Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27

Journal of Leukocyte Biology

Volumn 96, Issue 1, 2014, Pages 123-131

  Bosmann, Markus ^a   Strobl, Birgit ^b   Kichler, Nadia ^b   Rigler, Doris ^b   Grailer, Jamison J ^c   Pache, Florence ^c   Murray, Peter J ^d   Müller, Mathias ^b   Ward, Peter A ^c  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Inflammation; Interferon; Lipopolysaccharide; Macrophages; Shock

Indexed keywords

BETA INTERFERON; FOCAL ADHESION KINASE 1; INTERLEUKIN 10; INTERLEUKIN 27; INTERLEUKIN 4; MYELOID DIFFERENTIATION FACTOR 88; STAT1 PROTEIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR T BET;

ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RNA ISOLATION; SEPSIS; SEPTIC SHOCK; SIGNAL TRANSDUCTION;

INFLAMMATION; INTERFERON; LIPOPOLYSACCHARIDE; MACROPHAGES; SHOCK;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; INTERFERON-BETA; INTERLEUKINS; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TYK2 KINASE;

EID: 84903532098     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3A1013-541R     Document Type: Article

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