A cellular system that degrades misfolded proteins and protects against neurodegeneration

Molecular Cell

Volumn 55, Issue 1, 2014, Pages 15-30

  Guo, Lili ^a   Giasson, Benoit I ^b,c   Glavis Bloom, Alex ^a   Brewer, Michael D ^a   Shorter, James ^b   Gitler, Aaron D ^b,d   Yang, Xiaolu ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYGLUTAMINE; PROMYELOCYTIC LEUKEMIA PROTEIN; SUMO PROTEIN; UBIQUITIN LIGASE RNF4; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL NUCLEUS; CONJUGATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR RECOGNITION; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN MISFOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SPINOCEREBELLAR DEGENERATION; SUMOYLATION; UBIQUITINATION;

MAMMALIA;

ANIMALS; HUMANS; MICE; MODELS, BIOLOGICAL; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; PROTEOLYSIS; SPINOCEREBELLAR ATAXIAS; SUMOYLATION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; UBIQUITINATION;

EID: 84903691140     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.04.030     Document Type: Article

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