The exocyst protein sec10 interacts with polycystin-2 and knockdown causes PKD-phenotypes

PLoS Genetics

Volumn 7, Issue 4, 2011, Pages

  Fogelgren, Ben ^a   Lin, Shin Yi ^b   Zuo, Xiaofeng ^a   Jaffe, Kimberly M ^b   Park, Kwon Moo ^a,c   Reichert, Ryan J ^d   Bell, P Darwin ^d   Burdine, Rebecca D ^b   Lipschutz, Joshua H ^a,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c Kyungpook National University   (South Korea)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; EXOCYST; MITOGEN ACTIVATED PROTEIN KINASE; POLYCYSTIN 2; PROTEIN SEC10; UNCLASSIFIED DRUG; CARRIER PROTEIN; EXOC5 PROTEIN, HUMAN; IFT20 PROTEIN, HUMAN; IFT88 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN; SEC10 PROTEIN, ZEBRAFISH; TUMOR SUPPRESSOR PROTEIN; VESICULAR TRANSPORT PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; ENZYME ACTIVATION; EUKARYOTIC FLAGELLUM; GENE INTERACTION; IN VIVO STUDY; KIDNEY POLYCYSTIC DISEASE; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; ZEBRA FISH; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL STRAIN HEK293; DOG; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; KIDNEY; METABOLISM; MOUSE; PATHOLOGY; PRENATAL DEVELOPMENT; PROTEIN BINDING;

DANIO RERIO;

ANIMALS; CARRIER PROTEINS; CELL LINE; CILIA; DOGS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; KIDNEY; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; PHENOTYPE; POLYCYSTIC KIDNEY DISEASES; PROTEIN BINDING; TRPP CATION CHANNELS; TUMOR SUPPRESSOR PROTEINS; VESICULAR TRANSPORT PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79955634491     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001361     Document Type: Article

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