Inhibition of palmitate-induced GADD34 expression augments apoptosis in mouse insulinoma cells (MIN6)

Cell Biochemistry and Function

Volumn 32, Issue 5, 2014, Pages 445-452

  Fransson, Liselotte ^a   Sjöholm, Åke ^b,c   Ortsäter, Henrik ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Sodertalje Hospital   (Sweden)

^c UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Beta cell; Diabetes; Endoplasmic reticulum stress; GADD34; Islet; Palmitate; Salubrinal

Indexed keywords

CASPASE 3; DNA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; INITIATION FACTOR 2ALPHA; INSULIN; PALMITIC ACID; PROTEIN SERINE THREONINE KINASE; RNA ACTIVATED PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM LOCALIZED EIF2ALPHA KINASE; SALUBRINAL; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, MOUSE; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; PALMITIC ACID DERIVATIVE; PERK KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, MOUSE; PROTEIN KINASE R;

ANIMAL CELL; APOPTOSIS; ARTICLE; CYTOTOXICITY; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN TISSUE; MALE; MIN6 CELL LINE; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INSULINOMA; METABOLISM; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; TOXICITY; TUMOR CELL LINE;

EUKARYOTA;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; DNA FRAGMENTATION; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION, NEOPLASTIC; INSULINOMA; MICE; PALMITATES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 84903755994     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3036     Document Type: Article

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