31P Magnetic resonance spectroscopic imaging with polarisation transfer of phosphomono- and diesters at 3 T in the human brain: Relation with age and spatial differences

NMR in Biomedicine

Volumn 23, Issue 8, 2010, Pages 968-976

  Wijnen, J P ^a   Scheenen, T W J ^a,b   Klomp, D W J ^a   Heerschap, A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

3 T; 31P MRSI; Age dependence; Brain; Phosphodiesters; Phosphomonoesters; Spatial differences; Tumour

Indexed keywords

3 T; 31P MRSI; AGE DEPENDENCE; PHOSPHODIESTERS; PHOSPHOMONOESTERS; SPATIAL DIFFERENCES; TUMOUR;

BRAIN; ESTERS; MAGNETIC RESONANCE; MAGNETIC RESONANCE SPECTROSCOPY; METABOLISM; PHOSPHOLIPIDS; PHOSPHORYLATION; POLARIZATION; POLLUTION DETECTION; SIGNAL TO NOISE RATIO; TUMORS;

SIGNAL DETECTION;

GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; ESTER; PHOSPHATIDYLETHANOLAMINE; PHOSPHORUS;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; FEASIBILITY STUDY; FEMALE; GRAY MATTER; HUMAN; IMAGING SYSTEM; MALE; NORMAL HUMAN; OCCIPITAL LOBE; PARIETAL LOBE; PHOSPHOLIPID METABOLISM; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SELECTIVE REFOCUSED INSENSITIVE NUCLEI ENHANCED POLARIZATION TRANSFER; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; THREE DIMENSIONAL IMAGING; AGING; BRAIN; BRAIN TUMOR; CHEMISTRY; HISTOLOGY; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY;

ADOLESCENT; ADULT; AGED; AGING; BRAIN; BRAIN NEOPLASMS; ESTERS; GLYCERYLPHOSPHORYLCHOLINE; HUMANS; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; PHOSPHATIDYLETHANOLAMINES; PHOSPHORUS ISOTOPES; YOUNG ADULT;

EID: 78651519725     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1523     Document Type: Article

References (38)

1. Rango M, Bonifati C, Bresolin N. Parkinson's disease and brain mitochondrial dysfunction: a functional phosphorus magnetic resonance spectroscopy study. J Cerebr Blood Flow Metab. 2006; 26(2): 283-290.
2. Pettegrew JW, Panchalingam K, Klunk WE, McClure RJ, Muenz LR. Alterations of cerebral metabolism in probable Alzheimer's disease: a preliminary study. Neurobiol Aging. 1994; 15(1): 117-132.
3. Renshaw PF, Parow AM, Hirashima F, Ke Y, Moore CM, Frederick Bde B. Fava M, Hennen J, Cohen BM. Multinuclear magnetic resonance spectroscopy studies of brain purines in major depression. Am J Psychiatry. 2001; 158(12): 2048-2055.
4. Hubesch B, Sappey-Marinier D, Roth K, Meyerhoff DJ, Matson GB, Weiner MW. P-31 MR spectroscopy of normal human brain and brain tumors. Radiology. 1990; 174(2): 401-409.
5. Negendank W. Studies of human tumors by MRS: a review. NMR Biomed. 1992; 5(5): 303-324.
6. Segebarth CM, Baleriaux DF, Arnold DL, Luyten PR, den Hollander JA. MR image-guided P-31 MR spectroscopy in the evaluation of brain tumor treatment. Radiology. 1987; 165(1): 215-219.
7. Podo F. Tumour phospholipid metabolism. NMR Biomed. 1999; 12(7): 413-439.
8. Jensen JE, Miller J, Williamson PC, Neufeld RW, Menon RS, Malla A, Manchanda R, Schaefer B, Densmore M, Drost DJ. Grey and white matter differences in brain energy metabolism in first episode schizophrenia: 31P-MRS chemical shift imaging at 4 Tesla. Psychiatry Res. 2006; 146(2): 127-135.
9. Komoroski RA, Pearce JM, Mrak RE. 31P NMR spectroscopy of phospholipid metabolites in postmortem schizophrenic brain. Magn Reson Med. 2008; 59(3): 469-474.
10. Pettegrew JW, Kopp SJ, Minshew NJ, Glonek T, Feliksik JM, Tow JP, Cohen MM. 31P nuclear magnetic resonance studies of phosphoglyceride metabolism in developing and degenerating brain: preliminary observations. J Neuropathol Exp Neurol. 1987; 46(4): 419-430.
11. Brown TR, Stoyanova R, Greenberg T, Srinivasan R, Murphy-Boesch J. NOE enhancements and T1 relaxation times of phosphorylated metabolites in human calf muscle at 1.5 Tesla. Magn Reson Med. 1995; 33(3): 417-421.
12. Luyten PR, Bruntink G, Sloff FM, Vermeulen JW, van der Heijden JI, den Hollander JA, Heerschap A. Broadband proton decoupling in human 31P NMR spectroscopy. NMR Biomed. 1989; 1(4): 177-183.
13. Overhauser AW. Polarization of nuclei in metals. Phys Rev. 1953; 92(2): 411-415.
14. Mancini L, Payne GS, Leach MO. Comparison of polarization transfer sequences for enhancement of signals in clinical 31P MRS studies. Magn Reson Med. 2003; 50(3): 578-588.
15. Gonen O, Mohebbi A, Stoyanova R, Brown TR. In vivo phosphorus polarization transfer and decoupling from protons in three-dimensional localized nuclear magnetic resonance spectroscopy of human brain. Magn Reson Med. 1997; 37(2): 301-306.
16. Klomp DW, Wijnen JP, Scheenen TW. Heerschap A. Efficient 1H to 31P polarization transfer on a clinical 3T MR system. Magn Reson Med. 2008; 60(6): 1298-1305. doi: 10.1002/mrm.21733.
17. Klomp DW, Renema WK, van der Graaf M, de Galan BE, Kentgens AP. Heerschap A. Sensitivity-enhanced 13C MR spectroscopy of the human brain at 3 Tesla. Magn Reson Med. 2006; 55(2): 271-278.
18. Naressi A, Couturier C, Devos JM, Janssen M, Mangeat C, de Beer R, Graveron-Demilly D. Java-based graphical user interface for the MRUI quantitation package. Magn Reson Mater Phys. 2001; 12(2-3): 141-152.
19. Vanhamme L, van den Boogaart A, van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson. 1997; 129(1): 35-43.
20. Jensen JE, Drost DJ, Menon RS, Williamson PC. In vivo brain (31)P-MRS: measuring the phospholipid resonances at 4 Tesla from small voxels. NMR Biomed. 2002; 15(5): 338-347.
21. Forester BP, Berlow YA, Harper DG, Jensen JE, Lange N, Froimowitz MP, Ravichandran C, Iosifescu DV, Lukas SE, Renshaw PF, Cohen BM. Age-related changes in brain energetics and phospholipid metabolism. NMR Biomed. 2010; 23(3): 242-250.
22. Buchli R, Duc CO, Martin E, Boesiger P. Assessment of absolute metabolite concentrations in human tissue by 31P MRS in vivo. Part I: Cerebrum, cerebellum, cerebral gray and white matter. Magn Reson Med. 1994; 32(4): 447-452.
23. Bluml S, Seymour KJ, Ross BD. Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain. Magn Reson Med. 1999; 42(4): 643-654.
24. Jensen JE, Al-Semaan YM, Williamson PC, Neufeld RW, Menon RS, Schaeffer B, Densmore M, Drost DJ. Region-specific changes in phospholipid metabolism in chronic, medicated schizophrenia: (31)P-MRS study at 4.0 Tesla. Br J Psychiatry. 2002; 180: 39-44.
25. Pfefferbaum A, Adalsteinsson E, Spielman D, Sullivan EV, Lim KO. In vivo spectroscopic quantification of the N-acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: effects of normal aging. Magn Reson Med. 1999; 41(2): 276-284.
26. Kok RD, van den Berg PP, van den Bergh AJ, Nijland R, Heerschap A. Maturation of the human fetal brain as observed by 1H MR spectroscopy. Magn Reson Med. 2002; 48(4): 611-616.
27. Kreis R, Ernst T, Ross BD. Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med. 1993; 30(4): 424-437.
28. Pouwels PJ, Brockmann K, Kruse B, Wilken B, Wick M, Hanefeld F, Frahm J. Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS. Pediatr Res 1999; 46(4): 474-485.
29. Angelie E, Bonmartin A, Boudraa A, Gonnaud PM, Mallet JJ, Sappey-Marinier D. Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study. Am J Neuroradiol. 2001; 22(1): 119-127.
30. Chang L, Ernst T, Poland RE, Jenden DJ. In vivo proton magnetic resonance spectroscopy of the normal aging human brain. Life Sci. 1996; 58(22): 2049-2056.
31. Maudsley AA, Domenig C, Govind V, Darkazanli A, Studholme C, Arheart K, Bloomer C. Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI). Magn Reson Med. 2008; 61(3): 548-559.
32. Pohmann R, von Kienlin M. Accurate phosphorus metabolite images of the human heart by 3D acquisition-weighted CSI. Magn Reson Med. 2001; 45(5): 817-826.
33. Pettegrew JW, Panchalingam K, Withers G, McKeag D, Strychor S. Changes in brain energy and phospholipid metabolism during development and aging in the Fischer 344 rat. J Neuropathol Exp Neurol. 1990; 49(3): 237-249.
34. Albers MJ, Krieger MD, Gonzalez-Gomez I, Gilles FH, McComb JG, Nelson MD Jr., Bluml S. Proton-decoupled 31P MRS in untreated pediatric brain tumors. Magn Reson Med. 2005; 53(1): 22-29.
35. Solivera J, Cerdan S, Pascual JM, Barrios L, Roda JM. Assessment of 31P-NMR analysis of phospholipid profiles for potential differential diagnosis of human cerebral tumors. NMR Biomed. 2009; 22(6): 663-674.
36. Herminghaus S, Pilatus U, Moller-Hartmann W, Raab P, Lanfermann H, Schlote W, Zanella FE. Increased choline levels coincide with enhanced proliferative activity of human neuroepithelial brain tumors. NMR Biomed. 2002; 15(6): 385-392. doi: 10.1002/nbm.793.
37. Kugel H, Heindel W, Ernestus RI, Bunke J. du Mesnil R. Friedmann G. Human brain tumors: spectral patterns detected with localized H-1 MR spectroscopy. Radiology. 1992; 183(3): 701-709.
38. Scheenen TW, Klomp DW, Roll SA, Futterer JJ, Barentsz JO, Heerschap A. Fast acquisition-weighted three-dimensional proton MR spectroscopic imaging of the human prostate. Magn Reson Med. 2004; 52(1): 80-88.