N., Valerie, K., Rouabhia, M., and Huot, J. (2002) Biochem. J. 365, 133-145
27. Reagan-Shaw, S., Breur, J., and Ahmad, N. (2006) Mol. Cancer Ther. 5, 418-429
28. Loignon, M., Fetni, R., Gordon, A. J., and Drobetsky, E. A. (1997) Cancer Res. 57, 3390-3394
29. Liu, M., Wikonkal, N. M., and Brash, D. E. (1999) J. Investig. Dermatol. 113, 283-284
30. Kim, H. J., Lim, S. C., Kim, S. H., and Kim, T. Y. (2003) Mol. Cells 16, 331-337
31. Aliouat-Denis, C. M., Dendouga, N., Van den Wyngaert, I., Goehlmann, H., Steller, U., van de Weyer, I., Van Slycken, N., Andries, L., Kass, S., Luyten, W., Janicot, M., and Vialard, J. E. (2005) Mol. Cancer Res. 3, 627-634
32. Decraene, D., Smaers, K., Maes, D., Matsui, M., Declercq, L., and Garmyn, M. (2005) J. Investig. Dermatol. 125, 1026-1031
33. Kapoor, M., Hamm, R., Yan, W., Taya, Y., and Lozano, G. (2000) Oncogene 19, 358-364
34. She, Q. B., Chen, N., and Dong, Z. (2000) J. Biol. Chem. 275, 20444-20449
35. She, Q. B., Ma, W. Y., and Dong, Z. (2002) Oncogene 21, 1580-1589
36. Datto, M. B., Li, Y., Panus, J. F., Howe, D. J., Xiong, Y., and Wang, X. F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5545-5549
37. Bartek, J., Iggo, R., Gannon, J., and Lane, D. P. (1990) Oncogene 5, 893-899
38. Iggo, R., Gatter, K., Bartek, J., Lane, D., and Harris, A. L. (1990) Lancet 335, 675-679
39. Dowell, S. P., Wilson, P. O., Derias, N. W., Lane, D. P., and Hall, P. A. (1994) Cancer Res. 54, 2914-2918
40. Soussi, T. (2000) Ann. N. Y. Acad. Sci. 910, 121-139
41. Chaturvedi, V., Qin, J. Z., Denning, M. F., Choubey, D., Diaz, M. O., and Nickoloff, B. J. (2001) J. Dermatol. Sci. 26, 67-78
42. Dhanalakshmi, S., Mallikarjuna, G. U., Singh, R. P., and Agarwal, R. (2004) Carcinogenesis 25, 99-106
43. Riento, K., Totty, N., Villalonga, P., Garg, R., Guasch, R., and Ridley, A. J. (2005) EMBO J. 24, 1170-1180
44. Kielbassa, C., Roza, L., and Epe, B. (1997) Carcinogenesis 18, 811-816
45. de Gruijl, F. R. (2000) Methods Enzymol. 319, 359-366
46. Kuluncsics, Z., Perdiz, D., Brulay, E., Muel, B., and Sage, E. (1999) J. Photochem. Photobiol. B Biol. 49, 71-80
47. Tornaletti, S., Rozek, D., and Pfeifer, G. P. (1993) Oncogene 8, 2051-2057
48. Wikonkal, N. M., and Brash, D. E. (1999) J. Investig. Dermatol. Symp. Proc. 4, 6-10
49. Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J., and Greenberg, M. E. (1995) Science 270, 1326-1331
50. Christmann, M., Tomicic, M. T., Aasland, D., and Kaina, B. (2006) Carcinogenesis 28, 183-190
51. Shimizu, H., Banno, Y., Sumi, N., Naganawa, T., Kitajima, Y., and Nozawa, Y. (1999) J. Investig. Dermatol. 112, 769-774
52. Assefa, Z., Vantieghem, A., Garmyn, M., Declercq, W., Vandenabeele, P., Vandenheede, J. R., Bouillon, R., Merlevede, W., and Agostinis, P. (2000) J. Biol. Chem. 275, 21416-21421
53. Assefa, Z., Garmyn, M., Bouillon, R., Merlevede, W., Vandenheede, J. R., and Agostinis, P. (1997) J. Investig. Dermatol. 108, 886-891
54. Seo, M., Cho, C. H., Lee, Y. I., Shin, E. Y., Park, D., Bae, C. D., Lee, J. W., Lee, E. S., and Juhnn, Y. S. (2004) J. Biol. Chem. 279, 17366-17375
55. Chen, W., Tang, Q., Gonzales, M. S., and Bowden, G. T. (2001) Oncogene 20, 3921-3926
56. Bachelor, M. A., Silvers, A. L., and Bowden, G. T. (2002) Oncogene 21, 7092-7099
57. Tripp, C. S., Blomme, E. A., Chinn, K. S., Hardy, M. M., LaCelle, P., and Pentland, A. P. (2003) J. Investig. Dermatol. 121, 853-861
58. Iordanov, M. S., Choi, R. J., Ryabinina, O. P., Dinh, T. H., Bright, R. K., and Magun, B. E. (2002) Mol. Cell. Biol. 22, 5380-5394
59. Sauter, E. R., Nesbit, M., Litwin, S., Klein-Szanto, A. J., Cheffetz, S., and Herlyn, M. (1999) Cancer Res. 59, 4876-4881
60. Zhou, P., Jiang, W., Zhang, Y. J., Kahn, S. M., Schieren, I., Santella, R. M., and Weinstein, I. B. (1995) Oncogene 11, 571-580
61. Driscoll, B.,Wu,L., Buckley, S., Hall, F. L., Anderson, K. D., and Warburton, D. (1997) Am. J. Physiol. 273, L941-L949
62. Albanese, C., D'Amico, M., Reutens, A. T., Fu, M., Watanabe, G., Lee, R. J., Kitsis, R. N., Henglein, B., Avantaggiati, M., Somasundaram, K., Thimmapaya, B., and Pestell, R. G. (1999) J. Biol. Chem. 274, 34186-34195
63. Rosenberg, C. L., Motokura, T., Kronenberg, H. M., and Arnold, A. (1993) Oncogene 8, 519-521
64. Wang, T. C., Cardiff, R. D., Zukerberg, L., Lees, E., Arnold, A., and Schmidt, E. V. (1994) Nature 369, 669-671
65. Bagrodia, S., Derijard, B., Davis, R. J., and Cerione, R. A. (1995) J. Biol. Chem. 270, 27995-27998
66. Coso, O. A., Chiariello, M., Yu, J. C., Teramoto, H., Crespo, P., Xu, N., Miki, T., and Gutkind, J. S. (1995) Cell 81, 1137-1146
67. Olson, M. F., Ashworth, A., and Hall, A. (1995) Science 269, 1270 -1272
68. Welsh, C. F., Roovers, K., Villanueva, J., Liu, Y., Schwartz, M. A., and Assoian, R. K. (2001) Nat. Cell Biol. 3, 950-957
69. Roovers, K., and Assoian, R. K. (2003) Mol. Cell. Biol. 23, 4283-4294
70. Liberto, M., Cobrinik, D., and Minden, A. (2002) Oncogene 21, 1590 -1599
71. Minden, A., Lin, A., Claret, F. X., Abo, A., and Karin, M. (1995) Cell 81, 1147-1157
72. Lopez-Ilasaca, M. (1998) Biochem. Pharmacol. 56, 269-277
73. Welsh, C. F. (2004) Breast Cancer Res. Treat. 84, 33-42
74. Wennerberg, K., Forget, M. A., Ellerbroek, S. M., Arthur, W. T., Burridge, K., Settleman, J., Der, C. J., and Hansen, S. H. (2003) Curr. Biol. 13, 1106-1115