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Volumn 141, Issue 1, 1999, Pages 104-120

Toward an in Vivo Neurochemical Profile: Quantification of 18 Metabolites in Short-Echo-Time 1H NMR Spectra of the Rat Brain

Author keywords

In vivo 1H NMR spectroscopy; LCModel; Macromolecules; Quantification; Rat brain; Short echo time

Indexed keywords

AMINO ACID;

EID: 0033226834     PISSN: 10907807     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmre.1999.1895     Document Type: Article
Times cited : (426)

References (65)
  • 2
    • 0028695478 scopus 로고
    • Clinical applications of magnetic resonance spectroscopy
    • B. D. Ross and T. Michaelis, Clinical applications of magnetic resonance spectroscopy, Magn. Reson. Q. 10, 191-247 (1994).
    • (1994) Magn. Reson. Q. , vol.10 , pp. 191-247
    • Ross, B.D.1    Michaelis, T.2
  • 5
    • 0000307298 scopus 로고    scopus 로고
    • Cerebral amino acids studied by nuclear magnetic resonance spectroscopy in vivo
    • S. R. Williams, Cerebral amino acids studied by nuclear magnetic resonance spectroscopy in vivo, Prog. NMR Spectrosc. 34, 301-326 (1999).
    • (1999) Prog. NMR Spectrosc. , vol.34 , pp. 301-326
    • Williams, S.R.1
  • 6
    • 0029014638 scopus 로고
    • The use of a priori knowledge to quantify short echo in vivo 1H MR spectra
    • J. A. Stanley, D. J. Drost, P. C. Williamson, and R. T. Thompson, The use of a priori knowledge to quantify short echo in vivo 1H MR spectra, Magn. Reson. Med. 34, 17-24 (1995).
    • (1995) Magn. Reson. Med. , vol.34 , pp. 17-24
    • Stanley, J.A.1    Drost, D.J.2    Williamson, P.C.3    Thompson, R.T.4
  • 7
    • 0029981235 scopus 로고    scopus 로고
    • Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain
    • J. H. Hwang, G. D. Graham, K. L. Behar, J. R. Alger, J. W. Prichard, and D. L. Rothman, Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain, Magn. Reson. Med. 35, 633-639 (1996).
    • (1996) Magn. Reson. Med. , vol.35 , pp. 633-639
    • Hwang, J.H.1    Graham, G.D.2    Behar, K.L.3    Alger, J.R.4    Prichard, J.W.5    Rothman, D.L.6
  • 8
    • 0031401414 scopus 로고    scopus 로고
    • Discrimination of metabolite from lipid and macromolecule resonances in cerebral infarction in humans using short echo proton spectroscopy
    • D. E. Saunders, F. A. Howe, A. van den Boogaart, J. R. Griffiths, and M. M. Brown, Discrimination of metabolite from lipid and macromolecule resonances in cerebral infarction in humans using short echo proton spectroscopy, J. Magn. Reson. Imaging 7, 1116-1121 (1997).
    • (1997) J. Magn. Reson. Imaging , vol.7 , pp. 1116-1121
    • Saunders, D.E.1    Howe, F.A.2    Van Den Boogaart, A.3    Griffiths, J.R.4    Brown, M.M.5
  • 9
    • 0030846501 scopus 로고    scopus 로고
    • Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS
    • P. J. Pouwels and J. Frahm, Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS, NMR Biomed. 10, 73-78 (1997).
    • (1997) NMR Biomed. , vol.10 , pp. 73-78
    • Pouwels, P.J.1    Frahm, J.2
  • 10
    • 0002455590 scopus 로고    scopus 로고
    • Metabolite identification in cell extracts and culture media by proton-detected 2D-H,C-NMR spectroscopy
    • W. Willker, J. Engelmann, A. Brand, and D. Leibfritz, Metabolite identification in cell extracts and culture media by proton-detected 2D-H,C-NMR spectroscopy, J. Magn. Reson. Anal. 2, 21-32 (1996).
    • (1996) J. Magn. Reson. Anal. , vol.2 , pp. 21-32
    • Willker, W.1    Engelmann, J.2    Brand, A.3    Leibfritz, D.4
  • 11
    • 0027567590 scopus 로고
    • 1H magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus
    • 1H magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus, Neurology 43, 589-594 (1993).
    • (1993) Neurology , vol.43 , pp. 589-594
    • Peeling, J.1    Sutherland, G.2
  • 13
    • 0023933981 scopus 로고
    • High-resolution proton magnetic resonance spectroscopy of rabbit brain: Regional metabolite levels and postmortem changes
    • O. A. Petroff, T. Ogino, and J. R. Alger, High-resolution proton magnetic resonance spectroscopy of rabbit brain: Regional metabolite levels and postmortem changes, J. Neurochem. 51, 163-171 (1988).
    • (1988) J. Neurochem. , vol.51 , pp. 163-171
    • Petroff, O.A.1    Ogino, T.2    Alger, J.R.3
  • 15
    • 0029082396 scopus 로고
    • On the use of two-dimensional-J NMR measurements for in vivo proton MRS: Measurement of homonuclear decoupled spectra without the need for short echo times
    • W. Dreher and D. Leibfritz, On the use of two-dimensional-J NMR measurements for in vivo proton MRS: Measurement of homonuclear decoupled spectra without the need for short echo times, Magn. Reson. Med. 34, 331-337 (1995).
    • (1995) Magn. Reson. Med. , vol.34 , pp. 331-337
    • Dreher, W.1    Leibfritz, D.2
  • 16
    • 0028108335 scopus 로고
    • Localized two-dimensional shift correlated spectroscopy in humans at 2 Tesla
    • I. M. Brereton, G. J. Galloway, S. E. Rose, and D. M. Doddrell, Localized two-dimensional shift correlated spectroscopy in humans at 2 Tesla, Magn. Reson. Med. 32, 251-257 (1994).
    • (1994) Magn. Reson. Med. , vol.32 , pp. 251-257
    • Brereton, I.M.1    Galloway, G.J.2    Rose, S.E.3    Doddrell, D.M.4
  • 18
    • 0000475729 scopus 로고
    • Analysis of NMR data using time domain fitting procedures
    • R. de Beer and D. van Ormondt, Analysis of NMR data using time domain fitting procedures, NMR Basic Princ. Prog. 26, 201-248 (1992).
    • (1992) NMR Basic Princ. Prog. , vol.26 , pp. 201-248
    • De Beer, R.1    Van Ormondt, D.2
  • 19
  • 20
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • S. W. Provencher, Estimation of metabolite concentrations from localized in vivo proton NMR spectra, Magn. Reson. Med. 30, 672-679 (1993).
    • (1993) Magn. Reson. Med. , vol.30 , pp. 672-679
    • Provencher, S.W.1
  • 21
    • 0031836558 scopus 로고    scopus 로고
    • Versatile frequency domain fitting using time domain models and prior knowledge
    • J. Slotboom, C. Boesch, and R. Kreis, Versatile frequency domain fitting using time domain models and prior knowledge, Magn. Reson. Med. 39, 899-911 (1998).
    • (1998) Magn. Reson. Med. , vol.39 , pp. 899-911
    • Slotboom, J.1    Boesch, C.2    Kreis, R.3
  • 22
    • 58149364545 scopus 로고
    • Application of principal-component analysis for NMR spectral quantitation
    • R. Stoyanova, A. C. Kuesel, and T. R. Brown, Application of principal-component analysis for NMR spectral quantitation, J. Magn. Reson. A 115, 265-269 (1995).
    • (1995) J. Magn. Reson. A , vol.115 , pp. 265-269
    • Stoyanova, R.1    Kuesel, A.C.2    Brown, T.R.3
  • 23
    • 0031756714 scopus 로고    scopus 로고
    • Automated spectral analysis III: Application to in vivo proton MR spectroscopy and spectroscopic imaging
    • B. J. Soher, K. Young, V. Govindaraju, and A. A. Maudsley, Automated spectral analysis III: Application to in vivo proton MR spectroscopy and spectroscopic imaging, Magn. Reson. Med. 40, 822-831 (1998).
    • (1998) Magn. Reson. Med. , vol.40 , pp. 822-831
    • Soher, B.J.1    Young, K.2    Govindaraju, V.3    Maudsley, A.A.4
  • 24
    • 0030093031 scopus 로고    scopus 로고
    • Application of genetic algorithms to spectral quantification
    • G. J. Metzger, M. Patel, and X. Hu, Application of genetic algorithms to spectral quantification, J. Magn. Reson. B 110, 316-320 (1996).
    • (1996) J. Magn. Reson. B , vol.110 , pp. 316-320
    • Metzger, G.J.1    Patel, M.2    Hu, X.3
  • 25
    • 0031980729 scopus 로고    scopus 로고
    • Heuristic optimization algorithms applied to the quantification of spectroscopic data
    • O. M. Weber, C. O. Duc, D. Meier, and P. Boesiger, Heuristic optimization algorithms applied to the quantification of spectroscopic data, Magn. Reson. Med. 39, 723-730 (1998).
    • (1998) Magn. Reson. Med. , vol.39 , pp. 723-730
    • Weber, O.M.1    Duc, C.O.2    Meier, D.3    Boesiger, P.4
  • 28
    • 0032012581 scopus 로고    scopus 로고
    • Localized eddy current compensation using quantitative field mapping
    • M. Terpstra, P. M. Andersen, and R. Gruetter, Localized eddy current compensation using quantitative field mapping, J. Magn. Reson. 131, 139-143 (1998).
    • (1998) J. Magn. Reson. , vol.131 , pp. 139-143
    • Terpstra, M.1    Andersen, P.M.2    Gruetter, R.3
  • 29
    • 0031083483 scopus 로고    scopus 로고
    • A half-volume coil for efficient proton decoupling in humans at 4 Tesla
    • G. Adriany and R. Gruetter, A half-volume coil for efficient proton decoupling in humans at 4 Tesla, J. Magn. Reson. 125, 178-184 (1997).
    • (1997) J. Magn. Reson. , vol.125 , pp. 178-184
    • Adriany, G.1    Gruetter, R.2
  • 30
    • 0000842145 scopus 로고    scopus 로고
    • Improved performance of frequency-swept pulses using offset-independent adiabaticity
    • A. Tannus and M. Garwood, Improved performance of frequency-swept pulses using offset-independent adiabaticity, J. Magn. Reson. A 120, 133-137 (1996).
    • (1996) J. Magn. Reson. A , vol.120 , pp. 133-137
    • Tannus, A.1    Garwood, M.2
  • 31
    • 0027200329 scopus 로고
    • Automatic, localized in vivo adjustment of all first- and second-order shim coils
    • R. Gruetter, Automatic, localized in vivo adjustment of all first- and second-order shim coils, Magn. Reson. Med. 29, 804-811 (1993).
    • (1993) Magn. Reson. Med. , vol.29 , pp. 804-811
    • Gruetter, R.1
  • 34
    • 0001461139 scopus 로고
    • Cerebral amino acid pools
    • (A. Lajtha, Ed.), 2nd ed., Plenum Press, New York
    • T. L. Perry, Cerebral amino acid pools, in "Handbook of Neurochemistry" (A. Lajtha, Ed.), 2nd ed., Vol. 1, pp. 151-180, Plenum Press, New York (1982).
    • (1982) Handbook of Neurochemistry , vol.1 , pp. 151-180
    • Perry, T.L.1
  • 35
    • 0002517766 scopus 로고
    • Intermediary metabolism
    • (G. J. Siegel, Ed.), Raven, New York
    • D. D. Clarke, A. L. Lajtha, and H. S. Maher, Intermediary metabolism, in "Basic Neurochemistry" (G. J. Siegel, Ed.), pp. 541-564, Raven, New York (1989).
    • (1989) Basic Neurochemistry , pp. 541-564
    • Clarke, D.D.1    Lajtha, A.L.2    Maher, H.S.3
  • 36
    • 0015541653 scopus 로고
    • Freeze-blowing: A new technique for the study of brain in vivo
    • R. L. Veech, R. L. Harris, D. Veloso, and E. H. Veech, Freeze-blowing: A new technique for the study of brain in vivo, J. Neurochem. 20, 183-188 (1973).
    • (1973) J. Neurochem. , vol.20 , pp. 183-188
    • Veech, R.L.1    Harris, R.L.2    Veloso, D.3    Veech, E.H.4
  • 37
    • 0028020080 scopus 로고
    • Metabolic abnormalities and grade of encephalopathy in acute hepatic failure
    • A. M. Mans, M. R. DeJoseph, and R. A. Hawkins, Metabolic abnormalities and grade of encephalopathy in acute hepatic failure, J. Neurochem. 63, 1829-1838 (1994).
    • (1994) J. Neurochem. , vol.63 , pp. 1829-1838
    • Mans, A.M.1    DeJoseph, M.R.2    Hawkins, R.A.3
  • 38
    • 0026472783 scopus 로고
    • 1H NMR properties of N-acetylaspartylglutamate in extracts of nervous tissue of the rat
    • D. Holowenko, J. Peeling, and G. Sutherland, 1H NMR properties of N-acetylaspartylglutamate in extracts of nervous tissue of the rat, NMR Biomed. 5, 43-47 (1992).
    • (1992) NMR Biomed. , vol.5 , pp. 43-47
    • Holowenko, D.1    Peeling, J.2    Sutherland, G.3
  • 39
    • 0346147528 scopus 로고
    • Effect of insulin on nitrogenous constituents of rat brain
    • R. K. Shaw and J. D. Heine, Effect of insulin on nitrogenous constituents of rat brain, J. Neurochem. 12, 527-532 (1965).
    • (1965) J. Neurochem. , vol.12 , pp. 527-532
    • Shaw, R.K.1    Heine, J.D.2
  • 40
    • 0014757799 scopus 로고
    • Regional distribution and movement of amino acids in the brain
    • L. Battistin and A. Lajtha, Regional distribution and movement of amino acids in the brain, J. Neurol. Sci. 10, 313-322 (1970).
    • (1970) J. Neurol. Sci. , vol.10 , pp. 313-322
    • Battistin, L.1    Lajtha, A.2
  • 41
    • 0029367235 scopus 로고
    • Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo
    • Y. Nagatomo, M. Wick, F. Prielmeier, and J. Frahm, Dynamic monitoring of cerebral metabolites during and after transient global ischemia in rats by quantitative proton NMR spectroscopy in vivo, NMR Biomed. 8, 265-270 (1995).
    • (1995) NMR Biomed. , vol.8 , pp. 265-270
    • Nagatomo, Y.1    Wick, M.2    Prielmeier, F.3    Frahm, J.4
  • 42
    • 0009743529 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy: The new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?
    • B. D. Ross, E. R. Danielsen, and S. Bluml, Proton magnetic resonance spectroscopy: The new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?, Dig. Dis. 14(Suppl. 1), 30-39 (1996).
    • (1996) Dig. Dis. , vol.14 , Issue.1 SUPPL. , pp. 30-39
    • Ross, B.D.1    Danielsen, E.R.2    Bluml, S.3
  • 44
    • 0030695043 scopus 로고    scopus 로고
    • Homocarnosine and the measurement of neuronal pH in patients with epilepsy
    • D. L. Rothman, K. L. Behar, J. W. Prichard, and O. A. Petroff, Homocarnosine and the measurement of neuronal pH in patients with epilepsy, Magn. Reson. Med. 38, 924-929 (1997).
    • (1997) Magn. Reson. Med. , vol.38 , pp. 924-929
    • Rothman, D.L.1    Behar, K.L.2    Prichard, J.W.3    Petroff, O.A.4
  • 46
    • 0031687999 scopus 로고    scopus 로고
    • Simultaneous in vivo spectral editing and water suppression
    • M. Mescher, H. Merkle, J. Kirsch, M. Garwood, and R. Gruetter, Simultaneous in vivo spectral editing and water suppression, NMR Biomed. 11, 266-272 (1998).
    • (1998) NMR Biomed. , vol.11 , pp. 266-272
    • Mescher, M.1    Merkle, H.2    Kirsch, J.3    Garwood, M.4    Gruetter, R.5
  • 51
    • 85030062001 scopus 로고    scopus 로고
    • 1H NMR spectroscopy of brain glucose and metabolites
    • 1H NMR spectroscopy of brain glucose and metabolites, Magma 6(Suppl. 1), 9 (1998).
    • (1998) Magma , vol.6 , Issue.1 SUPPL. , pp. 9
    • Pfeuffer, J.1    Tkac, I.2    Gruetter, R.3
  • 52
    • 0031961946 scopus 로고    scopus 로고
    • Steady-state cerebral glucose concentrations and transport in the human brain
    • R. Gruetter, K. Ugurbil, and E. R. Seaquist, Steady-state cerebral glucose concentrations and transport in the human brain, J. Neurochem. 70, 397-408 (1998).
    • (1998) J. Neurochem. , vol.70 , pp. 397-408
    • Gruetter, R.1    Ugurbil, K.2    Seaquist, E.R.3
  • 53
    • 0000546318 scopus 로고
    • Optimization of homonuclear two-dimensional correlation methods for in vivo and ex vivo NMR
    • A. Ziegler, M. Izquierdo, C. Remy, and M. Decorps, Optimization of homonuclear two-dimensional correlation methods for in vivo and ex vivo NMR, J. Magn. Reson. B 107, 10-18 (1995).
    • (1995) J. Magn. Reson. B , vol.107 , pp. 10-18
    • Ziegler, A.1    Izquierdo, M.2    Remy, C.3    Decorps, M.4
  • 55
  • 57
    • 0031595057 scopus 로고    scopus 로고
    • 31P magnetic resonance spectroscopy reveals osmotic and metabolic disturbances in human hepatic encephalopathy
    • 31P magnetic resonance spectroscopy reveals osmotic and metabolic disturbances in human hepatic encephalopathy, J. Neurochem. 71, 1564-1576 (1998).
    • (1998) J. Neurochem. , vol.71 , pp. 1564-1576
    • Bluml, S.1    Zuckerman, E.2    Tan, J.3    Ross, B.D.4
  • 58
    • 0031821584 scopus 로고    scopus 로고
    • Proton spectroscopy without water suppression: The oversampled J- resolved experiment
    • R. E. Hurd, D. Gurr, and N. Sailasuta, Proton spectroscopy without water suppression: The oversampled J- resolved experiment, Magn. Reson. Med. 40, 343-347 (1998).
    • (1998) Magn. Reson. Med. , vol.40 , pp. 343-347
    • Hurd, R.E.1    Gurr, D.2    Sailasuta, N.3
  • 59
    • 0032899485 scopus 로고    scopus 로고
    • Detection of homonuclear decoupled in vivo proton NMR spectra using constant time chemical shift encoding: CT-PRESS
    • W. Dreher and D. Leibfritz, Detection of homonuclear decoupled in vivo proton NMR spectra using constant time chemical shift encoding: CT-PRESS, Magn. Reson. Imaging 17, 141-150 (1999).
    • (1999) Magn. Reson. Imaging , vol.17 , pp. 141-150
    • Dreher, W.1    Leibfritz, D.2


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