RFamide peptides 43RFa and 26RFa both promote survival of pancreatic β-cells and human pancreatic islets but exert opposite effects on insulin secretion

Diabetes

Volumn 63, Issue 7, 2014, Pages 2280-2393

  Granata, Riccarda ^a   Settanni, Fabio ^a   Trovato, Letizia ^a   Gallo, Davide ^a   Gesmundo, Iacopo ^a   Nano, Rita ^b   Gallo, Maria Pia ^c   Bergandi, Loredana ^a   Volante, Marco ^a   Alloatti, Giuseppe ^c   Piemonti, Lorenzo ^b   Leprince, Jérôme ^d   Papotti, Mauro ^a   Vaudry, Hubert ^d   Ong, Huy ^e   Ghigo, Ezio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d UNIVERSITY OF ROUEN   (France)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

26RFA PEPTIDE; 43RFA PEPTIDE; CYCLIC AMP; EXENDIN 4; GLUCOSE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 43RFA PEPTIDE, HUMAN; G PROTEIN COUPLED RECEPTOR; NEUROPEPTIDE; PREPRO 26RFA PROTEIN, HUMAN; PREPRO-26RFA PROTEIN, HUMAN; QRFP PEPTIDE; QRFPR PROTEIN, HUMAN; RFAMIDE PEPTIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; GLUCOSE TRANSPORT; GLUCOTOXICITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN LIKE ACTIVITY; INSULIN RELEASE; LIPOTOXICITY; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STARVATION; ANIMAL; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; NEUROPEPTIDES; PEPTIDES; RATS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84903158684     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1522     Document Type: Article

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