Metabotropic glutamate receptor 3 protects neurons from glucose-induced oxidative injury by increasing intracellular glutathione concentration

Journal of Neurochemistry

Volumn 101, Issue 2, 2007, Pages 342-354

  Berent Spillson, Alison ^a   Russell, James W ^a,b,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetic neuropathy; Glutathione; Metabotropic glutamate receptor; Oxidative stress; Schwann cell

Indexed keywords

4 AMINOPYRROLIDINE 2,4 DICARBOXYLATE; GLUCOSE; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR AGONIST; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LEVEL; CELL MEMBRANE DEPOLARIZATION; COCULTURE; CONTROLLED STUDY; DRUG MECHANISM; GLUTATHIONE METABOLISM; MITOCHONDRION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SCHWANN CELL; SPINAL GANGLION;

ANIMALS; ANTIMETABOLITES; APOPTOSIS; BUTHIONINE SULFOXIMINE; CELLS, CULTURED; COCULTURE TECHNIQUES; DIABETIC NEUROPATHIES; EXCITATORY AMINO ACID AGONISTS; GANGLIA, SPINAL; GLUCOSE; GLUTATHIONE; HYPERGLYCEMIA; INTRACELLULAR SPACE; MITOCHONDRIAL MEMBRANES; NEURONS, AFFERENT; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, METABOTROPIC GLUTAMATE; SCHWANN CELLS; UP-REGULATION;

RATTUS;

EID: 34047133306     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04373.x     Document Type: Article

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