Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-γ production and the induction of Th1 cell differentiation

Blood

Volumn 110, Issue 2, 2007, Pages 553-560

  Tokumasa, Naoki ^a   Suto, Akira ^a   Kagami, Shin Ichiro ^a   Furuta, Shunsuke ^a   Hirose, Koichi ^a   Watanabe, Norihiko ^a   Saito, Yasushi ^a   Shimoda, Kazuya ^b   Iwamoto, Itsuo ^c   Nakajima, Hiroshi ^a,d  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c ASAHI GENERAL HOSPITAL   (Japan)

^d CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 23; JANUS KINASE; PROTEIN TYK2; STAT4 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL;

EID: 34547138698     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-11-059246     Document Type: Article

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