Jak2 and Tyk2 are necessary for lineage-specific differentiation, but not for the maintenance of self-renewal of mouse embryonic stem cells

Biochemical and Biophysical Research Communications

Volumn 351, Issue 3, 2006, Pages 682-688

  Chung, Bo Mee ^a   Kang, Ho Chul ^a   Han, Su Youne ^a   Heo, Hyen Seok ^a   Lee, Jong Joo ^a   Jeon, Jinseon ^a   Lim, Ji Young ^a   Shin, Incheol ^a   Hong, Seung Hwan ^b   Cho, Yoon Shin ^a   Kim, Chul Geun ^a  

^a Hanyang University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Differentiation; Jak2; LIF induced Jak1 STAT3 signaling pathway; Lineage specification; mESCs; Microarray; RNAi; Self renewal; Tyk2

Indexed keywords

JANUS KINASE 2; LITHIUM CHLORIDE; STAT3 PROTEIN; WNT PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL RENEWAL; CELL TYPE; CONTROLLED STUDY; ECTODERM; EMBRYONIC STEM CELL; ENDODERM; MESODERM; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TISSUE SPECIFICITY; WILD TYPE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; EMBRYONIC STEM CELLS; JANUS KINASE 2; MICE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TYK2 KINASE;

EID: 33751252282     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.10.081     Document Type: Article

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