Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human β-amyloid

Journal of Neuroinflammation

Volumn 2, Issue , 2005, Pages

  Craft, Jeffrey M ^a,b   Watterson, D Martin ^a,b   Hirsch, Emmet ^b,c   Van Eldik, Linda J ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c Evanston Northwestern Healthcare ^*  (United States)

Author keywords

Alzheimer's disease; Amyloid beta; Animal model; Glial activation; Interleukin 1; Microglia

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN VENTRICLE; CELL ACTIVATION; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE PREDISPOSITION; DISEASE SEVERITY; HIPPOCAMPUS; IN VIVO STUDY; INFLAMMATION; KNOCKOUT MOUSE; MICROGLIA; MORTALITY; MOUSE; NERVE CELL LESION; NONHUMAN; SENILE PLAQUE; SIGNAL TRANSDUCTION; SYNAPSE; WILD TYPE;

EID: 27344441062     PISSN: 17422094     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-2-15     Document Type: Article

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