메뉴 건너뛰기




Volumn 102, Issue 2, 2014, Pages 174-185

Cilia and polycystic kidney disease, kith and kin

Author keywords

Cilia; Exocyst; Planar cell polarity; Polycystic kidney disease

Indexed keywords

EXOCYST; POLYCYSTIN 1; POLYCYSTIN 2; PROTEIN CDC42;

EID: 84903274476     PISSN: 1542975X     EISSN: 15429768     Source Type: Journal    
DOI: 10.1002/bdrc.21066     Document Type: Article
Times cited : (17)

References (96)
  • 1
    • 80051469652 scopus 로고    scopus 로고
    • Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles
    • Abdul-Majeed S, Nauli SM. 2011. Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles. Hypertension 58:325-31.
    • (2011) Hypertension , vol.58 , pp. 325-331
    • Abdul-Majeed, S.1    Nauli, S.M.2
  • 2
    • 84856360903 scopus 로고    scopus 로고
    • Stages of ciliogenesis and regulation of ciliary length
    • Avasthi P, Marshall WF. 2012. Stages of ciliogenesis and regulation of ciliary length. Differentiation 83:S30-42.
    • (2012) Differentiation , vol.83
    • Avasthi, P.1    Marshall, W.F.2
  • 3
    • 0035806961 scopus 로고    scopus 로고
    • The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway
    • Barr MM, DeModena J, Braun D, et al. 2001. The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway. Curr Biol 11:1341-6.
    • (2001) Curr Biol , vol.11 , pp. 1341-1346
    • Barr, M.M.1    DeModena, J.2    Braun, D.3
  • 4
    • 0033598394 scopus 로고    scopus 로고
    • A polycystic kidney-disease gene homologue required for male mating behaviour in C
    • Barr MM, Sternberg PW. 1999. A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans. Nature 401:386-9.
    • (1999) elegans. Nature , vol.401 , pp. 386-389
    • Barr, M.M.1    Sternberg, P.W.2
  • 5
    • 74449086803 scopus 로고    scopus 로고
    • Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation
    • Besschetnova TY, Kolpakova-Hart E, Guan Y, et al. 2010. Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr Biol 20:182-7.
    • (2010) Curr Biol , vol.20 , pp. 182-187
    • Besschetnova, T.Y.1    Kolpakova-Hart, E.2    Guan, Y.3
  • 6
    • 84883111223 scopus 로고    scopus 로고
    • Molecular basis of tubulin transport within the cilium by IFT74 and IFT81
    • Bhogaraju S, Cajanek L, Fort C, et al. 2013. Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science 341:1009-12.
    • (2013) Science , vol.341 , pp. 1009-1012
    • Bhogaraju, S.1    Cajanek, L.2    Fort, C.3
  • 7
    • 27744436054 scopus 로고    scopus 로고
    • Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis
    • Bisgrove BW, Snarr BS, Emrazian A, et al. 2005. Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev Biol 287:274-88.
    • (2005) Dev Biol , vol.287 , pp. 274-288
    • Bisgrove, B.W.1    Snarr, B.S.2    Emrazian, A.3
  • 8
    • 84885864917 scopus 로고    scopus 로고
    • IFT88 plays a Cilia- and PCP-independent role in controlling oriented cell divisions during vertebrate embryonic development
    • Borovina A, Ciruna B. 2013. IFT88 plays a Cilia- and PCP-independent role in controlling oriented cell divisions during vertebrate embryonic development. Cell Rep 5:37-43.
    • (2013) Cell Rep , vol.5 , pp. 37-43
    • Borovina, A.1    Ciruna, B.2
  • 9
    • 4243144134 scopus 로고    scopus 로고
    • Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization
    • Cano DA, Murcia NS, Pazour GJ, et al. 2004. Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development 131:3457-67.
    • (2004) Development , vol.131 , pp. 3457-3467
    • Cano, D.A.1    Murcia, N.S.2    Pazour, G.J.3
  • 10
    • 48349109103 scopus 로고    scopus 로고
    • Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome
    • Cantagrel V, Silhavy JL, Bielas SL, et al. 2008. Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome. Am J Hum Genet 83:170-9.
    • (2008) Am J Hum Genet , vol.83 , pp. 170-179
    • Cantagrel, V.1    Silhavy, J.L.2    Bielas, S.L.3
  • 11
    • 84884303444 scopus 로고    scopus 로고
    • Cdc42 deficiency causes ciliary abnormalities and cystic kidneys
    • Choi SY, Chacon-Heszele MF, Huang L, et al. 2013. Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. J Am Soc Nephrol 24:1435-50.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1435-1450
    • Choi, S.Y.1    Chacon-Heszele, M.F.2    Huang, L.3
  • 12
    • 84889094538 scopus 로고    scopus 로고
    • Compartmentalized calcium signaling in cilia regulates intraflagellar transport
    • Collingridge P, Brownlee C, Wheeler GL. 2013. Compartmentalized calcium signaling in cilia regulates intraflagellar transport. Curr Biol 23:2311-8.
    • (2013) Curr Biol , vol.23 , pp. 2311-2318
    • Collingridge, P.1    Brownlee, C.2    Wheeler, G.L.3
  • 13
    • 26644460824 scopus 로고    scopus 로고
    • Vertebrate smoothened functions at the primary cilium
    • Corbit KC, Aanstad P, Singla V, et al. 2005. Vertebrate smoothened functions at the primary cilium. Nature 437:1018-21.
    • (2005) Nature , vol.437 , pp. 1018-1021
    • Corbit, K.C.1    Aanstad, P.2    Singla, V.3
  • 15
    • 33846785192 scopus 로고    scopus 로고
    • Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells
    • Dawe HR, Farr H, Gull K. 2007. Centriole/basal body morphogenesis and migration during ciliogenesis in animal cells. J Cell Sci 120(Pt 1):7-15.
    • (2007) J Cell Sci , vol.120 , Issue.PART 1 , pp. 7-15
    • Dawe, H.R.1    Farr, H.2    Gull, K.3
  • 16
    • 33846646986 scopus 로고    scopus 로고
    • The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation
    • Dawe HR, Smith UM, Cullinane AR, et al. 2007. The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation. Hum Mol Genet 16:173-86.
    • (2007) Hum Mol Genet , vol.16 , pp. 173-186
    • Dawe, H.R.1    Smith, U.M.2    Cullinane, A.R.3
  • 17
    • 84862580595 scopus 로고    scopus 로고
    • Exome sequencing can improve diagnosis and alter patient management
    • 138ra78
    • Dixon-Salazar TJ, Silhavy JL, Udpa N, et al. 2012. Exome sequencing can improve diagnosis and alter patient management. Sci Transl Med 4:138ra78.
    • (2012) Sci Transl Med , vol.4
    • Dixon-Salazar, T.J.1    Silhavy, J.L.2    Udpa, N.3
  • 19
    • 70450176073 scopus 로고    scopus 로고
    • Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion
    • Duldulao NA, Lee S, Sun Z. 2009. Cilia localization is essential for in vivo functions of the Joubert syndrome protein Arl13b/Scorpion. Development 136:4033-42.
    • (2009) Development , vol.136 , pp. 4033-4042
    • Duldulao, N.A.1    Lee, S.2    Sun, Z.3
  • 20
    • 76649133765 scopus 로고    scopus 로고
    • Molecular mechanisms of protein and lipid targeting to ciliary membranes
    • Emmer BT, Maric D, Engman DM. 2010. Molecular mechanisms of protein and lipid targeting to ciliary membranes. J Cell Sci 123(Pt 4):529-36.
    • (2010) J Cell Sci , vol.123 , Issue.PART 4 , pp. 529-536
    • Emmer, B.T.1    Maric, D.2    Engman, D.M.3
  • 21
    • 29444450890 scopus 로고    scopus 로고
    • Defective planar cell polarity in polycystic kidney disease
    • Fischer E, Legue E, Doyen A, et al. 2006. Defective planar cell polarity in polycystic kidney disease. Nat Genet 38:21-3.
    • (2006) Nat Genet , vol.38 , pp. 21-23
    • Fischer, E.1    Legue, E.2    Doyen, A.3
  • 22
    • 79955634491 scopus 로고    scopus 로고
    • The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes
    • Fogelgren B, Lin SY, Zuo X, et al. 2011. The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes. PLoS Genet 7:e1001361.
    • (2011) PLoS Genet , vol.7
    • Fogelgren, B.1    Lin, S.Y.2    Zuo, X.3
  • 23
    • 33748327050 scopus 로고    scopus 로고
    • The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly
    • Follit JA, Tuft RA, Fogarty KE, et al. 2006. The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol Biol Cell 17:3781-92.
    • (2006) Mol Biol Cell , vol.17 , pp. 3781-3792
    • Follit, J.A.1    Tuft, R.A.2    Fogarty, K.E.3
  • 24
    • 75749089291 scopus 로고    scopus 로고
    • The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence
    • Follit JA, Li L, Vucica Y, et al. 2010. The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence. J Cell Biol 188:21-8.
    • (2010) J Cell Biol , vol.188 , pp. 21-28
    • Follit, J.A.1    Li, L.2    Vucica, Y.3
  • 25
    • 84863992161 scopus 로고    scopus 로고
    • Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access
    • Garcia-Gonzalo FR, Reiter JF. 2012. Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access. J Cell Biol 197:697-709.
    • (2012) J Cell Biol , vol.197 , pp. 697-709
    • Garcia-Gonzalo, F.R.1    Reiter, J.F.2
  • 27
    • 77951101203 scopus 로고    scopus 로고
    • The primary cilium: a signalling centre during vertebrate development
    • Goetz SC, Anderson KV. 2010. The primary cilium: a signalling centre during vertebrate development. Nat Rev Genet 11:331-44.
    • (2010) Nat Rev Genet , vol.11 , pp. 331-344
    • Goetz, S.C.1    Anderson, K.V.2
  • 28
    • 0034925405 scopus 로고    scopus 로고
    • Polycystic kidney disease: from the bedside to the gene and back
    • Grantham JJ. 2001. Polycystic kidney disease: from the bedside to the gene and back. Curr Opin Nephrol Hypertens 10:533-42.
    • (2001) Curr Opin Nephrol Hypertens , vol.10 , pp. 533-542
    • Grantham, J.J.1
  • 29
    • 0032577562 scopus 로고    scopus 로고
    • Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells
    • Grindstaff KK, Yeaman C, Anandasabapathy N, et al. 1998. Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell 93:731-40.
    • (1998) Cell , vol.93 , pp. 731-740
    • Grindstaff, K.K.1    Yeaman, C.2    Anandasabapathy, N.3
  • 30
    • 0033558093 scopus 로고    scopus 로고
    • The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis
    • Guo W, Roth D, Walch-Solimena C, et al. 1999. The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J 18:1071-80.
    • (1999) EMBO J , vol.18 , pp. 1071-1080
    • Guo, W.1    Roth, D.2    Walch-Solimena, C.3
  • 31
    • 40749144679 scopus 로고    scopus 로고
    • Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
    • Haycraft CJ, Banizs B, Aydin-Son Y, et al. 2005. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 1:e53.
    • (2005) PLoS Genet , vol.1
    • Haycraft, C.J.1    Banizs, B.2    Aydin-Son, Y.3
  • 32
    • 70949085969 scopus 로고    scopus 로고
    • Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse
    • Heydeck W, Zeng H, Liu A. 2009. Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse. Dev Dyn 238:3035-42.
    • (2009) Dev Dyn , vol.238 , pp. 3035-3042
    • Heydeck, W.1    Zeng, H.2    Liu, A.3
  • 33
    • 58149504281 scopus 로고    scopus 로고
    • Nephronophthisis: disease mechanisms of a ciliopathy
    • Hildebrandt F, Attanasio M, Otto E. 2009. Nephronophthisis: disease mechanisms of a ciliopathy. J Am Soc Nephrol 20:23-35.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 23-35
    • Hildebrandt, F.1    Attanasio, M.2    Otto, E.3
  • 35
    • 0030464563 scopus 로고    scopus 로고
    • The mammalian brain rsec6/8 complex
    • Hsu SC, Ting AE, Hazuka CD, et al. 1996. The mammalian brain rsec6/8 complex. Neuron 17:1209-19.
    • (1996) Neuron , vol.17 , pp. 1209-1219
    • Hsu, S.C.1    Ting, A.E.2    Hazuka, C.D.3
  • 36
    • 77954841928 scopus 로고    scopus 로고
    • A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution
    • Hu Q, Milenkovic L, Jin H, et al. 2010. A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. Science 329:436-9.
    • (2010) Science , vol.329 , pp. 436-439
    • Hu, Q.1    Milenkovic, L.2    Jin, H.3
  • 37
    • 0023557377 scopus 로고
    • Mapping of the Saccharomyces cerevisiae CDC3, CDC25, and CDC42 genes to chromosome XII by chromosome blotting and tetrad analysis
    • Johnson DI, Jacobs CW, Pringle JR, et al. 1987. Mapping of the Saccharomyces cerevisiae CDC3, CDC25, and CDC42 genes to chromosome XII by chromosome blotting and tetrad analysis. Yeast 3:243-53.
    • (1987) Yeast , vol.3 , pp. 243-253
    • Johnson, D.I.1    Jacobs, C.W.2    Pringle, J.R.3
  • 38
    • 0025363198 scopus 로고
    • Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity
    • Johnson DI, Pringle JR. 1990. Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity. J Cell Biol 111:143-52.
    • (1990) J Cell Biol , vol.111 , pp. 143-152
    • Johnson, D.I.1    Pringle, J.R.2
  • 39
    • 56149097603 scopus 로고    scopus 로고
    • Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
    • Jonassen JA, San Agustin J, Follit JA, et al. 2008. Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J Cell Biol 183:377-84.
    • (2008) J Cell Biol , vol.183 , pp. 377-384
    • Jonassen, J.A.1    San Agustin, J.2    Follit, J.A.3
  • 40
    • 37549052499 scopus 로고    scopus 로고
    • Ciliary proteins link basal body polarization to planar cell polarity regulation
    • Jones C, Roper VC, Foucher I, et al. 2008. Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet 40:69-77.
    • (2008) Nat Genet , vol.40 , pp. 69-77
    • Jones, C.1    Roper, V.C.2    Foucher, I.3
  • 41
    • 84874828473 scopus 로고    scopus 로고
    • The ciliary flow sensor and polycystic kidney disease
    • Kotsis F, Boehlke C, Kuehn EW. 2013. The ciliary flow sensor and polycystic kidney disease. Nephrol Dial Transplant 28:518-26.
    • (2013) Nephrol Dial Transplant , vol.28 , pp. 518-526
    • Kotsis, F.1    Boehlke, C.2    Kuehn, E.W.3
  • 42
    • 0036122434 scopus 로고    scopus 로고
    • Polycystin-2 is an intracellular calcium release channel
    • Koulen P, Cai Y, Geng L, et al. 2002. Polycystin-2 is an intracellular calcium release channel. Nat Cell Biol 4:191-7.
    • (2002) Nat Cell Biol , vol.4 , pp. 191-197
    • Koulen, P.1    Cai, Y.2    Geng, L.3
  • 44
    • 2342501364 scopus 로고    scopus 로고
    • Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene
    • Li JB, Gerdes JM, Haycraft CJ, et al. 2004. Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. Cell 117:541-52.
    • (2004) Cell , vol.117 , pp. 541-552
    • Li, J.B.1    Gerdes, J.M.2    Haycraft, C.J.3
  • 45
    • 0037884961 scopus 로고    scopus 로고
    • Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease
    • Lin F, Hiesberger T, Cordes K, et al. 2003. Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 100:5286-91.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5286-5291
    • Lin, F.1    Hiesberger, T.2    Cordes, K.3
  • 46
    • 0033638380 scopus 로고    scopus 로고
    • Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins
    • Lipschutz JH, Guo W, O'Brien LE, et al. 2000. Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins. Mol Biol Cell 11:4259-75.
    • (2000) Mol Biol Cell , vol.11 , pp. 4259-4275
    • Lipschutz, J.H.1    Guo, W.2    O'Brien, L.E.3
  • 47
    • 0037899298 scopus 로고    scopus 로고
    • The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum
    • Lipschutz JH, Lingappa VR, Mostov KE. 2003. The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum. J Biol Chem 278:20954-60.
    • (2003) J Biol Chem , vol.278 , pp. 20954-20960
    • Lipschutz, J.H.1    Lingappa, V.R.2    Mostov, K.E.3
  • 48
    • 0001647625 scopus 로고    scopus 로고
    • Exocytosis: the many masters of the exocyst
    • Lipschutz JH, Mostov KE. 2002. Exocytosis: the many masters of the exocyst. Curr Biol 12:R212-4.
    • (2002) Curr Biol , vol.12
    • Lipschutz, J.H.1    Mostov, K.E.2
  • 49
    • 0031941550 scopus 로고    scopus 로고
    • Molecular development of the kidney: a review of the results of gene disruption studies
    • Lipschutz JH. 1998. Molecular development of the kidney: a review of the results of gene disruption studies. Am J Kidney Dis 31:383-97.
    • (1998) Am J Kidney Dis , vol.31 , pp. 383-397
    • Lipschutz, J.H.1
  • 50
    • 34548429735 scopus 로고    scopus 로고
    • The proteome of the mouse photoreceptor sensory cilium complex
    • Liu Q, Tan G, Levenkova N, et al. 2007. The proteome of the mouse photoreceptor sensory cilium complex. Mol Cell Proteomics 6:1299-317.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1299-1317
    • Liu, Q.1    Tan, G.2    Levenkova, N.3
  • 51
    • 26844561983 scopus 로고    scopus 로고
    • Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice
    • Liu W, Murcia NS, Duan Y, et al. 2005. Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice. Am J Physiol Renal Physiol 289:F978-88.
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Liu, W.1    Murcia, N.S.2    Duan, Y.3
  • 52
    • 57149087523 scopus 로고    scopus 로고
    • Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors
    • Masyuk AI, Gradilone SA, Banales JM, et al. 2008. Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors. Am J Physiol Gastrointest Liver Physiol 295:G725-34.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.295
    • Masyuk, A.I.1    Gradilone, S.A.2    Banales, J.M.3
  • 53
    • 15844385078 scopus 로고    scopus 로고
    • PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
    • Mochizuki T, Wu G, Hayashi T, et al. 1996. PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science 272:1339-42.
    • (1996) Science , vol.272 , pp. 1339-1342
    • Mochizuki, T.1    Wu, G.2    Hayashi, T.3
  • 54
    • 0032504963 scopus 로고    scopus 로고
    • Cloning of inv, a gene that controls left/right asymmetry and kidney development
    • Mochizuki T, Saijoh Y, Tsuchiya K, et al. 1998. Cloning of inv, a gene that controls left/right asymmetry and kidney development. Nature 395:177-81.
    • (1998) Nature , vol.395 , pp. 177-181
    • Mochizuki, T.1    Saijoh, Y.2    Tsuchiya, K.3
  • 55
    • 34347400228 scopus 로고    scopus 로고
    • Differences in renal tubule primary cilia length in a mouse model of Bardet-Biedl syndrome
    • Mokrzan EM, Lewis JS, Mykytyn K. 2007. Differences in renal tubule primary cilia length in a mouse model of Bardet-Biedl syndrome. Nephron Exp Nephrol 106:e88-96.
    • (2007) Nephron Exp Nephrol , vol.106
    • Mokrzan, E.M.1    Lewis, J.S.2    Mykytyn, K.3
  • 56
    • 0037115494 scopus 로고    scopus 로고
    • Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
    • Morgan D, Eley L, Sayer J, et al. 2002. Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle. Hum Mol Genet 11:3345-50.
    • (2002) Hum Mol Genet , vol.11 , pp. 3345-3350
    • Morgan, D.1    Eley, L.2    Sayer, J.3
  • 58
    • 0028322016 scopus 로고
    • Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice
    • Moyer JH, Lee-Tischler MJ, Kwon HY, et al. 1994. Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264:1329-33.
    • (1994) Science , vol.264 , pp. 1329-1333
    • Moyer, J.H.1    Lee-Tischler, M.J.2    Kwon, H.Y.3
  • 59
    • 34250012834 scopus 로고    scopus 로고
    • A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis
    • Nachury MV, Loktev AV, Zhang Q, et al. 2007. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell 129:1201-13.
    • (2007) Cell , vol.129 , pp. 1201-1213
    • Nachury, M.V.1    Loktev, A.V.2    Zhang, Q.3
  • 60
    • 0037317302 scopus 로고    scopus 로고
    • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
    • Nauli SM, Alenghat FJ, Luo Y, et al. 2003. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 33:129-37.
    • (2003) Nat Genet , vol.33 , pp. 129-137
    • Nauli, S.M.1    Alenghat, F.J.2    Luo, Y.3
  • 61
    • 0018930046 scopus 로고
    • Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway
    • Novick P, Field C, Schekman R. 1980. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21:205-15.
    • (1980) Cell , vol.21 , pp. 205-215
    • Novick, P.1    Field, C.2    Schekman, R.3
  • 62
    • 0041592700 scopus 로고    scopus 로고
    • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
    • Otto EA, Schermer B, Obara T, et al. 2003. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet 34:413-20.
    • (2003) Nat Genet , vol.34 , pp. 413-420
    • Otto, E.A.1    Schermer, B.2    Obara, T.3
  • 63
    • 33644624937 scopus 로고    scopus 로고
    • Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
    • Park TJ, Haigo SL, Wallingford JB. 2006. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet 38:303-11.
    • (2006) Nat Genet , vol.38 , pp. 303-311
    • Park, T.J.1    Haigo, S.L.2    Wallingford, J.B.3
  • 64
    • 44349116202 scopus 로고    scopus 로고
    • Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
    • Patel V, Li L, Cobo-Stark P, et al. 2008. Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet 17:1578-90.
    • (2008) Hum Mol Genet , vol.17 , pp. 1578-1590
    • Patel, V.1    Li, L.2    Cobo-Stark, P.3
  • 65
    • 0034735526 scopus 로고    scopus 로고
    • Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella
    • Pazour GJ, Dickert BL, Vucica Y, et al. 2000. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. J Cell Biol 151:709-18.
    • (2000) J Cell Biol , vol.151 , pp. 709-718
    • Pazour, G.J.1    Dickert, B.L.2    Vucica, Y.3
  • 67
    • 0037018850 scopus 로고    scopus 로고
    • The ion channel polycystin-2 is required for left-right axis determination in mice
    • Pennekamp P, Karcher C, Fischer A, et al. 2002. The ion channel polycystin-2 is required for left-right axis determination in mice. Curr Biol 12:938-43.
    • (2002) Curr Biol , vol.12 , pp. 938-943
    • Pennekamp, P.1    Karcher, C.2    Fischer, A.3
  • 68
    • 0031453864 scopus 로고    scopus 로고
    • Confocal analysis of primary cilia structure and colocalization with the Golgi apparatus in chondrocytes and aortic smooth muscle cells
    • Poole CA, Jensen CG, Snyder JA, et al. 1997. Confocal analysis of primary cilia structure and colocalization with the Golgi apparatus in chondrocytes and aortic smooth muscle cells. Cell Biol Int 21:483-94.
    • (1997) Cell Biol Int , vol.21 , pp. 483-494
    • Poole, C.A.1    Jensen, C.G.2    Snyder, J.A.3
  • 69
    • 0035498717 scopus 로고    scopus 로고
    • Bending the MDCK cell primary cilium increases intracellular calcium
    • Praetorius HA, Spring KR. 2001. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 184:71-9.
    • (2001) J Membr Biol , vol.184 , pp. 71-79
    • Praetorius, H.A.1    Spring, K.R.2
  • 70
    • 0037557518 scopus 로고    scopus 로고
    • Removal of the MDCK cell primary cilium abolishes flow sensing
    • Praetorius HA, Spring KR. 2003. Removal of the MDCK cell primary cilium abolishes flow sensing. J Membr Biol 191:69-76.
    • (2003) J Membr Biol , vol.191 , pp. 69-76
    • Praetorius, H.A.1    Spring, K.R.2
  • 73
    • 19044374304 scopus 로고    scopus 로고
    • Intraflagellar transport
    • Rosenbaum J. 2002. Intraflagellar transport. Curr Biol 12:R125.
    • (2002) Curr Biol , vol.12
    • Rosenbaum, J.1
  • 74
    • 48349125616 scopus 로고    scopus 로고
    • Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
    • Saburi S, Hester I, Fischer E, et al. 2008. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet 40:1010-5.
    • (2008) Nat Genet , vol.40 , pp. 1010-1015
    • Saburi, S.1    Hester, I.2    Fischer, E.3
  • 75
    • 0023568404 scopus 로고
    • Early organogenesis of the kidney
    • Saxen L, Sariola H. 1987. Early organogenesis of the kidney. Pediatr Nephrol 1:385-92.
    • (1987) Pediatr Nephrol , vol.1 , pp. 385-392
    • Saxen, L.1    Sariola, H.2
  • 76
    • 34248597580 scopus 로고    scopus 로고
    • Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw
    • Schottenfeld J, Sullivan-Brown J, Burdine RD. 2007. Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development 134:1605-15.
    • (2007) Development , vol.134 , pp. 1605-1615
    • Schottenfeld, J.1    Sullivan-Brown, J.2    Burdine, R.D.3
  • 77
    • 77951895173 scopus 로고    scopus 로고
    • Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia
    • Shiba D, Manning DK, Koga H, et al. 2010. Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia. Cytoskeleton (Hoboken) 67:112-9.
    • (2010) Cytoskeleton (Hoboken) , vol.67 , pp. 112-119
    • Shiba, D.1    Manning, D.K.2    Koga, H.3
  • 78
    • 20944435539 scopus 로고    scopus 로고
    • Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
    • Simons M, Gloy J, Ganner A, et al. 2005. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 37:537-43.
    • (2005) Nat Genet , vol.37 , pp. 537-543
    • Simons, M.1    Gloy, J.2    Ganner, A.3
  • 79
    • 58149185543 scopus 로고    scopus 로고
    • Planar cell polarity signaling: from fly development to human disease
    • Simons M, Mlodzik M. 2008. Planar cell polarity signaling: from fly development to human disease. Annu Rev Genet 42:517-40.
    • (2008) Annu Rev Genet , vol.42 , pp. 517-540
    • Simons, M.1    Mlodzik, M.2
  • 80
    • 0001577217 scopus 로고
    • Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells
    • Sorokin S. 1962. Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells. J Cell Biol 15:363-77.
    • (1962) J Cell Biol , vol.15 , pp. 363-377
    • Sorokin, S.1
  • 81
    • 0014291368 scopus 로고
    • Reconstructions of centriole formation and ciliogenesis in mammalian lungs
    • Sorokin SP. 1968. Reconstructions of centriole formation and ciliogenesis in mammalian lungs. J Cell Sci 3:207-30.
    • (1968) J Cell Sci , vol.3 , pp. 207-230
    • Sorokin, S.P.1
  • 82
    • 4544383179 scopus 로고    scopus 로고
    • A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
    • Sun Z, Amsterdam A, Pazour GJ, et al. 2004. A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development 131:4085-93.
    • (2004) Development , vol.131 , pp. 4085-4093
    • Sun, Z.1    Amsterdam, A.2    Pazour, G.J.3
  • 83
    • 0035159015 scopus 로고    scopus 로고
    • Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
    • Taulman PD, Haycraft CJ, Balkovetz DF, et al. 2001. Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 12:589-99.
    • (2001) Mol Biol Cell , vol.12 , pp. 589-599
    • Taulman, P.D.1    Haycraft, C.J.2    Balkovetz, D.F.3
  • 84
    • 0029002967 scopus 로고
    • Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. The International Polycystic Kidney Disease Consortium
    • The International Polycystic Kidney Disease Consortium
    • The International Polycystic Kidney Disease Consortium. 1995. Polycystic kidney disease: the complete structure of the PKD1 gene and its protein. The International Polycystic Kidney Disease Consortium. Cell 81:289-98.
    • (1995) Cell , vol.81 , pp. 289-298
  • 86
    • 54049087300 scopus 로고    scopus 로고
    • Dishevelled links basal body docking and orientation in ciliated epithelial cells
    • Vladar EK, Axelrod JD. 2008. Dishevelled links basal body docking and orientation in ciliated epithelial cells. Trends Cell Biol 18:517-20.
    • (2008) Trends Cell Biol , vol.18 , pp. 517-520
    • Vladar, E.K.1    Axelrod, J.D.2
  • 87
    • 0016705067 scopus 로고
    • Fine structure of mammalian renal cilia
    • Webber WA, Lee J. 1975. Fine structure of mammalian renal cilia. Anat Rec 182:339-43.
    • (1975) Anat Rec , vol.182 , pp. 339-343
    • Webber, W.A.1    Lee, J.2
  • 88
    • 76049118573 scopus 로고    scopus 로고
    • The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis
    • Wu H, Turner C, Gardner J, et al. 2010. The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis. Mol Biol Cell 21:430-42.
    • (2010) Mol Biol Cell , vol.21 , pp. 430-442
    • Wu, H.1    Turner, C.2    Gardner, J.3
  • 89
    • 27144456598 scopus 로고    scopus 로고
    • Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo
    • Wu S, Mehta SQ, Pichaud F, et al. 2005. Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo. Nat Struct Mol Biol 12:879-85.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 879-885
    • Wu, S.1    Mehta, S.Q.2    Pichaud, F.3
  • 90
    • 0036785149 scopus 로고    scopus 로고
    • The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia
    • Yoder BK, Hou X, Guay-Woodford LM. 2002. The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia. J Am Soc Nephrol 13:2508-16.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2508-2516
    • Yoder, B.K.1    Hou, X.2    Guay-Woodford, L.M.3
  • 91
    • 0027158027 scopus 로고
    • Reversal of left-right asymmetry: a situs inversus mutation
    • Yokoyama T, Copeland NG, Jenkins NA, et al. 1993. Reversal of left-right asymmetry: a situs inversus mutation. Science 260:679-82.
    • (1993) Science , vol.260 , pp. 679-682
    • Yokoyama, T.1    Copeland, N.G.2    Jenkins, N.A.3
  • 92
    • 0028282550 scopus 로고
    • Mapping of the gene for autosomal recessive polycystic kidney disease (ARPKD) to chromosome 6p21-cen
    • Zerres K, Mucher G, Bachner L, et al. 1994. Mapping of the gene for autosomal recessive polycystic kidney disease (ARPKD) to chromosome 6p21-cen. Nat Genet 7:429-32.
    • (1994) Nat Genet , vol.7 , pp. 429-432
    • Zerres, K.1    Mucher, G.2    Bachner, L.3
  • 93
    • 5644261225 scopus 로고    scopus 로고
    • Sec15 is an effector for the Rab11 GTPase in mammalian cells
    • Zhang XM, Ellis S, Sriratana A, et al. 2004. Sec15 is an effector for the Rab11 GTPase in mammalian cells. J Biol Chem 279:43027-34.
    • (2004) J Biol Chem , vol.279 , pp. 43027-43034
    • Zhang, X.M.1    Ellis, S.2    Sriratana, A.3
  • 94
    • 84951612651 scopus 로고
    • Beitrage Zur Kenntniss einiger Drusen und epithelien
    • Zimmermann K. 1898. Beitrage Zur Kenntniss einiger Drusen und epithelien. Arch Mikrosk Anat 52:552-706.
    • (1898) Arch Mikrosk Anat , vol.52 , pp. 552-706
    • Zimmermann, K.1
  • 95
    • 79959358443 scopus 로고    scopus 로고
    • The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells
    • Zuo X, Fogelgren B, Lipschutz JH. 2011. The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells. J Biol Chem 286:22469-77.
    • (2011) J Biol Chem , vol.286 , pp. 22469-22477
    • Zuo, X.1    Fogelgren, B.2    Lipschutz, J.H.3
  • 96
    • 66249115336 scopus 로고    scopus 로고
    • The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro
    • Zuo X, Guo W, Lipschutz JH. 2009. The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro. Mol Biol Cell 20:2522-9.
    • (2009) Mol Biol Cell , vol.20 , pp. 2522-2529
    • Zuo, X.1    Guo, W.2    Lipschutz, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.